公开(公告)号：US08529468B2

公开(公告)日：2013-09-10

申请号：US12496316

申请日：2009-07-01

申请人： Michael Hoffa ,  Michael E. Miller ,  Joseph L. Mark ,  Jacob Flagle ,  Justin Smith ,  Jason M. Butcher

发明人： Michael Hoffa ,  Michael E. Miller ,  Joseph L. Mark ,  Jacob Flagle ,  Justin Smith ,  Jason M. Butcher

IPC分类号： A61B10/02

CPC分类号： A61B10/0283 ,  A61B10/0275 ,  A61B2010/0093 ,  A61B2010/0208 ,  A61B2010/0225 ,  A61B2017/00477 ,  A61B2090/064

摘要： A surgical device is disclosed that comprises a cutting element, a biopsy line, a motor line, and a vacuum line. The cutting element includes an outer cannula and an inner cannula. The biopsy line is operatively connected to a control console for moving the inner cannula within the outer cannula to cut tissue cores. The motor line is operatively connected to the control console for operating the surgical device. The vacuum line is operatively connected to the inner cannula. A selectively openable tissue filter is operatively connected to the inner cannula, and is also connected to the vacuum line.

摘要翻译： 公开了一种包括切割元件，活检线，马达线和真空线的手术装置。 切割元件包括外套管和内套管。 活检线可操作地连接到控制台，用于移动外套管内的内套管以切割组织芯。 电动机线路可操作地连接到用于操作外科装置的控制台。 真空管线可操作地连接到内套管。 可选择打开的组织过滤器可操作地连接到内套管，并且还连接到真空管线。

公开(公告)号：US08430827B2

公开(公告)日：2013-04-30

申请号：US13243419

申请日：2011-09-23

申请人： Zachary R. Nicoson ,  Jacob Flagle ,  Michael E. Miller ,  Joseph L. Mark

发明人： Zachary R. Nicoson ,  Jacob Flagle ,  Michael E. Miller ,  Joseph L. Mark

IPC分类号： A61B10/0275

CPC分类号： A61B10/0275 ,  A61B10/0283 ,  A61B2010/0208

摘要： A biopsy device having a stylet, an outer cannula, and a vacuum chamber is disclosed. The stylet includes a lumen with an open proximal end and a tissue receiving opening near a distal end thereof. The outer cannula is slidably disposed over the stylet and has an open distal end with a cutting edge formed thereon. The vacuum chamber is in communication with the lumen of the stylet. Actuation of the outer cannula causes a vacuum to be delivered to the tissue receiving opening through the lumen of the stylet before the outer cannula advances distally.

摘要翻译： 公开了一种具有探针，外套管和真空室的活检装置。 探针包括具有开放近端的腔和在其远端附近的组织接收孔。 外套管可滑动地设置在通心针上方并且具有形成在其上的切割边缘的敞开的远端。 真空室与探针的内腔连通。 在外套管向远侧前进之前，外套管的致动导致真空通过探针的内腔被输送到组织接收口。

公开(公告)号：US08430825B2

公开(公告)日：2013-04-30

申请号：US12336054

申请日：2008-12-16

申请人： Joseph L. Mark

发明人： Joseph L. Mark

IPC分类号： A61B10/00

CPC分类号： A61B10/0275 ,  A61B10/0283 ,  A61B17/32002 ,  A61B17/320783 ,  A61B2010/0208 ,  A61B2017/00398 ,  A61B2017/320064 ,  A61B2090/0811

摘要： A tissue cutting device that is especially suited for neurosurgical applications is disclosed and described. The device includes a handpiece and an outer cannula in which a reciprocating inner cannula is disposed. The inner cannula includes a hinge between a body section and a cutting section that allows the cutting section to pivot when the inner cannula reciprocates within the outer cannula. A tissue collector is also provided and is in fluid communication with the lumen of the inner cannula. The inner cannula reciprocates at a rate that is greater than 1000 reciprocations per minute, and variable aspiration may also be provided to the device to control tissue traction and provide fine shaving and debulking.

摘要翻译： 公开并描述了特别适用于神经外科应用的组织切割装置。 该装置包括手柄和外套管，其中设置有往复式内插管。 内套管包括在主体部分和切割部分之间的铰链，其允许切割部分在内套管在外套管内往复运动时枢转。 还提供组织收集器并与内套管的内腔流体连通。 内套管以每分钟1000次往复运动的速率往复运动，并且还可以向装置提供可变抽吸以控制组织牵引并提供精细的剃刮和减压。

公开(公告)号：US08357103B2

公开(公告)日：2013-01-22

申请号：US11389274

申请日：2006-03-24

申请人： Joseph L. Mark ,  Michael E. Miller ,  Michael Hoffa ,  Zachary R. Nicoson ,  Terry D. Hardin ,  Inderjeet S. Jarial ,  William O. Hodge

发明人： Joseph L. Mark ,  Michael E. Miller ,  Michael Hoffa ,  Zachary R. Nicoson ,  Terry D. Hardin ,  Inderjeet S. Jarial ,  William O. Hodge

IPC分类号： A61B10/00 ,  A61B17/32

CPC分类号： A61B10/0266 ,  A61B10/0275 ,  A61B10/0283 ,  A61B2010/0208

摘要： A biopsy device having a cutting element is disclosed. The cutting element includes an inner cannula having a tissue receiving aperture disposed proximate a distal end thereof and an inner lumen. The inner cannula is slidably disposed within the inner lumen of an outer cannula. A vacuum chamber is disposed about at least a portion of the cutting element and is configured to create a vacuum in the cutting element during a biopsy procedure. The inner cannula is advanced distally outwardly and to cause the vacuum to be generated in the vacuum chamber. The vacuum is delivered to the cutting element whereby tissue is drawn into the tissue receiving aperture. The outer cannula is advanced distally outwardly after the inner cannula such that tissue drawn into the tissue cutting aperture is severed.

摘要翻译： 公开了一种具有切割元件的活检装置。 切割元件包括具有靠近其远端设置的组织接收孔和内腔的内套管。 内套管可滑动地设置在外套管的内腔内。 围绕切割元件的至少一部分设置真空室，并且构造成在活检过程期间在切割元件中产生真空。 内套管向外向外推进并且在真空室中产生真空。 真空被输送到切割元件，由此组织被拉入组织接收孔。 外套管在内套管之后向外远端前进，使得被拉入组织切割孔的组织被切断。

公开(公告)号：US20120289816A1

公开(公告)日：2012-11-15

申请号：US13474433

申请日：2012-05-17

申请人： Joseph L. Mark ,  Amin Kassam

发明人： Joseph L. Mark ,  Amin Kassam

IPC分类号： A61B1/32 ,  A61B5/055 ,  A61B10/02 ,  A61B6/02 ,  A61B8/13 ,  A61B6/00 ,  A61B5/00 ,  A61B6/03

CPC分类号： A61B17/3417 ,  A61B1/00135 ,  A61B1/00165 ,  A61B1/0607 ,  A61B1/313 ,  A61B1/32 ,  A61B5/0066 ,  A61B5/0071 ,  A61B5/0084 ,  A61B5/055 ,  A61B5/061 ,  A61B5/062 ,  A61B5/4064 ,  A61B6/12 ,  A61B6/501 ,  A61B6/5235 ,  A61B8/0808 ,  A61B8/0841 ,  A61B8/12 ,  A61B17/0293 ,  A61B17/32002 ,  A61B17/3421 ,  A61B90/50 ,  A61B90/98 ,  A61B2017/00477 ,  A61B2017/00907 ,  A61B2017/320008 ,  A61B2017/3405 ,  A61B2017/3454 ,  A61B2017/347 ,  A61B2034/2051 ,  A61B2034/2055 ,  A61B2034/2072 ,  A61B2090/0811 ,  A61B2090/103 ,  A61B2090/309 ,  A61B2090/3782 ,  A61B2090/3937 ,  A61B2090/3954 ,  A61B2090/3983 ,  A61M39/0247 ,  A61M2039/0205 ,  A61M2039/025 ,  A61M2039/0264 ,  A61M2039/0276 ,  A61M2039/0282 ,  A61M2210/0693

摘要： A surgical access assembly and method of use is disclosed. The surgical access assembly comprises an outer sheath and an obturator. The outer sheath and obturator are configured to be delivered to an area of interest within the brain. Either the outer sheath or the obturator may be configured to operate with a navigational system to track the location of either within the brain. Once positioned at a desired location, the obturator is removed, leaving a distal end of the outer sheath adjacent an area of interest, and creating a working corridor. Interrogation of the area of interest may be performed to evaluate a disorder and/or abnormality, as well as evaluate treatment regimes. Interventional devices may also be introduced to the area of interest, as well as a variety of treatments.

摘要翻译： 公开了一种手术进入组件和使用方法。 外科进入组件包括外护套和闭塞器。 外护套和闭孔器构造成被输送到大脑内的感兴趣区域。 外鞘或闭孔器可以被配置为与导航系统一起操作以跟踪脑内的位置。 一旦定位在期望的位置，就去除闭孔器，使外护套的远端邻近感兴趣的区域，并创建工作走廊。 可以进行感兴趣区域的询问以评估病症和/或异常，以及评估治疗方案。 还可以将介入装置引入感兴趣的区域，以及各种治疗方法。

公开(公告)号：US08206315B2

公开(公告)日：2012-06-26

申请号：US12241644

申请日：2008-09-30

申请人： Joseph L. Mark ,  Michael E. Miller

发明人： Joseph L. Mark ,  Michael E. Miller

IPC分类号： A61B10/00

CPC分类号： A61B10/0275 ,  A61B5/0059 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/0091 ,  A61B10/0283 ,  A61B2017/00022 ,  A61B2017/00057 ,  A61B2017/00061

摘要： A system for detecting abnormal tissue in a patient including an introducer cannula having a proximal opening and a distal opening. The system further includes a surgical instrument configured for selective insertion through the cannula. The surgical instrument further includes a tissue cutting opening positioned relative to the distal end of the introducer cannula when fully inserted through the introducer cannula. The system also includes a sensor configured to detect at least one property of the tissue of the patient. The sensor is located at a fixed distance relative to the distal end of the introducer cannula when the surgical instrument is inserted into the introducer cannula.

摘要翻译： 一种用于检测患者中异常组织的系统，包括具有近端开口和远端开口的导引套管。 该系统还包括构造成用于通过套管选择性插入的手术器械。 手术器械还包括当完全插入通过导引套管时相对于导引套管的远端定位的组织切割开口。 该系统还包括被配置为检测患者组织的至少一个特性的传感器。 当外科器械插入导引套管中时，传感器相对于导引套管的远端位于固定的距离处。

公开(公告)号：US08187204B2

公开(公告)日：2012-05-29

申请号：US12031423

申请日：2008-02-14

申请人： Michael E. Miller ,  Jake Flagle ,  Joseph L. Mark ,  Zachary R. Nicoson

发明人： Michael E. Miller ,  Jake Flagle ,  Joseph L. Mark ,  Zachary R. Nicoson

IPC分类号： A61B10/00

CPC分类号： A61B10/0275 ,  A61B90/50 ,  A61B2010/0208 ,  Y10T403/22

摘要： A method of using a surgical system that includes an outer cannula is disclosed. The method includes removably mounting a surgical device to an adapter. The adapter is secured to a stage. The surgical device and adapter is positioned at a predetermined location for inserting the outer cannula toward a target site in a body. Once positioned in the body, the outer cannula is fired to the target site. At least one tissue sample is taken using the surgical device and tissue samples are harvested from the surgical device.

摘要翻译： 公开了一种使用包括外套管的手术系统的方法。 该方法包括将外科装置可拆卸地安装到适配器上。 适配器固定在舞台上。 手术装置和适配器位于预定位置，用于将外套管插入体内的目标部位。 一旦定位在体内，外套管就会被射向目标部位。 使用手术装置取出至少一个组织样本，并从手术装置收集组织样本。

公开(公告)号：US20100152756A1

公开(公告)日：2010-06-17

申请号：US12336054

申请日：2008-12-16

申请人： Joseph L. Mark

发明人： Joseph L. Mark

IPC分类号： A61B17/32 ,  A61B10/00

CPC分类号： A61B10/0275 ,  A61B10/0283 ,  A61B17/32002 ,  A61B17/320783 ,  A61B2010/0208 ,  A61B2017/00398 ,  A61B2017/320064 ,  A61B2090/0811

摘要： A tissue cutting device that is especially suited for neurosurgical applications is disclosed and described. The device includes a handpiece and an outer cannula in which a reciprocating inner cannula is disposed. The inner cannula includes a hinge between a body section and a cutting section that allows the cutting section to pivot when the inner cannula reciprocates within the outer cannula. A tissue collector is also provided and is in fluid communication with the lumen of the inner cannula. The inner cannula reciprocates at a rate that is greater than 1000 reciprocations per minute, and variable aspiration may also be provided to the device to control tissue traction and provide fine shaving and debulking.

摘要翻译： 公开并描述了特别适用于神经外科应用的组织切割装置。 该装置包括手柄和外套管，其中设置有往复式内插管。 内套管包括在主体部分和切割部分之间的铰链，其允许切割部分在内套管在外套管内往复运动时枢转。 还提供组织收集器并与内套管的内腔流体连通。 内套管以每分钟1000次往复运动的速率往复运动，并且还可以向装置提供可变抽吸以控制组织牵引并提供精细的剃刮和减压。

公开(公告)号：US20100152614A1

公开(公告)日：2010-06-17

申请号：US12336086

申请日：2008-12-16

申请人： Joseph L. Mark

发明人： Joseph L. Mark

IPC分类号： A61B10/02 ,  A61B17/32 ,  A61M1/00

CPC分类号： A61B17/3205 ,  A61B10/0275 ,  A61B10/0283 ,  A61B17/32002 ,  A61B17/320783 ,  A61B2017/00398 ,  A61B2017/320064 ,  A61B2090/0811 ,  A61M1/0027 ,  A61M1/0039 ,  A61M1/0056

摘要： A tissue cutting device that is especially suited for neurosurgical applications is disclosed and described. The device includes a handpiece and an outer cannula in which a reciprocating inner cannula is disposed. The inner cannula includes a hinge between a body section and a cutting section that allows the cutting section to pivot when the inner cannula reciprocates within the outer cannula. A tissue collector is also provided and is in fluid communication with the lumen of the inner cannula. The inner cannula and the outer cannula define an annular space between the inner cannula and the outer cannula, and a seal is provided at the proximal end of the annular space. The seal is preferably a thixotropic, semi-solid material such as a high vacuum, halogenated polymeric grease. The device may also include an inner cannula stop position control for selectively controlling the position of the inner cannula when it is at rest.

摘要翻译： 公开并描述了特别适用于神经外科应用的组织切割装置。 该装置包括手柄和外套管，其中设置有往复式内插管。 内套管包括在主体部分和切割部分之间的铰链，其允许切割部分在内套管在外套管内往复运动时枢转。 还提供组织收集器并与内套管的内腔流体连通。 内套管和外套管在内套管和外套管之间限定一环形空间，并且在环形空间的近端设有密封件。 密封件优选为触变性半固体材料，例如高真空卤化聚合物润滑脂。 该装置还可以包括内套管停止位置控制，用于当内套管静止时选择性地控制内套管的位置。

公开(公告)号：US20100114031A1

公开(公告)日：2010-05-06

申请号：US12612422

申请日：2009-11-04

申请人： Inderjeet S. Jarial ,  Jason M. Butcher ,  Jacob Flagle ,  Jason Germann ,  Zachary R. Nicoson ,  William O. Hodge ,  Samantha Perkins ,  Joseph L. Mark ,  Aaron P. Barr ,  Michael Hoffa

发明人： Inderjeet S. Jarial ,  Jason M. Butcher ,  Jacob Flagle ,  Jason Germann ,  Zachary R. Nicoson ,  William O. Hodge ,  Samantha Perkins ,  Joseph L. Mark ,  Aaron P. Barr ,  Michael Hoffa

IPC分类号： A61B17/34

CPC分类号： A61B10/0275 ,  A61B2010/0208

摘要： An introducer assembly is disclosed. The introducer assembly comprises an introducer cannula, an introducer hub and an introducer stylet body. The introducer cannula is defined by a distal end and a proximal end and has a lumen extending therebetween. The introducer hub is operatively connected to the introducer cannula, and wherein the introducer hub is configured for selective connection with multiple medical devices. The introducer stylet body is defined by a proximal end and a distal end and is removably disposed within the introducer cannula. The introducer stylet body may further comprise an imagable feature having a predetermined size disposed on a distal end thereof.

摘要翻译： 公开了一种导引器组件。 导引器组件包括导引套管，导引器毂和导引器探针本体。 导引器套管由远端和近端限定，并且具有在其间延伸的内腔。 导引器毂可操作地连接到导引套管，并且其中引入器毂被配置为用于与多个医疗装置的选择性连接。 引导器探针主体由近端和远端限定，并且可移除地设置在导引套管内。 引导器探针主体还可以包括设置在其远端上的具有预定尺寸的可成像特征。