公开(公告)号：US07524842B2

公开(公告)日：2009-04-28

申请号：US11653511

申请日：2007-01-16

Applicant: Brian J. Lavey ,  Joseph A. Kozlowski ,  Guowei Zhou ,  Ling Tong ,  Wensheng Yu ,  Michael K. C. Wong ,  Bandarpalle B. Shankar ,  Neng-Yang Shih ,  M. Arshad Siddiqui ,  Kristin E. Rosner ,  Chaoyang Dai ,  Janeta Popovici-Muller ,  Vinay M. Girijavallabhan ,  Dansu Li ,  Razia Rizvi ,  Lei Chen ,  De-Yi Yang ,  Robert Feltz ,  Seong Heon Kim

Inventor： Brian J. Lavey ,  Joseph A. Kozlowski ,  Guowei Zhou ,  Ling Tong ,  Wensheng Yu ,  Michael K. C. Wong ,  Bandarpalle B. Shankar ,  Neng-Yang Shih ,  M. Arshad Siddiqui ,  Kristin E. Rosner ,  Chaoyang Dai ,  Janeta Popovici-Muller ,  Vinay M. Girijavallabhan ,  Dansu Li ,  Razia Rizvi ,  Lei Chen ,  De-Yi Yang ,  Robert Feltz ,  Seong Heon Kim

IPC: A61K31/428 ,  A61K31/4015 ,  A61K31/4166 ,  C07D209/04 ,  C07D233/24 ,  C07D277/34 ,  C07D417/06

CPC classification number: C07D403/14 ,  C07D401/06 ,  C07D401/14 ,  C07D403/06 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D473/00

Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-α or combinations thereof.

Abstract translation: 本发明涉及式（I）化合物或其药学上可接受的盐，溶剂合物或异构体，其可用于治疗由MMP，ADAM，TACE，聚集蛋白聚糖蛋白酶，TNF-α或其组合介导的疾病或病症 。

公开(公告)号：US07474978B2

公开(公告)日：2009-01-06

申请号：US11591760

申请日：2006-10-31

Applicant: Kok Keong Richard Lum ,  Lei Chen

Inventor： Kok Keong Richard Lum ,  Lei Chen

IPC: G01C17/38

CPC classification number: H03F3/087 ,  H03F1/08 ,  H03F1/34 ,  H03F3/082 ,  H03F2200/153 ,  H03F2203/45518 ,  H03F2203/45528 ,  H03G3/3084

Abstract: An optical receiver having a photodetector, amplifier, feedback loop, and output circuit is disclosed. The photodetector generates a current between first and second nodes in response to being illuminated with light. The amplifier has an input connected to the first node and an output connected to a third node. The feedback path connects the third node to the first node, and includes a diode in series with a circuit element having an impedance greater than a predetermined value, the diode is connected between the first and fourth nodes. The output circuit is connected to the fourth node and provides an output signal to an external circuit. The output circuit can be configured to provide an output signal that is proportional to the logarithm of the intensity of the light that illuminates the photodetector.

Abstract translation: 公开了一种具有光电检测器，放大器，反馈回路和输出电路的光接收器。 光电检测器响应于用光照亮而在第一和第二节点之间产生电流。 放大器具有连接到第一节点的输入端和连接到第三节点的输出。 反馈路径将第三节点连接到第一节点，并且包括与阻抗大于预定值的电路元件串联的二极管，二极管连接在第一和第四节点之间。 输出电路连接到第四节点，并向外部电路提供输出信号。 输出电路可以被配置为提供与照亮光电检测器的光的强度的对数成比例的输出信号。

公开(公告)号：US20080101803A1

公开(公告)日：2008-05-01

申请号：US11591760

申请日：2006-10-31

Applicant: Kok Keong Richard Lum ,  Lei Chen

Inventor： Kok Keong Richard Lum ,  Lei Chen

IPC: H04B10/06

CPC classification number: H03F3/087 ,  H03F1/08 ,  H03F1/34 ,  H03F3/082 ,  H03F2200/153 ,  H03F2203/45518 ,  H03F2203/45528 ,  H03G3/3084

Abstract: An optical receiver having a photodetector, amplifier, feedback loop, and output circuit is disclosed. The photodetector generates a current between first and second nodes in response to being illuminated with light. The amplifier has an input connected to the first node and an output connected to a third node. The feedback path connects the third node to the first node, and includes a diode in series with a circuit element having an impedance greater than a predetermined value, the diode is connected between the first and fourth nodes. The output circuit is connected to the fourth node and provides an output signal to an external circuit. The output circuit can be configured to provide an output signal that is proportional to the logarithm of the intensity of the light that illuminates the photodetector.

Abstract translation: 公开了一种具有光电检测器，放大器，反馈回路和输出电路的光接收器。 光电检测器响应于用光照亮而在第一和第二节点之间产生电流。 放大器具有连接到第一节点的输入端和连接到第三节点的输出。 反馈路径将第三节点连接到第一节点，并且包括与阻抗大于预定值的电路元件串联的二极管，二极管连接在第一和第四节点之间。 输出电路连接到第四节点，并向外部电路提供输出信号。 输出电路可以被配置为提供与照亮光电检测器的光的强度的对数成比例的输出信号。

公开(公告)号：US20080028271A1

公开(公告)日：2008-01-31

申请号：US11550567

申请日：2006-10-18

Applicant: Lei Chen

Inventor： Lei Chen

IPC: H03M13/00

CPC classification number: H03M13/116 ,  H03M13/033 ,  H03M13/1151 ,  H03M13/1515

Abstract: In a LDPC based communications system, a method for generating LDPC codes is provided. The method comprises the steps of: constructing a base matrix; providing a plurality of sub-matrices for forming the base matrix, with each sub-matrix being a cyclic permutation matrix; and masking the base matrix using a small sparse matrix.

Abstract translation: 在基于LDPC的通信系统中，提供了一种用于生成LDPC码的方法。 该方法包括以下步骤：构建基本矩阵; 提供用于形成基本矩阵的多个子矩阵，其中每个子矩阵是循环置换矩阵; 并使用小的稀疏矩阵来掩蔽基本矩阵。

公开(公告)号：US20070103232A1

公开(公告)日：2007-05-10

申请号：US11267422

申请日：2005-11-04

Applicant: Lei Chen ,  Richard Lum

Inventor： Lei Chen ,  Richard Lum

IPC: H03F1/36

CPC classification number: H03F3/45183 ,  H03F1/08 ,  H03F1/34 ,  H03F3/45475 ,  H03F2200/153 ,  H03F2200/36 ,  H03F2203/45288 ,  H03F2203/45512 ,  H03F2203/45652

Abstract: An operational amplifier is described. The operational amplifier includes a first stage, a second stage, a third stage, and a fourth stage. The amplifier includes a nested transconductance-capacitance compensation configuration. The third stage includes class AB control mechanism. The fourth stage includes a class AB output stage.

公开(公告)号：US07208086B2

公开(公告)日：2007-04-24

申请号：US10773020

申请日：2004-02-04

Applicant: Siu Choon Ng ,  Chi Bun Ching ,  Lifeng Zhang ,  Lei Chen

Inventor： Siu Choon Ng ,  Chi Bun Ching ,  Lifeng Zhang ,  Lei Chen

IPC: B01D15/08

CPC classification number: G01N30/482 ,  B01D15/3833 ,  B01J20/3204 ,  B01J20/3208 ,  B01J20/3217 ,  B01J20/3219 ,  B01J20/3274 ,  B01J20/3282 ,  B01J2220/52 ,  B01J2220/54 ,  C07B57/00 ,  C08B37/0012

Abstract: A novel conjugate of a support material and an oligomer or polymer of a saccharide that is linked to the support material via urea linkages, and in which the oligomers or polymers are cross-linked via urea linkages provides a valuable stationary phase for chromatography. It is particularly valuable as a chiral stationary phase in enantiomeric separations and enantiomeric analysis.

Abstract translation: 载体材料和通过尿素键与载体材料连接的寡聚物或聚合物的新型缀合物，其中低聚物或聚合物通过脲键交联提供了有价值的色谱固定相。 作为对映体分离和对映异构体分析中的手性固定相是特别有价值的。

公开(公告)号：US20060132606A1

公开(公告)日：2006-06-22

申请号：US11316459

申请日：2005-12-22

Applicant: Tzu-Hsuan Lan ,  Lei Chen

Inventor： Tzu-Hsuan Lan ,  Lei Chen

IPC: H04N17/00

CPC classification number: H04N17/002

Abstract: A calibration method and an image capture apparatus including a calibrator are provided. The image capture apparatus includes a window glass, an image sensor under the window glass, and a calibrator. The calibrator is disposed above the image sensor and includes a first portion and a second portion. During the calibration of the image apparatus, the image sensor scans the first portion to generate a first calibration data and scans the second portion to generate a second calibration data. Then the image sensor employs the first calibration data and the second calibration data to derive the third calibration data, which is used for the image sensor to calibrate the scan results.

Abstract translation: 提供了包括校准器的校准方法和图像捕获装置。 图像捕获装置包括窗玻璃，窗玻璃下的图像传感器和校准器。 校准器设置在图像传感器上方并且包括第一部分和第二部分。 在图像设备的校准期间，图像传感器扫描第一部分以产生第一校准数据，并扫描第二部分以产生第二校准数据。 然后，图像传感器使用第一校准数据和第二校准数据来导出用于图像传感器校准扫描结果的第三校准数据。

公开(公告)号：US20060001969A1

公开(公告)日：2006-01-05

申请号：US10989448

申请日：2004-11-15

Applicant: Jian Wang ,  Xuegong Deng ,  Lei Chen

Inventor： Jian Wang ,  Xuegong Deng ,  Lei Chen

IPC: G02B5/18 ,  H01L21/338

CPC classification number: G02B5/1833 ,  G02B5/1809 ,  G02B5/1866 ,  G11B7/1365

Abstract: Gratings and related devices and systems are disclosed.

Abstract translation: 公开了光栅和相关设备和系统。

公开(公告)号：US06720285B2

公开(公告)日：2004-04-13

申请号：US09888088

申请日：2001-06-22

Applicant: Siu Choon Ng ,  Chi Bun Ching ,  Lifeng Zhang ,  Lei Chen

Inventor： Siu Choon Ng ,  Chi Bun Ching ,  Lifeng Zhang ,  Lei Chen

IPC: B01J2000

CPC classification number: G01N30/482 ,  B01D15/3833 ,  B01J20/3204 ,  B01J20/3208 ,  B01J20/3217 ,  B01J20/3219 ,  B01J20/3274 ,  B01J20/3282 ,  B01J2220/52 ,  B01J2220/54 ,  C07B57/00 ,  C08B37/0012

Abstract: A conjugate of a support material and an oligomer or polymer of a saccharide that is linked to the support material via urea linkages, and in which the oligomers or polymers are cross-linked via urea linkages provides a valuable stationary phase for chromatography. It is particularly valuable as a chiral stationary phase in enantiomeric separations and enantiomeric analysis.

Abstract translation: 载体材料和通过尿素键与载体材料连接的糖的低聚物或聚合物的缀合物，其中低聚物或聚合物通过脲键交联提供了有价值的色谱固定相。 作为对映体分离和对映异构体分析中的手性固定相是特别有价值的。

公开(公告)号：US06587999B1

公开(公告)日：2003-07-01

申请号：US09859149

申请日：2001-05-15

Applicant: Lei Chen ,  Sandeep Bhutani ,  Nianging Zhang

Inventor： Lei Chen ,  Sandeep Bhutani ,  Nianging Zhang

IPC: G06F945

CPC classification number: G06F17/5022

Abstract: A method of modeling delays in an integrated circuit design is disclosed that may be used to reduce the computation time of path delays in an integrated circuit design. A method of modeling delays in an integrated circuit design includes the steps of receiving as input a description of an integrated circuit design; identifying at least one small net in the integrated circuit design from the description; approximating an effective capacitance of the at least one small net by the total capacitance; and approximating an interconnect delay of the at least one small net by zero.

Abstract translation: 公开了一种用于集成电路设计中的延迟建模的方法，其可用于减少集成电路设计中的路径延迟的计算时间。 一种对集成电路设计中的延迟进行建模的方法包括以下步骤：接收作为输入的集成电路设计的描述; 从描述中识别集成电路设计中的至少一个小网; 将所述至少一个小网的有效电容近似于总电容; 以及将所述至少一个小网络的互连延迟近似为零。