公开(公告)号：US11344872B2

公开(公告)日：2022-05-31

申请号：US16959880

申请日：2019-01-02

Applicant: INSTITUTE FOR BASIC SCIENCE ,  KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sukbok Chang ,  Seung Youn Hong ,  Yoon Su Park ,  Yeongyu Hwang ,  Yeong Bum Kim

IPC: C07F15/06 ,  C07F17/02 ,  B01J31/22 ,  C07D207/267 ,  C07D209/46 ,  C07D209/52 ,  C07D209/54 ,  C07D209/56 ,  C07D209/70 ,  C07D403/04 ,  C07D405/04 ,  C07D409/04 ,  C07J43/00

Abstract: The present invention relates to a novel metal complex, a method for producing same, and a method for producing a gamma-lactam compound using same, and the metal complex according to the present invention is used as a catalyst for producing a gamma-lactam compound and can efficiently produce a gamma-lactam compound with an excellent yield and excellent selectivity.

公开(公告)号：US20220164631A1

公开(公告)日：2022-05-26

申请号：US17530626

申请日：2021-11-19

Applicant: Korea Advanced Institute of Science and Technology

Inventor： Sang Wan Lee ,  Minryung Song

IPC: G06N3/04 ,  G06N3/063

Abstract: Various example embodiments relate to a computer system for profiling neural firing data and extracting content and a method thereof, and it may be configured to profile the neural firing data based on time series data representing firing timepoint for at least one neural firing within a window defined by a predetermined time length, and extract the content for the neural firing from the neural firing data.

公开(公告)号：US20220154283A1

公开(公告)日：2022-05-19

申请号：US17442012

申请日：2020-04-03

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION ,  KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hyun Koo KIM ,  Sung Hoi HONG ,  Yong PARK ,  Yeon Ho CHOI ,  Byeong Hyeon CHOI ,  Ji Ho PARK

IPC: C12Q1/6886

Abstract: According to an embodiment of the present disclosure, there is provided a marker composition for diagnosing cancer or predicting prognosis, comprising exosomes overexpressing a Tubulin alpha-1C chain (TUBA1C) protein.

公开(公告)号：US20220149217A1

公开(公告)日：2022-05-12

申请号：US17454404

申请日：2021-11-10

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sanghyeon KIM ,  DaeMyeong GEUM ,  SeungYeop AHN ,  Jinha LIM

IPC: H01L31/0352 ,  H01L31/0232 ,  H01L27/144 ,  H01L49/02 ,  H01L31/18

Abstract: Various embodiments relate to a superlattice photodetector and a method of manufacturing the same. The superlattice photodetector includes an absorption layer for absorbing incident light and a waveguide layer coupled with the absorption layer and enabling the incident light to be waveguided within the absorption layer. The waveguide layer may include a periodic structure in which a plurality of metal patterns and a plurality of dielectric patterns are repeatedly arranged. According to various embodiments, the superlattice photodetector can be thinned while having improved performance.

公开(公告)号：US20220146427A1

公开(公告)日：2022-05-12

申请号：US17583658

申请日：2022-01-25

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hongki YOO ,  Wooseop KIM ,  Juehyung KANG ,  Ungyo KANG

IPC: G01N21/64 ,  G02B21/04 ,  G02B21/16 ,  G02B21/00

Abstract: The multi-photon microscope comprises a repetition rate tuner that lowers an optical pulse train emitted from a pulsed laser to a repetition rate for time-gated detection, a scanner that scans the optical pulse train transmitted from the repetition rate tuner in x-axis and y-axis directions, an objective lens that irradiates an optical signal scanned by the scanner to the sample and acquires a fluorescence signal emitted from the excited fluorescent material, a photodetector that photoelectrically converts the fluorescence signal acquired by the objective lens, an amplifier that converts a current signal output from the photodetector into a voltage signal, a digitizer that samples the voltage signal output from the amplifier, and a computing device that separates sampling data output from the digitizer with a detection window set in time domain, and generates an image based on the sampling data separated by the detection window.

公开(公告)号：US11329725B2

公开(公告)日：2022-05-10

申请号：US17010277

申请日：2020-09-02

Applicant: Korea Advanced Institute of Science and Technology

Inventor： HyoHoon Park ,  Joonsup Shim ,  Seonghwan Kim ,  Hyun-Woo Rhee

IPC: H04B10/40 ,  H04Q11/00 ,  H04B10/11

Abstract: A device system for constituting a 3D image sensor based on optical phased array is provided. The device system includes an optical modulator that is integrated on the same photonic integrated circuit (PIC) chip as a laser diode array with different output wavelengths and a multiplexer for transmitting an optical wave having a wavelength selected from the laser diode array to an optical waveguide and modulates the optical wave into a specific optical signal, an optical phased array that radiates the optical signal received via an optical switch to the free space using a tunable transmit and receive (TRx) antenna array, and a photodetector that converts an Rx optical signal received by a Tx optical signal transmitted via the optical phased array into an electrical signal.

公开(公告)号：US20220136028A1

公开(公告)日：2022-05-05

申请号：US17515614

申请日：2021-11-01

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sang Yup LEE ,  Dongsoo Yang ,  Seon Young Park

IPC: C12P23/00 ,  C12N9/10 ,  C12N9/04 ,  C12N9/90 ,  C12N1/20 ,  C07K14/245 ,  C12P17/16

Abstract: Disclosed are a recombinant microorganism for producing a hydrophobic material, which is subjected to cell-membrane engineering in order to be imparted with at least one characteristic among an increase in a cell-membrane area, an increase in formation and secretion of an outer membrane vesicle, and an increase in formation of an inner membrane vesicle, and a cell-membrane engineering method for preparation thereof, whereby an insoluble hydrophobic material can be produced with high efficiency, the recombinant microorganism for high-efficiency production of carotenoids or violacein analogues is useful for producing natural pigments, antioxidants, antibiotics, cosmetic additives, anticancer agents, food additives, or nutritional supplements, and the natural pigment production technology developed herein achieves a great increase in production ability. Therefore, the present invention is effective at preparing a recombinant strain for efficient production of a variety of industrially and medically useful metabolites and at establishing an efficient preparation method.

公开(公告)号：US20220131546A1

公开(公告)日：2022-04-28

申请号：US17513657

申请日：2021-10-28

Applicant: Electronics And Telecommunications Research Institute ,  Korea Advanced Institute Of Science And Technology

Inventor： Han Gil CHOI ,  Sang Heung LEE ,  Seong Hwan CHO

IPC: H03L7/093 ,  H03L7/089 ,  H03L7/10

Abstract: The present invention relates to a frequency modulation method based on a phase-locked loop capable of performing fast modulation independent of bandwidth.
A frequency modulation system based on a phase-locked loop capable of performing fast modulation independent of bandwidth according to the present invention includes a loop filter including a proportional path and an integral path to determine a bandwidth of a phase-locked loop, a voltage-controlled oscillator configured to adjust a frequency according to an output of the loop filter, and a slope alternator configured to alternate an input current of the loop filter, wherein the slope alternator is located in the integral path of the loop filter to generate an offset current at a moment of change from a modulation rise to a modulation fall.

公开(公告)号：US20220126523A1

公开(公告)日：2022-04-28

申请号：US17508741

申请日：2021-10-22

Applicant: Korea Advanced Institute of Science and Technology

Inventor： JaeByum CHANG ,  Eunseok HEO ,  In CHO

IPC: B29C64/40 ,  B29C64/30 ,  B29C64/106 ,  B29C64/245

Abstract: Various embodiments provide a method of manufacturing a high-resolution structure using a size-tunable hydrogel. According to various embodiments, a basic structure may be fabricated. A temporary structure made of a hydrogel may be fabricated by applying a hydrogel to the basic structure. The temporary structure may shrink by dehydrating the hydrogel. This process may be repeated to fabricate smaller structures. The final structure may be fabricated using the temporary structure or the basic structure.

公开(公告)号：US11315222B2

公开(公告)日：2022-04-26

申请号：US16862958

申请日：2020-04-30

Applicant: SAMSUNG ELECTRONICS CO., LTD. ,  KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hyunseung Lee ,  MunChurl Kim ,  Yongwoo Kim ,  Jae Seok Choi ,  Youngsu Moon ,  Cheon Lee

IPC: G06T5/00 ,  G06T7/13 ,  G06T5/50

Abstract: An image processing apparatus obtains a first output image by applying an image to a first training network model, obtains a second output image by applying the image to a second training network model, and obtains a reconstructed image based on the first output image and the second output image. The first training network model is a model that uses a fixed parameter obtained through training of a plurality of sample images, the second training network model is trained to minimize a difference between a target image corresponding to the image and the reconstructed image.