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    Multi-mode communication ingestible event markers and systems, and methods of using the same
    21.
    发明授权
    Multi-mode communication ingestible event markers and systems, and methods of using the same 有权
    多模式通信可摄取事件标记和系统及其使用方法

    公开(公告)号：US09258035B2

    公开(公告)日：2016-02-09

    申请号：US14699809

    申请日：2015-04-29

    申请人： Proteus Digital Health, Inc.

    发明人： Timothy Robertson ,  Mark Zdeblick

    IPC分类号： H04Q5/22 ,  H04B5/00 ,  A61B5/00 ,  A61B5/07 ,  G06K7/10

    CPC分类号： H04B5/0062 ,  A61B5/0031 ,  A61B5/073 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/6861 ,  A61B2562/08 ,  A61B2562/162 ,  G06K7/10297

    摘要： A device including an integrated circuit, a partial power source, including first and second materials associated with the integrated circuit is disclosed. The first and second materials are configured to provide a voltage potential difference when in contact with a conductive fluid to power up the device. A signal amplification element secured around the integrated circuit relative to the first and second materials is configured to facilitate extension of a current flow path between the first and second materials. A modulator is configured to control conductance between the first and second materials to generate a detectable signal that is partially defined by the current flow extending through the conductive fluid. A communication module is coupled to the partial power source and is configured to communicate with a receiver and an antenna electrically coupled to the communication module, which uses the antenna to communicate with the receiver.

    摘要翻译： 公开了一种包括集成电路，部分电源的装置，包括与集成电路相关联的第一和第二材料。 第一和第二材料配置成当与导电流体接触时提供电压电位差，以使设备加电。 围绕集成电路相对于第一和第二材料固定的信号放大元件构造成有助于在第一和第二材料之间扩展电流流动路径。 调制器被配置为控制第一和第二材料之间的电导，以产生由延伸穿过导电流体的电流部分地限定的可检测信号。 通信模块耦合到部分电源，并且被配置为与接收器和电连接到通信模块的天线进行通信，所述通信模块使用天线与接收机进行通信。

    OPACITY CONSISTENT POLYMER GRAFT FOR OPTICAL SENSOR
    29.
    发明申请
    OPACITY CONSISTENT POLYMER GRAFT FOR OPTICAL SENSOR 有权
    光学传感器的一致性聚合物光栅

    公开(公告)号：US20140343381A1

    公开(公告)日：2014-11-20

    申请号：US14279759

    申请日：2014-05-16

    申请人： Senseonics, Incorporated

    发明人： Todd Whitehurst ,  Philip Huffstetler

    IPC分类号： A61B5/1455 ,  A61B5/145

    CPC分类号： A61B5/1455 ,  A61B5/0031 ,  A61B5/14532 ,  A61B5/14552 ,  A61B5/1459 ,  A61B2562/162

    摘要： A sensor (e.g., an optical sensor) that may be placed within a living animal (e.g., a human) and may be used to measure an analyte (e.g., glucose or oxygen) in a medium (e.g., interstitial fluid) within the animal. The sensor may include a sensor housing and a polymer graft including indicator molecules and covering at least a portion of the sensor housing. The opacity of the polymer graft may remain substantially the same (i.e., may have little or no variation) over time. The sensor may include a photodetector, and variation in the opacity of the polymer graft does not cause a significant change in a measurement signal output by the photodetector. The polymer hydrogel may be made of polymers including acrylic acid and/or polyethylene glycol.

    摘要翻译： 可以放置在活的动物（例如人）内的传感器（例如，光学传感器），并且可以用于测量动物中的介质（例如，间质液）中的分析物（例如，葡萄糖或氧） 。 传感器可以包括传感器外壳和包括指示剂分子并且覆盖传感器外壳的至少一部分的聚合物移植物。 随着时间的推移，聚合物移植物的不透明度可以保持基本上相同（即，可能具有很小或没有变化）。 传感器可以包括光电检测器，并且聚合物移植物的不透明度的变化不会导致由光电检测器输出的测量信号的显着变化。 聚合物水凝胶可以由包括丙烯酸和/或聚乙二醇的聚合物制成。

    DEVICE AND SYSTEM FOR SENSING WITHIN IN-VIVO FLUIDS
    30.
    发明申请
    DEVICE AND SYSTEM FOR SENSING WITHIN IN-VIVO FLUIDS 审中-公开
    用于在流体流中感测的装置和系统

    公开(公告)号：US20140275860A1

    公开(公告)日：2014-09-18

    申请号：US14212304

    申请日：2014-03-14

    申请人： Given Imaging Ltd.

    发明人： Dan ROTTENBERG ,  Robert Sayegh

    IPC分类号： A61B5/02 ,  A61B1/06 ,  A61B1/04 ,  A61B5/00 ,  A61B5/07

    CPC分类号： A61B5/02042 ,  A61B1/00087 ,  A61B1/041 ,  A61B1/06 ,  A61B5/0084 ,  A61B5/073 ,  A61B5/4233 ,  A61B5/4238 ,  A61B5/4255 ,  A61B2562/162 ,  A61B2562/18

    摘要： Devices and a system for detection of blood within in-vivo fluids are provided. A device comprises a housing that includes a gap. The gap has at least one opening through which in-vivo fluids may enter and/or exit the gap. The device further comprises an illumination source for illuminating the in-vivo fluids in the gap, a light detector for detecting light which passes through the in-vivo fluids in the gap, and flexible fins disposed on the housing in the vicinity of the gap's opening for covering the opening when the fins are folded and for pumping fluids into and out of the opening by repeated closure and opening of the opening by the fins, due to repeated peristaltic waves. This pumping effect may lead to continuous flow of fluids into and out of the opening and thus into and out of the gap of the device.

    摘要翻译： 提供了用于检测体内流体内的血液的装置和系统。 一种装置包括包括间隙的壳体。 间隙具有至少一个开口，体内流体可通过该开口进入和/或离开间隙。 该装置还包括用于照射间隙中的体内流体的照明源，用于检测通过间隙中的体内流体的光的光检测器，以及设置在间隙开口附近的壳体上的柔性翅片 用于当翅片被折叠时覆盖开口，并且由于重复的蠕动波，通过由翅片重复地关闭和打开开口来将流体泵入和流出开口。 这种泵送效应可能导致流体连续流入和流出开口，从而进入和流出装置的间隙。