公开(公告)号：US6063939A

公开(公告)日：2000-05-16

申请号：US226144

申请日：1999-01-07

Applicant: Carsten Groning ,  Michael Hesse ,  Daniel Heineke ,  Heinz-Josef Kneuper ,  Gerhard Fritz

Inventor： Carsten Groning ,  Michael Hesse ,  Daniel Heineke ,  Heinz-Josef Kneuper ,  Gerhard Fritz

IPC: B01J23/89 ,  B01J27/045 ,  C07D309/18 ,  C07D507/02 ,  C07D309/00 ,  C07D319/12

CPC classification number: B01J27/045 ,  B01J23/8913 ,  C07D309/18

Abstract: Unsaturated cyclic ethers of the formula I ##STR1## whereZ is --(CHR.sup.4).sub.q -- or --(CHR.sup.4).sub.q --O--,q is 0, 1, 2 or 3 andR.sup.1,R.sup.2,R.sup.3,R.sup.4 are hydrogen or C.sub.1 -C.sub.4 -alkylare prepared by reacting diols of the formula II ##STR2## where Z, R.sup.1, R.sup.2 and R.sup.3 are as defined above, in the liquid phase at from 150 to 300.degree. C. in the presence of a cobalt-containing supported catalyst which has not been activated by reduction before use and comprises cobalt and a noble metal selected from the group consisting of platinum, palladium, rhodium, iridium, ruthenium, osmium, rhenium or a mixture thereof applied by sol impregnation on an inert support, wherein the supported catalyst is doped with sulfur. Sulfur-doped supported catalysts comprising cobalt and noble metals are also provided.

Abstract translation: Z为 - （CHR 4）q-或 - （CHR 4）q O - ，q为0,1,2或3且R 1，R 2，R 3，R 4为氢或C 1 -C 4烷基的式I的不饱和环醚为 通过使其中Z，R 1，R 2和R 3如上所定义的式II的二醇在150-300℃的液相中，在没有被还原活化的含钴担载催化剂存在下反应制备 并且包括钴和选自铂，钯，铑，铱，钌，锇，铼的贵金属或其通过溶胶浸渍施加到惰性载体上的混合物，其中负载型催化剂掺杂有硫。 还提供了包含钴和贵金属的硫掺杂负载型催化剂。

公开(公告)号：US5877326A

公开(公告)日：1999-03-02

申请号：US914187

申请日：1997-08-19

Applicant: Gisela Hieber ,  Klaus Ebel ,  Jurgen Schroder ,  Toni Dockner ,  Carsten Groning ,  Bernd Ruge

Inventor： Gisela Hieber ,  Klaus Ebel ,  Jurgen Schroder ,  Toni Dockner ,  Carsten Groning ,  Bernd Ruge

IPC: C07D233/58 ,  B01J21/12 ,  B01J27/16 ,  C07D233/54 ,  C07D233/68 ,  C07D233/90 ,  C07D233/91 ,  C07D233/92 ,  C07D235/06 ,  C07D235/08 ,  C07D233/56

CPC classification number: C07D235/08 ,  C07D233/54 ,  C07D233/56 ,  C07D233/64 ,  C07D233/68 ,  C07D233/90 ,  C07D233/91 ,  C07D233/92 ,  C07D235/06

Abstract: A process for preparing substituted imidazoles of the formula I ##STR1## R.sup.1, R.sup.2 and R.sup.3 are identical or different and are each hydrogen, halogen, NO.sub.2, CN or a C.sub.1 -C.sub.20 -hydrocarbon radical which is unsubstituted or substituted by one or more halogens or R.sup.1 and R.sup.2 together are members of a 3- to 20-membered hydrocarbon ring which is unsubstituted or substituted by one or more halogens and/or C.sub.1 -C.sub.8 -alkyl groups and which may contain 1, 2 or 3 heteroatoms from the group consisting of nitrogen, oxygen and sulfur, andR.sup.4 is a C.sub.1 -C.sub.20 -hydrocarbon radical which is unsubstituted or substituted by one or more halogens,comprises using an aqueous phase of the imidazoles of the formula II ##STR2## where R.sup.1, R.sup.2 and R.sup.3 are as defined above with compounds of the formula IIIR.sup.4 --O--R.sup.5 IIIwhereR.sup.4 is as defined above andR.sup.5 is hydrogen or R.sup.4, it being possible in the latter case for the two R.sup.4 substituents to be identical or different,and reacting it at from 200.degree. to 550.degree. C. in the presence of a catalyst comprising oxides and/or phosphates of one or more metals of the 2nd, 3rd and 4th main group and the 4th subgroup of the Periodic Table in the presence or absence of phosphoric acid and/or phosphoric esters.

Abstract translation: 制备式I的取代咪唑的方法R1，R2和R3相同或不同，各自为氢，卤素，NO2，CN或C1-C20-烃基，其未被取代或被一个或多个 卤素或R 1和R 2一起是3至20元烃环的成员，其未被取代或被一个或多个卤素和/或C 1 -C 8烷基取代，并且可以含有1,2或3个来自该基团的杂原子 由氮，氧和硫组成，R4是未被取代或被一个或多个卤素取代的C 1 -C 20烃基，包括使用式II的咪唑的水相，其中R 1，R 2和 R 3如上所定义，与式III的R4-O-R5III化合物，其中R 4如上定义，R 5是氢或R 4，在后一种情况下，两个R 4取代基可以相同或不同， 在约200℃〜550℃下， 在磷酸和/或磷酸酯存在或不存在的条件下，包含第2，第3和第4主族和第4族的周期表中的一种或多种金属的氧化物和/或磷酸盐。

公开(公告)号：US6166223A

公开(公告)日：2000-12-26

申请号：US459722

申请日：1999-12-13

Applicant: Carsten Groning ,  Reinhard Kemper ,  Markus Frede ,  Klaus Ebel

Inventor： Carsten Groning ,  Reinhard Kemper ,  Markus Frede ,  Klaus Ebel

IPC: C07D207/32 ,  C07D207/323

CPC classification number: C07D207/323

Abstract: A process for the preparation of 2,4-dimethylpyrrole is described in which a 2,4-dimethyl-3,5-bisalkoxycarbonylpyrrole is refluxed with from 10 to 30% strength aqueous alkali metal hydroxide solution until the solid has passed into solution, the reaction mixture is neutralized with acid and the mixture is refluxed further until decarboxylation is complete. The process makes it possible to work under significantly milder, less aggressive conditions than are known from the prior art.

Abstract translation: 描述了制备2,4-二甲基吡咯的方法，其中2,4-二甲基-3,5-双烷氧基羰基吡咯与10-30％强度的碱金属氢氧化碱水溶液回流直到固体已经进入溶液， 反应混合物用酸中和，混合物进一步回流直到脱羧完成。 该方法使得可以在比现有技术已知的明显更温和，较不具有侵蚀性的条件下工作。

公开(公告)号：US5840894A

公开(公告)日：1998-11-24

申请号：US668140

申请日：1996-06-21

Applicant: Regina Schneider ,  Johann-Peter Melder ,  Joaquim Henrique Teles ,  Carsten Groning ,  Klaus Ebel

Inventor： Regina Schneider ,  Johann-Peter Melder ,  Joaquim Henrique Teles ,  Carsten Groning ,  Klaus Ebel

IPC: C07D249/08 ,  C07D249/12 ,  C07D249/16

CPC classification number: C07D249/08 ,  C07D249/12

Abstract: A process for the preparation of 1,2,4-triazolium salts Ia ##STR1## where R.sup.1, and R.sup.2 and R.sup.3 are C-organic radicals, it being possible for R.sup.2 and R.sup.3 to be connected to give a 5- to 8-membered ring, R.sup.4 is hydrogen or an organic radical and A is an equivalent of an anion, by reacting an amidrazone II ##STR2## with a carboxylic acid III R.sup.4 --COOH II or a functional derivative (IIIa) of this acid, an anion A being formed from III or IIIa which, optionally, can be replaced by another anion. The triazolium salts have great industrial importance as catalysts for the preparation of acyloine from aldehydes.

Abstract translation: 一种制备1,2,4-三唑鎓盐的方法，其中R 1和R 2和R 3是C - 有机基团，可以将R 2和R 3连接，得到5-至8- R4是氢或有机基团，A是阴离子的当量，通过使氨基腙II Ib与羧酸III R4-COOH II或该酸的官能衍生物（IIIa）反应，阴离子 A由III或IIIa形成，任选地可以被另一个阴离子代替。 三唑鎓盐作为用于从醛制备偶剂的催化剂具有很大的工业重要性。

公开(公告)号：US6013842A

公开(公告)日：2000-01-11

申请号：US978010

申请日：1997-11-25

Applicant: Carsten Groning ,  Jorg Therre ,  Gerd Kaibel ,  Klaus Ebel

Inventor： Carsten Groning ,  Jorg Therre ,  Gerd Kaibel ,  Klaus Ebel

IPC: B01J31/08 ,  C07B61/00 ,  C07C45/39 ,  C07C45/52 ,  C07C45/71 ,  C07C47/198 ,  C07C45/64

CPC classification number: C07C45/71

Abstract: A process for preparing glyoxal monoacetals of the formula I, ##STR1## where R.sup.1 and R.sup.2, which can be identical or different, are C.sub.1 -C.sub.4 alkyl or C.sub.2 -C.sub.4 alkenyl involves reacting a mixture of glyoxal and glyoxal bisacetals of the formula II, ##STR2## where R.sup.1 and R.sup.2 have the meaning given above, with an excess of an alcohol of the formula R.sup.1 OH or R.sup.2 OH or mixtures of these in the presence of an acid catalyst until reaction equilibrium is achieved.

Abstract translation: 制备式I的乙二醛单缩醛的方法，其中可以相同或不同的R 1和R 2是C 1 -C 4烷基或C 2 -C 4烯基包括使式II的乙二醛和乙二醛双缩醛的混合物反应，其中R 1和 R2具有上面给出的含义，过量的式R 1 OH或R 2 OH的醇或它们的混合物在酸催化剂的存在下直到反应平衡为止。