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公开(公告)号：US11213565B2
公开(公告)日：2022-01-04
申请号：US16303208
申请日：2017-02-15
发明人： Myung Jun Chung
IPC分类号： A61K38/00 , A61P35/00 , A61K38/16 , A61K35/744 , A23L33/18 , C07K14/335 , C12N15/74 , A61K35/00
摘要： The present invention relates to a protein derived from lactic acid bacteria and a method for producing the same. The lactic acid bacteria-derived protein of the present invention is a purified protein isolated from lactic acid bacteria (Lactobacillus rhamnosus) having an excellent therapeutic effect against colorectal cancer. It has been demonstrated to have a remarkable effect against colorectal diseases, and thus is expected to be widely used as a natural protein therapeutic agent against colorectal diseases in the medical field.
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公开(公告)号：US11026983B2
公开(公告)日：2021-06-08
申请号：US16382669
申请日：2019-04-12
发明人： Myung Jun Chung
IPC分类号： A61K35/745 , A23L33/135 , C12N1/20 , C12R1/01
摘要： The present invention relates to a novel Bifidobacterium strain having an excellent growth promoting effect, and a nutraceutical composition for promotion of growth, which contains the strain. The strain of the present invention has a beneficial effect of promoting growth by promoting the digestion of human milk oligosaccharides to enhance immunity together with physical strength.
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公开(公告)号：US20190328800A1
公开(公告)日：2019-10-31
申请号：US16471872
申请日：2018-10-16
发明人： Myung Jun CHUNG
摘要： The present invention relates to a gene expression cassette including a strong promoter derived from lactic acid bacteria, and a gene expression vector including the same. According to the present invention, a large amount of a human protein, the physiological activity of which has been verified, may be stably produced with high efficiency by introducing a useful foreign gene into an expression vector and transforming probiotics with the expression vector. Through the production of this protein, it is possible to provide a basis for developing functional probiotics and making products using them.
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4.发明申请公开(公告)号：US20180125901A1
公开(公告)日：2018-05-10
申请号：US15801941
申请日：2017-11-02
发明人： Myung Jun CHUNG
IPC分类号： A61K35/744 , A61P3/04 , A61K35/747 , A61K9/00 , A61K31/51 , A61K31/525 , A61K31/455 , A61K31/4415 , A61K31/4188 , A61K31/07 , A61K31/355 , A61K31/375 , A61K31/59
CPC分类号： A61K35/744 , A61K9/0053 , A61K31/015 , A61K31/047 , A61K31/07 , A61K31/122 , A61K31/14 , A61K31/197 , A61K31/355 , A61K31/375 , A61K31/4188 , A61K31/4415 , A61K31/455 , A61K31/51 , A61K31/519 , A61K31/525 , A61K31/59 , A61K31/592 , A61K31/593 , A61K31/714 , A61K35/74 , A61K35/747 , A61K45/06 , A61K2035/11 , A61P1/16 , A61P3/00 , A61P3/02 , A61P3/04 , A61P3/06 , A61P3/08 , A61P3/10 , A61P9/12 , A61P19/08 , A61P19/10 , A61K2300/00
摘要： The present invention relates to a functional composition for preventing, alleviating or treating bone disease and lipid-related metabolic disease, and more particularly to a composition which comprises a combination of probiotics and a vitamin complex, which is capable of effectively preventing, alleviating or treating bone disease, obesity and lipid-related metabolic disease by synergistic effects on antioxidant activity, a reduction in blood lipid levels and the promotion of in vivo absorption of calcium and iron.
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公开(公告)号：US20180117102A1
公开(公告)日：2018-05-03
申请号：US15801875
申请日：2017-11-02
发明人： Myung Jun CHUNG
IPC分类号： A61K35/747 , A61K35/744 , A61K31/51 , A61K31/525 , A61K31/675 , A61K31/4188 , A61P3/04 , A61P3/10 , A61P3/06 , A61P1/16 , A61P9/10 , A61P9/12 , A61P9/00
摘要： The present invention provides a pharmaceutical composition and a food composition for preventing or treating lipid-related metabolic disease, which contain, as active ingredients, probiotics and a vitamin B complex. When the composition comprising the probiotics and the vitamin B complex is used, it may further promote in vivo absorption of the vitamin B complex, and may induce a synergistic effect on a reduction in blood lipid levels, thereby exhibiting an effect on the alleviation, prevention or treatment of obesity and lipid-related metabolic disease.
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公开(公告)号：US20210204583A1
公开(公告)日：2021-07-08
申请号：US16952635
申请日：2020-11-19
发明人： Myung Jun Chung
IPC分类号： A23L33/135 , A61P15/00 , A61K35/745 , A61K35/747
摘要： The present disclosure relates to a composition for preventing, relieving or treating climacteric symptoms, the composition comprising lactic acid bacteria and prebiotic composition. The lactic acid bacteria of the present disclosure have β-glucosidase activity and a very excellent ability to convert isoflavones into equol compounds, and thus may exhibit estrogenic activity through synergism with the gut microbiota. Therefore, the lactic acid bacteria of the present disclosure may be effectively used for the prevention, relief or treatment of women's climacteric or menopausal symptoms.
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公开(公告)号：US20180117103A1
公开(公告)日：2018-05-03
申请号：US15801980
申请日：2017-11-02
发明人： Myung Jun CHUNG
IPC分类号： A61K35/747 , A61K35/744 , A61K8/99 , A61K8/67 , A61K31/375 , A61Q19/08 , A61P35/00 , A61P37/08 , A61P17/00
CPC分类号： A61K35/747 , A61K8/676 , A61K8/99 , A61K31/375 , A61K35/741 , A61K35/744 , A61P17/00 , A61P17/18 , A61P35/00 , A61P37/08 , A61Q19/08 , A61K2300/00
摘要： The present invention provides an antioxidant composition and/or a composition for improving skin conditions, which contain, as active ingredients, probiotics and vitamin C. The composition containing probiotics and vitamin C as active ingredients according to the present invention can exhibit a synergistic effect on the activation of antioxidant enzyme, thereby exhibiting an antioxidant effect and a skin condition improving effect. In addition, the composition containing probiotics and vitamin C as active ingredients according to the present invention can more effectively induce antioxidant effects to activate energy metabolism in vivo, thereby exhibiting a significant synergistic effect on weight loss.
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公开(公告)号：US11920124B2
公开(公告)日：2024-03-05
申请号：US16839289
申请日：2020-04-03
发明人： Myung Jun Chung
IPC分类号： C12N1/20 , A23J3/34 , A23L3/44 , A23L33/125 , A23L33/135 , A23L33/18 , A23L33/185 , A23L33/19 , A23P20/10 , C12N1/04 , C12P21/06
CPC分类号： C12N1/20 , A23J3/344 , A23J3/346 , A23L3/44 , A23L33/125 , A23L33/135 , A23L33/18 , A23L33/185 , A23L33/19 , A23P20/10 , C12N1/04 , C12P21/06 , A23V2002/00 , A23V2400/113 , A23V2400/249 , A23V2400/519
摘要： The present disclosure relates to a method of producing lactic acid bacteria dual-coated with protein and polysaccharide by using a protein hydrolysate, and lactic acid bacteria having a dual coating, produced by the method. The lactic acid bacteria having a dual coating of protein and polysaccharide, produced according to the present disclosure, have very excellent dry-freezing viability, acid resistance and bile resistance. Accordingly, the lactic acid bacteria having a dual coating of protein and polysaccharide according to the present disclosure will be very useful for the production of fermented milk, processed milk, fermented soy products, processed foods, functional beverages, functional foods, common foods, etc.
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公开(公告)号：US11298385B2
公开(公告)日：2022-04-12
申请号：US16471940
申请日：2018-10-16
发明人： Myung Jun Chung
IPC分类号： A01N63/00 , A61K39/00 , A61K39/02 , C07H21/02 , A61K35/747 , C07K14/47 , C12N1/20 , C12N15/74 , C12N15/62 , A61K38/16 , A61K35/745 , A61K35/744 , C12R1/23 , C12R1/24 , C12R1/245 , A61K38/00 , A61K35/74
摘要： The present invention relates to a microorganism for drug delivery, which has been transformed with a gene construct comprising a therapeutically active peptide, which can be delivered safely into the intestines through oral administration, and which can express and secrete the therapeutic peptide in the gastrointestinal tract, and also relates to a pharmaceutical composition for prevention or treatment of gastrointestinal disease, which includes the same. The present invention is directed to a lactic acid bacteria drug delivery system capable of overexpressing and secreting a lactic acid bacteria-derived anticancer protein, which is developed by introducing the anticancer protein into a lactic acid bacteria expression and secretion system. It is expected that the lactic acid bacteria drug delivery system will be widely used as a natural protein therapeutic agent against gastrointestinal disease in the medical field.
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公开(公告)号：US20210207077A1
公开(公告)日：2021-07-08
申请号：US17108558
申请日：2020-12-01
发明人： Myung Jun Chung
IPC分类号： C12N1/20
摘要： The present disclosure relates to a composition for promoting the growth of lactic acid bacteria comprising growth factors, and more particularly, to a composition for promoting the growth of lactic acid bacteria comprising growth factors, the composition being capable of efficiently promoting the growth of various lactic acid bacteria strains.
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