FLUID CONTROLLING APPARATUS AND METHOD OF CONTROLLING FLUID BY USING THE SAME
    41.
    发明申请
    FLUID CONTROLLING APPARATUS AND METHOD OF CONTROLLING FLUID BY USING THE SAME 有权
    流体控制装置及其使用方法控制流体

    公开(公告)号:US20130086998A1

    公开(公告)日:2013-04-11

    申请号:US13571202

    申请日:2012-08-09

    IPC分类号: G01N1/20

    摘要: A fluid controlling apparatus including at least one sample chamber for holding a fluid containing target materials; a cleaning chamber for holding a cleaning solution; a first multi-port connected to the at least one sample chamber through a first channel and connected to the cleaning chamber through a second channel; a filter portion, connected to the first multi-port through a third channel, for filtering the target materials; and a first pump, connected to the filter portion, for applying a pressure; and a method of controlling a fluid using the fluid controlling apparatus, which comprises passing the fluid containing the target materials from the at least one sample chamber to the filter portion; and cleaning a path of the fluid by passing the cleaning solution through the path.

    摘要翻译: 一种流体控制装置,包括用于保持含有目标材料的流体的至少一个样品室; 用于保持清洁溶液的清洁室; 第一多端口,其通过第一通道连接到所述至少一个样品室,并通过第二通道连接到所述清洁室; 过滤器部分,通过第三通道连接到第一多端口,用于过滤目标材料; 以及连接到过滤器部分的用于施加压力的第一泵; 以及使用所述流体控制装置控制流体的方法,所述方法包括将包含所述目标材料的流体从所述至少一个样品室传送到所述过滤器部分; 以及通过使清洁溶液通过路径来清洁流体的路径。

    Device for controlling particle distribution in an evaporating droplet using radial electroosmotic flow
    44.
    发明授权
    Device for controlling particle distribution in an evaporating droplet using radial electroosmotic flow 有权
    用于使用径向电渗流控制蒸发液滴中的颗粒分布的装置

    公开(公告)号:US08287707B2

    公开(公告)日:2012-10-16

    申请号:US11501124

    申请日:2006-08-08

    IPC分类号: B01D57/00 B01D15/00

    CPC分类号: C07K1/26

    摘要: Provided is a device for controlling a particle distribution in a droplet including particles. The device includes: a first electrode for developing an electric field in the vicinity of the droplet; and a second electrode for developing the electric field that is fixed to a substrate, is insulated from the first electrode, and located at about the center of the droplet. A micro electrode system including a circular electrode placed along a droplet rim and a point electrode at about the center of the bottom is used to cause radial electroosmotic flow, thereby obtaining a uniform solute distribution after complete evaporation of the droplet. The direction and strength of the radial electroosmotic flow can be varied and the radial electroosmotic flow is periodically applied. Particles used to obtain uniformity are selected from the group consisting of a polymer, an organic substance, an inorganic substance, a metal, and a biomolecule. The particles can be neutral, negatively charged or positively charged.

    摘要翻译: 提供了一种用于控制包含颗粒的液滴中的颗粒分布的装置。 该装置包括:用于在液滴附近形成电场的第一电极; 并且用于显影固定到基板的电场的第二电极与第一电极绝缘,并且位于液滴的中心附近。 使用包括沿着液滴边缘放置的圆形电极和位于底部中心附近的点电极的微电极系统引起径向电渗流,从而在液滴完全蒸发之后获得均匀的溶质分布。 径向电渗流的方向和强度可以变化,并且周期性地施加径向电渗流。 用于获得均匀性的颗粒选自聚合物,有机物质,无机物质,金属和生物分子。 颗粒可以是中性的,带负电的或带正电的。

    TARGET PARTICLES-SEPARATING DEVICE AND METHOD USING MULTI-ORIFICE FLOW FRACTIONATION CHANNEL
    47.
    发明申请
    TARGET PARTICLES-SEPARATING DEVICE AND METHOD USING MULTI-ORIFICE FLOW FRACTIONATION CHANNEL 有权
    目标颗粒分离装置和使用多元流动分离通道的方法

    公开(公告)号:US20110303586A1

    公开(公告)日:2011-12-15

    申请号:US13156630

    申请日:2011-06-09

    IPC分类号: B03B7/00 B07B1/00

    摘要: A device separating target particles in a fluid sample includes first through third multi-orifice flow fractionation (“MOFF”) channels, each including a multi-orifice segment with an inlet and an outlet at opposite ends, and an alternating series of contraction channels and expansion chambers interconnected in a lengthwise direction; a first separation unit including a first separation channel which is interconnected in fluid communication with a center region of the outlet of the first MOFF channel, and first branch channels which are interconnected in fluid communication with sidewall regions of the outlet of the first MOFF channel, and respectively with inlets of the second and third MOFF channels; and buffer inlets which are connected to the inlets of the second and third MOFF channels and through which a buffer flows into the second and third MOFF channels.

    摘要翻译: 分离流体样品中的目标颗粒的装置包括第一至第三多孔流动分馏(“MOFF”)通道,每个通道包括具有相对端的入口和出口的多孔段,以及交替的一系列收缩通道和 膨胀室沿长度方向互相连接; 第一分离单元,包括与第一MOFF通道的出口的中心区域流体连通的第一分离通道和与第一MOFF通道的出口的侧壁区域流体连通地互连的第一分支通道, 并分别具有第二和第三MOFF通道的入口; 以及连接到第二和第三MOFF通道的入口并且缓冲器通过其流入第二和第三MOFF通道的缓冲器入口。

    MICROFLUIDIC DEVICE USING MICROFLUIDIC CHIP AND MICROFLUIDIC DEVICE USING BIOMOLECULE MICROARRAY CHIP
    48.
    发明申请
    MICROFLUIDIC DEVICE USING MICROFLUIDIC CHIP AND MICROFLUIDIC DEVICE USING BIOMOLECULE MICROARRAY CHIP 有权
    使用生物分子微量芯片的微流控芯片和微流化器件的微流体装置

    公开(公告)号:US20110257037A1

    公开(公告)日:2011-10-20

    申请号:US13168298

    申请日:2011-06-24

    摘要: Disclosed is a microfluidic device including a microfluidic structure formed in a platform in which various examinations, such as an immune serum examination, can be automatically performed using the biomolecule microarray chip. The biomolecule microarray chip-type microfluidic device using a biomolecule microarray chip comprises: a platform which is rotatable; a microfluidic structure disposed in the platform, comprising: a plurality of chambers; a plurality of channels connecting the chambers each other; and a plurality of valves controlling flow of fluids through the channels, wherein the microfluidic structure controls flow of a fluid sample using rotation of the platform and the valves; and a biomolecule microarray chip mounted in the platform such that biomolecule capture probes bound to the biomolecule microarray chip contact the fluid sample in the microfluidic structure.

    摘要翻译: 公开了一种微流体装置,其包括在平台中形成的微流体结构,其中可以使用生物分子微阵列芯片自动执行各种检查,例如免疫血清检查。 使用生物分子微阵列芯片的生物分子微阵列芯片型微流器件包括:可旋转的平台; 设置在平台中的微流体结构,包括:多个室; 连接所述室的多个通道; 以及多个阀,其控制通过所述通道的流体流动,其中所述微流体结构通过所述平台和所述阀的旋转来控制流体样品的流动; 以及安装在平台中的生物分子微阵列芯片,使得与生物分子微阵列芯片结合的生物分子捕获探针与微流体结构中的流体样品接触。