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公开(公告)号：US20220399198A1
公开(公告)日：2022-12-15
申请号：US17753922
申请日：2020-09-29
Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.
Inventor： Takashi Baba
Abstract: Pole electrodes (150) are disclosed for use in an ion reaction apparatus, e.g., an electron induced dissociation cell, to reduce fouling due to polymer build-up and increase the useful lifetime of such electrodes. To reduce fouling, the novel pole electrode designs include a X-shaped aperture (160) in lieu of the conventional central circular aperture. The pole electrodes are particularly useful in systems having a plurality of branched electrodes (152) defining a first axis for controlled passage of charged ions and a transverse axis for passage of an electron beam. The pole electrodes are adapted for disposition between an electron source and the branched electrodes to provide an aperture for passage of an electron beam while also impeding escape of ions and reaction products from the apparatus. The X-shaped aperture eliminates or reduces the portion of the pole electrode surface that is most prone to fouling by polymeric build-up.
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公开(公告)号：US11515137B2
公开(公告)日：2022-11-29
申请号：US17242040
申请日：2021-04-27
Applicant: Agilent Technologies, Inc.
Inventor： Tong Chen , Gershon Perelman , Curt A. Flory
IPC: H01J49/06
Abstract: An ion guide includes electrodes elongated along an axis from an entrance end to an exit end and spaced around the axis to surround an interior. The electrodes have polygonal shapes with inside surfaces disposed at a radius from the axis and having an electrode width tangential to a circle inscribed by the electrodes. An aspect ratio of the electrode width to the radius varies along the axis. The electrodes are configured to generate a two-dimensional RF electrical field in the interior having a multipole composition comprising one or more lower-order multipole components and one or more higher-order multipole components and varying along the axis in accordance with the varying aspect ratio, and having an RF voltage amplitude that varies along the axis.
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公开(公告)号：US20220367167A1
公开(公告)日：2022-11-17
申请号：US17663074
申请日：2022-05-12
Applicant: Analytik Jena GmbH
Inventor： Roland Lehmann , Wolfram Weisheit , Iouri Kalinitchenko
Abstract: A method of operating an inductively coupled plasma mass spectrometry apparatus for analyzing an analyte sample, the mass spectrometry apparatus including a plasma ion source, a mass analyzer and an interface arrangement positioned between the plasma ion source and the mass analyzer of the mass spectrometer, the interface arrangement at least including an interface structure, including a sampling or skimmer cone, and at least one passage with an inlet and an outlet into a reaction zone, the method including: generating a plasma using the plasma ion source and forming a plasma flux to flow towards the mass analyzer; supplying the analyte sample into the reaction zone via the passage such that the analyte sample interacts with the plasma flux; and analyzing the analyte sample using the mass analyzer.
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64.发明授权公开(公告)号：US11460440B2
公开(公告)日：2022-10-04
申请号：US17063636
申请日：2020-10-05
Applicant: Ching Wu
Inventor： Ching Wu
Abstract: The present invention relates to a preconcentrator for vapors and particles collected from air. The vapor preconcentrator is made from plural layer of coils. The coil is made of resistance alloy. The pitch size of the coil is made to precisely trap/filter out certain size of the particles during preconcentration. Multiple coils could be made with different pitch sizes to achieve multiple step filtrations. When the sample flow enters the preconcentrator chamber, it passes through the coils. The particles of different sizes are trapped on different layer of coils. The vapor sample can be trapped on any coils when interacted with the coil surface. They could be trapped without any affinitive coating as the preconcentrator is at relatively low temperature. Different coils or different sections of the coil can be coated with different material to trap chemicals of different classes. During the desorption process, the coils are flash heated with controlled temperature ramping speed to evaporate the trapped chemicals. Various configurations, constructions, and methods of operation are presented.
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公开(公告)号：US20220301845A1
公开(公告)日：2022-09-22
申请号：US17713550
申请日：2022-04-05
Applicant: Bruker Scientific LLC
Inventor： Melvin Andrew PARK
IPC: H01J49/42 , H01J49/06 , H01J49/40 , G01N27/623
Abstract: An ion mobility separator comprises an RF-device for transversely confining ions in an ion region using: (a) a first set of electrodes arranged parallel to one another along a direction of ion travel to define a first transverse boundary of the ion region, and that are supplied with a first RF-voltage such that different phases of the first RF-voltage are applied to adjacent electrodes of the first set; and (b) a second set of electrodes arranged parallel to one another along said direction of ion travel to define a second transverse boundary of the ion region, and that are supplied with a second RF-voltage such that different phases of the second RF-voltage are applied to adjacent electrodes of the second set, the first and second transverse boundaries being substantially opposite each other in a transverse direction of the ion region and the first and second RF voltages having different frequencies.
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Patent Agency Ranking
公开(公告)号：US20220293409A1
公开(公告)日：2022-09-15
申请号：US17830984
申请日：2022-06-02
Applicant: Thermo Fisher Scientific (Bremen) GmbH
Inventor： Alexander A. Makarov , Wilko Balschun , Jan-Peter Hauschild , Denis Chernyshev , Eduard V. Denisov
Abstract: The present invention provides an electrode arrangement 10, 10′ for an ion trap, ion filter, an ion guide, a reaction cell or an ion analyser. The electrode arrangement 10, 10′ comprises an RF electrode 12a, 12b, 12a′, 12b′ mechanically coupled to a dielectric material 11. The RF electrode 12a, 12b, 12a′, 12b′ is mechanically coupled to the dielectric material 11 by a plurality of separators 13 that are spaced apart and configured to define a gap between the RF electrode 12a, 12b, 12a′, 12b′ and the dielectric material 11. Each of the plurality of separators 13 comprises a projecting portion 13b and the dielectric material 11 comprises corresponding receiving portions 11a such that on coupling of the RF electrode 12a, 12b, 12a′, 12b′ to the dielectric material 11, the projecting portion 13b of each separator 13 is received within the corresponding receiving portion 11a of the dielectric material 11. The present invention also relates to an ion trap comprises the electrode arrangement 10, 10′ and a method of manufacturing the electrode arrangement 10, 10′.
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公开(公告)号：US20220277949A1
公开(公告)日：2022-09-01
申请号：US17737622
申请日：2022-05-05
Applicant: Bruker Scientific LLC
Inventor： Melvin Andrew PARK
Abstract: The invention provides hybrid mass spectrometric systems which comprise an ion source, a first trapped ion mobility spectrometry (TIMS) analyzer and a mass analyzer, wherein the TIMS analyzer is located and operated in a first vacuum chamber at an elevated pressure above 500 Pa, and methods for operating the hybrid mass spectrometric systems.
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公开(公告)号：US11415547B2
公开(公告)日：2022-08-16
申请号：US17274877
申请日：2019-09-10
Applicant: Micromass UK Limited
Inventor： David J. Langridge , Jason Lee Wildgoose , Martin Raymond Green , Daniel James Kenny , Kevin Giles , Steven Derek Pringle
IPC: G01N27/623 , H01J49/00 , H01J49/06 , G01N27/447 , G01N27/49 , G01N15/00
Abstract: A method of filtering ions according to their ion mobility using a device is disclosed, the method comprising a plurality of electrodes and one or more voltage source(s) arranged and adapted to apply voltages to the plurality of electrodes, the method comprising, generating using the one or more voltage source(s) one or more local separation region(s), wherein ions can be separated within each local separation region according to their ion mobility, and moving each local separation region axially along the device with a certain velocity such that, for each local separation region, ions having a value of their ion mobility falling within a selected range are transmitted axially along the device with that local separation region whereas ions having higher and/or lower ion mobility falling outside that range escape the local separation region, wherein any ions that escape the local separation region(s) are removed from within the device and/or otherwise kept apart from those ions falling within the selected range(s).
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公开(公告)号：US20220254619A1
公开(公告)日：2022-08-11
申请号：US17622568
申请日：2020-07-22
Applicant: DH Technologies Development PTE. LTD.
Inventor： Bruce COLLINGS , Pascal MARTIN
Abstract: In one aspect, a method of modulating transmission of ions in a mass spectrometer is disclosed, which comprises generating an ion beam comprising a plurality of ions, directing the ion beam to an ion optic positioned in the path of the ion beam, wherein the ion optic includes at least one opening through which the ions can pass, and applying one or more voltage pulses at a selected duty cycle to said ion optic so as to obtain a desired attenuation of brightness of the ion beam passing through the ion optic, where a pulse width of said voltage pulses at said selected duty cycle is determined by identifying a pulse width on a calibration normalized ion intensity versus pulse width relation for said ions that corresponds to said desired attenuation on an ideal normalized ion intensity versus pulse width relation for said ions.
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公开(公告)号：US11410844B2
公开(公告)日：2022-08-09
申请号：US16950607
申请日：2020-11-17
Applicant: HONEYWELL INTERNATIONAL INC.
Inventor： Benjamin Spaun , Zachary Price , Matthew Swallows
Abstract: Devices, methods, and systems for enclosures for an ion trapping device are described herein. One enclosure for an ion trapping device includes a heat spreader base that includes a plurality of apertures. The ion trapping device may also include a grid array having a plurality of pins extending outward from a surface of the grid array. The apertures of the heat spreader base may be arranged such that the plurality of pins passes through the plurality of apertures.
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