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    Method for Detecting Analytes
    34.
    发明申请
    Method for Detecting Analytes 有权
    检测分析物的方法

    公开(公告)号：US20110020833A1

    公开(公告)日：2011-01-27

    申请号：US12666024

    申请日：2008-06-20

    申请人： Andreas Bergmann ,  Joachim Struck

    发明人： Andreas Bergmann ,  Joachim Struck

    IPC分类号： G01N33/53 ,  G01N33/543 ,  G01N30/00 ,  G01N31/22

    CPC分类号： G01N33/54306

    摘要： The subject of this invention is a process for detection of analytes from biological samples comprising the following process steps: a) Preparation of a reversible binding partner 1 that is immobilized on a solid phase, to which an analyte binder is reversibly bonded via a reversible binding partner 2 that is bonded to the analyte binder, whereby the analyte binder is immobilized by binding between the reversible binding partners 1 and 2, b) Addition of the biological sample and binding of the analyte to the reversible immobilized analyte binder in the case that the biological sample contains the analytes, c) Separation of the biological sample, d) Addition of a dissolving buffer, which dissolves the binding between the reversible binding partners 1 and 2, whereby the binding of the analyte to the analyte binder remains optional, and e) Detection of the analyte in the dissolving buffer in the case that the biological sample contains the analytes and determination of the absence of the analyte in the case that the biological sample does not contain the analytes, respectively.

    摘要翻译： 本发明的主题是用于检测来自生物样品的分析物的方法，包括以下过程步骤：a）固定在固相上的可逆结合配偶体1的制备，分析物粘合剂通过可逆结合可逆地结合到其上 配偶体2，其结合到分析物粘合剂上，由此通过可逆结合配偶体1和2之间的结合固定分析物粘合剂，b）添加生物样品并将分析物与可逆固定的分析物结合物结合， 生物样品含有分析物，c）生物样品的分离，d）加入溶解缓冲液，其溶解可逆结合配偶体1和2之间的结合，由此分析物与分析物质粘合剂的结合仍然是可选的，e ）在生物样品含有分析物和确定不存在分析物的情况下，检测溶解缓冲液中的分析物 在生物样品不分别含有分析物的情况下分析物。

    DIAGNOSIS AND RISK STRATIFICATION OF CARDIAC INSUFFICIENCY USING NEUROPHYSIN
    37.
    发明申请
    DIAGNOSIS AND RISK STRATIFICATION OF CARDIAC INSUFFICIENCY USING NEUROPHYSIN 审中-公开
    使用神经元蛋白的心脏缺血病的诊断和风险分析

    公开(公告)号：US20100093012A1

    公开(公告)日：2010-04-15

    申请号：US12518180

    申请日：2007-12-10

    申请人： Andreas Bergmann ,  Joachim Struck

    发明人： Andreas Bergmann ,  Joachim Struck

    IPC分类号： C12Q1/28 ,  C12Q1/02 ,  C12Q1/25

    CPC分类号： G01N33/6893 ,  G01N2800/32 ,  G01N2800/324 ,  G01N2800/325

    摘要： The invention relates to a method for the diagnosis and/or risk stratification of cardiac insufficiency, according to which the marker neurophysin or a fragment or partial peptide thereof is determined on patients to be examined. The invention also relates to advantageous marker combinations containing neurophysin, and to a diagnostic device and a kit for carrying out the method.

    摘要翻译： 本发明涉及一种用于诊断和/或危险分类心脏功能不全的方法，根据该方法，对待检查的患者确定标记物神经生物素或其片段或部分肽。 本发明还涉及含有神经生物素的有利的标记组合，以及用于实施该方法的诊断装置和试剂盒。