公开(公告)号：US06495104B1

公开(公告)日：2002-12-17

申请号：US09377681

申请日：1999-08-19

Applicant: Garrett Unno ,  Colin B. Kennedy ,  Patrick Kaltenbach ,  Manfred Berndt

Inventor： Garrett Unno ,  Colin B. Kennedy ,  Patrick Kaltenbach ,  Manfred Berndt

IPC: G01N1506

CPC classification number: B01L3/5027 ,  B01L3/502715 ,  B01L3/545 ,  B01L9/527 ,  B01L2200/025 ,  B01L2200/027 ,  B01L2200/143 ,  B01L2300/021 ,  B01L2300/0816 ,  B01L2400/0415 ,  B01L2400/0487 ,  G01N2035/00237

Abstract: Microfluidic devices and systems that include keying, registration or indication elements that communicate a functionality of the microfluidic device to the instrumentation which is used in conjunction with these devices. Indicator elements include structural indicators, electrical indicators, optical indicators and chemical indicators. Different indicator elements are indicative of different functionalities, e.g., applications, new vs. used, and the like.

Abstract translation: 微流体装置和系统包括将微流体装置的功能传递到与这些装置结合使用的仪器的键控，配准或指示元件。 指标要素包括结构指标，电气指标，光学指标和化学指标。 不同的指标元素指示不同的功能，例如应用，新的和使用的等等。

公开(公告)号：US06353475B1

公开(公告)日：2002-03-05

申请号：US09377891

申请日：1999-08-19

Applicant: Morten J. Jensen ,  Patrick Kaltenbach ,  Volker Brombacher

Inventor： Morten J. Jensen ,  Patrick Kaltenbach ,  Volker Brombacher

IPC: G01N2101

CPC classification number: G01N27/44721

Abstract: Systems and methods for analyzing a sample are disclosed. The system may include a light source operable to transmit light onto the sample, a detector operable to detect intensity of the light emitted from the sample, and a power modulator. The power modulator modulates the light source power such that light is emitted from the light source in more than one mode to reduce changes in the emitted light due to temperature changes in the light source.

公开(公告)号：USRE36350E

公开(公告)日：1999-10-26

申请号：US127556

申请日：1998-07-30

Applicant: Sally A. Swedberg ,  Patrick Kaltenbach ,  Klaus E. Witt ,  Fritz Bek ,  Laurie S. Mittelstadt

Inventor： Sally A. Swedberg ,  Patrick Kaltenbach ,  Klaus E. Witt ,  Fritz Bek ,  Laurie S. Mittelstadt

IPC: B01L3/00 ,  B01L3/02 ,  B01L7/00 ,  B29C65/02 ,  B81B1/00 ,  B81C1/00 ,  G01N27/447 ,  G01N30/02 ,  G01N30/28 ,  G01N30/30 ,  G01N30/60 ,  B01D15/08

CPC classification number: G01N30/6095 ,  B01L3/502707 ,  B01L7/54 ,  G01N27/44708 ,  G01N27/44773 ,  G01N27/44791 ,  B01L2200/025 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2200/10 ,  B01L2200/12 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2300/1822 ,  B01L2400/0415 ,  B01L2400/0421 ,  B01L2400/0442 ,  B01L2400/0487 ,  B01L3/0268 ,  B01L3/502715 ,  B01L3/5055 ,  B29C65/02 ,  B29C66/54 ,  B29C66/549 ,  G01N2030/285 ,  G01N2030/3007 ,  G01N2030/3015 ,  G01N2030/303 ,  G01N27/44721 ,  G01N30/02 ,  G01N30/60 ,  G01N30/6047 ,  G01N30/6052 ,  G01N30/606

Abstract: A miniaturized total analysis system (".mu.-TAS") comprising a miniaturized planar column device is described for use in liquid phase analysis. The .mu.-TAS comprises microstructures fabricated by laser ablation in a variety of novel support substrates. The .mu.-TAS includes associated laser-ablated features required for integrated sample analysis, such as analyte detection means and fluid communication means. .mu.-TAS constructed according to the invention is useful in any analysis system for detecting and analyzing small and/or macromolecular solutes in the liquid phase and may employ chromatographic separation means, electrophoretic separation means, electrochromatographic separation means, or combinations thereof.

Abstract translation: 描述了包括小型化平面柱装置的小型化总分析系统（“mu-TAS”）用于液相分析。 mu-TAS包括通过在各种新型支撑衬底中的激光烧蚀制造的微观结构。 mu -TAS包括用于集成样品分析所需的相关激光烧蚀特征，例如分析物检测装置和流体连通装置。 根据本发明构建的mu-TAS可用于检测和分析液相中的小分子和/或大分子溶质的任何分析系统，并且可以使用色谱分离装置，电泳分离装置，电色谱分离装置或其组合。

公开(公告)号：US5917606A

公开(公告)日：1999-06-29

申请号：US709017

申请日：1996-09-06

Applicant: Patrick Kaltenbach

Inventor： Patrick Kaltenbach

IPC: G01N21/05 ,  G01N27/447 ,  G01N30/74 ,  G01N21/00 ,  G01N1/10

CPC classification number: G01N21/05 ,  G01N27/44721 ,  G01N30/74 ,  G01N2021/0346 ,  G01N2030/746 ,  G01N2201/0642

Abstract: A photometric apparatus (100) for small sample volumes comprises a cell body (102), a light input means (104) arranged adjacent to a first surface of the cell body (102), a light source (105) emitting light of predetermined wavelength or wavelength range through the light input means (104), a light output means (106) arranged adjacent to a second surface of the cell body (102) opposite to the first surface, a light detector (107) arranged adjacent to the light out put means (104), and a flow channel (108) formed in the cell body (102), wherein surfaces of the walls of the channel (108) have a roughness smaller than the predetermined wavelength.

Abstract translation: 用于小样品体积的测光装置（100）包括电池体（102），与电池体（102）的第一表面相邻布置的光输入装置（104），发射预定波长的光的光源（105） 或波长范围，与第一表面相对的与电池体（102）的第二表面相邻布置的光输出装置（106），与光出射相邻布置的光检测器（107） 放置装置（104）和形成在电池体（102）中的流动通道（108），其中通道（108）的壁的表面具有小于预定波长的粗糙度。

公开(公告)号：US5641400A

公开(公告)日：1997-06-24

申请号：US546629

申请日：1995-10-23

Applicant: Patrick Kaltenbach ,  Sally A. Swedberg ,  Klaus E. Witt ,  Fritz Bek ,  Laurie S. Mittelstadt

Inventor： Patrick Kaltenbach ,  Sally A. Swedberg ,  Klaus E. Witt ,  Fritz Bek ,  Laurie S. Mittelstadt

IPC: B01L3/00 ,  B01L7/00 ,  B29C65/02 ,  B81B1/00 ,  B81C1/00 ,  G01N27/447 ,  G01N30/02 ,  G01N30/28 ,  G01N30/30 ,  G01N30/60 ,  B01D15/08

CPC classification number: B01L7/54 ,  B01L3/5027 ,  B01L3/502707 ,  B01L7/525 ,  G01N27/44708 ,  G01N27/44773 ,  G01N27/44791 ,  G01N30/6095 ,  B01L2200/025 ,  B01L2200/0689 ,  B01L2200/10 ,  B01L2200/12 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2300/0883 ,  B01L2300/0887 ,  B01L2300/12 ,  B01L2300/1822 ,  B01L2400/0415 ,  B01L2400/0421 ,  B01L3/502715 ,  B01L3/5055 ,  B29C65/02 ,  B29C66/54 ,  B29C66/549 ,  G01N2030/285 ,  G01N2030/3007 ,  G01N2030/3015 ,  G01N2030/303 ,  G01N27/44721 ,  G01N30/02 ,  G01N30/60 ,  G01N30/6047 ,  G01N30/6052 ,  G01N30/606

Abstract: Miniaturized planar column devices and miniaturized total analysis systems for liquid phase analysis are disclosed. The systems include a temperature control device for regulating temperature, preferably a thermoelectric device comprising Peltier elements.

Abstract translation: 公开了用于液相分析的小型化平面柱装置和小型化总分析系统。 该系统包括用于调节温度的温度控制装置，优选包括珀尔帖元件的热电装置。