SYSTEMS AND METHODS FOR SCREENING ASYMPTOMATIC VIRUS EMITTERS

    公开(公告)号:US20210338101A1

    公开(公告)日:2021-11-04

    申请号:US17236994

    申请日:2021-04-21

    Abstract: A method comprising at least one light source configured to generate a light of at least one wavelength and project the light over an optical path, a sample device, the device containing a sample obtained from exhalation of a person, a vortex mask configured to receive the light after the light passes through at least a portion of the sample device, the vortex mask including a series of concentric circles etched in a substrate, the vortex mask configured to provide destructive interference of coherent light received from the at least one light source, a detector configured to detect and measure wavelength intensities from the light in the optical path, the wavelength intensities being impacted by the light passing through the sample, the detector receiving the light that remained after passing through the vortex mask, and a processor configured to provide measurement results based on the wavelength intensities.

    Photonic Circuit With Integrated Light Coupler

    公开(公告)号:US20210294034A1

    公开(公告)日:2021-09-23

    申请号:US16326504

    申请日:2017-08-18

    Inventor: Tom Claes

    Abstract: An integrated photonic device may include an image detector that comprises an array of pixels. The device may further include an integrated waveguide and a light coupler comprising a light receiving part optically coupled to the integrated waveguide for receiving a light signal. The light coupler may be adapted for coupling a same predetermined spectral band of the light signal to each of a plurality of pixels of the image detector. The light coupler may include a tapered portion, in which the light coupler tapers outward in a direction of propagation, and an end part comprising an elliptically shaped back reflector for reflecting light propagating along the direction of propagation back through the light coupler toward the integrated waveguide.

    Systems and user interface for collecting a data set in a flow cytometer

    公开(公告)号:US11125674B2

    公开(公告)日:2021-09-21

    申请号:US16591453

    申请日:2019-10-02

    Inventor: Collin A. Rich

    Abstract: Systems in a flow cytometer having an interrogation zone and illumination impinging the interrogation zone include: a lens subsystem including a collimating element that collimates light from the interrogation zone, a light dispersion element that disperses collimated light into a light spectrum, and a focusing lens that focuses the light spectrum onto an array of adjacent detection points; a detector array, including semiconductor detector devices, that collectively detects a full spectral range of input light signals, in which each detector device detects a subset spectral range of the full spectral range of light signals; and a user interface that enables a user to create a set of virtual detector channels by grouping detectors in the detector array, such that each virtual detector channel corresponds to a detector group and has a virtual detector channel range including the sum of subset spectral ranges of the detectors in the corresponding detector group.

    CONCAVE DIFFRACTION GRATING, METHOD FOR PRODUCING THE SAME, AND OPTICAL DEVICE

    公开(公告)号:US20210271008A1

    公开(公告)日:2021-09-02

    申请号:US17258818

    申请日:2019-04-24

    Abstract: The present invention provides a concave diffraction grating capable of improved diffraction efficiency by suppressing spherical aberration. The concave diffraction grating is a concave diffraction grating 2 for dispersing and focusing light and comprises sawtooth grating grooves 21 on a concave substrate 24, with the sawtooth grating grooves 21 being unequally spaced. The concave diffraction grating 2 for dispersing and focusing light is formed by preparing a planar diffraction grating with a sawtooth shape which is formed on a planar substrate by photo-lithography and etching or machining and which forms unequally spaced grating grooves 21, deforming and mounting the planar diffraction grating along a fixed convex substrate to obtain a mold of a concave diffraction grating, and transferring the mold of the concave diffraction grating to the surface of a metal or a resin.

    MULTI-DISPERSIVE SPECTROMETER
    68.
    发明申请

    公开(公告)号:US20210231499A1

    公开(公告)日:2021-07-29

    申请号:US17054157

    申请日:2020-03-25

    Abstract: A multi-dispersive spectrometer is provided in which the spectrometer comprises an an optical system configured to direct an excitation signal from an excitation light source toward a sample, receive a spectroscopy signal from the sample, and direct the spectroscopy signal toward the detector. The optical system comprises a movable optical component adapted to move the spectroscopy signal relative to at least one sensor of the detector and the detector is adapted to detect a plurality of discrete shifted spectroscopy signals. A method of obtaining a Raman spectrum from a sample is also provided. The method comprises directing an excitation signal from an excitation light source toward a sample; receiving a spectroscopy signal from the sample; and directing the spectroscopy signal toward a detector, wherein the spectroscopy signal is moved relative to at least one sensor of the detector to provide a plurality of discrete shifted spectroscopy signals.

    Multi-stage parallel spectroscopy systems and methods

    公开(公告)号:US11060912B2

    公开(公告)日:2021-07-13

    申请号:US16705694

    申请日:2019-12-06

    Abstract: A multi-stage parallel spectroscopy system has a plurality of dispersion stages, with the output of one dispersion stage serving as input to the next dispersion stage. Each dispersion stage separates input radiation into respective spectral components along a respective dispersion axis. In embodiments, the dispersion axes for the dispersion stages are substantially parallel to each other. Thus, the disclosed systems may be considered single-axis parallel spectroscopy configurations, in contrast to cross-axis parallel spectroscopy configurations. An optical system disposed in an optical path between dispersion stages can spatially filter a set of wavelengths from the input to the next dispersion stage to increase spectral extinction without sacrificing throughput or parallel operation. In some embodiments, the same dispersive element provides the spectral separation for multiple dispersion stages, by way of a recirculating optical system that redirects the spectral output from the dispersive element back to its input.

    Spectrophotometer
    70.
    发明授权

    公开(公告)号:US11054308B2

    公开(公告)日:2021-07-06

    申请号:US16616151

    申请日:2018-04-24

    Abstract: Observation light can be applied to a position for measurement without providing large space in a spectrophotometer, and the position for measurement can be easily known. A slit is disposed at a position optically conjugate with the position for measurement in the spectrophotometer. Light from an object to be measured passes through the slit, travels along a measurement optical path, and is subject to wavelength dispersion by a wavelength dispersing element. An observation light source is retracted outside the measurement optical path at the time of measuring a spectral spectrum. At the time of observing the position for measurement, the observation light source is inserted into the measurement optical path, and emits observation light toward the slit. Alternatively, light from an object to be measured passes through the slit, and is diffracted by a grating. The observation light source is disposed on an optical path of zeroth light. The observation light source emits observation light toward the grating at the time of observing the position for measurement.

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