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公开(公告)号：US10099203B2
公开(公告)日：2018-10-16
申请号：US15552530
申请日：2016-02-22
IPC分类号： B01J20/22 , B01J20/30 , C07C51/41 , C30B29/54 , C07D233/58 , C07F1/08 , C07F3/06 , C07D213/79
摘要： A method for the preparation of a metal-organic compound is provided. This method comprises the steps of (a) providing at least one metal precursor, (b) providing at least one bridging organic ligand, and (c) exposing together the metal precursor and the ligand to liquid CO2 or supercritical CO2 as a reaction medium, thereby producing said metal-organic compound.
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公开(公告)号：US10092574B2
公开(公告)日：2018-10-09
申请号：US15024169
申请日：2013-09-25
IPC分类号： A61K31/55 , A61K31/5375 , A61K31/18 , A61K31/505 , A61K31/40 , A61K31/495 , A61K31/381 , A61K31/352 , A61K31/445 , A61K31/357 , A61K31/4453 , A61K31/4406 , A61K31/454 , A61K31/415 , A61K31/4155 , A61K31/4439 , A61K31/353
摘要： Compounds which inhibit the formation and/or accumulation of RNA foci, such as those due to polynucleotide repeats (e.g., trinucleotide repeats) are described herein. Also described herein are uses of such compounds, such as for the inhibition of the formation and accumulation such RNA foci, as well as for the treatment of polynucleotide repeat disorders (e.g., trinucleotide repeat disorders), such as myotonic dystrophy (e.g., DM1). Such compounds include compounds of formula 1, 1a, 1b, 2, 2a and (3) described herein.
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3.发明授权Compositions comprising a radiosensitizer and an anti-cancer agent and methods of uses thereof 有权包含放射增敏剂和抗癌剂的组合物及其使用方法公开(公告)号：US09302003B2
公开(公告)日：2016-04-05
申请号：US13259213
申请日：2010-04-26
申请人： Léon Sanche , Gabriel Charest
发明人： Léon Sanche , Gabriel Charest
CPC分类号： A61K41/0038 , A61K9/0019 , A61K9/1271 , A61K31/282 , A61K33/24 , A61K45/06 , Y10S977/773 , Y10S977/911 , A61K2300/00
摘要： A combination of an anti-cancer agent and a metal radiosensitizer potentiates the radiotherapy of cancer. Said anti-cancer agent is preferably cisplatin while the metal radiosensitizer is preferably gold nanoparticles. Both the anti-cancer agent and the metal radiosensitizer bind to DNA and potentiate the radiotherapy of cancer by synergistically increases the amount of double strand breaks induced by the radiation. The anti-cancer agent and the metal radiosensitizer may be encapsulated in liposomes.
摘要翻译： 抗癌剂和金属放射增敏剂的组合增强了癌症的放射治疗。 所述抗癌剂优选为顺铂，而金属放射增敏剂优选为金纳米颗粒。 抗癌剂和金属放射增敏剂都与DNA结合，并通过协同增加由辐射引起的双链断裂的量来增强癌症的放射治疗。 抗癌剂和金属放射增敏剂可以包封在脂质体中。
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公开(公告)号：US09281664B2
公开(公告)日：2016-03-08
申请号：US13659164
申请日：2012-10-24
发明人： Sylvain David , Annie Larouche , Jean Robichaud
CPC分类号： H02B1/014 , E04F19/08 , E04F19/086 , Y10T403/32451
摘要： An access door adjustable to an opening, comprising a frame adjustable to the width and the height of the opening; and a door panel, the frame comprising side members and corner members; each side member having a section adapted to receive an edge of the opening and comprising a first part adapted to lay flat on an outer surface of the edge of the opening and a second part extending within the opening and comprising engagement positions, the engagement positions being adapted to engage the corner members between a maximum length for each side of the frame by using outermost engagement positions and a minimum length for each side of the frame, depending on the size of the opening, the frame receiving the door panel for closing the opening.
摘要翻译： 一个进入门可调节到一个开口，包括一个可调整到开口宽度和高度的框架; 和门板，所述框架包括侧构件和角构件; 每个侧构件具有适于容纳所述开口的边缘的部分，并且包括适于平坦地放置在所述开口的边缘的外表面上的第一部分和在所述开口内延伸并包括接合位置的第二部分，所述接合位置为 适于通过使用最外侧的接合位置和框架的每一侧的最小长度来使所述角部件接合在所述框架的每一侧的最大长度之间，这取决于所述开口的尺寸，所述框架接收用于封闭所述开口的门板 。
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公开(公告)号：US09272288B2
公开(公告)日：2016-03-01
申请号：US13801174
申请日：2013-03-13
摘要： A biomass conditioning system and method, the system comprising a chamber and an airflow loop, the chamber comprising a lower part adapted to receive biomass and comprising grinding elements, cutting elements and an air input, an airflow from the air input and rotation of the elements creating an uplifting; and an upper part comprising an inner chamber generally centered within an outer chamber, the outer chamber comprising a first outlet and the inner chamber comprising a second outlet; and a flange selectively connecting the lower part with the inner chamber and the lower part with the outer chamber; and the airflow loop comprising a source of input air in the lower part, a first exhaust connected to the first outlet and evacuating air and biomass particles from the inner chamber, and a second exhaust connected to the second outlet and evacuating mist and air from the outer chamber; in which the flange diverts, from the uplifting vortex and under action of a vacuum created between the air input and the second outlet, a water particle flow to the first outlet of the outer chamber and a biomass particles flow towards the inner chamber; light biomass particles being propelled up the inner chamber the second outlet.
摘要翻译： 一种生物质调节系统和方法，所述系统包括腔室和气流回路，所述腔室包括适于接纳生物质并包括研磨元件，切割元件和空气输入的下部，来自空气输入的气流和元件的旋转 创造一个令人振奋的 以及上部，其包括通常以外部腔室为中心的内部腔室，所述外部腔室包括第一出口，所述内部腔室包括第二出口; 以及凸缘，其选择性地将所述下部与所述内部腔室和所述下部部件与所述外部腔室连接; 并且所述气流回路包括下部的输入空气源，连接到所述第一出口的第一排气口以及从所述内部室排出空气和生物质颗粒;以及第二排气，其连接到所述第二出口并将雾和空气从所述第二出口排出 外室; 其中凸缘从提升涡流转移并且在空气输入和第二出口之间产生的真空作用下，水粒子流到外室的第一出口并且生物质颗粒流向内室; 光生物质颗粒被推向内室第二出口。
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7.发明授权Method and system for high power parametric amplification of ultra-broadband few-cycle laser pulses 有权超宽带几周期激光脉冲大功率参数放大方法与系统公开(公告)号：US09203208B2
公开(公告)日：2015-12-01
申请号：US14238792
申请日：2012-08-16
申请人： Bruno E. Schmidt , Francois Legare , Heide Ibrahim
发明人： Bruno E. Schmidt , Francois Legare , Heide Ibrahim
CPC分类号： H01S3/10038 , G02F1/39 , G02F2001/3507 , G02F2001/392 , H01S3/005 , H01S3/0057 , H01S3/2308 , H01S3/2383 , H03F7/00
摘要： A system and method for high power parametric amplification based on performing amplification in a frequency domain after time domain pulses are optically Fourier transformed, to overcome bandwidth limitations. In a nutshell, a first optical Fourier transformation of a seed spectrum is performed and parametric amplification is carried out in this spatially dispersed frequency plane. As a consequence, individual parts of the spectrum can be amplified using an optical amplification medium comprising a series of optical amplification units, such as different narrowband crystals, placed one next to each other. Each crystal is tuned independently to optimize its corresponding spectral slice. A second optical Fourier transformation recovers the time domain laser pulses. This method enables scalability of amplified bandwidth and pulse energy at the same time.
摘要翻译： 基于在时域脉冲之后的频域中进行放大的高功率参数放大的系统和方法进行光学傅里叶变换，以克服带宽限制。 简而言之，进行种子光谱的第一光学傅里叶变换，并且在该空间分散的频率平面中进行参数放大。 因此，可以使用包括彼此相邻放置的一系列光放大单元（例如不同窄带晶体）的光学放大介质来放大光谱的各个部分。 每个晶体被独立地调谐以优化其相应的光谱切片。 第二次光学傅立叶变换恢复时域激光脉冲。 该方法能够同时扩展带宽和脉冲能量。
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公开(公告)号：US08998562B2
公开(公告)日：2015-04-07
申请号：US13496357
申请日：2009-09-16
申请人： Horia Nica
发明人： Horia Nica
CPC分类号： F03D15/10 , F03D3/0409 , F03D3/061 , F03D9/25 , F03D9/32 , F05B2240/132 , Y02E10/721 , Y02E10/74 , Y10S415/907
摘要： A hollow rotor core assembly for a wind turbine with at least one set of cylindrical stacks having a plurality of guiding vanes on the internal surface of the cylindrical stacks, having at least one set of air openings to accept airflow into the hollow rotor core for creating when in rotation a vortex inside the hollow rotor core, having at one end a partial blocking device as such to allow the exhaust of only a fraction of the peripheral portion of the vortex and to redirect the remaining central portion of the vortex towards the other end of the hollow rotor core where the bulk of the airflow will be exhausted from the hollow rotor core.
摘要翻译： 一种用于风力涡轮机的空心转子芯组件，其具有至少一组圆柱形堆叠，其在所述圆柱形堆叠体的内表面上具有多个导向叶片，所述至少一组导向叶片具有至少一组空气开口，以接收空气流入所述中空转子芯中以产生 当在中空转子芯内部旋转涡流时，在一端具有局部阻塞装置，以允许仅排出涡流的周边部分的一部分，并将涡流的剩余中心部分朝向另一端 的中空转子芯，其中大部分气流将从空心转子芯排出。
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公开(公告)号：US08907205B2
公开(公告)日：2014-12-09
申请号：US13162186
申请日：2011-06-16
申请人： Riad Nechache , Andreas Ruediger , Federico Rosei
发明人： Riad Nechache , Andreas Ruediger , Federico Rosei
IPC分类号： H01L31/078 , H01L31/032 , H01L31/052
CPC分类号： H01L31/0521 , H01L31/032 , H01L31/056 , H01L31/078 , Y02E10/52
摘要： A solar cell comprising a semiconductor solar cell of a first band gap; a buffer layer formed on a surface of the semiconductor solar cell; and at least one layer of a multiferroic or a ferroelectric material formed on the buffer layer; wherein the at least one layer of a multiferroic or a ferroelectric material has a second bang gap, the first band gap being smaller than the second band gap.
摘要翻译： 一种太阳能电池，包括具有第一带隙的半导体太阳能电池; 形成在所述半导体太阳能电池的表面上的缓冲层; 以及形成在缓冲层上的至少一层多铁性或铁电材料层; 其中所述多铁性或铁电材料的所述至少一层具有第二凸起间隙，所述第一带隙小于所述第二带隙。
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公开(公告)号：US08900572B2
公开(公告)日：2014-12-02
申请号：US13523337
申请日：2012-06-14
CPC分类号： C12N5/0658 , A61K35/545 , C12N2501/60 , C12N2506/02 , C12N2506/45 , C12N2510/00 , C12N2799/022
摘要： Disclosed are methods of differentiating stem cells into muscle cells by growing the cells in a myogenic culture medium. The differentiated cells can be used as a source of cells for transplantation in a patient in need thereof.
摘要翻译： 公开了通过在肌生成培养基中生长细胞来将干细胞分化成肌肉细胞的方法。 分化的细胞可以用作有需要的患者中用于移植的细胞来源。
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