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公开(公告)号：US20120165929A1
公开(公告)日：2012-06-28
申请号：US13262539
申请日：2010-03-30
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2002/9522 , A61F2220/005 , A61F2230/005 , A61F2230/0054
摘要： A heart valve prosthesis comprising: a support structure comprising a framework deformable between an expanded state and a compressed state and vice versa; and a flow-control structure, supported by the support structure, for permitting blood flow in a first direction, and for restricting blood flow in a direction opposite to the first direction. At least one end of the support structure comprises a plurality of apexes of the framework. The support structure is collapsible into the compressed state by pulling on the apexes, to enable it to be drawn into a sheath having an inner radial dimension smaller than the radial dimension of the support structure in the expanded state.
摘要翻译： 一种心脏瓣膜假体，包括：支撑结构，包括在膨胀状态和压缩状态之间可变形的框架，反之亦然; 以及由所述支撑结构支撑的用于允许血液沿第一方向流动并且用于限制与所述第一方向相反的方向的血流的流量控制结构。 支撑结构的至少一端包括框架的多个顶点。 支撑结构通过拉动顶点而可压缩成压缩状态，以使其能够被拉伸成具有小于扩张状态下的支撑结构的径向尺寸的内部径向尺寸的护套。
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公开(公告)号：US08858631B2
公开(公告)日：2014-10-14
申请号：US13542202
申请日：2012-07-05
CPC分类号： A61F2/04 , A61F2/02 , A61F2002/046 , A61F2230/006 , A61F2250/0029 , A61L27/18 , A61L27/20 , A61L27/3679 , A61L27/3813 , A61L27/3834 , A61L27/3882 , A61L27/54 , A61L2300/252 , A61L2300/412 , A61L2300/414 , A61L2300/64 , A61L2400/12 , A61L2430/22 , C12N5/0663 , C12N2502/23 , C12N2533/40 , C08L75/04
摘要： Articles, compositions, and methods for growing tissues and organs using bioreactors, including rotating bioreactors, are provided. Synthetic scaffolds for growing artificial tissue and organ transplants are also provided.
摘要翻译： 提供了使用生物反应器（包括旋转生物反应器）生长组织和器官的制品，组合物和方法。 还提供用于生长人造组织和器官移植物的合成支架。
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公开(公告)号：US10357358B2
公开(公告)日：2019-07-23
申请号：US13262539
申请日：2010-03-30
摘要： A heart valve prosthesis comprising: a support structure comprising a framework deformable between an expanded state and a compressed state and vice versa; and a flow-control structure, supported by the support structure, for permitting blood flow in a first direction, and for restricting blood flow in a direction opposite to the first direction. At least one end of the support structure comprises a plurality of apexes of the framework. The support structure is collapsible into the compressed state by pulling on the apexes, to enable it to be drawn into a sheath having an inner radial dimension smaller than the radial dimension of the support structure in the expanded state.
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公开(公告)号：US20130142835A1
公开(公告)日：2013-06-06
申请号：US13542218
申请日：2012-07-05
CPC分类号： A61F2/04 , A61F2/02 , A61F2002/046 , A61F2230/006 , A61F2250/0029 , A61L27/18 , A61L27/20 , A61L27/3679 , A61L27/3813 , A61L27/3834 , A61L27/3882 , A61L27/54 , A61L2300/252 , A61L2300/412 , A61L2300/414 , A61L2300/64 , A61L2400/12 , A61L2430/22 , C12N5/0663 , C12N2502/23 , C12N2533/40 , C08L75/04
摘要： Articles, compositions, and methods for growing tissues and organs using bioreactors, including rotating bioreactors, are provided. Synthetic scaffolds for growing artificial tissue and organ transplants are also provided.
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公开(公告)号：US20130066438A1
公开(公告)日：2013-03-14
申请号：US13542202
申请日：2012-07-05
IPC分类号： A61F2/02
CPC分类号： A61F2/04 , A61F2/02 , A61F2002/046 , A61F2230/006 , A61F2250/0029 , A61L27/18 , A61L27/20 , A61L27/3679 , A61L27/3813 , A61L27/3834 , A61L27/3882 , A61L27/54 , A61L2300/252 , A61L2300/412 , A61L2300/414 , A61L2300/64 , A61L2400/12 , A61L2430/22 , C12N5/0663 , C12N2502/23 , C12N2533/40 , C08L75/04
摘要： Articles, compositions, and methods for growing tissues and organs using bioreactors, including rotating bioreactors, are provided. Synthetic scaffolds for growing artificial tissue and organ transplants are also provided.
摘要翻译： 提供了使用生物反应器（包括旋转生物反应器）生长组织和器官的制品，组合物和方法。 还提供用于生长人造组织和器官移植物的合成支架。
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