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    Device for multi-modal treatment of vascular lesions
    1.
    发明授权
    Device for multi-modal treatment of vascular lesions 失效
    用于多模式治疗血管病变的装置

    公开(公告)号：US07294137B2

    公开(公告)日：2007-11-13

    申请号：US10109112

    申请日：2002-03-27

    申请人： Patrick Rivelli, Jr. ,  Alec Piplani ,  Sean Donahue ,  Arani Bose ,  Alexander Leynov

    发明人： Patrick Rivelli, Jr. ,  Alec Piplani ,  Sean Donahue ,  Arani Bose ,  Alexander Leynov

    IPC分类号： A61M29/00

    CPC分类号： A61M39/105 ,  A61F2/966 ,  A61M2025/0004 ,  A61M2025/0042

    摘要： A device and method for permitting multi-modal treatment of vascular lesions are disclosed. The device includes an outer delivery catheter, an inner delivery catheter, and a guidewire. The catheter is designed to pass through the inner lumen of the outer delivery catheter, and the guidewire is designed to pass through the inner lumen of the inner delivery catheter. A stent may be loaded inside the outer delivery catheter, with the distal tip of the inner delivery catheter abutting against the proximal end of the self-expanding stent, for pushing the stent distally through the outer delivery catheter.

    摘要翻译： 公开了允许血管病变多模态治疗的装置和方法。 该装置包括外部输送导管，内部输送导管和导丝。 导管被设计成穿过外部输送导管的内腔，并且导丝被设计成穿过内部输送导管的内腔。 支架可以装载在外部输送导管内部，其中内部输送导管的远侧末端抵靠自扩张支架的近端，用于将支架向远侧推动通过外部输送导管。

    INTRALUMINAL GRAFTING SYSTEM
    4.
    发明申请
    INTRALUMINAL GRAFTING SYSTEM 审中-公开
    腹腔牵引系统

    公开(公告)号：US20070179591A1

    公开(公告)日：2007-08-02

    申请号：US11625755

    申请日：2007-01-22

    申请人： Steven Baker ,  Dinah Quiachon ,  Alec Piplani ,  Wesley Sterman ,  Ronald Williams

    发明人： Steven Baker ,  Dinah Quiachon ,  Alec Piplani ,  Wesley Sterman ,  Ronald Williams

    IPC分类号： A61F2/06

    CPC分类号： A61F2/07 ,  A61B17/11 ,  A61F2/04 ,  A61F2/82 ,  A61F2/848 ,  A61F2/89 ,  A61F2/958 ,  A61F2002/075 ,  A61F2002/3008 ,  A61F2002/30451 ,  A61F2002/8486 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2250/0098 ,  A61M25/10 ,  A61M2025/1068

    摘要： An intraluminal grafting system having a delivery catheter comprising a flexible elongate tubular member having proximal and distal extremities and a capsule mounted on the distal extremity of the tubular member and including a graft disposed within the capsule. The graft is comprised of a tubular body configured to be secured to a blood vessel by a self expanding attachment system. The attachment system comprises a generally sinusoidal wire frame having apices which extend longitudinally outward from the end of the tubular body apices which are secured within the tubular body. Both the protruding apices and the base apices are formed with helices which bias the attachment system radially outward. The attachment system further includes a plurality of lumen piercing members that are oriented in a responsive relationship to the radially outward bias of the attachment system. Furthermore, the graft may be configured with a plurality of synthetic fiber tufts secured to the outer surface of the tubular body to facilitate sealing the graft within the vessel. The graft may also include a plurality of crimps formed in the tubular body of the graft.

    摘要翻译： 一种管腔内接枝系统，其具有递送导管，其包括具有近端和远端的柔性细长管状构件和安装在管状构件的远端上的胶囊，并且包括设置在囊内的移植物。 移植物由构造成通过自扩张附接系统固定到血管的管状体构成。 连接系统包括大致正弦的线框架，其具有从管状体顶点的端部纵向向外延伸的顶点，其固定在管状体内。 突出的顶点和基部顶点均形成有将附件系统径向向外偏置的螺旋。 附接系统还包括多个内腔穿刺构件，其以与附接系统的径向向外偏置成反应的关系定向。 此外，移植物可以配置有固定到管状体的外表面的多个合成纤维束，以便于将移植物密封在血管内。 移植物还可以包括形成在移植物的管状体中的多个卷曲。

    Neurovascular stent and method
    5.
    发明授权
    Neurovascular stent and method 有权
    神经血管支架和方法

    公开(公告)号：US07037330B1

    公开(公告)日：2006-05-02

    申请号：US09715878

    申请日：2000-11-17

    申请人： Patrick Rivelli, Jr. ,  Alec Piplani ,  Sean Donahue ,  Alexander Leynov

    发明人： Patrick Rivelli, Jr. ,  Alec Piplani ,  Sean Donahue ,  Alexander Leynov

    IPC分类号： A61F2/06

    CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/823 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2230/0054

    摘要： A stent designed for catheter delivery to a target neurovascular site via a tortuous path, in a contracted state, and deployment at the target site, in an expanded state, is disclosed. The stent includes a plurality of expandable tubular members, where member is composed of a continuous wire element forming a plurality of wave segments, and segment contains a pair of opposite looped peaks having a wave shape such that the distance between adjacent sides of a wave, on proceeding from a peak toward opposite peaks, increases monotonically with an inflection point therebetween. The expandable tubular members are joined through adjacent peaks by axial connectors Radial expansion of the stent from a contracted to expanded state is accommodated by movement of adjacent wave-segment peaks away from one another, without significant change in the axial dimension of the stent. Also disclosed are a system incorporating the stent, and a method of treating a neurovascular abnormality.

    摘要翻译： 公开了一种支架，其设计用于在扩张状态下通过弯曲路径，处于收缩状态和目标部位的展开将导管递送至目标神经血管部位。 支架包括多个可扩张的管状构件，其中构件由形成多个波段的连续线元件组成，并且段包含一对具有波形的相对环形峰，使得波的相邻边之间的距离， 在从峰值向相反的峰值进行的同时，它们之间的拐点单调增加。 可扩张的管状构件通过轴向连接通过相邻的峰连接。支架从收缩状态到膨胀状态的径向膨胀通过相邻波段峰值相互远离的运动来适应，而支架的轴向尺寸没有显着变化。 还公开了并入支架的系统和治疗神经血管异常的方法。

    NEUROVASCULAR STENT AND METHOD
    6.
    发明申请
    NEUROVASCULAR STENT AND METHOD 审中-公开
    神经病理学和方法

    公开(公告)号：US20100222864A1

    公开(公告)日：2010-09-02

    申请号：US12752847

    申请日：2010-04-01

    申请人： Patrick Rivelli, JR. ,  Alec Piplani ,  Sean Donahue ,  Alexander Leynov

    发明人： Patrick Rivelli, JR. ,  Alec Piplani ,  Sean Donahue ,  Alexander Leynov

    IPC分类号： A61F2/84 ,  A61F2/82

    CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/823 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2230/0054

    摘要： A stent designed for catheter delivery to a target neurovascular site via a tortuous path, in a contracted state, and deployment at the target site, in an expanded state, is disclosed. The stent includes a plurality of expandable tubular members, where member is composed of a continuous wire element forming a plurality of wave segments, and segment contains a pair of opposite looped peaks having a wave shape such that the distance between adjacent sides of a wave, on proceeding from a peak toward opposite peaks, increases monotonically with an inflection point therebetween. The expandable tubular members are joined through adjacent peaks by axial connectors. Radial expansion of the stent from a contracted to expanded state is accommodated by movement of adjacent wave-segment peaks away from one another, without significant change in the axial dimension of the stent. Also disclosed are a system incorporating the stent, and a method of treating a neurovascular abnormality.

    摘要翻译： 公开了一种支架，其设计用于在扩张状态下通过弯曲路径，处于收缩状态和目标部位的展开将导管递送至目标神经血管部位。 支架包括多个可扩张的管状构件，其中构件由形成多个波段的连续线元件组成，并且段包含一对具有波形的相对环形峰，使得波的相邻边之间的距离， 在从峰值向相反的峰值进行的同时，它们之间的拐点单调增加。 可膨胀的管状构件通过轴向连接器通过相邻的峰连接。 支架从收缩状态到扩张状态的径向膨胀通过相邻波段峰值相互远离的运动来适应，而支架的轴向尺寸没有显着变化。 还公开了并入支架的系统和治疗神经血管异常的方法。

    Neurovascular stent and method
    7.
    发明授权
    Neurovascular stent and method 有权
    神经血管支架和方法

    公开(公告)号：US07695507B2

    公开(公告)日：2010-04-13

    申请号：US11393200

    申请日：2006-03-30

    申请人： Patrick Rivelli, Jr. ,  Alec Piplani ,  Sean Donahue ,  Alexander Leynov

    发明人： Patrick Rivelli, Jr. ,  Alec Piplani ,  Sean Donahue ,  Alexander Leynov

    IPC分类号： A61F2/06

    CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/823 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2230/0054

    摘要： A stent designed for catheter delivery to a target neurovascular site via a tortuous path, in a contracted state, and deployment at the target site, in an expanded state, is disclosed. The stent includes a plurality of expandable tubular members, where member is composed of a continuous wire element forming a plurality of wave segments, and segment contains a pair of opposite looped peaks having a wave shape such that the distance between adjacent sides of a wave, on proceeding from a peak toward opposite peaks, increases monotonically with an inflection point therebetween. The expandable tubular members are joined through adjacent peaks by axial connectors. Radial expansion of the stent from a contracted to expanded state is accommodated by movement of adjacent wave-segment peaks away from one another, without significant change in the axial dimension of the stent. Also disclosed are a system incorporating the stent, and a method of treating a neurovascular abnormality.

    摘要翻译： 公开了一种支架，其设计用于在扩张状态下通过弯曲路径，处于收缩状态和目标部位的展开将导管递送至目标神经血管部位。 支架包括多个可扩张的管状构件，其中构件由形成多个波段的连续线元件组成，并且段包含一对具有波形的相对环形峰，使得波的相邻边之间的距离， 在从峰值向相反的峰值进行的同时，它们之间的拐点单调增加。 可膨胀的管状构件通过轴向连接器通过相邻的峰连接。 支架从收缩状态到扩张状态的径向膨胀通过相邻波段峰值相互远离的运动来适应，而支架的轴向尺寸没有显着变化。 还公开了并入支架的系统和治疗神经血管异常的方法。

    Intracorporeal Grasping Device
    8.
    发明申请
    Intracorporeal Grasping Device 审中-公开
    体内抓握装置

    公开(公告)号：US20080269774A1

    公开(公告)日：2008-10-30

    申请号：US11924369

    申请日：2007-10-25

    申请人： Adrian Garcia ,  Ting Tina Ye ,  Quang Q. Tran ,  Bart Bojanowski ,  Alec Piplani ,  Aaron Lee Berez

    发明人： Adrian Garcia ,  Ting Tina Ye ,  Quang Q. Tran ,  Bart Bojanowski ,  Alec Piplani ,  Aaron Lee Berez

    IPC分类号： A61B17/221

    CPC分类号： A61B17/221 ,  A61B2017/22034 ,  A61B2017/2212 ,  A61B2017/2215

    摘要： An intracorporeal grasping device includes a tubular member for entering a lumen of a human body and the tube member having a distal end portion. An elongated core member is disposed with the interior cavity of the tubular member for rotational or slidably movement within the tubular member and the elongated core member having a proximal end portion and a distal end portion. The elongated core member comprises a uniform diameter tube having some flexibility at the proximal end portion and greater flexibility while along a longitudinal axis in a direction towards the distal end portion; and a grasping configuration is provided for capturing an object (e.g., clot or debris) therein and the assembly may have a proximal end secured to the distal end of the elongated core member. The configuration has an expanded and contracted configuration, and distal sections configured to grasp an object. The grasping configuration may be formed by at least one movable jaw attached to the distal end portion of the elongated core member and a length portion of the distal end portion of the tube member. The grasping configuration may include unitarily formed plurality of movable jaws attached to the distal end portion of the elongated core member. Further, the grasping configuration may be formed by a plurality of loop members attached to the distal end portion of the elongated core member. Further, the grasping configuration may be formed by at least one spiral member having a distal tip for penetrating an object to be removed from a human body lumen. The device has the spiral member provided at the distal end portion of the elongated core member. The grasping configuration can be formed by at least one web member for retaining an object to be removed from a human body lumen, the web member being provided at the distal end portion of the elongated core member.

    摘要翻译： 体内抓握装置包括用于进入人体内腔的管状构件和具有远端部分的管构件。 细长的芯构件设置有管状构件的内部空腔，用于在管状构件内旋转或可滑动地移动，并且细长的芯构件具有近端部分和远端部分。 细长的芯构件包括均匀直径的管，其在近端部分具有一些柔性，并且在朝向远端部分的方向上沿着纵向轴线具有更大的柔性; 并且提供抓握构造用于捕获其中的物体（例如凝块或碎屑），并且组件可以具有固定到细长芯构件的远端的近端。 该配置具有扩展和收缩配置，并且远端部分配置为抓住对象。 夹持构造可以由附接到细长芯构件的远端部分的至少一个可动夹爪和管构件的远端部分的长度部分形成。 抓持构造可以包括连接到细长芯构件的远端部分的一体形成的多个可动爪。 此外，抓持构造可以由附接到细长芯构件的远端部的多个环构件形成。 此外，抓持构造可以由至少一个螺旋构件形成，所述至少一个螺旋构件具有用于穿透要从人体腔去除的物体的远端。 该装置具有设置在细长芯部件的远端部分的螺旋部件。 抓持构造可以由至少一个腹板构件形成，用于将要从人体腔移除的物体保持在该细长的芯构件的远端部。

    Neurovascular stent and method
    10.
    发明申请
    Neurovascular stent and method 有权
    神经血管支架和方法

    公开(公告)号：US20060224230A1

    公开(公告)日：2006-10-05

    申请号：US11393200

    申请日：2006-03-30

    申请人： Patrick Rivelli ,  Alec Piplani ,  Sean Donahue ,  Alexander Leynov

    发明人： Patrick Rivelli ,  Alec Piplani ,  Sean Donahue ,  Alexander Leynov

    IPC分类号： A61F2/06

    CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/823 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2230/0054

    摘要： A stent designed for catheter delivery to a target neurovascular site via a tortuous path, in a contracted state, and deployment at the target site, in an expanded state, is disclosed. The stent includes a plurality of expandable tubular members, where member is composed of a continuous wire element forming a plurality of wave segments, and segment contains a pair of opposite looped peaks having a wave shape such that the distance between adjacent sides of a wave, on proceeding from a peak toward opposite peaks, increases monotonically with an inflection point therebetween. The expandable tubular members are joined through adjacent peaks by axial connectors. Radial expansion of the stent from a contracted to expanded state is accommodated by movement of adjacent wave-segment peaks away from one another, without significant change in the axial dimension of the stent. Also disclosed are a system incorporating the stent, and a method of treating a neurovascular abnormality.

    摘要翻译： 公开了一种支架，其设计用于在扩张状态下通过弯曲路径，处于收缩状态和目标部位的展开将导管递送至目标神经血管部位。 支架包括多个可扩张的管状构件，其中构件由形成多个波段的连续线元件组成，并且段包含一对具有波形的相对环形峰，使得波的相邻边之间的距离， 在从峰值向相反的峰值进行的同时，它们之间的拐点单调增加。 可膨胀的管状构件通过轴向连接器通过相邻的峰连接。 支架从收缩状态到扩张状态的径向膨胀通过相邻波段峰值相互远离的运动来适应，而支架的轴向尺寸没有显着变化。 还公开了并入支架的系统和治疗神经血管异常的方法。