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    Irrigated catheter
    31.
    发明授权
    Irrigated catheter 有权
    灌注导管

    公开(公告)号：US08894642B2

    公开(公告)日：2014-11-25

    申请号：US11596722

    申请日：2005-05-17

    Applicant: Charles A. Gibson ,  Gary S. Falwell ,  Hab Seang

    Inventor： Charles A. Gibson ,  Gary S. Falwell ,  Hab Seang

    IPC: A61B18/18 ,  A61B18/14 ,  A61B18/00

    CPC classification number: A61B18/1492 ,  A61B2018/00029

    Abstract: Apparatus for irrigating an electrode of a catheter are disclosed. Among other things, a catheter is disclosed that comprises a shaft portion including a fluid passage to conduct fluid, an electrode coupled to a distal end of the shaft portion, and a handle portion coupled to a proximal end of the shaft portion. A portion of the fluid passage defines an opening in the shaft portion. The opening is constructed and arranged such that when fluid is conducted through the fluid passage, at least some of the fluid will contact the electrode after passing through the opening in the shaft portion.

    Abstract translation: 公开了一种用于冲洗导管电极的装置。 除其他之外，公开了一种导管，其包括轴部分，其包括用于传导流体的流体通道，耦合到所述轴部分的远端的电极以及联接到所述轴部分的近端的手柄部分。 流体通道的一部分在轴部分中限定开口。 开口被构造和布置成使得当流体通过流体通道传导时，至少一些流体在通过轴部分中的开口之后将接触电极。

    Ablation catheter
    34.
    发明授权
    Ablation catheter 失效
    消融导管

    公开(公告)号：US06974457B2

    公开(公告)日：2005-12-13

    申请号：US10250854

    申请日：2002-01-04

    Applicant: Charles A. Gibson

    Inventor： Charles A. Gibson

    IPC: A61N1/05 ,  A61B18/04 ,  A61B18/14 ,  A61B18/16

    CPC classification number: A61B18/14 ,  A61B2018/00083

    Abstract: An ablation catheter comprises a shaft and at least one ablation electrode which may be fixed or movable relative to the shaft. An insulating cap is placed over portions of the electrode which are susceptible to high current concentrations when RF energy is applied to the electrode. Typically, such portions occur in the region of abrupt surface transitions such as the edges of the electrode.

    Abstract translation: 消融导管包括轴和至少一个可相对于轴固定或移动的消融电极。 当RF电能施加到电极时，绝缘盖放置在电极的部分上，其易受高电流浓度的影响。 通常，这些部分出现在突然的表面转变区域，例如电极的边缘。

    Steerable catheter
    35.
    发明授权
    Steerable catheter 有权
    导向导管

    公开(公告)号：US06224587B1

    公开(公告)日：2001-05-01

    申请号：US09447440

    申请日：1999-11-22

    Applicant: Charles A. Gibson

    Inventor： Charles A. Gibson

    IPC: A61M2501

    CPC classification number: A61M25/0147 ,  A61B2018/00952 ,  A61M2025/0161

    Abstract: A medical device including an elongated shaft that is twisted through a predetermined angle. One or more lumen are formed in the shaft and twist through the predetermined angle as well. A pull wire extends through one of the lumen and attaches to a distal portion of the elongated shaft at an off-axis location. By tensioning the pull wire, the medical device can assume various complex curves, depending on the degree of twist imparted to the shaft.

    Abstract translation: 一种包括被扭转预定角度的细长轴的医疗装置。 一个或多个内腔形成在轴中并扭转预定角度。 拉线延伸穿过内腔中的一个并且在离轴位置附接到细长轴的远侧部分。 通过张紧拉线，医疗装置可以根据施加到轴的扭转程度来呈现各种复杂的曲线。

    Steerable electrode catheter
    36.
    发明授权
    Steerable electrode catheter 失效
    可导电电极导管

    公开(公告)号：US5935102A

    公开(公告)日：1999-08-10

    申请号：US736321

    申请日：1996-10-23

    Applicant: Russell W Bowden ,  Gary S. Falwell ,  Charles A. Gibson ,  Richard B. Stevens ,  Debbie E. Stevens-Wright

    Inventor： Russell W Bowden ,  Gary S. Falwell ,  Charles A. Gibson ,  Richard B. Stevens ,  Debbie E. Stevens-Wright

    IPC: A61B5/0402 ,  A61M25/01 ,  A61M25/092 ,  A61M37/00

    CPC classification number: A61M25/0144 ,  A61M25/0136 ,  A61M25/0147 ,  A61B18/1815 ,  A61B2017/003 ,  A61B2018/0016 ,  A61B2018/00916 ,  A61B2018/00946 ,  A61B2018/00952 ,  A61M25/0141

    Abstract: A steerable catheter includes control handle having a generally tubular housing with a longitudinal slot therein in which an axially or longitudinally movable two-part slideblock resides, and a generally cylindrical, rotatably mounted thumbwheel surrounding a distal portion of the tubular housing, for controlling the axial translation of the slideblock. The pullwire passes into the distal end of the control handle and is only secured to the proximal part of the two-part slideblock so as to prevent the user from placing the pullwire under compression. A tip radius adjusting wire is attached to and extends distally from a slide actuator in the control handle into and through the main catheter shaft portion. The free distal end of the tip radius adjusting wire is selectably locatable at different positions. The radius of curvature of the tip portion, when deflected, depends upon how far distally into the deflectable tip portion the radius adjusting wire has been advanced by the user. The electrode catheter thus has a deflectable tip whose radius of curvature is adjustable over a relatively wide range.

    Abstract translation: 可导向的导管包括控制手柄，其具有大致管状的壳体，其中纵向狭槽在其中，轴向或纵向可移动的两部分滑块位于其中，以及围绕管状壳体的远端部分的大致圆柱形可旋转地安装的指轮，用于控制轴向 幻灯片的翻译。 拉线进入控制手柄的远端，并且仅固定到两部分滑块的近端部分，以防止使用者将拉线放置在压缩状态。 尖端半径调节线附接到控制手柄中的滑块致动器并远离其延伸并且穿过主导管轴部分。 尖端半径调整线的自由端可选地位于不同位置。 尖端部分的弯曲半径在偏转时取决于使用者已经使半径调节线前进到可偏转尖端部分的远端。 因此，电极导管具有可偏转的尖端，其弯曲半径在相对宽的范围内是可调节的。

    Aminoethylethanolamine and ethylenediamine producers composition and method for producing same
    37.
    发明授权
    Aminoethylethanolamine and ethylenediamine producers composition and method for producing same 失效
    氨基乙基乙醇胺和乙二胺生产者组合物及其制备方法

    公开(公告)号：US4977266A

    公开(公告)日：1990-12-11

    申请号：US102928

    申请日：1987-09-30

    Applicant: Lloyd M. Burgess ,  Charles A. Gibson

    Inventor： Lloyd M. Burgess ,  Charles A. Gibson

    IPC: C07C209/16 ,  C07C213/02 ,  C07D295/023

    CPC classification number: C07D295/023 ,  C07C209/16 ,  C07C213/02

    Abstract: A continuously generated alkyleneamines producers composition comprising, based on 100% of the moles of the composition and exclusive of any MEA and water present,(a) about 15 to about 50 mole % AEEA,(b) about 15 to about 55 mole % EDA,(c) about 10 to about 20 mole % DETA,(d) about 5 to about 20 mole % of the combination of PIP, AEP and HEP,(e) about 3 to about 10 mole % of one or more of TETAs and TEPAs,(f) less than about 1 mole % of other polyalkylene polyamines,(g) an DETA to AEEA mole ratio less than 0.77, and(h) an EDA to AEEA mole ratio less than 8;and a process of manufacturing the same, which comprises feeding hydrogen, ammonia and MEA to a reaction zone containing a fixed bed of a reductive amination catalyst, wherein the hydrogen comprises about 20 to about 60 mole percent of the feed in the reaction zone and the mole ratio of ammonia to MEA is about 1 to about 5, the temperature of the reaction zone is about 120.degree. C. to about 300.degree. C., the pressure of the reaction zone is about 400 to about 1400 psig., the conversion of MEA is about 20 to about 45 weight percent, and recovering said producers composition from the reaction zone.

    Abstract translation: 连续生成的亚烷基胺生产商组合物，其包含基于组合物的摩尔数的100％，不包含任何MEA和水，（a）约15至约50摩尔％的AEEA，（b）约15至约55摩尔％的EDA ，（c）约10至约20摩尔％DETA，（d）PIP，AEP和HEP的组合约5至约20摩尔％，（e）约3至约10摩尔％的一种或多种TETA和 TEPA，（f）小于约1摩尔％的其它多亚烷基多胺，（g）DETA与AEEA摩尔比小于0.77，和（h）EDA与AEEA摩尔比小于8; 以及其制造方法，其包括将氢，氨和MEA进料到含有还原胺化催化剂固定床的反应区中，其中氢包含反应区中约20至约60摩尔％的进料和 氨与MEA的摩尔比为约1至约5，反应区的温度为约120℃至约300℃，反应区的压力为约400至约1400psig，转化率 MEA为约20至约45重量％，并从反应区回收所述生产者组合物。

    Process for preparing alkanolamines
    38.
    发明授权
    Process for preparing alkanolamines 失效
    烷醇胺的制备方法

    公开(公告)号：US4845296A

    公开(公告)日：1989-07-04

    申请号：US195395

    申请日：1988-05-12

    Applicant: Moinuddin Ahmed ,  James R. Nelson ,  Charles A. Gibson

    Inventor： Moinuddin Ahmed ,  James R. Nelson ,  Charles A. Gibson

    IPC: C07C213/04

    CPC classification number: C07C213/04

    Abstract: A process is provided for preparing alkanolamines having a high yield of monoalkanolamine which comprises reacting in a reaction mixture an alkylene oxide having from two to four carbon atoms with ammonia in a molar ratio of ammonia to alkylene oxide within the range from about 15.1 to about 50.1 at temperatures above the critical temperature of the reaction mixture and at pressures above the critical pressure of the reaction mixture and high enough to maintain the reaction mixture at sufficiently high fluid densities.

    Abstract translation: 提供了一种制备具有高产率的单烷醇胺的链烷醇胺的方法，其包括在反应混合物中使具有2至4个碳原子的环氧烷与氨与氧化烯的摩尔比在约15.1至约50.1的范围内反应 在高于反应混合物的临界温度的温度和高于反应混合物的临界压力的压力下，并且足够高以将反应混合物保持在足够高的流体密度。

    Method of preparing polyethylene polyamines having improved color
    39.
    发明授权
    Method of preparing polyethylene polyamines having improved color 失效
    制备具有改进颜色的聚乙烯多胺的方法

    公开(公告)号：US4570019A

    公开(公告)日：1986-02-11

    申请号：US577323

    申请日：1984-02-08

    Applicant: Charles A. Gibson ,  John W. Crandall

    Inventor： Charles A. Gibson ,  John W. Crandall

    IPC: C07C85/00 ,  C07C85/26

    Abstract: A process is provided which may be run continuously for producing polyethylene polyamines having improved color characteristics which comprises treating discolored polyethylene polyamines with polyethylene polyamine hydrochloride in the presence of water at elevated temperatures for the time necessary to reduce the color of said polyethylene polyamines and then flash evaporating the decolorized polyethylene polyamines from the treating mixture.

    Abstract translation: 提供可以连续运行以生产具有改进的颜色特性的聚乙烯多胺的方法，该方法包括在高温下在水存在下用聚乙烯多胺盐酸盐处理变色聚乙烯多胺，所需时间降低所述聚乙烯多胺的颜色，然后闪蒸 从处理混合物中蒸发脱色的聚乙烯多胺。

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