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    STABILISATION OF CARBONATE CALCIUM NANOPARTICLES
    84.
    发明公开
    STABILISATION OF CARBONATE CALCIUM NANOPARTICLES 审中-公开

    公开(公告)号：US20240067828A1

    公开(公告)日：2024-02-29

    申请号：US18270477

    申请日：2021-11-29

    申请人： LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST)

    发明人： Lauriane CHUZEVILLE ,  Jean-Sébastien THOMANN

    IPC分类号： C09C1/02

    CPC分类号： C09C1/021 ,  C01P2002/72 ,  C01P2004/03 ,  C01P2004/04 ,  C01P2004/52 ,  C01P2006/40

    摘要： The disclosure relates to lipid-coated calcium carbonate nanoparticles, said nanoparticles comprising an outer layer and a core being calcium carbonate nanoparticle, wherein said core is vaterite, proto-vaterite, or amorphous calcium carbonate as determined by X-Ray diffraction, wherein said core is at least partially coated with one or more amphiphilic compounds each having one hydrophilic head and at least one hydrophobic tail, remarkable in that the hydrophilic heads are negatively charged and form the outer layer of the nanoparticles, in that the nanoparticles have a surface charge having a ζ-potential below 0 mV as determined by micro-electrophoretic light scattering technology and in that said one or more amphiphilic compounds are PEG-free. The disclosure also relates to methods for forming such nanoparticles, for modulating the electrical charge of such nanoparticles as well as to the uses of such nanoparticles.

    HYDROGEN POTENTIAL SENSOR
    86.
    发明公开
    HYDROGEN POTENTIAL SENSOR 审中-公开

    公开(公告)号：US20230324330A1

    公开(公告)日：2023-10-12

    申请号：US18036430

    申请日：2021-11-10

    申请人： LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST)

    发明人： Cesar PASCUAL GARCIA ,  Damien LENOBLE

    IPC分类号： G01N27/414

    CPC分类号： G01N27/414

    摘要： A pH sensor comprises: a chamber for receiving an electrolyte solution; a first and a second ion-sensitive field effect transistor (ISFETs), each of the first and second ISFETs having a source terminal, a drain terminal and a transistor channel extending between the source terminal and the drain terminal, a dielectric layer with a sensing surface arranged in the chamber so as to be contactable by the electrolyte solution, the dielectric layer separating the sensing surface from the transistor channel; a first measurement circuit configured to measure a first source-drain resistance across the transistor channel of the first ISFET; and a second measurement circuit configured to measure a second source-drain resistance across the transistor channel of the second ISFET. The first and second measurement circuits include a common reference electrode, the reference electrode arranged contactable by the electrolyte solution in the chamber. The dielectric layer of first ISFET has a first thickness and the dielectric layer of the second ISFET has a second thickness different from the first thickness.

    PASSIVE SAMPLER DEPLOYMENT HOUSING
    88.
    发明申请
    PASSIVE SAMPLER DEPLOYMENT HOUSING 有权

    公开(公告)号：US20230022069A1

    公开(公告)日：2023-01-26

    申请号：US17788047

    申请日：2020-12-17

    申请人： LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST)

    发明人： Denis PITTOIS ,  Tom GALLÉ

    IPC分类号： G01N1/20

    摘要： A passive sampler deployment housing, the housing comprising a channel for guiding a stream flow of a liquid in a main direction, the channel having two side walls and one downstream wall, defining a sampling chamber; at least one support means adapted for supporting at least one detecting means and arranged in the channel, the downstream wall, disposed essentially perpendicular to the liquid main direction, having a height such that the flow of the liquid is accumulated in the channel at a level that is sufficient to overlap the support means and optionally the detecting means. The invention also relates to a device including the housing of and at least one detecting means, the at least one detecting means comprising a frame including two membrane supporting means, and a membrane, comprising a sorbing material, which is clamped therebetween.

    FOCAL PLANE DETECTOR
    89.
    发明申请
    FOCAL PLANE DETECTOR 有权

    公开(公告)号：US20220293407A1

    公开(公告)日：2022-09-15

    申请号：US17635475

    申请日：2020-08-14

    申请人： LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST)

    发明人： Hung Quang Hoang ,  Tom Wirtz

    IPC分类号： H01J49/02 ,  H01J49/00

    摘要： A detection device for detecting charges particles. The active area of the detector extends along a principal direction over several centimeters and up to 1 meter or more. This allows for its use as a focal plane detector for a mass spectrometer device, allowing to record all mass-to-charge ratios provided by the spectrometer in parallel and within a reduced acquisition time.

    AFFINITY SENSOR, IN PARTICULAR QCM SENSOR
    90.
    发明申请
    AFFINITY SENSOR, IN PARTICULAR QCM SENSOR 有权

    公开(公告)号：US20220291172A1

    公开(公告)日：2022-09-15

    申请号：US17636084

    申请日：2020-08-18

    申请人： LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST)

    发明人： Sivashankar KRISHNAMOORTHY ,  Matteo BEGGIATO

    IPC分类号： G01N29/02

    摘要： An aspect of the invention pertains to an affinity biosensor for sensing an analyte (a biomolecule) in a fluid, comprising an interface for contacting the fluid and adsorption of the analyte. The interface comprises a binary pattern of nanoscale regions having affinity for the analyte and a passivated region. The nanoscale regions are isolated from one another by the passivated region in such a way that adsorption of the analyte on the interface is confined to the nanoscale regions. The nanoscale regions have diameters comprised in the range from 5 to 200 nm. The nanoscale regions have together a surface area amounting to at least 15% of the surface area of the interface. A further aspect of the invention relates to a method of using such a sensor.