知搜-全球专利检索

  1. Login
  2. Sign Up

Search Results

129 records (took 0.018 seconds)

    Process for improved recovery of fermentation products from intracellular and extracellular presence
    72.
    发明申请
    Process for improved recovery of fermentation products from intracellular and extracellular presence 审中-公开
    从细胞内和细胞外存在改善发酵产物的回收方法

    公开(公告)号：US20110201054A1

    公开(公告)日：2011-08-18

    申请号：US12661547

    申请日：2010-03-18

    Applicant: Dilip S. Mehta ,  Anselm de Souza

    Inventor： Dilip S. Mehta ,  Anselm de Souza

    IPC: C12P7/26 ,  C12N9/00 ,  C12P19/42 ,  C12P7/62 ,  C12P17/06

    CPC classification number: C12P7/66 ,  B01D1/18 ,  C12P17/06 ,  C12P19/42 ,  C12P21/02

    Abstract: The present invention increases yield of the target fermented molecules by spray drying the fermentation broth and reducing the process volume to nearly one tenth the original. Thus, none of the target molecules are lost and requirements of the solvent and the other conventional method process equipments and processing materials are reduced considerably. Product recovery is improved. A major saving in the waste water treatment offsets spray drying and offers better process economics.

    Abstract translation: 本发明通过喷雾干燥发酵液并将处理量减少到原来的十分之一来提高目标发酵分子的产量。 因此，没有一个目标分子丢失，溶剂和其他常规方法的处理设备和加工材料的要求大大降低。 产品回收率提高。 主要节省废水处理抵消了喷雾干燥，并提供了更好的工艺经济性。

    Recombinant microorganism for the production of vitamin b6
    73.
    发明申请
    Recombinant microorganism for the production of vitamin b6 审中-公开
    用于生产维生素b6的重组微生物

    公开(公告)号：US20060228785A1

    公开(公告)日：2006-10-12

    申请号：US10528891

    申请日：2003-09-18

    Applicant: Tatsuo Hoshino ,  Keiko Ichikawa ,  Masaaki Tazoe

    Inventor： Tatsuo Hoshino ,  Keiko Ichikawa ,  Masaaki Tazoe

    IPC: C12P19/42 ,  C12N1/21

    CPC classification number: C12N9/0004 ,  C12P17/12

    Abstract: Disclosed is a recombinant microorganism being capable of producing vitamin B6, wherein said microorganism carries extra genes which code for an enzyme combination selected from: i) erythrose 4-phosphate dehydrogenase and 1-deoxy-D-xylulose 5-phosphate synthase; ii) erythrose 4-phosphate dehydrogenase and pyridoxol 5′-phosphate synthase; and iii) erythrose 4-phosphate dehydrogenase, 1-deoxy-D-xylulose 5-phosphate synthase and pyridoxol 5′-phosphate synthase.

    Abstract translation: 公开了能够产生维生素B6的重组微生物，其中所述微生物携带编码选自以下的酶组合的额外基因：i）赤藓糖-4-磷酸脱氢酶和1-脱氧-D-木酮糖-5-磷酸合酶; ii）赤藓糖-4-磷酸脱氢酶和吡哆醇5'-磷酸合酶; 和iii）赤藓糖-4-磷酸脱氢酶，1-脱氧-D-木酮糖-5-磷酸合成酶和吡哆醇5'-磷酸合酶。

    Process for producing vitamin B12 from hydrogen-metabolizing methane bacterium
    74.
    发明授权
    Process for producing vitamin B12 from hydrogen-metabolizing methane bacterium 失效
    从氢代谢甲烷细菌生产维生素B12的方法

    公开(公告)号：US06972188B2

    公开(公告)日：2005-12-06

    申请号：US10182624

    申请日：2001-02-01

    Applicant: Takaaki Maekawa ,  Zhen Ya Zhang

    Inventor： Takaaki Maekawa ,  Zhen Ya Zhang

    IPC: C12M1/40 ,  C12P3/00 ,  C12P5/02 ,  C12P19/42

    CPC classification number: C12P19/42 ,  C12P3/00 ,  Y02E50/343

    Abstract: Mesophilic methane bacteria obtained from digested sludge are acclimatized in an H2/CO2 medium and the acclimatized methane bacteria are grown on a support inclusive of inorganic nutritional salts of trace metal elements by using an immobilized bed bioreactor. The grown bacteria are allowed to metabolize a mixed gas, prepared by adding hydrogen to at least one of coal gas and biogas, into methane and at the same time, cobalamin contained in the fermented liquor is recovered as an extracellular product in the form of cyanocobalamin by using potassium cyanide to thereby produce vitamin B12 efficiently in a high content and high yield.

    Abstract translation: 从消化的污泥获得的嗜温甲烷细菌适应于H 2 N 2 CO 2/2培养基中，驯化的甲烷细菌生长在载体上，包括微量金属元素的无机营养盐 通过使用固定床生物反应器。 允许生长的细菌代替通过向煤气和沼气中的至少一种加入氢气而制备的混合气体到甲烷中，同时将发酵液中包含的钴胺素作为氰钴胺形式的细胞外产物回收 通过使用氰化钾从而以高含量和高产率有效地产生维生素B 12。

    Method for producing vitamin B12 from hydrogen-metabolizing methane bacterium
    75.
    发明申请
    Method for producing vitamin B12 from hydrogen-metabolizing methane bacterium 失效
    从氢代谢甲烷细菌生产维生素B12的方法

    公开(公告)号：US20050227332A1

    公开(公告)日：2005-10-13

    申请号：US11155613

    申请日：2005-06-20

    Applicant: Takaaki Maekawa ,  Zhenya Zhang

    Inventor： Takaaki Maekawa ,  Zhenya Zhang

    IPC: C12M1/40 ,  C12P3/00 ,  C12P5/02 ,  C12P19/42

    CPC classification number: C12P19/42 ,  C12P3/00 ,  Y02E50/343

    Abstract: Mesophilic methane bacteria obtained from digested sludge are acclimatized in an H2/CO2 medium and the acclimatized methane bacteria are grown on a support inclusive of inorganic nutritional salts of trace metal elements by using an immobilized bed bioreactor. The grown bacteria are allowed to metabolize a mixed gas, prepared by adding hydrogen to at least one of coal gas and biogas, into methane and at the same time, cobalamin contained in the fermented liquor is recovered as an extracellular product in the form of cyanocobalamin by using potassium cyanide to thereby produce vitamin B12 efficiently in a high content and high yield.

    Abstract translation: 从消化的污泥获得的嗜温甲烷细菌适应于H 2 N 2 CO 2/2培养基中，驯化的甲烷细菌生长在载体上，包括微量金属元素的无机营养盐 通过使用固定床生物反应器。 允许生长的细菌代替通过向煤气和沼气中的至少一种加入氢气而制备的混合气体到甲烷中，同时将发酵液中包含的钴胺素作为氰钴胺形式的细胞外产物回收 通过使用氰化钾从而以高含量和高产率有效地产生维生素B 12。

    Culture of Rhizobium cobalaminogenum capable of producing vitamin B.sub.12 and mutants thereof
    77.
    发明授权
    Culture of Rhizobium cobalaminogenum capable of producing vitamin B.sub.12 and mutants thereof 失效
    能够生产维生素B12及其突变体的钴绿假单胞菌的培养物

    公开(公告)号：US5538888A

    公开(公告)日：1996-07-23

    申请号：US487676

    申请日：1995-06-07

    Applicant: Satoru Asahi ,  Takahiko Yano ,  Muneharu Doi

    Inventor： Satoru Asahi ,  Takahiko Yano ,  Muneharu Doi

    IPC: C12P19/42 ,  A01N63/00 ,  C12N1/00 ,  C12N1/20

    CPC classification number: C12R1/41 ,  C12P19/42 ,  Y10S435/878

    Abstract: There is provided an economical, efficient and industrially useful method of producing vitamin B.sub.12 which comprises cultivating a microorganism belonging to Rhizobium cobalaminogenum which is capable of producing vitamin B.sub.12 in a culture medium to produce vitamin B.sub.12 and recovering the produced vitamin B.sub.12. There are also provided a microorganism belonging to Rhizobium cobalaminogenum which is capable of producing vitamin B.sub.12 and a microorganism Rhizobium cobalaminogenum 27B74 (FERM BP-4429).

    Abstract translation: 提供了一种生产维生素B12的经济，有效和工业上有用的方法，其包括培养能够在培养基中产生维生素B12以产生维生素B12并回收所生产的维生素B12的属于钴绿假单胞菌属的微生物。 还提供了能够产生维生素B12和微生物根瘤菌根瘤菌27B74（FERM BP-4429）的属于钴绿假单胞菌属的微生物。

    Process for the preparation of fermentation broth for coenzyme B.sub.12 and other corrinoid production
    78.
    发明授权
    Process for the preparation of fermentation broth for coenzyme B.sub.12 and other corrinoid production 失效

    公开(公告)号：US4659661A

    公开(公告)日：1987-04-21

    申请号：US648792

    申请日：1984-09-07

    Applicant: Laszlo Szemler ,  Eva C. Pechany ,  Maria Langer ,  Gyula Hruby ,  Valeria Sike

    Inventor： Laszlo Szemler ,  Eva C. Pechany ,  Maria Langer ,  Gyula Hruby ,  Valeria Sike

    IPC: C12N1/32 ,  C12P19/42 ,  C12N1/20 ,  C12P39/00 ,  C12R1/01

    CPC classification number: C12P19/42 ,  Y10S435/822

    Abstract: The invention relates to a process for the preparation of a fermentation broth containing coenzyme B.sub.12, with a new, anaerobic, mesophilic, methane-producing mixed micropopulation, under anaerobic, septic conditions, using a new broth containing methanol, precursors and partially known nutrients,In the new process according to the invention the improvement consists in(a) removing 5 to 15 volume percent of the inoculum fermentation broth containing the anaerobic, mesophilic, methan-producing new mixed micropopulation and replacing same with an equal volume of a broth containing cornsteep liquor hydrolysate and/or corn slops of hydrolysate thereof and other known nutrients, the number and concentration of which has been reduced, for 6 to 8 days, and if desired, further manufacturing the fermentation broth removed,(b) after reaching an assimilation velocity of at least 0.15 to 0.2 g methanol/lit. fermentation broth/hour, continuing removal of the fermentation broth as described in step (a) but replacing same with a broth supplemented with ammonium sulfate and o-xylidine, and continuing fermentation for 6 to 8 days, and if desired, further manufacturing the fermentation broth removed,(c) after achieving an assimilation velocity of 0.2 to 0.3 g methanol/lit. fermentation broth/hour--i.e. after converting the inoculum fermentation broth into a maintaining fermentation broth--continuing removal of the fermentation broth and addition of fresh broth as described in step (b), and if desired, interrupting the removal of fermentation broth for several days, and(d) adding of the removed maintaining fermentation broth on the first day nutrients according to step (b), and if desired, on the second day only methanol, cornsteep liquor or cornsteep liquor hydrolysate and ammonium carbonate and further manufacturing the fermentation broth obtained, which is suitable for batchwise production, and(e) repeating steps (a), (c) and (d) daily.

    Process for obtaining metal-free corrinoids
    79.
    发明授权
    Process for obtaining metal-free corrinoids 失效
    获得无金属类胡萝卜素的方法

    公开(公告)号：US4407947A

    公开(公告)日：1983-10-04

    申请号：US302022

    申请日：1981-09-14

    Applicant: Volker Koppenhagen ,  Gerhard Schlingmann ,  Bernd Dresow ,  Ludwig Bischoff ,  Rosemarie Penkert ,  Eicke Siefert

    Inventor： Volker Koppenhagen ,  Gerhard Schlingmann ,  Bernd Dresow ,  Ludwig Bischoff ,  Rosemarie Penkert ,  Eicke Siefert

    IPC: C12P17/18 ,  C12P19/42 ,  C12R1/01 ,  C12P19/28

    CPC classification number: C12P19/42 ,  C12P17/182

    Abstract: A process for obtaining metal-free corrinoids consisting of inoculating a culture media free of added compounds of metals of the VIIIth group of the Periodic Table with a parent strain of Rhodopseudomonas, cultivating under illumination, repeating the steps of inoculating and cultivating employing said culture media and said illumination employing a part of the sequential culture from the preceding stage as an inoculum in each subsequent state, for a series of several pre-production culture stages, inoculating said culture media with the preceding sequential culture for the last time, cultivating under illumination, separating the microorganism from the culture media of the production culture stage and isolating metal-free corrinoids from the culture media of the production culture stage.

    Abstract translation: 一种获得无金属类胡萝卜素的方法，该方法包括将不含周期表第八组的金属的添加化合物的培养基与红假单胞菌的亲本菌株接种，在照射下培养，重复使用所述培养基接种和培养的步骤 并将所述照射采用来自前一阶段的连续培养物的一部分作为每种后续状态的接种物，用于一系列预生产培养阶段，最后接种具有先前顺序培养的所述培养基，在照明条件下培养 从生产培养阶段的培养基中分离微生物，并从生产培养阶段的培养基中分离出无金属的类固醇。

Patent Agency Ranking