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公开(公告)号:US11456163B1
公开(公告)日:2022-09-27
申请号:US16877811
申请日:2020-05-19
摘要: The present invention relates to methods of improving analytical instruments and improved analytical instruments. The aforementioned method employs a calibration correction module that calibrates the machine to effect measurements with the minimum possible relative squared error. This results in a significant improvement of the analytical instrument in question that leads to more precise and accurate results.
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公开(公告)号:US11408869B2
公开(公告)日:2022-08-09
申请号:US16341216
申请日:2017-10-12
申请人: SHELL OIL COMPANY
IPC分类号: G01N33/00 , B01J4/00 , B01J8/04 , G01N30/06 , G01N30/24 , G01N30/68 , G01N30/70 , G01N30/88 , C07C31/20 , C07D317/38 , G01N30/02
摘要: The present invention relates to method and an apparatus for quantitatively analyzing a gaseous process stream, in particular a stream from a process for producing ethylene carbonate and/or ethylene glycol, in particular where such stream comprises gaseous organic iodides.
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公开(公告)号:US20220244273A1
公开(公告)日:2022-08-04
申请号:US17619290
申请日:2020-06-12
发明人: Kyoung Heon KIM , Hoon Suk CHA , Joong Kyong AHN , Jung Yeon KIM , Yu Eun CHEONG
摘要: The present invention relates to a method for diagnosing the severity of rheumatoid arthritis using metabolite analysis. The present invention provides a biomarker which is for classifying the severity of rheumatoid arthritis in patients suffering from same through the analysis of joint capsule fluid metabolites, and can be applied to a kit for more specifically classifying the severity of rheumatoid arthritis in patients.
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公开(公告)号:US20220214318A1
公开(公告)日:2022-07-07
申请号:US17595492
申请日:2020-05-08
发明人: Jan Schwellenbach , Volkmar Thom , Dominik Stein
摘要: A chromatography method, a method of determining the concentration of at least one compound in a chromatography method and a method of obtaining at least one chromatography method parameter are provided. The methods can include selecting at least one compound, a stationary phase, a mobile phase, and/or a chromatography device having a chromatography bed comprising the stationary phase and the mobile phase.
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公开(公告)号:US11372013B2
公开(公告)日:2022-06-28
申请号:US16408279
申请日:2019-05-09
申请人: Shimadzu Corporation
发明人: Koki Miyazaki , Shinji Tanaka
摘要: To suppress generation of dew condensation in temperature control space when heating temperature control is performed. In an apparatus, an air temperature control part for cooling or heating air in temperature control space has a first temperature control element for performing at least cooling of air, and a second temperature control element for performing at least heating of air downstream of the first temperature control element. In this manner, when heating temperature control is performed, cooling and dehumidification of air taken in from an air intake portion can be performed by the first temperature control element, and then heating of the dehumidified air can be performed by the second temperature control element.
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公开(公告)号:US20220185868A1
公开(公告)日:2022-06-16
申请号:US17672777
申请日:2022-02-16
申请人: CMC BIOLOGICS A/S
发明人: Mads LAUSTSEN , Simon BERGMANN
IPC分类号: C07K16/00 , G01N30/46 , G01N30/88 , C07K1/36 , B01D15/18 , B01D15/20 , B01D15/38 , B01D15/42 , C12M1/26
摘要: Provided is a bioreactor arrangement for producing a biopolymer expressed by a cell and a continuous process for a capturing the biopolymer employing two chromatography units operated in series or independently.
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公开(公告)号:US11360058B2
公开(公告)日:2022-06-14
申请号:US16341622
申请日:2017-10-25
申请人: Ohio University
发明人: Hao Chen
摘要: A method of quantifying a target compound includes applying an oxidation/reduction potential to an electrochemical cell (14); measuring an electrochemical current during the application of the oxidation/reduction potential; and ionizing and directing the target compound before and after the application of the oxidation/reduction potential to a mass spectrometer (16) that measures a target compound ion intensity. The method further includes determining a target compound ion intensity change due to the application of the oxidation/reduction potential and determining a total amount of the target compound in the sample using the measured electrochemical current and the target compound ion intensity change. Determining the target compound ion intensity change may comprise either comparing the target compound ion intensity before and after the electrolysis relative to a reference peak or comparing the integrated peak area of a target compound ion in an extracted ion chromatogram before and after the electrolysis.
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公开(公告)号:US20220170895A1
公开(公告)日:2022-06-02
申请号:US17599286
申请日:2020-03-30
申请人: Micromass UK Limited
发明人: Donald Mason , Heather Brown
IPC分类号: G01N30/88 , B05B17/06 , H01J49/04 , C12Q1/6883 , A61B5/01
摘要: A method of newborn screening (“NBS”) is disclosed comprising directing ultrasonic energy or ultrasonic waves into a metabolite or analyte sample derived from a newborn, neonate or infant so as to cause a mist of charged sample droplets or sample ions to be ejected. The charged sample droplets or sample ions are then mass analysed and a determination is made as to whether or not one or more first metabolites or analytes indicative of a disorder or inborn error are present in the sample.
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公开(公告)号:US20220128530A1
公开(公告)日:2022-04-28
申请号:US17570250
申请日:2022-01-06
发明人: Jichun HAN
摘要: A method for analyzing aromatic compounds, and a reagent kit for LC-MS analysis of aromatic compounds. The method includes preparing a diazonium reagent, contacting aromatic compounds in a sample with the diazonium reagent to form an analyte; and measuring an amount or ratio of the analyte. The reagent kit includes a diazonium reagent, wherein the diazonium reagent includes (i) a diazonium salt that contains a diazonium ion; (ii) an amine and nitrous acid; and/or (iii) a nitrite and an acid.
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公开(公告)号:US20220128523A1
公开(公告)日:2022-04-28
申请号:US17430915
申请日:2020-02-24
申请人: Cytiva Sweden AB
摘要: The present invention relates to a computer-implemented method for controlling preparation of a liquid mixture comprising an acid and its conjugate base or a base and its conjugate acid. The method comprises obtaining (S11) a composition for the liquid mixture to be prepared and determining (S12) a plurality of settings for controlling a preparation of the liquid mixture in one or more automated processes. The plurality of settings are provided (S13) to one or more control systems of the one or more automated processes. The present invention also relates to a buffer tool configured to perform the computer-implemented method, a buffer management system comprising the buffer tool, and a computer readable storage medium (25), having stored thereon a computer program which, when executed in a buffer tool, causes execution of the computer-implemented method.
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