公开(公告)号：US20120214217A1

公开(公告)日：2012-08-23

申请号：US13402627

申请日：2012-02-22

Applicant: Shawn Patrick Grogan ,  Darryl David D'Lima ,  Clifford W. Colwell, JR. ,  Sungho Jin

Inventor： Shawn Patrick Grogan ,  Darryl David D'Lima ,  Clifford W. Colwell, JR. ,  Sungho Jin

IPC: C12N13/00 ,  A61N2/10 ,  C12N5/07

CPC classification number: C12N5/0655 ,  A61K35/12 ,  C12N2529/00 ,  C12N2533/10 ,  C12N2533/74

Abstract: Methods are provided for the three dimensional manipulation of cells, and for the formation of an organized engineered cell tissue. Also provided are the organized engineered cell tissues produced by the methods. In one method, a plurality of magnetically labeled cells are mixed with a cross-linkable hydrogel to form a cell-hydrogel mixture, the at least a portion of the plurality of magnetically labeled cells are manipulated with a magnetic field to arrange the magnetically labeled cells into a specific cellular arrangement, and the hydrogel is crosslinked to form the organized engineered cell tissue. The approach presented herein offers a means to circumvent the deficiencies in the field of regenerative medicine, and allows for the production of organized tissues in situ with specific cellular organizations that mimic the native tissue.

Abstract translation: 提供了用于细胞的三维操作以及形成有组织的工程细胞组织的方法。 还提供了通过该方法生产的有组织的工程细胞组织。 在一种方法中，将多个磁性标记的细胞与可交联水凝胶混合以形成细胞 - 水凝胶混合物，用磁场操纵多个磁性标记的细胞的至少一部分，以将磁性标记细胞 进入特定的细胞布置，并且水凝胶被交联以形成有组织的工程细胞组织。 本文提出的方法提供了一种方法来规避再生医学领域的缺陷，并且允许用模拟天然组织的特定细胞组织原位生产有组织的组织。

公开(公告)号：US08020216B2

公开(公告)日：2011-09-13

申请号：US11914108

申请日：2006-05-10

Applicant: Sungho Jin

Inventor： Sungho Jin

IPC: G01Q70/16

CPC classification number: G01Q70/12 ,  Y10S977/875 ,  Y10S977/878

Abstract: Probe structures and fabrication techniques are described. The described probe structures can be used as probes for various applications such as conductance measurement probes, field emitter probes, nanofabrication probes, and magnetic bit writing or reading probes.

Abstract translation: 描述了探头结构和制造技术。 所描述的探针结构可用作各种应用的探针，例如电导测量探针，场致发射探针，纳米制造探针和磁头写入或读取探针。

公开(公告)号：US07868850B2

公开(公告)日：2011-01-11

申请号：US11223130

申请日：2005-09-12

Applicant: Sungho Jin ,  Dong-Wook Kim ,  In Kyung Yoo

Inventor： Sungho Jin ,  Dong-Wook Kim ,  In Kyung Yoo

IPC: G09G3/28 ,  G09G5/00 ,  G06F3/02

CPC classification number: H01J1/46 ,  G09G3/22 ,  H01J29/467 ,  H01J31/127

Abstract: Field emitter arrays with split gates and methods for operating the same. A field emitter array may include one or more pairs of split gates, each connected to a corresponding voltage source, the split gates forming at least one gate hole for at least one emitter tip. Voltages, for example, AC voltages V1 and V2 may be applied to the split gates to perform one- or two-dimensional scanning or tilting depending on a ratio of V1 and V2.

Abstract translation: 具有分裂门的场发射极阵列及其操作方法。 场发射器阵列可以包括一对或多对分离栅极，每对分离栅极连接到相应的电压源，分离栅极形成用于至少一个发射极尖端的至少一个栅极孔。 电压，例如，交流电压V1和V2可以施加到分离门，以根据V1和V2的比率执行一维或二维扫描或倾斜。

公开(公告)号：US07465210B2

公开(公告)日：2008-12-16

申请号：US11060153

申请日：2005-02-17

Applicant: Dong-Wook Kim ,  Sungho Jin ,  In-Kyung Yoo ,  Li-Han Chen

Inventor： Dong-Wook Kim ,  Sungho Jin ,  In-Kyung Yoo ,  Li-Han Chen

IPC: H01J9/00 ,  H01J9/39 ,  H01J9/04

CPC classification number: H01J31/127 ,  H01J9/025 ,  H01J29/04 ,  H01J2201/3043 ,  H01J2201/30434 ,  H01J2201/30465 ,  H01J2201/30469 ,  H01J2201/30484 ,  H01J2201/30488

Abstract: This invention discloses novel field emitters which exhibit improved emission characteristics combined with improved emitter stability, in particular, new types of carbide or nitride based electron field emitters with desirable nanoscale, aligned and sharped-tip emitter structures.

Abstract translation: 本发明公开了具有改进的发射特性与改进的发射极稳定性相结合的新型场致发射体，特别是新型的具有理想的纳米尺度，排列和尖尖发射极结构的碳化物或氮化物基电子场发射体。

公开(公告)号：US20070238184A1

公开(公告)日：2007-10-11

申请号：US11450146

申请日：2006-06-09

Applicant: Ratnesh Lal ,  Arjan Quist ,  Sungho Jin ,  Hai Lin

Inventor： Ratnesh Lal ,  Arjan Quist ,  Sungho Jin ,  Hai Lin

IPC: G01N33/00 ,  B01J47/00 ,  C01B31/00

CPC classification number: C07K14/4711 ,  B01J20/205 ,  C01B32/18 ,  G01N33/6872 ,  G01N33/6896 ,  G01N2333/4709 ,  G01N2500/00 ,  G01N2800/2821 ,  G01Q60/38 ,  G01Q70/12

Abstract: The present invention relates to a novel channel structure of human amyloid beta protein (AbP) in lipid membranes and a rapid, quantitative and specific assay for screening test compounds, such as drugs, ligands (natural or synthetic), proteins, peptides and small organic molecules for their ability to bind and block the membrane AbP channels. The invention further relates to screening and identifying therapeutically relevant compounds for treating Alzheimer's disease and other disorders.

Abstract translation: 本发明涉及脂质膜中人淀粉样蛋白β蛋白（AbP）的新型通道结构，以及用于筛选测试化合物如药物，配体（天然或合成），蛋白质，肽和小有机物的快速，定量和特异性测定 分子能够结合和阻断膜的AbP通道。 本发明还涉及筛选和鉴定用于治疗阿尔茨海默氏病和其他疾病的治疗相关化合物。

公开(公告)号：US07268475B1

公开(公告)日：2007-09-11

申请号：US08771369

申请日：1996-12-16

Applicant: Sungho Jin ,  Gregory Peter Kochanski ,  Wei Zhu

Inventor： Sungho Jin ,  Gregory Peter Kochanski ,  Wei Zhu

IPC: H01J1/88

CPC classification number: H01J9/242 ,  H01J29/864 ,  H01J31/123 ,  H01J2329/863 ,  H01J2329/8635 ,  H01J2329/864 ,  H01J2329/8645

Abstract: In accordance with the invention, a field emission device is made by providing the device electrodes, forming a plurality of corrugated insulating rods with discontinuous coatings of conductive or semiconductive material with low secondary electron emission coefficient, adhering the rods to an electrode, cutting the rods to define corrugated pillars, and finishing the device. The result is low cost production of a field emission device having superior resistance to breakdown in high field operation.

Abstract translation: 根据本发明，通过提供器件电极，形成具有低二次电子发射系数的导电或半导体材料的不连续涂层的多个波纹绝缘棒，将棒粘附到电极上，切割棒 定义波纹柱，并整理设备。 结果是在高场操作中具有优异的耐击穿性的场致发射装置的低成本生产。

公开(公告)号：US20060054879A1

公开(公告)日：2006-03-16

申请号：US11014534

申请日：2004-12-16

Applicant: Sungho Jin

Inventor： Sungho Jin

IPC: H01L29/06 ,  H01L21/00

CPC classification number: B82Y10/00 ,  H01J1/304 ,  H01J3/022 ,  H01J9/025 ,  H01J2201/30469 ,  H01J2237/0635 ,  H01J2329/00 ,  Y10S977/939

Abstract: This invention provides novel methods of fabricating novel gated field emission structures that include aligned nanowire electron emitters (individually or in small groups) localized in central regions within gate apertures. It also provides novel devices using nanoscale emitters for microwave amplifiers, electron-beam lithography, field emission displays and x-ray sources. The new emission structures are particularly useful in the new devices

Abstract translation: 本发明提供了制造新型门控场发射结构的新方法，其包括定位在门孔内的中心区域中的排列的纳米线电子发射体（单独地或小组）。 它还提供了使用微波放大器，电子束光刻，场发射显示器和x射线源的纳米尺度发射器的新型器件。 新的发射结构在新器件中特别有用

公开(公告)号：US07012266B2

公开(公告)日：2006-03-14

申请号：US10350642

申请日：2003-01-24

Applicant: Sungho Jin

Inventor： Sungho Jin

IPC: H01J37/065

CPC classification number: B82Y10/00 ,  B82Y40/00 ,  H01J37/3177 ,  H01J2201/30 ,  H01J2237/0635 ,  Y10S977/901

Abstract: In accordance with the present invention, apparatus for performing electron beam lithography on selected portions of a substrate having a resist covered surface comprises a plurality of nanoscale electron emitters for emitting directional beams of electrons and, for each emitter, a directional control element to direct the emitted beam toward the selected portions. In a preferred embodiment the emitters comprise carbon nanotubes, and the directional control elements comprise micro-electro-mechanical disks in a two-dimensional array. In an alternative embodiment the directional control elements are electrodes.

Abstract translation: 根据本发明，用于在具有抗蚀剂覆盖表面的衬底的选定部分上进行电子束光刻的装置包括用于发射电子的定向束的多个纳米级电子发射器，并且对于每个发射器，定向控制元件引导 向所选择的部分发射光束。 在优选实施例中，发射器包括碳纳米管，并且方向控制元件包括二维阵列中的微机电盘。 在替代实施例中，方向控制元件是电极。

公开(公告)号：US06987027B2

公开(公告)日：2006-01-17

申请号：US10646502

申请日：2003-08-23

Applicant: Sungho Jin

Inventor： Sungho Jin

IPC: H01L21/00

CPC classification number: H01J3/021 ,  H01J9/025 ,  H01J21/10 ,  Y10S977/939

Abstract: The invention comprises a method of fabricating a vacuum microtube device comprising the steps of forming a cathode layer comprising an array of electron emitters, forming a gate layer comprising an array of openings for passing electrons from the electron emitters, and forming an anode layer for receiving electrons from the emitters. The cathode gate layer and the anode layer are vertically aligned and bonded together with intervening spacers on a silicon substrate so that electrons from respective emitters pass through respective gate openings to the anode. The use of substrate area is highly efficient and electrode spacing can be precisely controlled. An optional electron multiplying structure providing secondary electron emission material can be disposed between the gate layer and the anode in the path of emitted electrons.

Abstract translation: 本发明包括一种制造真空微管装置的方法，包括以下步骤：形成包括电子发射体阵列的阴极层，形成包含用于使来自电子发射体的电子的开口阵列的栅极层，以及形成用于接收的阳极层 来自发射体的电子。 阴极栅极层和阳极层与硅衬底上的中间间隔物垂直对准并结合在一起，使得来自各个发射体的电子通过相应的栅极开口到达阳极。 衬底面积的使用是高效的，电极间距可以精确控制。 提供二次电子发射材料的可选的电子倍增结构可以在发射电子的路径中设置在栅极层和阳极之间。

公开(公告)号：US06915046B2

公开(公告)日：2005-07-05

申请号：US10054499

申请日：2002-01-22

Applicant: Sungho Jin ,  Hareesh Mavoori ,  Roland Ryf

Inventor： Sungho Jin ,  Hareesh Mavoori ,  Roland Ryf

IPC: G02B6/35 ,  G02B26/08 ,  G02B6/26

CPC classification number: G02B6/3518 ,  G02B6/352 ,  G02B6/3546 ,  G02B6/3556 ,  G02B6/357 ,  G02B26/0841

Abstract: A MEMs mirror device comprises a mirror layer, a frame structure, and an actuator layer. At least one mirror is movably coupled to the frame. The actuator layer includes at least one conductive path for moving the mirror. In accordance with the invention, the mirror is curved for efficiently directing and focusing reflected light. The mirror comprises a metal-coated base, and curvature can be achieved by doping selected regions of the base or by using coating/base combinations with sufficient mismatch that they be curved by differential thermal expansion. The resulting MEMs devices are advantageous for optical switching, variable attenuation and power gain equalization.

Abstract translation: MEM镜装置包括镜层，框架结构和致动器层。 至少一个反射镜可移动地联接到框架。 致动器层包括用于移动反射镜的至少一个导电路径。 根据本发明，镜子是弯曲的，以有效地引导和聚焦反射光。 反射镜包括金属涂覆的基底，并且可以通过掺杂基底的选定区域或通过使用具有足够的不匹配的涂层/基底组合来实现曲率，使得它们通过差分热膨胀而弯曲。 所得到的MEMs器件对于光开关，可变衰减和功率增益均衡是有利的。