公开(公告)号：US11234772B2

公开(公告)日：2022-02-01

申请号：US16771379

申请日：2018-12-11

Applicant: HOLOGIC, INC.

Inventor： John Laviola ,  Shawn St. Pierre ,  Brian Stellmach ,  Lori Fontaine ,  Joseph A. Stand, III ,  Estefania Alvarez ,  Stephen Grantz ,  Michelle Dawn Lyman ,  Shannon Marie Butler ,  Yuliya Mathis

IPC: A61B34/20 ,  A61B90/00 ,  G06T7/70 ,  A61B5/06 ,  A61B8/08 ,  A61B8/00 ,  A61B17/3211 ,  A61B18/00

Abstract: Disclosed biopsy markers are adapted to serve as localization markers during a surgical procedure. Adaptation includes incorporation of materials detectable under ultrasound during surgery, as well as features for co-registration with image guidance or other real-time imaging technologies during surgery. Such biopsy markers, when used as localization markers, improve patient comfort and reduce challenges in surgical coordination and surgery time. Additional disclosed biopsy markers are adapted to serve as monitoring and/or detection apparatuses. Localization of an implanted marker may be done with ultrasound technology. Ultrasound image data is analyzed to identify the implanted marker. A distance to the marker or a lesion may be determined and displayed. The determined distance may be a distance between the ultrasound probe and the marker or lesion, a distance between the marker or lesion and an incision instrument, and/or a distance between the ultrasound probe and the incision instrument.

公开(公告)号：US11229482B2

公开(公告)日：2022-01-25

申请号：US16192109

申请日：2018-11-15

Applicant: Hologic, Inc.

Inventor： Dan Sachs ,  Edwin J. Hlavka

IPC: A61B18/14 ,  A61B18/04 ,  A61B18/18 ,  A61F7/12 ,  A61B18/24 ,  A61B18/00

Abstract: Apparatus and methods are provided to concentrate energy delivery in non-superficial target tissue within a trigone region of a human bladder wall to modulate bladder function.

公开(公告)号：US11191502B2

公开(公告)日：2021-12-07

申请号：US16720111

申请日：2019-12-19

Applicant: Hologic, Inc.

Inventor： Andrew P. Smith ,  Jay A. Stein ,  Ken Defreitas ,  Ian Shaw ,  Zhenxue Jing ,  Loren Niklason ,  Baorui Ren ,  Christopher Ruth

IPC: A61B6/00 ,  A61B6/02 ,  A61B6/04 ,  A61B6/03

Abstract: A multi-mode system and method for imaging a patient's breast with x-rays in one or more of a CT mode, a narrow-angle tomosynthesis mode, a wide angle tomosynthesis mode, and a mammography mode, using essentially the same equipment, on one or more compressions or immobilizations of the breast.

公开(公告)号：US20210262462A1

公开(公告)日：2021-08-26

申请号：US17317432

申请日：2021-05-11

Applicant: HOLOGIC, INC.

Inventor： Danny Macari ,  Mathew John Whitney

IPC: F04B43/12 ,  F04B43/00 ,  F04B53/16

Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.

公开(公告)号：US11090017B2

公开(公告)日：2021-08-17

申请号：US16567910

申请日：2019-09-11

Applicant: Hologic, Inc.

Inventor： Yiheng Zhang ,  Zhenxue Jing ,  Christopher Ruth

IPC: A61B6/00 ,  A61B6/04 ,  G06T11/00 ,  G06T7/70 ,  G06T7/00 ,  A61B5/00 ,  A61B6/02 ,  G06T5/50

Abstract: Methods and systems for medical imaging including synthesizing virtual projections from acquired real projections and generating reconstruction models and images based on the synthesized virtual projections and acquired real projections. For example, first x-ray imaging data is generated from a detected first x-ray emission at a first angular location and second x-ray imaging data is generated from a detected second x-ray emission at a second angular location. Based on at least the first x-ray imaging data and the second x-ray imaging data, third x-ray imaging data for a third angular location relative to the breast may be synthesized. An image of the breast may be displayed or generated from the third x-ray imaging data.

公开(公告)号：US20210233647A1

公开(公告)日：2021-07-29

申请号：US17228497

申请日：2021-04-12

Applicant: HOLOGIC, INC.

Inventor： Raymond Jenoski ,  Sid Mayer ,  Robert Jennings ,  Ryan P. Oliva ,  John A. McCrorey ,  Michael D. Quick ,  Sarah Margaret Harrington

IPC: G16H30/40 ,  G06F3/0482 ,  G06F3/0484 ,  G06F3/0485 ,  H04N5/232 ,  H04N5/262 ,  G16H10/40 ,  G02B21/36 ,  G02B21/34

Abstract: Automated systems and methods for evaluating specimens affixed to substrates, such as slides, an exemplary system including a slide imager configured for acquiring a plurality of micro images of a specimen affixed to an substrate, the specimen including a plurality of objects distributed within a three-dimensional volume, and for generating a whole specimen image of the specimen using the micro images, wherein objects contained in the specimen are depicted substantially in focus in the whole specimen image regardless of a z-depth of the respective objects within the specimen. The whole specimen image is stored on a storage medium for subsequent review by a cytotechnologist using a computer-controlled review station including a display and a user interface, wherein the review station user interface is configured such that the cytotechnologist can review and classify the stored whole specimen images.

公开(公告)号：US11058380B2

公开(公告)日：2021-07-13

申请号：US16670871

申请日：2019-10-31

Applicant: HOLOGIC, INC.

Inventor： Kevin Wilson ,  Thomas Kelly

IPC: A61B6/00 ,  G06T7/00

Abstract: A system for measuring muscle mass of a patient has a dual-energy radiation emission source. A radiation detector is configured to detect radiation emitted from the dual-energy radiation emission source passed through the patient. A processor has a memory with storing instructions, that when executed by the processor, perform a set of operations. The operations include receiving radiation detection data; generating a scan representation; identifying a primary fat target; determining an amount of fat in the primary fat target; comparing the amount of fat in the primary fat target to a reference; and based on the comparison, correcting an estimated amount of lean tissue to generate a corrected muscle mass value.

公开(公告)号：US20210177368A1

公开(公告)日：2021-06-17

申请号：US17183548

申请日：2021-02-24

Applicant: Hologic, Inc.

Inventor： Kevin Wilson

IPC: A61B6/00

Abstract: A method includes moving a radiation source and a radiation detector along a scan path substantially transverse to a longitudinal axis of a patient. A beam of radiation is emitted from the radiation source. The beam of radiation is detected at the radiation detector. The detected beam is processed so as to form a first image of a first area of the patient along the scan path.

公开(公告)号：US20210100538A1

公开(公告)日：2021-04-08

申请号：US17079195

申请日：2020-10-23

Applicant: HOLOGIC, INC.

Inventor： Peter Wolton ,  Daniel Robertson ,  Thomas Fisk ,  Joseph A. Stand, III ,  Christian M. Ulm ,  Carl Pierce

IPC: A61B10/02

Abstract: A biopsy device includes an instrument set and an instrument drive unit removably coupled to the instrument set. The instrument set includes an instrument set housing; an elongate outer cannula having a tissue receiving aperture in a side wall thereof; an elongate inner cannula disposed within an outer cannula lumen; an aspiration vent fluidly coupling the outer cannula lumen to atmosphere; and an aspirate valve in the aspiration vent, and configured such that the outer cannula lumen is vented to atmosphere only when the aspirate valve is open. The instrument drive unit includes a drive unit support structure removably coupled to the instrument set housing; a motorized inner cannula driver configured to axially oscillate the inner cannula relative to the outer cannula to sever tissue extending through the tissue receiving opening; and an actuating member configured to selectively mechanically prevent the aspirate valve from closing.

公开(公告)号：US20210098120A1

公开(公告)日：2021-04-01

申请号：US17033372

申请日：2020-09-25

Applicant: Hologic, Inc.

Inventor： Ashwini KSHIRSAGAR ,  Haili CHUI ,  Nikolaos GKANATSIOS ,  Adora DSOUZA ,  Xiangwei ZHANG

IPC: G16H40/20 ,  G06T7/00 ,  G16H30/20 ,  G16H30/40 ,  G16H50/20 ,  G16H50/30 ,  G16H10/20 ,  G06Q10/06 ,  G06Q10/10

Abstract: Examples of the present disclosure describe systems and methods for predicting the reading time and/or reading complexity of a breast image. In aspects, a first set of data relating to the reading time of breast images may be collected from one or more data sources, such as image acquisition workstations, image review workstations, and healthcare professional profile data. The first set of data may be used to train a predictive model to predict/estimate an expected reading time and/or an expected reading complexity for various breast images. Subsequently, a second set of data comprising at least one breast image may be provided as input to the trained predictive model. The trained predictive model may output an estimated reading time and/or reading complexity for the breast image. The output of the trained predictive model may be used to prioritize mammographic studies or optimize the utilization of available time for radiologists.