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公开(公告)号:US11369601B2
公开(公告)日:2022-06-28
申请号:US16769008
申请日:2018-11-30
申请人: TOHOKU UNIVERSITY
IPC分类号: A61K31/496 , A61K9/00 , A61K31/4184
摘要: An object to be achieved by the present invention is to provide a novel preventive or therapeutic agent for pulmonary hypertension containing as an active ingredient a compound that has not been known for a therapeutic effect on pulmonary hypertension heretofore. The present invention provides a preventive or therapeutic agent for pulmonary hypertension, including at least one kind selected from the group consisting of mebendazole and itraconazole or a salt thereof.
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公开(公告)号:US20220200566A1
公开(公告)日:2022-06-23
申请号:US17600756
申请日:2020-03-31
申请人: TOHOKU UNIVERSITY
发明人: Michio KADOTA , Shuji TANAKA
摘要: A high-order mode surface acoustic wave device includes a piezoelectric substrate (11) formed from a LiTaO3 or LiNbO3 crystal and an interdigital transducer electrode (12) embedded in a surface of the piezoelectric substrate (11) to use a surface acoustic wave in a high-order mode. Further, the high-order mode surface acoustic wave device may include a film (13) or substrate stacked on the piezoelectric substrate (11), and may include a support substrate (11) and/or a multi-layer film (15) provided in contact with a surface opposite to the surface of the piezoelectric substrate (11) on which the interdigital transducer electrode (12) is provided. The high-order mode surface acoustic wave device may achieve good characteristics and maintain a sufficient mechanical strength even in a high frequency band of 3.8 GHz or greater.
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公开(公告)号:US20220198891A1
公开(公告)日:2022-06-23
申请号:US17690983
申请日:2022-03-09
申请人: TOHOKU UNIVERSITY
发明人: Masashi KONYO , Kosuke YAMAGUCHI , Nan CAO , Satoshi TADOKORO
摘要: A vibration control apparatus configured to control a vibration generated by a vibration apparatus, using a signal, includes processer circuitry, and an energy controller configured to convert a waveform of the signal while maintaining energy of the signal.
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公开(公告)号:US20220198247A1
公开(公告)日:2022-06-23
申请号:US17043203
申请日:2019-03-29
申请人: TOHOKU UNIVERSITY
发明人: Yitao MA , Tetsuo Endoh
摘要: There is provided a neural network circuit device including a plurality of synapse circuits storing a synaptic coupling weight and a neuron circuit connected to the plurality of synapse circuits. The plurality of synapse circuits store the synaptic coupling weight in a non-volatile manner and output a voltage signal having a magnitude based on the stored synaptic coupling weight in response to an input signal. The neuron circuit includes a neuron MOS transistor having a floating gate and a plurality of control gates which are capacitively coupled to the floating gate and to which the voltage signals from the plurality of synapse circuits are input respectively, and a pulse generator outputting a pulse signal by turning on or off the neuron MOS transistor.
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公开(公告)号:US20220175724A1
公开(公告)日:2022-06-09
申请号:US17442173
申请日:2020-03-25
发明人: Takaaki Abe , Shinobu Ohnuma , Michiaki Unno , Kenichiro Hayashi
IPC分类号: A61K31/405 , A61P35/00 , A61K9/00
摘要: An object of the present invention is to provide a low molecular weight compound having a prophylactic or therapeutic action on cancer. A compound of the following formula (1), a compound of the following formula (2), or the like can be administered by a method such as oral administration to prevent or treat cancers such as colorectal cancer.
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公开(公告)号:US20220157361A1
公开(公告)日:2022-05-19
申请号:US17430000
申请日:2020-02-15
申请人: TOHOKU UNIVERSITY
发明人: Masanori Natsui , Daisuke Suzuki , Akira Tamakoshi , Takahiro Hanyu , Tetsuo Endoh , Hideo Ohno
摘要: The present invention provides a device with low power and high performance, which can be applied to sensor nodes, a sensor node using the same, an access controller, a data transfer method, and execute a processing method in a microcontroller. The device has: an MRAM; a non-volatile CPU configured to include a nonvolatile memory; a non-volatile FPGA-ACC configured to include a nonvolatile memory and execute a part of operations on the nonvolatile CPU; and a power-gating control unit that controls power supply to each memory cell in the MRAM, the non-volatile CPU, and the non-volatile FPGA-ACC. The device is further provided with an access controller that controls accesses to the MRAM by reading data in advance and backing up the data when data is to be read from the MRAM.
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公开(公告)号:US20220140174A1
公开(公告)日:2022-05-05
申请号:US17512673
申请日:2021-10-28
IPC分类号: H01L31/153 , H01L31/02 , H01L31/0203 , H01L31/0216
摘要: A display device includes a substrate including a first surface, and a second surface positioned at a side opposite to the first surface; a first light-emitting element located at a lateral side of the substrate; a plurality of light-receiving elements located at a second surface side of the substrate; a plurality of second light-emitting elements located on the first surface of the substrate; and a first drive element controlling driving of the second light-emitting elements based on output of the light-receiving elements. A light-emitting surface of the first light-emitting element is oriented in a first direction. The first direction is parallel to a direction from the first surface toward the second surface. Light-emitting surfaces of the second light-emitting elements are oriented in a second direction. The second direction is from the second surface toward the first surface.
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公开(公告)号:US20220101916A1
公开(公告)日:2022-03-31
申请号:US17037492
申请日:2020-09-29
发明人: YOSHIHISA SEKIGUCHI , TETSUO ENDOH
摘要: A memory device includes: a cell array that includes a first region including first memory cells and a second region including second memory cells; first word lines connected to each of the first memory cells; second word lines connected to each of the second memory cells; a first bit line commonly connected to the first memory cells and the second memory cells; a row decoder that selects one of the first word lines and one of the second word lines in parallel during a data read operation; and a sense amplifier between the first region and the second region and electrically connected to the first bit line during the data read operation.
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公开(公告)号:US11287431B2
公开(公告)日:2022-03-29
申请号:US16192042
申请日:2018-11-15
申请人: TOHOKU UNIVERSITY
发明人: Hiroaki Shimokawa , Kimio Satoh , Nobuhiro Kikuchi
摘要: A primary object of the present invention is to provide a method for conveniently and accurately testing for pulmonary hypertension. To achieve this object, the present invention provides a method for testing for pulmonary hypertension using as an indicator the concentration of selenoprotein P protein in a sample derived from a subject.
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公开(公告)号:US20220087550A1
公开(公告)日:2022-03-24
申请号:US17541463
申请日:2021-12-03
申请人: TOHOKU UNIVERSITY
发明人: Makoto YOSHIZAWA , Norihiro SUGITA , Taihei NORO , Taiki IKEMIYA
IPC分类号: A61B5/021
摘要: An apparatus for estimating a blood pressure includes a first pulse wave information detector configured to detect first pulse wave information at a first position of a living body, a second pulse wave information detector configured to detect second pulse wave information at a second position of the living body, the second position being spaced a distance in a vertical direction from the first position; and a blood pressure estimator configured to estimate, based on pulse wave amplitude information at the first position and the second position obtained from the first pulse wave information obtained by the first pulse wave information detector and the second pulse wave information obtained by the second pulse wave detector and the distance in the vertical direction, a blood pressure of the living body.
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