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    Antiparasitic agent for fish and method of controlling proliferation of fish parasites
    54.
    发明授权
    Antiparasitic agent for fish and method of controlling proliferation of fish parasites 有权
    鱼类抗寄生虫药物及控制鱼类寄生虫增殖的方法

    公开(公告)号：US09265777B2

    公开(公告)日：2016-02-23

    申请号：US13258814

    申请日：2010-04-26

    申请人： Fumi Kawano ,  Noritaka Hirazawa

    发明人： Fumi Kawano ,  Noritaka Hirazawa

    IPC分类号： A61P33/02 ,  A61K31/433 ,  A61K31/42 ,  A61K31/635 ,  A61K31/505 ,  A61K31/519 ,  A61K45/06

    CPC分类号： A61K31/635 ,  A61K31/42 ,  A61K31/433 ,  A61K31/505 ,  A61K31/519 ,  A61K45/06 ,  A61K2300/00

    摘要： A method of controlling proliferation of fish parasites comprising the administration of 1 to 50 mg/kg fish body weight/day of an inhibitor of folate synthesis and/or an inhibitor of folate activation to fish continuously for 1 to 2 weeks. Using a combination preparation composed of an inhibitor of folate synthesis and an inhibitor of folate activation is preferable, and a sulfonamide is preferable for the inhibitor of folate synthesis. A dihydrofolate reductase inhibitor, a folate antagonist, etc., can be used as the inhibitor of folate activation. The antiparasitic agent is able to exterminate fish parasites via oral administration. It is particularly effective against parasites belonging to the ciliate group among fish parasites.

    摘要翻译： 一种控制鱼类寄生虫增殖的方法，其包括向鱼连续施用1至50mg / kg鱼体重/天的叶酸合成抑制剂和/或叶酸活化抑制剂1至2周。 使用由叶酸合成抑制剂和叶酸活化抑制剂组成的组合制剂是优选的，磺酰胺优选用于叶酸合成抑制剂。 二氢叶酸还原酶抑制剂，叶酸拮抗剂等可用作叶酸活化的抑制剂。 抗寄生虫剂能够通过口服给药消灭鱼类寄生虫。 对于属于鱼类寄生虫中的细胞组的寄生虫特别有效。

    Salty taste enhancer and food or drink containing same
    57.
    发明授权
    Salty taste enhancer and food or drink containing same 有权
    咸味增强剂和含有其的食物或饮料

    公开(公告)号：US08932661B2

    公开(公告)日：2015-01-13

    申请号：US12934028

    申请日：2009-03-23

    申请人： Masashi Shimono ,  Kiminori Sugiyama

    发明人： Masashi Shimono ,  Kiminori Sugiyama

    IPC分类号： A23L1/227 ,  A23L1/237 ,  A23L1/22 ,  A23L1/325

    CPC分类号： A23L1/237 ,  A23L17/65 ,  A23L17/70 ,  A23L27/40 ,  A23L27/88

    摘要： It is possible to provide an excellent salty taste enhancer is provided that can compensate for insufficient salty taste when attempting to reduce salt content in a food. A salty taste enhancer consisting of a mixture of an enzymatic decomposition product of an animal protein and an enzymatic decomposition product of a plant protein. A salty taste enhancer in which the enzymatic decomposition products are treated with a protein-hydrolyzing enzyme and/or a nucleic acid-hydrolyzing enzyme. A salty taste enhancer in which the animal protein is a fish or shellfish extract and the plant protein is a soy bean protein. A salty taste enhancer in which a basic amino acid, and especially arginine, is further added to the salty taste enhancer. A salty taste enhancer to which potassium chloride is further added. A salty taste enhancer obtained by rendering the salty taste enhancer mildly acidic. A method for producing these salty taste enhancers, a method for enhancing a salty taste by using these salty taste enhancers, and a food or drink that contains these salty taste enhancers.

    摘要翻译： 可以提供优异的咸味增强剂，其可以在尝试减少食物中的盐含量时补偿不足的咸味。 一种由动物蛋白的酶分解产物和植物蛋白的酶分解产物的混合物组成的咸味增强剂。 一种咸味增强剂，其中酶分解产物用蛋白质水解酶和/或核酸水解酶处理。 一种咸味增强剂，其中动物蛋白质是鱼或贝类提取物，植物蛋白质是大豆蛋白质。 其中进一步向咸味增强剂中加入碱性氨基酸，特别是精氨酸的咸味增强剂。 进一步添加氯化钾的咸味增强剂。 通过使咸味增强剂呈弱酸性而得到的咸味增强剂。 制造这些咸味增强剂的方法，通过使用这些咸味增强剂来提高咸味的方法，以及含有这些咸味增强剂的食品或饮料。

    Method for increasing the content of docosahexaenoic acid in fat-containing materials or in fats and oils
    60.
    发明授权
    Method for increasing the content of docosahexaenoic acid in fat-containing materials or in fats and oils 失效
    增加含脂肪物质或脂肪和油中二十二碳六烯酸含量的方法

    公开(公告)号：US08349595B2

    公开(公告)日：2013-01-08

    申请号：US12524647

    申请日：2008-01-25

    申请人： Masahiro Hayashi ,  Sanae Nakajima ,  Naoki Nagano ,  Yosuke Taoka

    发明人： Masahiro Hayashi ,  Sanae Nakajima ,  Naoki Nagano ,  Yosuke Taoka

    IPC分类号： C12P7/64 ,  C12N1/12 ,  C07C57/03

    CPC分类号： C12P7/6427 ,  C11C3/00 ,  C12N1/14 ,  C12P7/6472

    摘要： [PROBLEMS] To provide a fat-and-oil in which the content of docosahexaenoic acid is increased.[MEANS FOR SOLVING PROBLEMS] A process for producing highly unsaturated fatty acids comprising culturing a stramenopile capable of producing highly unsaturated fatty acids in a culture medium containing an inhibitor for fatty acid desaturases; fats-and-oils in which the content of highly unsaturated fatty acids, particularly docosahexaenoic acid produced by the relevant method, is increased. A method for enhancing the productivity of highly unsaturated fatty acids in stramenopiles, comprising culturing a stramenopile in a culture medium containing an inhibitor for fatty acid desaturases; stramenopiles having the enhanced productivity of highly unsaturated fatty acids, generated by the relevant method. Particularly, the process for producing highly unsaturated fatty acids, the method for enhancing the productivity of highly unsaturated fatty acids, and the stramenopile having the enhanced productivity of highly unsaturated fatty acids, wherein the stramenopile is a microorganism classified into Labyrinthulea.

    摘要翻译： [问题]提供其中二十二碳六烯酸含量增加的脂肪和油。 解决问题的手段一种高不饱和脂肪酸的制造方法，其特征在于，在含有脂肪酸去饱和酶抑制剂的培养基中培养能够生产高度不饱和脂肪酸的前列腺素; 其中通过相关方法生产的高度不饱和脂肪酸，特别是二十二碳六烯酸的含量增加的脂肪和油。 一种增强层状高分子量不饱和脂肪酸的生产率的方法，包括在含有脂肪酸去饱和酶抑制剂的培养基中培养前列腺素; 具有通过相关方法生成的高度不饱和脂肪酸的生产率提高的前列腺素。 特别是生产高不饱和脂肪酸的方法，提高高不饱和脂肪酸的生产率的方法以及具有提高的高度不饱和脂肪酸的生产率的前列腺素，其中所述地釉菌是分类为迷迭虫的微生物。