公开(公告)号：US06760104B2

公开(公告)日：2004-07-06

申请号：US09910036

申请日：2001-07-20

申请人： Grigoriy Gomelskiy

发明人： Grigoriy Gomelskiy

IPC分类号： G01J330

CPC分类号： G01N21/70

摘要： An apparatus, method, and system are disclosed to analyze samples materials using triboluminescent technology. A mechanical activation knot is provided that comprises an optical window, a membrane, and a device that supplies a constant pressure of gas on the zone of activation. A sample is placed between the membrane and the optical window. The optical window is rotated along its z-axis. The friction between the sample and the optical window generates triboluminescence and associated optical emissions. Optical emissions may be distributed on the spectrum by a spectrograph, a monochromator, or a collection of filters, and then fixed by the charge coupled device, a photodiode, or a photomultiplier tube. Then, the results (data) are incorporated into different mathematical algorithms or programs with the help of computers or other computation technologies. The final results (the output) may be compared among themselves or with reference data stored in a computer's memory.

摘要翻译： 公开了一种使用三重发光技术分析样品材料的装置，方法和系统。 提供了机械激活结，其包括光学窗口，膜和在激活区域上提供恒定气体压力的装置。 将样品放置在膜和光学窗口之间。 光学窗口沿其z轴旋转。 样品与光学窗口之间的摩擦产生三次发光和相关的光学发射。 光发射可以通过光谱仪，单色仪或滤光片的集合在光谱上分布，然后由电荷耦合器件，光电二极管或光电倍增管固定。 然后，结果（数据）通过计算机或其他计算技术的帮助被并入到不同的数学算法或程序中。 最终结果（输出）可以在它们之间或存储在计算机的存储器中的参考数据进行比较。

公开(公告)号：US06741346B1

公开(公告)日：2004-05-25

申请号：US09869317

申请日：2001-12-21

申请人： Volker Gerstner ,  Ralf Wolleschensky

发明人： Volker Gerstner ,  Ralf Wolleschensky

IPC分类号： G01J330

CPC分类号： G01N21/6408

摘要： Process for detecting the phenomenon of fluorescence in a microscope, wherein the sample is irradiated by a modulated and/or pulsed laser light source, and the fluorescence is detected at least in two different phase positions of the detector.

摘要翻译： 用于在显微镜中检测荧光现象的方法，其中样品被调制和/或脉冲激光光源照射，并且在检测器的至少两个不同的相位位置检测荧光。

公开(公告)号：US06741345B2

公开(公告)日：2004-05-25

申请号：US09778723

申请日：2001-02-08

申请人： Mohamad Sabsabi ,  René Héon ,  John M. Lucas

发明人： Mohamad Sabsabi ,  René Héon ,  John M. Lucas

IPC分类号： G01J330

CPC分类号： G01N21/718 ,  G01N21/15 ,  G01N21/85

摘要： A method and apparatus for spectrochemical analysis of liquids, including molten metals, using laser-induced plasma spectroscopy. The apparatus preferably comprises a high power pulsed laser focused on the surface of a liquid stream flowing in a measurement cell, and an optical spectrometer-detector assembly, which receives, detects and analyzes the radiation emitted by the high temperature plasma thereby excited. The measurement cell, and optional pump, establish laminar flow of the liquid flow, thereby permitting the laser to repeatedly sample a fresh un-perturbed surface, while also ensuring that bubbles formed in the liquid are removed from the focal volume Preferably, a blower prevents aerosols and matter ejected from the sample responsive to the incident energy from interacting with subsequent laser pulses, and from accumulating on the optic.

摘要翻译： 使用激光诱导等离子体光谱法对包括熔融金属在内的液体进行光谱化学分析的方法和装置。 该装置优选地包括聚焦在在测量单元中流动的液体流的表面上的高功率脉冲激光器和接收，检测和分析由此被激发的高温等离子体发射的辐射的光谱仪检测器组件。 测量单元和可选的泵建立液体流的层流，从而允许激光器重复地对新鲜的未受扰动的表面进行采样，同时还确保从聚焦体积中除去形成在液体中的气泡。优选地，鼓风机防止 响应于入射能量与随后的激光脉冲相互作用而从样品喷射的气溶胶和物质，以及积聚在光学元件上。

公开(公告)号：US06707043B2

公开(公告)日：2004-03-16

申请号：US10201184

申请日：2002-07-22

申请人： John Coates ,  Neil Rosenbaum ,  Yosef Abuneaj

发明人： John Coates ,  Neil Rosenbaum ,  Yosef Abuneaj

IPC分类号： G01J330

CPC分类号： G01N33/30 ,  G01J3/28 ,  G01J3/443 ,  G01N21/274 ,  G01N21/3577 ,  G01N21/67 ,  G01N21/69 ,  G01N33/2847 ,  G01N33/2858 ,  G01N33/2888

摘要： An apparatus (10) for analyzing lubricant oils and functional fluids includes an optical emission spectrometer (OES) (26) having a substantially continuously valued wavelength versus intensity output (140). The OES (26) analyzes light captured from a spark emission stand (58) through which the fluid sample is flowed. An expert system (160-172) operates according to a set of Rules, and generates diagnostic text (174) for an operator based on the information about the fluid sample provided by the OES (26) and other measurement devices. The apparatus (10) is reduce in size, weight and cost.

摘要翻译： 用于分析润滑油和功能流体的装置（10）包括具有基本上连续值的波长对强度输出（140）的光发射光谱仪（OES）（26）。 OES（26）分析从流体样品流过的火花发射台（58）捕获的光。 专家系统（160-172）根据一组规则操作，并且基于由OES（26）和其他测量装置提供的关于流体样本的信息，为操作者生成诊断文本（174）。 装置（10）的尺寸，重量和成本都降低。

公开(公告)号：US06700660B2

公开(公告)日：2004-03-02

申请号：US10071529

申请日：2002-02-08

申请人： Mohamad Sabsabi ,  Rene Heon ,  John M. Lucas

发明人： Mohamad Sabsabi ,  Rene Heon ,  John M. Lucas

IPC分类号： G01J330

CPC分类号： G01N21/718 ,  G01N21/15 ,  G01N21/85

摘要： A method and apparatus for spectrochemical analysis of liquids, including molten materials, using laser-induced plasma spectroscopy. The apparatus preferably comprises a high power pulsed laser focused on the surface of a liquid stream flowing in a measurement cell, and an optical spectrometer-detector assembly, which receives, detects and analyzes the radiation emitted by the high temperature plasma thereby excited. The measurement cell, and optional pump, establish a steady flow of liquid, thereby permitting the laser to repeatedly sample a fresh unperturbed surface, representative of the liquid volume, while also ensuring that bubbles and waves formed in the liquid are removed from the focal volume. Gas (usually air) blown above the liquid prevents aerosols and matter ejected from the sample responsive to the incident energy from interacting with subsequent laser pulses, and from accumulating on the optics.

摘要翻译： 使用激光诱导等离子体光谱法对包括熔融材料在内的液体进行光谱化学分析的方法和装置。 该装置优选地包括聚焦在在测量单元中流动的液体流的表面上的高功率脉冲激光器和接收，检测和分析由此被激发的高温等离子体发射的辐射的光谱仪检测器组件。 测量单元和可选的泵建立稳定的液体流动，从而允许激光器重复地采样代表液体体积的新鲜的不受干扰的表面，同时还确保液体中形成的气泡和波从焦点体积中移除 。 响应于入射能量与随后的激光脉冲相互作用并从积累在光学器件上的气体（通常是空气）防止从液体喷射的气溶胶和物质。

公开(公告)号：US06690463B2

公开(公告)日：2004-02-10

申请号：US09779704

申请日：2001-02-09

申请人： Peet Kask

发明人： Peet Kask

IPC分类号： G01J330

CPC分类号： G01N21/6458 ,  G01J3/4406 ,  G01N21/6408 ,  G01N21/6445 ,  G01N2015/0216

摘要： The present invention relates to a method for characterizing samples having fluorescent particles, comprising the steps of: exciting particles in a measurement volume to emit fluorescence by a series of excitation pulses, monitoring the emitted fluorescence by detecting sequences of photon counts using a detector, determining numbers of photon counts in counting time intervals of given width, determining in the counting time intervals detection delay times of the photon counts relative to the corresponding excitation pulses, determining a function of the detection delay times, determining a probability function of at least two arguments, {circumflex over (P)}(n, t, . . . ), wherein at least one argument is the number of photon counts and another argument is the function of detection delay times, and determining from the probability function {circumflex over (P)}(n, t, . . . ) a distribution of particles as a function of at least two arguments, wherein one argument is a specific brightness of the particles, or a measure thereof, and another argument is a fluorescence lifetime of the particles, or a measure thereof.

摘要翻译： 本发明涉及一种用于表征具有荧光颗粒的样品的方法，包括以下步骤：激发测量体积中的颗粒以通过一系列激发脉冲发射荧光，通过使用检测器检测光子计数序列来监测发射的荧光，确定 在给定宽度的计数时间间隔中的光子计数的数量，在计数时间间隔中确定光子计数相对于相应的激励脉冲的检测延迟时间，确定检测延迟时间的函数，确定至少两个参数的概率函数 ，P（n，t，...），其中至少一个参数是光子计数的数量，另一个参数是检测延迟时间的函数，并且从概率函数P（n，t，...）a 作为至少两个参数的函数的粒子的分布，其中一个参数是粒子的特定亮度或其度量，以及 另一个观点是颗粒的荧光寿命或其测量。

公开(公告)号：US06686999B2

公开(公告)日：2004-02-03

申请号：US10020559

申请日：2001-12-14

申请人： Suhas Narayan Ketkar

发明人： Suhas Narayan Ketkar

IPC分类号： G01J330

CPC分类号： G01N21/278 ,  G01N21/73

摘要： Using a nebulizer gas, sub micron and micron size particulates can be generated from a solution containing salts covering a broad range of elements. The fractional concentration of elements can be determined by bubbling the aerosol through aqueous acid and analyzing the aqueous acid for metals. The nebulizer can be coupled to an ICP (Inductively Coupled Plasma) torch and the ICPMS (Inductively Coupled Plasma Mass Spectrometer) or ICPOES (Inductively Coupled Plasma Optical Emission Spectrometer) response to different elements can be determined. This provides the response factor of the ICPMS or ICPOES for different elements.

摘要翻译： 使用雾化器气体，亚微米和微米尺寸的颗粒可以由含有宽范围元素的盐的溶液产生。 元素的分数浓度可以通过使气溶胶鼓泡通过含水酸并分析含水酸的金属来确定。 喷雾器可以耦合到ICP（电感耦合等离子体）手电筒，并且可以确定对不同元件的ICPMS（电感耦合等离子体质谱仪）或ICPOES（电感耦合等离子体发射光谱仪）响应。 这为不同元素提供了ICPMS或ICPOES的响应因子。

公开(公告)号：US06661510B1

公开(公告)日：2003-12-09

申请号：US09743511

申请日：2001-01-11

申请人： Anders Hanning ,  Johan Roeraade

发明人： Anders Hanning ,  Johan Roeraade

IPC分类号： G01J330

CPC分类号： G01N21/6456 ,  G01N21/0303

摘要： A device for detection of one or several fluorescent species, said species being contained in a medium, said medium being contained in a conduit, said device comprising a means of exciting the fluorescent species by light, said medium and conduit making up a structure that is transparent to the exciting and the emitted fluorescent light, and said device comprising one or several such structures, may be improved by letting at least part of the emitted fluorescent light be guided away from the illumination zone by total internal reflection (TIR) in said structure and collected from one end of said structure.

摘要翻译： 一种用于检测一种或多种荧光物质的装置，所述物质包含在介质中，所述介质包含在导管中，所述装置包括通过光激发荧光物质的装置，所述介质和导管构成结构， 对于激发和发射的荧光是透明的，并且包括一个或多个这样的结构的所述装置可以通过使至少部分发射的荧光通过所述结构中的全内反射（TIR）被引导离开照明区域来改进 并从所述结构的一端收集。

公开(公告)号：US06643015B2

公开(公告)日：2003-11-04

申请号：US09683219

申请日：2001-12-03

申请人： Nathan K. Weiner

发明人： Nathan K. Weiner

IPC分类号： G01J330

CPC分类号： G01N21/6428 ,  B01J2219/00675 ,  B01J2219/00677 ,  B82Y30/00 ,  B82Y35/00 ,  C40B50/14 ,  G01N21/6452 ,  G01N21/6456 ,  G01N27/44717 ,  G01N27/44721 ,  G01N2035/00158 ,  G01N2035/0494 ,  G06F19/20

摘要： An apparatus is described that includes an emission signal detector and an emission signal filter. An excitation beam scans an array of biological materials, and the emission signal detector detects an emission signal indicative of an emission beam responsive to the excitation beam. The emission signal filter is a linear-phase filter that provides a filtered emission signal having substantially symmetrical rise and fall edges. A linear-phase excitation signal filter may also be provided that provides a filtered excitation signal having substantially symmetrical rise and fall edges. The emission signal filter and the excitation signal filter may be matched. In some applications, they may be high-order Bessel filters. Linear-phase filtering enables sampling of emission signals to be accomplished consistently irrespective of the scanning direction, and thus is particularly advantageous in bi-directional scanning applications.

公开(公告)号：US06597450B1

公开(公告)日：2003-07-22

申请号：US09483686

申请日：2000-01-14

申请人： Jeffrey P. Andrews ,  Christian V. O'Keefe ,  Brian G. Scrivens ,  Willard C. Pope ,  Timothy Hansen ,  Frank L. Failing

发明人： Jeffrey P. Andrews ,  Christian V. O'Keefe ,  Brian G. Scrivens ,  Willard C. Pope ,  Timothy Hansen ,  Frank L. Failing

IPC分类号： G01J330

CPC分类号： G01N21/6452 ,  G01N21/64 ,  G01N35/028 ,  G01N2021/6419 ,  G01N2021/6484

摘要： An apparatus and method employing a plurality of light emitting devices which each can get light through a respective optical fiber toward a respective sample of a plurality of samples in a time-staggered manner. Light is generated in each of the samples at different times consistent with the times at which light is irradiated onto the sample. A single detector is used to detect the lights emitted from the plurality of samples at these different times. A plurality of bifurcated optical cable are coupled to the light emitting devices and single light detector, and the integrated end of each bifurcated cable acts as the light emitting port and light detecting port. Multiple targets can be detected from each of the plurality of samples in the same manner by providing an apparatus and method employing a different plurality of light emitting devices and single detector for each target to be detected.

摘要翻译： 一种使用多个发光器件的装置和方法，每个发光器件可以通过相应的光纤以时间交错的方式朝向多个样本的相应样本获得光。 在与照射到样品上的时间一致的不同时间，在每个样品中产生光。 单个检测器用于检测在这些不同时间从多个样品发射的光。 多个分叉光缆耦合到发光器件和单个光检测器，并且每个分叉电缆的集成端用作发光端口和光检测端口。 可以以相同的方式从多个样本中的每一个检测多个目标，方法是提供使用不同的多个发光装置的装置和方法以及用于每个要检测的目标的单个检测器。