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公开(公告)号：US12104139B2
公开(公告)日：2024-10-01
申请号：US16563260
申请日：2019-09-06
Applicant: DSM IP ASSETS B.V.
Inventor： Neil Francis Leininger , Ginger Shank , Xiao Dong , Joseph William Pfeifer, III , Vidya Pai
IPC: C11B1/02 , C07C51/42 , C07C51/487 , C11B3/00
CPC classification number: C11B1/02 , C07C51/42 , C07C51/487 , C11B1/025 , C11B3/001 , C07C51/487 , C07C57/03 , C07C51/42 , C07C57/03
Abstract: Disclosed herein are processes for obtaining a microbial oil comprising one or more polyunsaturated fatty acids (PUFAs) from one or more microbial cells by lysing the cells to form a lysed cell composition, treating the lysed cell composition to form an oil-containing emulsion and then recovering the oil from the oil-containing emulsion. Further disclosed herein is microbial oil comprising one or more PUFAs that is recovered from microbial cells by at least one process described herein.
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公开(公告)号：US11946017B2
公开(公告)日：2024-04-02
申请号：US16317305
申请日：2017-07-12
Applicant: Evonik Operations GmbH , DSM IP Assets B.V.
Inventor： Manfred Bärz , Marc Beiser , Georg Borchers , Stephen Robert Cherinko , Mathias Dernedde , Michael Diehl , Xiao Daniel Dong , Jürgen Haberland , Michael Benjamin Johnson , Robert Cody Kertis , Jochen Lebert , Neil Francis Leininger , Kirt Lyvell Matthews, Sr. , Holger Pfeifer , Christian Rabe , Shannon Elizabeth Ethier Resop , Ginger Marie Shank , Vinod Tarwade , David Allen Tinsley , Daniel Verkoeijen
IPC: C11B1/12 , A23K10/12 , A23K20/158 , C11B1/02
CPC classification number: C11B1/12 , A23K10/12 , A23K20/158 , C11B1/025
Abstract: The current invention relates to a method of separating polyunsaturated fatty acids containing lipids from a lipids containing biomass.
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公开(公告)号：US20190249108A1
公开(公告)日：2019-08-15
申请号：US16309632
申请日：2017-07-12
Applicant: Stephen Robert CHERINKO , Matthias DERNEDDE , Xiao Daniel DONG , Michael Benjamin JOHNSON , Robert Cody KERTIS , Jochen LEBERT , Neil Francis LEININGER , Kirt Lyvell MATTHEWS , Holger PFEIFER , Horst PRIEFERT , Christian RABE , Shannon Elizabeth Ethier RESOP , Joachim WINDAU , Daniel VERKOEIJEN , Gabriel ZAVODSKY , DSM IP Assets B.V. , Evonik Degussa GmbH
Inventor： Stephen Robert CHERINKO , Matthias DERNEDDE , Michael DIEHL , Xiao Daniel DONG , Michael Benjamin JOHNSON , Robert Cody KERTIS , Jochen LEBERT , Neil Francis LEININGER , Kirt Lyvell MATTHEWS , Holger PFEIFER , Horst PRIEFERT , Christian RABE , Shannon Elizabeth Ethier RESOP , Joachim WINDAU , Daniel VERKOEIJEN , Gabriel ZAVODSKY
CPC classification number: C11B1/10 , A23K10/12 , A23K20/158 , C07C51/48 , C11B1/02 , C11B1/025 , C11B1/14 , C11B3/16 , C12N1/06 , C12P7/6427 , C12P7/6472 , C07C57/02
Abstract: The processes for obtaining a microbial oil comprising one or more polyunsaturated fatty acids (PUFAs) from one or more microbial cells comprise removing water from the cell fermentation broth or lysed cell composition before demulsification is conducted. Such a process has the benefits of reduced demulsification time and reduced salt use. Microbial oil comprising one or more PUFAs can be recovered from microbial cells by the process.
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4.发明申请公开(公告)号：US20190136273A1
公开(公告)日：2019-05-09
申请号：US16186316
申请日：2018-11-09
Applicant: Corbion Biotech, Inc.
Inventor： Scott Franklin , Walter Rakitsky , George Rudenko , Xinhua Zhao , Felipe Arana Rodriguez , Wenhua Lu , Janice Wee
IPC: C12P7/64 , C11B1/02 , C11B1/06 , C11B1/10 , C11B3/00 , C11B3/06 , C11B3/10 , C11B3/14 , H01B3/20 , A23D9/02 , C12N9/42 , C12N15/79 , H01F27/32 , C10M169/04 , A23D9/007 , H01F27/10
CPC classification number: C12P7/6463 , A23D9/007 , A23D9/02 , C10M169/041 , C11B1/025 , C11B1/06 , C11B1/10 , C11B3/001 , C11B3/006 , C11B3/008 , C11B3/06 , C11B3/10 , C11B3/14 , C12N9/16 , C12N9/2442 , C12N15/79 , C12P7/64 , C12P7/6409 , C12Y301/02014 , H01B3/20 , H01F27/105 , H01F27/321
Abstract: Methods and compositions for the production of dielectric fluids from lipids produced by microorganisms are provided, including oil-bearing microorganisms and methods of low cost cultivation of such microorganisms. Microalgal cells containing exogenous genes encoding, for example, a sucrose transporter, a sucrose invertase, a fructokinase, a polysaccharide-degrading enzyme, a lipid pathway modification enzyme, a fatty acyl-ACP thioesterase, a desaturase, a fatty acyl-CoA/aldehyde reductase, and/or an acyl carrier protein are useful in manufacturing dielectric fluids.
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公开(公告)号：US09777243B2
公开(公告)日：2017-10-03
申请号：US14595526
申请日：2015-01-13
Applicant: The United States of America, as Represented by the Secretary of Agriculture , Dupont Industrial Bioscience
Inventor： Robert A. Moreau , David Johnston , Kevin B. Hicks , Jayarama K. Shetty
Abstract: Methods for obtaining corn oil from milled corn germ (e.g., dry milled corn germ), involving adding water, at least one acidic cellulase, at least one acidic protease, and at least one phytase to milled corn germ to obtain corn oil.
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Patent Agency Ranking
6.发明授权公开(公告)号：US09732302B2
公开(公告)日：2017-08-15
申请号：US13377353
申请日：2011-12-05
Applicant: Chie Ying Lee
Inventor： Chie Ying Lee
IPC: C11B1/02 , C12F3/00 , C12P7/06 , C12M1/00 , C12M1/33 , A23J1/12 , C11B1/06 , A23K10/38 , A23K50/10 , B01D21/26
CPC classification number: C11B1/02 , A23J1/12 , A23K10/38 , A23K50/10 , B01D21/26 , C11B1/025 , C11B1/06 , C12F3/00 , C12M21/12 , C12M43/02 , C12M45/02 , C12M45/04 , C12M45/20 , C12M47/14 , C12P7/06 , Y02E50/17 , Y02P60/873
Abstract: Systems and methods are provided for separating high value by-products, such as oil and/or germ, from grains used for alcohol production. In one embodiment, a method for separating by-products from grains used for alcohol production includes, subjecting milled grains to liquefaction to provide a liquefied starch solution including fiber, protein, and germ. The germ is separated from the liquefied starch solution. The separated germ is ground, e.g., to a particle size less than 50 microns, to release oil to provide a germ/oil mixture. Then, prior to fermentation, the oil is separated from the germ/oil mixture to yield an oil by-product. The pH of the germ/oil mixture can be adjusted to about 8 to about 10.5 and/or cell wall breaking enzymes or chemicals may be added to help release oil from the germ. In one example, the oil yield is greater than 1.0 lb/Bu.
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公开(公告)号：US20170211012A1
公开(公告)日：2017-07-27
申请号：US15118338
申请日：2015-02-17
Applicant: University of Maryland, Baltimore
Inventor： Robert ERNST , David GOODLETT , Daniel POWELL
Abstract: Improved methods for extracting lipid-containing molecules from microbes are disclosed. The methods utilize selected surfactants for extraction of lipids and lipopolysaccharides from microbes, such as bacteria and fungi. The extracted lipids and lipopolysaccharides may be used, for example, to identify the source microbe via mass spectroscopy.
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公开(公告)号：US09657319B2
公开(公告)日：2017-05-23
申请号：US13917488
申请日：2013-06-13
Applicant: Christopher L. G. Dayton
Inventor： Christopher L. G. Dayton
CPC classification number: C12P7/6418 , C11B1/025 , C11B3/003 , C11C1/045
Abstract: Provided here is an enzymatic process for production of low saturate oil, in one embodiment, low palmitic oils from triacylglycerol sources. The enzymes used in the processes herein are saturase enzymes, including palmitase enzymes. The oils produced by the processes herein are used in food products.
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公开(公告)号：US20160355749A1
公开(公告)日：2016-12-08
申请号：US15106752
申请日：2014-12-18
Applicant: Kirk APT , William BARCLAY , Micah BLAZER , Jacob BORDEN , Adam BURJA , Daniel Dong , Armando DURAZO , Jean-Charles DUMENIL , Arthur EDGE , Jon HANSEN , Alexandra HOFLER , David JEFFERS , Chris LYON , Vidya PAI , Joseph William PFEIFER, III , Martin J. SELLERS , Ginger SHANK , Justin STEGE
Inventor： Kirk APT , William BARCLAY , Micah BLAZER , Jacob BORDEN , Adam BURJA , Daniel Dong , Armando DURAZO , Jean-Charles DUMENIL , Arthur EDGE , Jon HANSEN , Alexandra HOFLER , David JEFFERS , Chris LYON , Vidya PAI , Joseph William PFEIFER, III , Martin J. SELLERS , Ginger SHANK , Justin STEGE
CPC classification number: C11B1/025 , C10L1/02 , C10L2200/0469 , C10L2290/26 , C11B1/10 , C11B1/12 , C12N1/063 , C12N1/066 , C12N9/2411 , C12N9/2414 , C12N9/2488 , C12P7/6463 , C12Y302/01001 , Y02E50/343
Abstract: Methods and systems used to extract lipids suitable in production of biofuels from a fermentation broth may include using heat to pre-treat the fermentation broth in order to more easily extract a product from oleaginous microorganisms in the broth. Additionally or alternatively, a combination of enzymes including amylase, 1-4 mannosidase, and 1-3 mannosidase may be used to break down cell walls of the oleaginous microorganisms. Residual broth water may be recycled and used as imbibition water for washing a process feedstock to extract sugar.
Abstract translation: 用于提取适合于从发酵液生产生物燃料的脂质的方法和系统可包括使用热来预处理发酵液，以便更容易地从肉汤中的含油微生物中提取产物。 另外或替代地，可以使用包括淀粉酶，1-4甘露糖苷酶和1-3甘露糖苷酶的酶的组合来分解含油微生物的细胞壁。 残余肉汤水可以循环使用，并用作洗涤水以洗涤工艺原料以提取糖。
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公开(公告)号：US20160317485A1
公开(公告)日：2016-11-03
申请号：US15106365
申请日：2014-12-19
Applicant: Mark BARKER , Nasrin TABAYEHNEJAD , Ginger SHANK , Neil LEININGER , Kirt Lyvell MATTHEWS, Sr.
Inventor： Mark BARKER , Nasrin TABAYEHNEJAD , Ginger SHANK , Neil LEININGER , Kirt Lyvell MATTHEWS, Sr.
IPC: A61K31/202 , C11B3/04 , C11B1/02
CPC classification number: A61K31/202 , A23L33/115 , C11B1/025 , C11B1/108 , C11B3/04
Abstract: The present invention relates to processes for obtaining a lipid from a cell by lysing the cell to form a lysed cell composition and obtaining the lipid from the demulsified lysed cell composition. The invention is also directed to a lipid prepared by the processes of the present invention. The invention is also directed to microbial lipids having a particular anisidine value, peroxide value, and/or phosphorus content.
Abstract translation: 本发明涉及通过裂解细胞以形成裂解的细胞组合物并从破乳裂解的细胞组合物获得脂质从细胞获得脂质的方法。 本发明还涉及通过本发明的方法制备的脂质。 本发明还涉及具有特定茴香胺值，过氧化值和/或磷含量的微生物脂质。
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