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    Directional headlamp assembly
    1.
    发明授权
    Directional headlamp assembly 有权

    公开(公告)号：US11440460B1

    公开(公告)日：2022-09-13

    申请号：US17361481

    申请日：2021-06-29

    申请人： Brian Spencer

    发明人： Brian Spencer

    IPC分类号： B60Q1/076 ,  F21S41/657 ,  B60Q1/00

    摘要： A directional headlamp assembly for independently directing light from a pair of headlamps includes a pair of headlamp modules and a controller. Each headlamp module replaces a respective headlamp of a pair of existing headlamps of a vehicle. The headlamp module comprises a first housing, which insertable of into an opening created upon removal of the respective headlamp, so that the first housing is engaged to the vehicle. A bulb is pivotally engaged to a front of the first housing. An actuator is engaged to and positioned in the first housing. The actuator is operationally engaged to the bulb. The controller is mountable within a passenger compartment of the vehicle so that it is accessible to a driver of the vehicle. The controller is independently and operationally engaged to each of the actuators and thus is positioned to selectively actuate each actuator to direct light emitted by an associated bulb.

    Method and System for Grouping Buyers Based on Common Interests
    3.
    发明申请
    Method and System for Grouping Buyers Based on Common Interests 审中-公开
    基于共同利益的买方分组方法与制度

    公开(公告)号：US20100180232A1

    公开(公告)日：2010-07-15

    申请号：US12687097

    申请日：2010-01-13

    申请人： David John Honan ,  Kenneth Joseph Hynes, II ,  Brian Spencer Campbell

    发明人： David John Honan ,  Kenneth Joseph Hynes, II ,  Brian Spencer Campbell

    IPC分类号： G06F3/048

    CPC分类号： G06Q30/02

    摘要： Described herein are embodiments for identifying and grouping users of a system based on common interests and/or purchasing goals. In embodiments, one or more items of interest of a user are determined based on user input. A group is formed based on the on the one or more items of interest to the first user. At least a second user is identified based in part on at least one predetermined criterion and based in part on the second user having at least one or more items of interest corresponding to the one or more items of interest of the first user and the one or more items upon which the group was formed. Once the group is formed, the second user is automatically notified of the formation of the group. A third user is identified based on at least a second one of a predetermined criterion and the third user is given access to the group.

    摘要翻译： 这里描述了用于基于共同兴趣和/或购买目标来识别和分组系统的用户的实施例。 在实施例中，基于用户输入来确定用户感兴趣的一个或多个项目。 基于第一用户感兴趣的一个或多个项目形成组。 基于至少一个预定标准部分地识别至少第二用户，并且部分地基于第二用户具有与第一用户的一个或多个兴趣项目相对应的至少一个或多个兴趣项目， 更多的项目组成员组成。 一旦组成了，第二个用户被自动通知组的形成。 基于预定标准中的至少第二个标识来识别第三用户，并且允许第三用户访问该组。

    Dynamic objects with property slot definition and runtime mechanisms
    4.
    发明授权
    Dynamic objects with property slot definition and runtime mechanisms 有权
    具有属性插槽定义和运行时机制的动态对象

    公开(公告)号：US07225426B2

    公开(公告)日：2007-05-29

    申请号：US10368084

    申请日：2003-02-18

    申请人： Brian Spencer Frank ,  John W. Sublett

    发明人： Brian Spencer Frank ,  John W. Sublett

    IPC分类号： G06F9/44

    CPC分类号： G06F17/3089 ,  G06F8/34 ,  G06F8/36 ,  G06F9/451 ,  G06F17/30905

    摘要： A component based software program, where each component is based on a component-type. Component-types are created from base classes comprising slot definitions. The slot definitions are identified and stored in a component-type object. One or more components of the component-type are created, each comprising a reference, to a component-type object and a slotmap having storage locations for values associated with property slots definitions, in the component-type object. Values for property slots are entered into components by being placed in the storage locations. Also disclosed is a method for automatically designating unique names to components. One root component is created. Further non-root components are placed within the root component or within other components, so that all components form a tree structure. A component is assigned a unique identification string, comprising a sequential list of all of the component's ancestors and the component's name.

    摘要翻译： 基于组件的软件程序，其中每个组件基于组件类型。 组件类型是从包含插槽定义的基类创建的。 槽定义被识别并存储在组件类型对象中。 在组件类型对象中，创建组件类型的一个或多个组件，每个组件包括参考，组件类型对象和具有与属性槽定义相关联的值的存储位置的时隙映射。 通过放置在存储位置将属性插槽的值输入到组件中。 还公开了一种用于自动指定组件的唯一名称的方法。 创建一个根组件。 其他非根组件放置在根组件内或其他组件中，以便所有组件形成树结构。 为一个组件分配一个唯一的标识字符串，包括所有组件的祖先和组件名称的顺序列表。

    Interface
    5.
    发明授权
    Interface 有权
    接口

    公开(公告)号：US07158974B2

    公开(公告)日：2007-01-02

    申请号：US10395316

    申请日：2003-03-24

    申请人： Michael John Williams ,  Jonathan Richard Thorpe ,  Mark John McGrath ,  Matthew Brian Spencer ,  Paul Edward Prayle ,  John Edward Hodgkins

    发明人： Michael John Williams ,  Jonathan Richard Thorpe ,  Mark John McGrath ,  Matthew Brian Spencer ,  Paul Edward Prayle ,  John Edward Hodgkins

    IPC分类号： G06F17/30

    CPC分类号： G11B27/031 ,  G11B27/11 ,  G11B27/322 ,  G11B27/326 ,  G11B2220/2516 ,  G11B2220/455 ,  G11B2220/90 ,  Y10S707/914 ,  Y10S707/916 ,  Y10S707/99931

    摘要： An application programmer's interface provides a facility for accessing metadata describing the content or attributes of information material. The application programmer's interface comprises a signalling protocol processor operable to receive a metadata string which includes a resource identifier providing an address of a metadata resource, and a file transfer processor operable to provide access to the metadata resource in accordance with a request from the application program. The signalling protocol processor provides an efficient facility for communicating the metadata string. The metadata string may be in the form of a mark-up language such as XML. The metadata resource may be for example a proxy version of the information material, such as a video proxy if the information material is video. Accordingly, the file transfer processor is arranged to provide efficient access to the video proxy using the address provided with metadata string. The address may be a Uniform Resource Identifier address allowing access to the resource from any network linked via the World Wide Web. The application programmer's interface therefore provides a standard interface format for making metadata and metadata resources available to application programs.

    摘要翻译： 应用程序员界面提供了访问描述信息资料的内容或属性的元数据的功能。 应用程序员接口包括信令协议处理器，可操作用于接收包括提供元数据资源的地址的资源标识符的元数据串，以及文件传输处理器，可操作以根据应用程序的请求提供对元数据资源的访问 。 信令协议处理器提供用于传送元数据字符串的有效设施。 元数据字符串可以是诸如XML的标记语言的形式。 元数据资源可以是例如信息资料的代理版本，例如视频代理，如果信息资料是视频。 因此，文件传输处理器被设置为使用提供有元数据字符串的地址来提供对视频代理的有效访问。 地址可以是统一资源标识符地址，允许从通过万维网链接的任何网络访问资源。 因此，应用程序员的界面提供了一种用于使元数据和元数据资源可用于应用程序的标准接口格式。

    Compounds for reversing and inhibiting protein aggregation, and methods for making and using them
    9.
    发明授权
    Compounds for reversing and inhibiting protein aggregation, and methods for making and using them 有权
    用于逆转和抑制蛋白质聚集的化合物，以及制备和使用它们的方法

    公开(公告)号：US08946165B2

    公开(公告)日：2015-02-03

    申请号：US13119400

    申请日：2009-09-29

    申请人： Eliezer Masliah ,  Brian Spencer ,  Edward Rockenstein ,  Robert Marr

    发明人： Eliezer Masliah ,  Brian Spencer ,  Edward Rockenstein ,  Robert Marr

    IPC分类号： A61K38/00 ,  C07K14/47 ,  C07K19/00

    CPC分类号： C07K14/4711 ,  A61K38/00 ,  C07K19/00

    摘要： The invention provides compositions for increasing the clearance of protein aggregates, and pharmaceutical compositions comprising them, and methods for making and using them, including methods for accelerating protein aggregate clearance in the CNS, e.g., for treating diseases that are characterized by protein aggregation—including some degenerative neurological diseases such as Parkinson's disease. In one aspect, the compositions of the invention specifically target synuclein, beta-amyloid and/or tau protein aggregates, and the methods of the invention can be used to specifically prevent, reverse, slow or inhibit synuclein, beta-amyloid and/or tau protein aggregation. In alternative embodiments, the compositions and methods of the invention, are used to treat, prevent, reverse (partially or completely) or ameliorate (including slowing the progression of) degenerative neurological diseases related to or caused by protein aggregation, e.g., synuclein, beta-amyloid and/or tau protein aggregation. In one aspect, compositions and methods of this invention are used to treat, prevent or ameliorate (including slowing the progression of) Parkinson's disease, fronto-temporal dementia (FTD), Alzheimer's Disease (AD), Lewy body disease (LBD) and Multiple system atrophy (MSA).

    摘要翻译： 本发明提供了用于增加蛋白质聚集体清除率的组合物，以及包含它们的药物组合物，以及用于制备和使用它们的方法，包括用于加速CNS中的蛋白质聚集体清除的方法，例如用于治疗以蛋白质聚集为特征的疾病 一些退行性神经系统疾病如帕金森病。 在一个方面，本发明的组合物特异性靶向突触核蛋白，β-淀粉样蛋白和/或tau蛋白聚集体，并且本发明的方法可用于特异性地预防，逆转，减缓或抑制突触核蛋白，β-淀粉样蛋白和/或tau 蛋白质聚集。 在替代实施方案中，本发明的组合物和方法用于治疗，预防，逆转（部分或完全）或改善（包括减缓进展）与蛋白质聚集相关或由其引起的退行性神经疾病，例如突触核蛋白，β - 淀粉样蛋白和/或tau蛋白聚集。 一方面，本发明的组合物和方法用于治疗，预防或改善（包括减缓帕金森氏病，颞叶性痴呆（FTD），阿尔茨海默病（AD），路易体病（LBD）和多发性硬化症 系统萎缩（MSA）。

    SYSTEM FOR GENERATING ALARMS BASED ON ALARM PATTERNS
    10.
    发明申请
    SYSTEM FOR GENERATING ALARMS BASED ON ALARM PATTERNS 有权
    基于报警模式生成报警的系统

    公开(公告)号：US20120286955A1

    公开(公告)日：2012-11-15

    申请号：US13450942

    申请日：2012-04-19

    申请人： James P. Welch ,  Brian Spencer Long

    发明人： James P. Welch ,  Brian Spencer Long

    IPC分类号： G08B21/02

    CPC分类号： A61B5/746 ,  A61B5/0205 ,  A61B5/02455 ,  A61B5/14551 ,  G08B21/0453 ,  G16H40/63 ,  G16H40/67

    摘要： An alarm system can include one or more processors. Such processors can receive physiological parameter data associated with a patient. The one or more processors can also select an alarm pattern based at least in part on an indicator of an attribute of the patient. The alarm pattern can include a plurality of different thresholds and corresponding periods of time. Further, the one or more processors can generate an alarm when a value associated with the physiological parameter data satisfies at least one threshold of the plurality of thresholds for the period of time corresponding to the at least one threshold.

    摘要翻译： 报警系统可以包括一个或多个处理器。 这样的处理器可以接收与患者相关联的生理参数数据。 所述一个或多个处理器还可以至少部分地基于患者的属性的指示符来选择警报模式。 警报模式可以包括多个不同的阈值和相应的时间段。 此外，当与生理参数数据相关联的值满足对应于至少一个阈值的时间段中的多个阈值的至少一个阈值时，一个或多个处理器可以产生警报。