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    SYSTEM AND METHOD FOR FINE NEEDLE ASPIRATION
    1.
    发明申请
    SYSTEM AND METHOD FOR FINE NEEDLE ASPIRATION 审中-公开
    用于精细针刺的系统和方法

    公开(公告)号：US20150005662A1

    公开(公告)日：2015-01-01

    申请号：US14370850

    申请日：2013-01-22

    申请人： Robert Brik ,  Alexander Mark Lesman ,  Kevin Chen ,  Alex Joseph Neff Speltz ,  Jisoo Kim ,  Alexander Slocum ,  Sareh Parangi ,  William Clay Faquin

    发明人： Robert Brik ,  Alexander Mark Lesman ,  Kevin Chen ,  Alex Joseph Neff Speltz ,  Jisoo Kim ,  Alexander Slocum ,  Sareh Parangi ,  William Clay Faquin

    IPC分类号： A61B10/02

    CPC分类号： A61B10/0266 ,  A61B10/0283 ,  A61B2010/0216

    摘要： A system and method for fine needle aspiration includes a plurality of components. A device includes a body unit, a trigger unit, and at least one gear. The body unit is configured to hold a syringe, and the trigger unit is configured to laterally move relative to the body unit in order to extend and retract a plunger within the syringe. The at least one gear is configured to engage the syringe so that lateral movement of the trigger unit causes rotation of the syringe. A needle includes a distal tip with a vertical edge extending from a distal end to a proximal end, and a curved edge running from the distal end to the proximal end. A syringe kit includes a stylet connected to the plunger. The stylet includes an outer diameter equal to an inner diameter of the needle.

    摘要翻译： 用于细针抽吸的系统和方法包括多个部件。 一种装置包括主体单元，触发单元和至少一个齿轮。 身体单元被配置为保持注射器，并且触发器单元构造成相对于身体单元横向移动，以便在注射器内延伸和缩回柱塞。 所述至少一个齿轮构造成接合所述注射器，使得所述触发器单元的横向移动引起所述注射器的旋转。 针包括具有从远端延伸到近端的垂直边缘的远侧末端以及从远端延伸到近端的弯曲边缘。 注射器套件包括连接到柱塞的探针。 探针包括等于针的内径的外径。

    STEROID HORMONE DELIVERY SYSTEMS AND METHODS OF PREPARING THE SAME
    2.
    发明申请
    STEROID HORMONE DELIVERY SYSTEMS AND METHODS OF PREPARING THE SAME 审中-公开
    STEROID HORMONE输送系统及其制备方法

    公开(公告)号：US20130045271A1

    公开(公告)日：2013-02-21

    申请号：US13588731

    申请日：2012-08-17

    申请人： Eric Dadey ,  Alexander Mark Schobel

    发明人： Eric Dadey ,  Alexander Mark Schobel

    IPC分类号： A61K9/127 ,  A61P5/24 ,  A61K31/568

    CPC分类号： A61K9/1075 ,  A61K9/006 ,  A61K9/107 ,  A61K9/127 ,  A61K9/1271 ,  A61K9/1272 ,  A61K9/145 ,  A61K9/7007 ,  A61K31/568

    摘要： The present invention is directed to steroid hormone delivery systems and methods of preparing the same. In particular, the steroid hormone delivery systems provided include a primary construct having one or more hydrophobic steroid hormone esters in the form of a liposome, a lipid particle, a micelle, an emulsion or a niosome which is then formulated into a secondary construct for administration. Exemplary secondary constructs include a film for sublingual or buccal administration.

    摘要翻译： 本发明涉及类固醇激素递送系统及其制备方法。 特别地，所提供的类固醇激素递送系统包括具有一种或多种脂质体形式的疏水性类固醇激素酯的主要构建体，脂质颗粒，胶束，乳剂或组合物，然后将其配制成用于施用的二级结构 。 示例性的二级结构包括用于舌下或口腔给药的膜。

    Methods and systems for identifying manipulated articles
    6.
    发明授权
    Methods and systems for identifying manipulated articles 有权
    用于识别操纵物品的方法和系统

    公开(公告)号：US07302645B1

    公开(公告)日：2007-11-27

    申请号：US10732048

    申请日：2003-12-10

    申请人： Monika Henzinger ,  Alexander Mark Franz

    发明人： Monika Henzinger ,  Alexander Mark Franz

    IPC分类号： G06F15/00 ,  G06F13/00

    CPC分类号： G06F17/3071 ,  G06F17/30864

    摘要： Systems and methods that identify manipulated articles are described. In one embodiment, a search engine implements a method comprising determining at least one cluster comprising a plurality of articles, analyzing signals to determine an overall signal for the cluster, and determining if the articles are manipulated articles based at least in part on the overall signal.

    摘要翻译： 描述识别操纵物品的系统和方法。 在一个实施例中，搜索引擎实现一种方法，包括确定至少一个包含多个物品的群集，分析信号以确定群集的整体信号，以及至少部分地基于总体信号来确定物品是否被操纵物品 。

    Hydrotransformer
    7.
    发明申请
    Hydrotransformer 审中-公开

    公开(公告)号：US20060051223A1

    公开(公告)日：2006-03-09

    申请号：US10509990

    申请日：2003-04-10

    申请人： Alexander Mark ,  Rudolf Schaffer

    发明人： Alexander Mark ,  Rudolf Schaffer

    IPC分类号： F04B27/08 ,  A61M1/00

    CPC分类号： F04B1/20 ,  F04B1/32 ,  F04B1/328 ,  F04B9/10

    摘要： The invention is based on a hydraulic transformer having a housing and having an expeller part in which a plurality of expellers which bound a number of expeller spaces with variable volumes are guided, a cam part on which the expellers are supported, and a valving surface which has three kidney-shaped control slots, one of which is connected to a supply port, one to a working port and one to a reservoir tank port. The objective is to provide a hydraulic transformer in which complex setting of the transmission ratio is avoided. The aimed-at objective is achieved according to the invention in that the valving surface can be driven in rotation by means of a drive, and in that of the two components comprising the expeller part and cam element one component is essentially arranged fixedly with respect to the housing and the other component can move freely in terms of two rotational or translatory degrees of freedom within a limited range.

    摘要翻译： 本发明基于具有壳体并具有排出部分的液压变压器，其中结合了多个具有可变容积的排出器空间的多个驱动器被引导，其上支撑有驱出器的凸轮部分和阀表面， 具有三个肾形控制槽，其中一个连接到供油口，一个连接到工作端口，一个连接到储油箱端口。 目的是提供一种液压变压器，其中避免了传动比的复杂设定。 根据本发明实现了目标，其目的是通过驱动来驱动阀门的表面，并且在包括排出件和凸轮元件的两个部件中，一个部件基本相对于 壳体和另一个部件可以在有限的范围内的两个旋转或平移自由度方面自由移动。

    Process for forming tubular components
    8.
    发明授权
    Process for forming tubular components 失效
    用于形成管状部件的方法

    公开(公告)号：US06651477B2

    公开(公告)日：2003-11-25

    申请号：US09368775

    申请日：1999-08-05

    申请人： Peter Humphries ,  Alexander Mark Duff ,  Simon Jonathan Giles Griffiths

    发明人： Peter Humphries ,  Alexander Mark Duff ,  Simon Jonathan Giles Griffiths

    IPC分类号： B21D4102

    CPC分类号： B21D53/88 ,  B21D41/02 ,  B62D25/145

    摘要： A process of producing from an elongate tube a tubular structural component having a first longitudinal section integrally connected to a second longitudinal section, the second section being located at the end of the tube and being of a desired cross-sectional shape and size, the cross-sectional size of the second section being greater than that of the first section, the process including selecting a mandrel having a cross-sectional shape and size corresponding to the second section, relatively axially feeding said end of the tube over the mandrel in order to form said second section, the choice of the size of mandrel and the rate of feed and the axial pressure applied to said tube being controlled such that the wall thickness of the second section is on average at least 70 percent of the average wall thickness of the first wall section.

    摘要翻译： 一种从细长管制造的管状结构部件，其具有与第二纵向部分整体连接的第一纵向部分，第二部分位于管的端部并且具有期望的横截面形状和尺寸，十字形 所述第二部分的尺寸大于所述第一部分的尺寸，所述方法包括选择具有对应于所述第二部分的横截面形状和尺寸的心轴，将所述管的所述端部相对轴向地馈送在所述心轴上，以便于 形成所述第二部分，选择心轴的尺寸以及施加到所述管的进料速率和轴向压力被控制，使得第二部分的壁厚度平均为平均壁厚的至少70％ 第一个墙段。

    Radiolabelled bisphosphonates and method
    9.
    发明授权
    Radiolabelled bisphosphonates and method 失效
    放射性标记的双膦酸盐和方法

    公开(公告)号：US06534488B1

    公开(公告)日：2003-03-18

    申请号：US10031760

    申请日：2002-05-08

    申请人： Alexander Mark Gibson ,  Marivi Mendizabal ,  Richard Pither ,  Shirley Elizabeth Pullan ,  Vaughan Griffiths ,  Philip Duncanson

    发明人： Alexander Mark Gibson ,  Marivi Mendizabal ,  Richard Pither ,  Shirley Elizabeth Pullan ,  Vaughan Griffiths ,  Philip Duncanson

    IPC分类号： C07F938

    CPC分类号： C07B59/004 ,  C07F9/386 ,  C07F9/3873 ,  C07F9/409

    摘要： The present invention relates to 32P or 33P-labelled bisphosphonates as radiotherapeutic radiopharmaceuticals. The 32P- or 33P-labelled bisphosphonates, which are chemically identical to the unlabelled agent, are expected to target the lesion site in an identical manner, but also deliver a significant radiocytotoxic effect to the surrounding cells. This should result, given the favorable energetics of the &bgr; particle emission from the 33P nuclide, in a loss of proliferative capacity of cells associated with the tumor lesion. The relative stability and in vivo localisation of bisphosphonates makes them good candidates as 32P/33P delivery vehicles.

    摘要翻译： 本发明涉及作为放射治疗放射性药物的32P或33P标记的双膦酸盐。 与未标记试剂化学相同的32P或33P标记的双膦酸盐预期以相同的方式靶向病变部位，但也对周围细胞产生显着的放射性细胞毒性作用。 考虑到来自33P核素的β粒子发射的有利能量，与肿瘤病变相关的细胞的增殖能力丧失将导致这一点。 双膦酸盐的相对稳定性和体内定位使其成为32P / 33P递送载体的良好候选物。

    Hydroforming process
    10.
    发明授权
    Hydroforming process 有权
    液压成型工艺

    公开(公告)号：US6067831A

    公开(公告)日：2000-05-30

    申请号：US219051

    申请日：1998-12-23

    申请人： Peter Amborn ,  Alexander Mark Duff

    发明人： Peter Amborn ,  Alexander Mark Duff

    IPC分类号： B21D26/02 ,  B21D26/033 ,  B21D26/055

    CPC分类号： B21D26/033 ,  B21D26/055 ,  Y10S72/709 ,  Y10T29/49805

    摘要： A hydroforming process for forming a component from an elongate tubular blank comprised of a deformable metal, the process including placing the blank in a die and sealing opposed ends of the tubular blank, heating the blank to a predetermined deformation temperature which is greater than 350.degree. C. but less than the melting point of the metal, supplying a gas at a predetermined pressure to the interior of the sealed tubular blank to cause deformation of said tubular blank at predetermined regions by drawing/stretching of the metal.

    摘要翻译： 一种用于从由可变形金属组成的细长管状坯料形成部件的液压成型方法，该方法包括将坯料放置在模具中并密封管状坯料的相对端，将坯料加热到大于350°的预定变形温度 但小于金属的熔点，将预定压力的气体供应到密封管状坯料的内部，以通过金属的拉伸/拉伸使所述管状坯料在预定区域发生变形。