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    Composition for forming release layer, and release layer
    31.
    发明授权
    Composition for forming release layer, and release layer 有权

    公开(公告)号：US11130855B2

    公开(公告)日：2021-09-28

    申请号：US16633868

    申请日：2018-07-26

    Applicant: NISSAN CHEMICAL CORPORATION

    Inventor： Kazuya Shindo ,  Tokio Nishita ,  Kazuya Ebara ,  BangChing Ho

    IPC: C08L33/14 ,  C08L45/00 ,  C08G71/02 ,  C08L27/12 ,  C08L79/04 ,  C09D133/14 ,  B32B27/00 ,  C08K5/16 ,  C08K5/42

    Abstract: Provided is a composition for forming release layers which comprises (A) a polyurea including a repeating unit represented by formula (1), (B) an acid compound or a salt thereof, (C) a crosslinking agent selected from among compounds having a nitrogen atom substituted by a hydroxyalkyl group and/or an alkoxymethyl group, (D) a polymeric additive including a repeating unit represented by formula (a1), a repeating unit represented by formula (b), and a repeating unit represented by formula (c), and (E) a solvent, wherein the polymeric additive (D) is contained in an amount of 5-100 parts by mass per 100 parts by mass of the polyurea (A). (In the formulae, the RA moieties each are independently a hydrogen atom or a methyl group; RB1 is a branched C3-4 alkyl group in which at least one hydrogen atom has been replaced with a fluorine atom; RC is a C1-10 hydroxyalkyl group; and RD is a C6-20 polycycloalkyl group or C6-12 aryl group.)

    METHODS FOR FORMING HIGH SHRINK WRAP LABEL SLEEVES
    38.
    发明申请
    METHODS FOR FORMING HIGH SHRINK WRAP LABEL SLEEVES 有权

    公开(公告)号：US20210139689A1

    公开(公告)日：2021-05-13

    申请号：US17157140

    申请日：2021-01-25

    Applicant: Polysack Flexible Packaging Ltd.

    Inventor： Izhar Halahmi ,  Nitai Alush-aben

    IPC: C08L33/14 ,  C08L35/02 ,  B65C9/00 ,  B65C9/26 ,  B65C3/06

    Abstract: Methods for forming high shrink wrap label sleeves directly from a roll are disclosed herein. A seaming agent is applied to the label, where the trailing edge will overlap the leading edge to form a seam. The seaming agent is then exposed to radiation to cure the seaming agent and form a sleeve. The label comprises a film with at least one external layer that has a Hildebrand solubility parameter, and the seaming agent includes a component having a Hildebrand solubility parameter that is within 2.2 MPa1/2 or within 4.4 calories1/2·cm−3/2 of the Hildebrand solubility parameter of the external layer of the film. The seaming agent also has a viscosity of at least 1 centipoise and less than 1000 centipoise when measured at any temperature between ambient temperature and 60° C.

    RESIDENCE STRUCTURES AND RELATED METHODS
    39.
    发明申请
    RESIDENCE STRUCTURES AND RELATED METHODS 有权

    公开(公告)号：US20210113460A1

    公开(公告)日：2021-04-22

    申请号：US17126786

    申请日：2020-12-18

    Applicant: Massachusetts Institute of Technology ,  The Brigham and Women's Hospital, Inc.

    Inventor： Andrew Bellinger ,  Shiyi Zhang ,  Carlo Giovanni Traverso ,  Robert S. Langer ,  Stacy Mo ,  Tyler Grant ,  Mousa Jafari ,  Dean Liang Glettig ,  Angela DiCiccio ,  Lowell L. Wood, JR. ,  Philip A. Eckhoff

    IPC: A61K9/00 ,  A61K31/65 ,  A61K9/48 ,  A61M31/00 ,  A61K47/58 ,  A61K47/40 ,  A61K47/32 ,  C08G18/73 ,  C08G18/42 ,  A61K31/7048 ,  C08L33/14 ,  A61K47/34 ,  A61K31/357 ,  A61K47/42 ,  A61K47/69 ,  C08G83/00 ,  C08L33/02 ,  C08L33/08 ,  C08G63/08 ,  A61K47/10

    Abstract: Residence structures, systems, and related methods are generally provided. Certain embodiments comprise administering (e.g., orally) a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. The residence structure may be, in some cases, a gastric residence structure. In some embodiments, the structures and systems described herein comprise one or more materials configured for high levels of active substances (e.g., a therapeutic agent) loading, high active substance and/or structure stability in acidic environments, mechanical flexibility and strength in an internal orifice (e.g., gastric cavity), easy passage through the GI tract until delivery to at a desired internal orifice (e.g., gastric cavity), and/or rapid dissolution/degradation in a physiological environment (e.g., intestinal environment) and/or in response to a chemical stimulant (e.g., ingestion of a solution that induces rapid dissolution/degradation). In certain embodiments, the structure has a modular design, combining a material configured for controlled release of therapeutic, diagnostic, and/or enhancement agents with a structural material necessary for gastric residence but configured for controlled and/or tunable degradation/dissolution to determine the time at which retention shape integrity is lost and the structure passes out of the gastric cavity. For example, in certain embodiments, the residence structure comprises a first elastic component, a second component configured to release an active substance (e.g., a therapeutic agent), and, optionally, a linker. In some such embodiments, the linker may be configured to degrade such that the residence structure breaks apart and is released from the location internally of the subject after a predetermined amount of time.

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