公开(公告)号：US2758006A

公开(公告)日：1956-08-07

申请号：US53215944

申请日：1944-04-21

Applicant: CARTER JAMES M ,  KAMEN MARTIN D

Inventor： CARTER JAMES M ,  KAMEN MARTIN D

IPC: B01D59/44 ,  C22B60/02

CPC classification number: B01D59/44 ,  C22B60/0278

公开(公告)号：US2754423A

公开(公告)日：1956-07-10

申请号：US54691944

申请日：1944-07-27

Applicant: LAWRENCE ERNEST O

Inventor： LAWRENCE ERNEST O

IPC: B01D59/44

CPC classification number: B01D59/44

公开(公告)号：US2725478A

公开(公告)日：1955-11-29

申请号：US60595945

申请日：1945-07-19

Applicant: WRIGHT BYRON T

Inventor： WRIGHT BYRON T

IPC: B01D59/44

CPC classification number: B01D59/44

公开(公告)号：US2714664A

公开(公告)日：1955-08-02

申请号：US53640144

申请日：1944-05-19

Applicant: LAWRENCE ERNEST O

Inventor： LAWRENCE ERNEST O

IPC: B01D59/44

CPC classification number: B01D59/44

公开(公告)号：US2714165A

公开(公告)日：1955-07-26

申请号：US67988246

申请日：1946-06-28

Applicant: REID JOHN D

Inventor： REID JOHN D

IPC: B01D59/44

CPC classification number: B01D59/44

公开(公告)号：US20140312219A1

公开(公告)日：2014-10-23

申请号：US14323275

申请日：2014-07-03

Applicant: Spectro Analytical Instruments GmbH

Inventor： Dirk ARDELT ,  Ulrich HEYNEN ,  Adi A. Scheidemann

IPC: H01J49/32

CPC classification number: H01J49/025 ,  B01D59/44 ,  H01J49/322

Abstract: An inorganic mass spectrometer capable of measuring a relevant and large or the full mass spectral range simultaneously may include a suitable ion source (e.g., an ICP mass spectrometer with an ICP ion source), an ion transfer region, ion optics to separate ions out of a plasma beam, a Mattauch-Herzog type mass spectrometer with a set of charged particle beam optics to condition the ion beam before an entrance slit, and a solid state multi-channel detector substantially separated from ground potential and separated from the potential of the magnet.

Abstract translation: 能够同时测量相关的和大的或全质谱范围的无机质谱仪可以包括合适的离子源（例如，具有ICP离子源的ICP质谱仪），离子转移区域，离子光学器件，用于将离子从 等离子体束，具有一组带电粒子束光学器件的Mattauch-Herzog型质谱仪，用于在入射狭缝之前调节离子束，以及基本上与地电位分离并与磁体的电位分离的固态多通道检测器 。

公开(公告)号：US20140110661A1

公开(公告)日：2014-04-24

申请号：US14137840

申请日：2013-12-20

Applicant: Daojing Wang ,  Pan Mao ,  Hung-Ta Wang ,  Peidong Yang

Inventor： Daojing Wang ,  Pan Mao ,  Hung-Ta Wang ,  Peidong Yang

IPC: H01L49/00

CPC classification number: H01L49/00 ,  B01D59/44 ,  B01L3/5027 ,  G01N30/72 ,  G01N30/7206 ,  H01J49/0018 ,  H01J49/04 ,  H01J49/167

Abstract: The present invention provides for a structure comprising a plurality of emitters, wherein a first nozzle of a first emitter and a second nozzle of a second emitter emit in two directions that are not or essentially not in the same direction; wherein the walls of the nozzles and the emitters form a monolithic whole. The present invention also provides for a structure comprising an emitter with a sharpened end from which the emitter emits; wherein the emitters forms a monolithic whole. The present invention also provides for a fully integrated separation of proteins and small molecules on a silicon chip before the electrospray mass spectrometry analysis.

Abstract translation: 本发明提供了一种包括多个发射器的结构，其中第一发射器的第一喷嘴和第二发射体的第二喷嘴在不是或基本上不是相同方向的两个方向上发射; 其中喷嘴和发射器的壁形成整体。 本发明还提供了一种结构，其包括具有尖端的发射器，发射器从该发射器发射; 其中发射器形成整体。 本发明还提供了在电喷雾质谱分析之前在硅芯片上完全整合蛋白质和小分子的分离。

公开(公告)号：US20140070086A1

公开(公告)日：2014-03-13

申请号：US13943130

申请日：2013-07-16

Applicant: SHIMADZU CORPORATION ,  RIKEN

Inventor： Koji Ueda ,  Atsuhiko Toyama

IPC: H01J49/00

CPC classification number: H01J49/0027 ,  B01D59/44 ,  G01N33/6848 ,  G01N33/6854 ,  G01N2400/00 ,  G01N2440/38 ,  H01J49/00 ,  Y10T436/173076 ,  Y10T436/24

Abstract: In order to provide an analysis method that is capable of determining a glycan structure with high detection sensitivity, a method of the present invention includes the steps of: carrying out triple quadrupole mass spectrometry at various values of CID energy; creating an energy-resolved profile including yield curves representing relationships between (i) a value of the CID energy and (ii) measured amounts of specific types of product ions; preparing a reference profile, and identifying a glycan structure of a test material by comparing the energy-resolved profile with the reference profile.

Abstract translation: 为了提供能够确定具有高检测灵敏度的聚糖结构的分析方法，本发明的方法包括以下步骤：以各种CID能量进行三重四极杆质谱; 产生能量分辨曲线，其包括表示（i）CID能量的值和（ii）特定类型的产物离子的测量量之间的关系的收益率曲线; 准备参考分布图，以及通过将能量分辨分布与参考分布进行比较来识别测试材料的聚糖结构。

公开(公告)号：US08598519B2

公开(公告)日：2013-12-03

申请号：US13164590

申请日：2011-06-20

Applicant: Craig M. Whitehouse ,  Thomas Dresch ,  Bruce Andrien

Inventor： Craig M. Whitehouse ,  Thomas Dresch ,  Bruce Andrien

IPC: B01D59/44

CPC classification number: B01D59/44 ,  H01J49/0481 ,  H01J49/063

Abstract: A method includes directing ions from an atmospheric pressure ion source to a first ion guide; directing ions in the first ion guide to a second ion guide, the second ion guide being a multipole ion guide extending along an axis; periodically directing ions along the axis; receiving at least some of the ions in a time-of-flight analyzer; accelerating the ions in the time-of-flight mass analyzer orthogonal to the axis; and detecting the accelerated ions.

Abstract translation: 一种方法包括将离子从大气压离子源引导到第一离子导向器; 将所述第一离子导向器中的离子引导到第二离子引导件，所述第二离子引导件是沿着轴线延伸的多极离子引导件; 沿着轴定期引导离子; 在飞行时间分析仪中接收至少一些离子; 加速与轴垂直的飞行时间质量分析仪中的离子; 并检测加速离子。

公开(公告)号：US20130248365A1

公开(公告)日：2013-09-26

申请号：US13991295

申请日：2011-12-02

Applicant: Frédéric Chartier ,  Valérie Geersten ,  Laurent Vio ,  Gérard Crétier

Inventor： Frédéric Chartier ,  Valérie Geersten ,  Laurent Vio ,  Gérard Crétier

IPC: G01N27/447

CPC classification number: G01N27/44721 ,  B01D59/42 ,  B01D59/44 ,  G01N27/447 ,  G01N27/44717 ,  G01N27/44756 ,  G01N2030/8868 ,  H01J49/105

Abstract: A method for isotope measurement of charged species contained in a solution to be analyzed, particularly charged species having an isobaric interference, has the following consecutive steps: a) in the capillary of a capillary electrophoresis device, the solution to be analyzed is inserted contiguously between a terminating electrolyte and a leading electrolyte that, respectively, are placed after the inlet and before the outlet of the capillary and contain ions of the same charge but with mobility inferior and superior to those of said species; b) separating the species by using the capillary electrophoresis device according to the isotachophoresis mode; then c) in the continuity of the preceding step, performing an isotope measurement of the species detected in the form of a substantially constant amplitude signal by using an inductively coupled plasma mass spectrometer (ICPMS) connected by direct coupling with the capillary electrophoresis device.

Abstract translation: 在待分析溶液中所含的带电物质的同位素测量方法，特别是具有等压干扰的带电物质的方法具有以下连续步骤：a）在毛细管电泳装置的毛细管中，待分析溶液相邻插入 末端电解质和前导电解质，其分别放置在毛细管的入口之后并且在毛细管的出口之前并且含有相同电荷的离子，但其迁移率低于和优于所述物质的离子; b）根据等电泳方式使用毛细管电泳装置分离物种; 然后c）在前述步骤的连续性中，通过使用通过与毛细管电泳装置直接耦合连接的电感耦合等离子体质谱仪（ICPMS），以基本上恒定幅度信号的形式检测的物种进行同位素测量。