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公开(公告)号:US20240058807A1
公开(公告)日:2024-02-22
申请号:US18498220
申请日:2023-10-31
CPC分类号: B01L3/50215 , B01L3/5021 , B01L3/50825 , G01N1/4077 , C12M45/05 , B04B5/0414 , C12Q1/24 , B01L3/0296 , G01N1/2035 , B01L3/5082 , B01L2400/0478 , B01L2400/0633 , B01L2300/0681 , B01L2400/0683 , G01N2001/4083 , B01L2200/0689 , B01L2300/0672 , B04B2011/046
摘要: A separation container for extracting a portion of a sample for use or testing and method for preparing samples for downstream use or testing are provided. The separation container may include a body defining an internal chamber. The body may define an opening, and the body may be configured to receive the sample within the internal chamber. The separation container may further include a seal disposed across the opening, such that the seal may be configured to seal the opening of the body, and a plunger movably disposed at least partially inside the internal chamber. The plunger may be configured to be actuated to open the seal and express the portion of the sample.
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2.
公开(公告)号:US11673141B2
公开(公告)日:2023-06-13
申请号:US17474544
申请日:2021-09-14
申请人: bioMerieux, Inc.
IPC分类号: G01N21/01 , G01N15/06 , G01N21/51 , G01N21/88 , G01N21/93 , B01L3/00 , G01N21/59 , G01N21/47 , G01N1/10 , G01N21/27 , G01N33/487 , G01N21/03
CPC分类号: B01L3/50853 , G01N1/10 , G01N15/06 , G01N21/01 , G01N21/0303 , G01N21/274 , G01N21/4738 , G01N21/4785 , G01N21/51 , G01N21/5907 , G01N21/8806 , G01N21/93 , G01N33/487 , G01N33/48735 , B01L2200/14 , B01L2300/0654 , B01L2300/0803 , B01L2300/12 , G01N21/474 , G01N2015/0693 , G01N2021/0168 , G01N2021/0389 , G01N2021/4769 , G01N2021/598 , G01N2201/126 , G01N2201/12707
摘要: A method, computer program product, and apparatus are provided for controlling components of a detection device. The device may detect turbidity of liquid with sensors such as a density sensor and/or nephelometric sensor. A light modulation pattern may reduce or eliminate interference in sensor readings. Readings may be performed during off cycles of an illumination light to reduce interference but to provide improved visibility of a tube. Dark and light sensor readings may be performed with an emitter respectively off or on to account for ambient light in subsequent readings. Readings from the density sensor and/or nephelometric sensor may be used to calculate McFarland values. The device may be zeroed based on an emitter level that results in a sensor reading satisfying a predetermined criterion.
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公开(公告)号:US11406981B2
公开(公告)日:2022-08-09
申请号:US16546756
申请日:2019-08-21
申请人: bioMerieux, Inc.
摘要: Automated test instruments electronically determine and/or obtain cell availability of cells of a holding structure in an incubated test chamber and for each of a plurality of open and available cells and electronically identify neighboring cells, electronically determining whether each of the identified neighboring cells are occupied or empty and, if occupied, electronically evaluating at least one of a test status or a time from load of a specimen container held therein. The instruments then electronically rank each of the plurality of open and available cells based at least in part on whether the identified neighboring cells are occupied or empty and the at least one of test status or time from load of the occupied cells of the identified neighboring cells. The loading mechanism is then directed to load an incoming specimen container into a selected one of the open and available cells based on the ranking.
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公开(公告)号:US20220203355A1
公开(公告)日:2022-06-30
申请号:US17694020
申请日:2022-03-14
摘要: Systems, methods, and apparatus are provided for evacuating and for filling an array at the point of use.
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公开(公告)号:US11305273B2
公开(公告)日:2022-04-19
申请号:US16046270
申请日:2018-07-26
IPC分类号: B01L3/00 , G01N1/40 , B01L3/02 , B04B5/04 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/20 , B04B11/04
摘要: A separation container for extracting a portion of a sample for use or testing and method for preparing samples for downstream use or testing are provided. The separation container may include a body defining an internal chamber. The body may define an opening, and the body may be configured to receive the sample within the internal chamber. The separation container may further include a seal disposed across the opening, such that the seal may be configured to seal the opening of the body, and a plunger movably disposed at least partially inside the internal chamber. The plunger may be configured to be actuated to open the seal and express the portion of the sample.
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公开(公告)号:US11285487B2
公开(公告)日:2022-03-29
申请号:US15958777
申请日:2018-04-20
申请人: bioMerieux, Inc.
IPC分类号: G01N21/01 , B01L3/00 , G01N21/59 , G01N21/47 , G01N1/10 , G01N21/27 , G01N33/487 , G01N21/03 , G01N15/06 , G01N21/51 , G01N21/88 , G01N21/93
摘要: Apparatuses and associated methods of manufacturing are described that provide a tip resistant optical testing instrument configured to rest on a surface. The optical testing instrument includes a shell defining a cavity for receiving a sample tube. The shell includes a bottom shell surface, wherein the bottom shell surface defines at least one support element, wherein the at least one support element is configured to engage the surface to support the optical testing instrument in a testing position, and a translational surface configured to engage the surface to support the optical testing instrument in an angled position. In an instance in which the optical testing instrument tilts from the testing position to the angled position, the translational surface is configured to engage the surface contacting the translational surface to prevent the optical testing instrument from tipping further and allow the optical testing instrument to return to the testing position.
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公开(公告)号:US20210370284A1
公开(公告)日:2021-12-02
申请号:US17356052
申请日:2021-06-23
摘要: A separation container for extracting a portion of a sample for use or testing and method for preparing samples for downstream use or testing are provided. The separation container may include a body defining an internal chamber. The body may define an opening, and the body may be configured to receive the sample within the internal chamber. The separation container may further include a seal disposed across the opening, such that the seal may be configured to seal the opening of the body, and a plunger movably disposed at least partially inside the internal chamber. The plunger may be configured to be actuated to open the seal and express the portion of the sample.
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公开(公告)号:US20210074535A1
公开(公告)日:2021-03-11
申请号:US16950992
申请日:2020-11-18
申请人: bioMerieux, Inc.
发明人: Jared Bullock , Scott Collins , Mark Talmer
摘要: Load lock assemblies for a sample analysis system, such as a mass spectrometry system, include a load lock chamber having longitudinally opposing first and second end portions and a through channel, a door coupled to the second end portion, and a seal assembly coupled to the first end portion. The seal assembly includes a rigid seal housing member coupled to a housing of the load lock chamber. The rigid seal housing member includes a port forming part of the first end portion of the through channel of the load lock chamber. The rigid seal housing member can include a self-centering cartridge and/or a flexure member coupled to the housing of the load lock chamber. Where used, the flexure member has an outer perimeter that extends above and below the rigid seal housing member and includes an aperture that is aligned with the port of the rigid seal housing member.
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10.
公开(公告)号:US20200061605A1
公开(公告)日:2020-02-27
申请号:US16546756
申请日:2019-08-21
申请人: bioMerieux, Inc.
摘要: Automated test instruments electronically determine and/or obtain cell availability of cells of a holding structure in an incubated test chamber and for each of a plurality of open and available cells and electronically identify neighboring cells, electronically determining whether each of the identified neighboring cells are occupied or empty and, if occupied, electronically evaluating at least one of a test status or a time from load of a specimen container held therein. The instruments then electronically rank each of the plurality of open and available cells based at least in part on whether the identified neighboring cells are occupied or empty and the at least one of test status or time from load of the occupied cells of the identified neighboring cells. The loading mechanism is then directed to load an incoming specimen container into a selected one of the open and available cells based on the ranking.
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