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公开(公告)号：US11365288B2
公开(公告)日：2022-06-21
申请号：US17038293
申请日：2020-09-30
Applicant: Alcon Inc.
Inventor： Steve Yun Zhang , Daqing Wu , Junhao Ge , Richard Charles Breitkopf , Xinming Qian , Zach Munoz , Matthew D. Nelson , Augustine Twum Kumi , Weihong Lang , Ying Zheng , Feng Jing , Frank Chang
IPC: C08G77/442 , C08G77/20 , C08G77/388 , C08G77/392 , C08G77/14 , C08L83/10 , G02B1/04 , C08G77/12 , B29D11/00 , G02C7/04
Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.
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公开(公告)号：US20220134692A1
公开(公告)日：2022-05-05
申请号：US17518432
申请日：2021-11-03
Applicant: Alcon Inc.
Inventor： Yuan Chang , Junhao Ge , Steve Yun Zhang
Abstract: Described herein is a method for producing photochromic contact lenses, in particular, photochromic silicone hydrogel contact lenses. The method comprises a step of cast molding of a lens-forming composition including a vinylic monomer having a primary amino or thiolactone group to form an unprocessed contact lens having the polymer matrix of which have pendant primary amino or thiolactone groups, a step of one-pot multistep reactions based on thiolactone chemistry (aminolysis and thiol-induced graft polymerization of a photochromic vinylic monomer to the polymer matrix) which are carried out only in its central region which is circular and concentric with the central axis of the unprocessed contact lens. The obtained photochromic contact lens has a central pupillary region that only can undergo a reversible color change upon exposure to UV/HEVL-radiation.
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公开(公告)号：US20210347929A1
公开(公告)日：2021-11-11
申请号：US17313459
申请日：2021-05-06
Applicant: Alcon Inc.
Inventor： Jing Cheng , Yang Zheng , Steve Yun Zhang , Lindsay Olson
IPC: C08F283/12 , C08J3/075
Abstract: The invention provides a contact lens manufacturing method comprising a process for removing unprocessed molded silicone hydrogel contact lenses from mold halves in a relatively efficient and consistent manner. The method of the invention involves using a silicone fluid (or so-called silicone oil) as non-reactive diluent in SiHy lens formulation for making SiHy contact lenses. Resultant SiHy contact lenses cast-molded from such a SiHy lens formulation can have a significantly reduced adhesion force with the molding surfaces of a lens mold and consequently a higher efficiency and consistency in removing unprocessed molded SiHy contact lenses from mold halves can be achieved. This method of the invention can be easily implemented in a production environment for enhancing the production yield.
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公开(公告)号：US20210292557A1
公开(公告)日：2021-09-23
申请号：US17205186
申请日：2021-03-18
Applicant: Alcon Inc.
Inventor： Jing Cheng , Steve Yun Zhang
Abstract: The invention is generally related to an insert for being embedded in a silicone hydrogel contact lens. The insert is made of a crosslinked materials which are rigid in dry state at room temperature (from about 22° C. to about 26° C.), have a high oxygen permeability and a high refractive index in fully hydrated state. Such materials are useful for making inserts in embedded contact lenses for correcting corneal astigmatism, presbyopia, and color blindness lenses and for imparting photochromic characteristics to the lenses. The invention is also related to a method for making embedded silicone hydrogel contact lenses comprising an insert of the invention therein and to embedded silicone hydrogel contact lenses comprising an insert of the invention therein.
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公开(公告)号：US20250052927A1
公开(公告)日：2025-02-13
申请号：US18795402
申请日：2024-08-06
Applicant: Alcon Inc.
Inventor： Ya-Wen Chang , Steve Yun Zhang
Abstract: Described herein is a UV/HEVL-filtering SiHy contact lens that not only has a relatively high UV/HEVL filtering capability but also has an aesthetic appealing color. The bulk silicone hydrogel of the UV/HEVL-filtering SiHy contact lens comprises repeating units of (1) at least one hydrophilic vinylic monomer, (2) at least one siloxane-containing vinylic monomer and/or at least one polysiloxane vinylic crosslinker, (3) at least one UV-absorbing vinylic monomer, and (4) a least one polymerizable HEVL-absorbing compound capable of absorbing HEVL between 380 nm and 450 nm and also comprises at least one blue-tinting agent and at least one optical brightener distributed therein.
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Patent Agency Ranking
公开(公告)号：US12194699B2
公开(公告)日：2025-01-14
申请号：US17710199
申请日：2022-03-31
Applicant: Alcon Inc.
Inventor： Zahra Bassampour , Chandana Kolluru , Steve Yun Zhang , Junhao Ge , Yang Zheng , Cornelius Daniel Niculas , David Andrew Icenogle , Jing Cheng , Yuan Chang , Augustine Twum Kumi , Michelle Plavnik
Abstract: The invention relates to a method for producing embedded hydrogel contact lenses involving a set of 3-mold halves consisting essentially of: one female lens mold half having a molding surface defining the anterior surface of a contact lens; one male lens mold half having a molding surface defining the posterior surface of the contact lens; and an insert mold half having a molding surface defining one of the front and back surfaces of an insert. One of the lens mold halves is used twice: first with the insert mold half for molding an insert during first curing process and then with the other lens mold half for molding an embedded hydrogel contact lens with the molded insert embedded partially or fully therein during second curing process. The invention also relates to embedded hydrogel contact lenses produced from a method of the invention.
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公开(公告)号：US12194698B2
公开(公告)日：2025-01-14
申请号：US17701819
申请日：2022-03-23
Applicant: Alcon Inc.
Inventor： Richard Charles Breitkopf , Zahra Bassampour , Chandana Kolluru , Steve Yun Zhang
IPC: G02C7/00 , B29C45/14 , B29D11/00 , C08J3/075 , C08J3/24 , G02C7/02 , G02C7/04 , B29C33/38 , B29K83/00 , B29K633/04
Abstract: The invention relates to a method for producing embedded hydrogel contact lenses each having a magnetized insert that comprises magnetic particles and is centrally embedded in the bulk hydrogel material of the embedded hydrogel contact lens. During molding, a magnetized insert can be centered and held in position in a lens mold by using a magnet placed below the lens mold. The invention also relates to an embedded hydrogel contact lens produced from a method of the invention.
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公开(公告)号：US20240399627A1
公开(公告)日：2024-12-05
申请号：US18678872
申请日：2024-05-30
Applicant: Alcon Inc.
Inventor： Ya-Wen Chang , Newton T. Samuel , Steve Yun Zhang , Feng Jing
IPC: B29C39/02 , B29C33/42 , B29C33/56 , B29C39/00 , B29C39/10 , B29C39/26 , B29D11/00 , B29K83/00 , B29K105/00 , B29K105/24 , B29L11/00
Abstract: The invention provides a method for producing embedded contact lenses involving steps of use of a set of 3 mold halves in two-curing steps. One of the 3 mold halves have been used twice, the first time for molding an insert and the second time for molding the embedded hydrogel contact lens. The twice-used mold half has been treated with a corona plasma or a vacuum UV in a central circular area of its molding surface having a diameter equal to or smaller than the diameter of the insert to ensure that the molded insert consistently adhered to the twice-used mold half. The method also comprises a step of forming a reactive polysiloxane coating that is covalently attached onto the back or front surface of a molded insert adhered on the twice-used mold half before molding the embedded contact lens in the 2nd curing step.
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公开(公告)号：US20240254269A1
公开(公告)日：2024-08-01
申请号：US18435562
申请日：2024-02-07
Applicant: Alcon Inc.
Inventor： Jinyu Huang , Frank Chang , Steve Yun Zhang , Feng Jing
IPC: C08F290/06 , C08G77/12 , C08G77/16 , C08G77/20 , C08G77/392 , G02B1/04
CPC classification number: C08F290/068 , C08G77/16 , C08G77/20 , C08G77/392 , G02B1/043 , C08G77/12
Abstract: The invention provides a hydrophilized polydiorganosiloxane vinylic crosslinker which comprises (1) a polydiorganosiloxane polymer chain comprising dimethylsiloxane units and hydrophilized siloxane units each having one methyl substituent and one monovalent C4-C40 organic radical substituent having two to six hydroxyl groups, wherein the molar ratio of the hydrophilized siloxane units to the dimethylsiloxane units is from about 0.035 to about 0.15, and (2) two terminal (meth)acryloyl groups. The hydrophilized polydiorganosiloxane vinylic crosslinker has a number average molecular weight of from about 3000 Daltons to about 80,000 Daltons. The present invention is also related to a silicone hydrogel contact lens, which comprises repeating units derived from a hydrophilized polydiorganosiloxane vinylic crosslinker of the invention.
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公开(公告)号：US11975499B2
公开(公告)日：2024-05-07
申请号：US17518432
申请日：2021-11-03
Applicant: Alcon Inc.
Inventor： Yuan Chang , Junhao Ge , Steve Yun Zhang
CPC classification number: B29D11/00048 , C08F2/48 , G02B1/043
Abstract: Described herein is a method for producing photochromic contact lenses, in particular, photochromic silicone hydrogel contact lenses. The method comprises a step of cast molding of a lens-forming composition including a vinylic monomer having a primary amino or thiolactone group to form an unprocessed contact lens having the polymer matrix of which have pendant primary amino or thiolactone groups, a step of one-pot multistep reactions based on thiolactone chemistry (aminolysis and thiol-induced graft polymerization of a photochromic vinylic monomer to the polymer matrix) which are carried out only in its central region which is circular and concentric with the central axis of the unprocessed contact lens. The obtained photochromic contact lens has a central pupillary region that only can undergo a reversible color change upon exposure to UV/HEVL-radiation.
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