公开(公告)号：US06656712B1

公开(公告)日：2003-12-02

申请号：US09673668

申请日：2000-12-01

申请人： Fabrice Balavoine ,  Charles Miokowski ,  Patrick Schultz ,  Cyrille Richard

发明人： Fabrice Balavoine ,  Charles Miokowski ,  Patrick Schultz ,  Cyrille Richard

IPC分类号： C12N1114

CPC分类号： C07D495/04 ,  B82Y30/00 ,  C07C233/40 ,  C07C235/20 ,  C07C2603/24 ,  C07C2603/54 ,  C07F1/005 ,  C07F15/045 ,  C30B7/00 ,  C30B29/58 ,  G01N33/54353 ,  G01N33/54373 ,  G01N33/551 ,  Y10S977/729 ,  Y10S977/742 ,  Y10S977/746 ,  Y10S977/747 ,  Y10S977/793 ,  Y10S977/842 ,  Y10S977/848 ,  Y10S977/894 ,  Y10S977/896 ,  Y10S977/898 ,  Y10S977/92

摘要： Method for the attachment and/or crystallization of macromolecules, chemical reagents used in the said method, products obtained as well as applications of the said products in the field of materials and of structural biology, in particular as biosensors or as biomaterials. The said method comprises essentially the incubation, without stirring, for at least 15 minutes, of a biological macromolecule in solution with nanotubes of carbon closed at their ends, under suitable temperature and pH conditions.

摘要翻译： 用于大分子的附着和/或结晶的方法，所述方法中使用的化学试剂，获得的产物以及所述产品在材料和结构生物学领域的应用，特别是作为生物传感器或生物材料。所述方法 在适当的温度和pH条件下基本上包括在其末端封闭碳纳米管的情况下，不搅拌至少15分钟孵育溶液中的生物大分子。