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公开(公告)号：US06881809B2
公开(公告)日：2005-04-19
申请号：US10848308
申请日：2004-05-18
CPC分类号： C07F7/081 , Y10S623/905 , Y10S623/907
摘要： Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based silyl monomers or the copolymerization of one or more aromatic-based silyl monomers with one or more aromatic or non-aromatic non-siloxy-based monomers, hydrophobic monomers or hydrophilic monomers.
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22.发明授权公开(公告)号：US06790318B2
公开(公告)日：2004-09-14
申请号：US10260449
申请日：2002-09-27
IPC分类号： B01D1100
CPC分类号： B01D11/00 , A61F2/16 , C08J7/047 , C08J2383/04 , C08J2401/02
摘要： A process for removing contaminants and/or leachables from polymeric materials useful in the manufacture of biocompatible medical devices such as intraocular lenses, corneal inlays and contact lenses using continuous soxhlet extraction.
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公开(公告)号：US06762271B2
公开(公告)日：2004-07-13
申请号：US10003616
申请日：2001-11-02
IPC分类号： C08G7700
CPC分类号： C07F7/081 , Y10S623/905 , Y10S623/907
摘要： Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based silyl monomers or the copolymerization of one or more aromatic-based silyl monomers with one or more aromatic or non-aromatic non-siloxy-based monomers, hydrophobic monomers or hydrophilic monomers.
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公开(公告)号：US06657032B2
公开(公告)日：2003-12-02
申请号：US09974932
申请日：2001-10-10
申请人： David P. Vanderbilt
发明人： David P. Vanderbilt
IPC分类号： C08F22068
CPC分类号： G02B1/043 , A61L27/16 , A61L2430/16 , C08F220/26 , C08L33/02 , C08L33/14
摘要： Optically transparent, high refractive index hydrogels and intraocular lenses fabricated therefrom. The preferred hydrogels have a refractive index of 1.45 or above and a water content of approximately 5 to 30 percent by weight.
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公开(公告)号：US06329485B1
公开(公告)日：2001-12-11
申请号：US09209552
申请日：1998-12-11
申请人： David P. Vanderbilt
发明人： David P. Vanderbilt
IPC分类号： C08F22030
CPC分类号： G02B1/043 , A61L27/16 , A61L2430/16 , C08F220/26 , C08L33/02 , C08L33/14
摘要： Optically transparent, high refractive index hydrogels and intraocular lenses fabricated therefrom. The preferred hydrogels have a refractive index of 1.45 or above and a water content of approximately 5 to 30 percent by weight.
摘要翻译： 光学透明，高折射率水凝胶和由其制造的眼内透镜。 优选的水凝胶的折射率为1.45以上，水含量为约5〜30重量％。
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公开(公告)号：US5990194A
公开(公告)日：1999-11-23
申请号：US966133
申请日：1997-11-07
IPC分类号： A61L27/00 , A61F2/00 , A61F2/02 , A61F2/30 , A61K9/00 , A61K9/22 , A61K47/34 , A61L15/44 , A61L15/62 , A61L24/00 , A61L24/04 , A61L24/06 , A61L26/00 , A61L27/16 , A61L27/18 , A61L27/26 , A61L27/34 , A61L27/50 , A61L27/54 , A61L27/58 , A61K9/08
CPC分类号： A61K9/0024 , A61K47/34 , A61L15/44 , A61L15/62 , A61L24/0015 , A61L24/0026 , A61L24/0042 , A61L24/046 , A61L24/06 , A61L26/0019 , A61L26/0066 , A61L26/0076 , A61L26/009 , A61L27/16 , A61L27/18 , A61L27/26 , A61L27/34 , A61L27/50 , A61L27/54 , A61L27/58 , A61F2002/30062 , A61F2002/30583 , A61F2210/0004 , A61F2210/0085 , A61L2300/25 , A61L2300/252 , A61L2300/404 , A61L2300/406 , A61L2300/41 , A61L2300/604 , Y10S525/937
摘要： A biodegradable polymer is provided for use in providing syringeable, in-situ forming, solid biodegradable implants for animals. The polymer is placed into the animal in liquid form and cures to form the implant in-situ. A thermoplastic system to form said implant comprises the steps of dissolving a non-reactive polymer in biocompatible solvent to form a liquid, placing the liquid within the animal, and allowing the solvent to dissipate to produce the implant. An alternative, thermosetting system comprises mixing together effective amounts of a liquid acrylic ester terminated, biodegradable prepolymer and a curing agent, placing the liquid mixture within an animal and allowing the prepolymer to cure to form the implant. Both systems provide a syringeable, solid biodegradable delivery system by the addition of an effective level of biologically active agent to the liquid before injection into the body.
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