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公开(公告)号：US20160021888A1
公开(公告)日：2016-01-28
申请号：US14874940
申请日：2015-10-05
Applicant: American Sterilizer Company
Inventor： Peter A. Burke , Mark James Leggett , Michael A. Centanni
IPC: A01N59/00 , A01N37/16 , A61K9/70 , B65D75/58 , A61K33/40 , A61K9/00 , B65D75/30 , A01N25/34 , A61K31/327
CPC classification number: A01N59/00 , A01N25/34 , A01N37/16 , A61K8/0208 , A61K8/22 , A61K9/0014 , A61K9/7007 , A61K31/327 , A61K33/40 , A61K45/06 , A61L2/0088 , A61L2/186 , A61L2202/21 , A61L2202/24 , A61Q17/005 , B65D75/30 , B65D75/5805 , A61K2300/00
Abstract: This invention relates to a wipe for killing spores comprising an absorbent sheet holding an aqueous composition and a sealed package containing the absorbent sheet, wherein the aqueous composition comprises water, an antimicrobial agent and a peroxide. The invention also relates to a process for killing spores using the above-indicated wipe.
Abstract translation: 本发明涉及一种用于杀死孢子的擦拭物，其包括含有水性组合物的吸收性片材和含有该吸收性片材的密封包装，其中该水性组合物包含水，抗微生物剂和过氧化物。 本发明还涉及使用上述擦拭物杀死孢子的方法。
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公开(公告)号：US20150306266A1
公开(公告)日：2015-10-29
申请号：US14537958
申请日：2014-11-11
Applicant: American Sterilizer Company
Inventor： Peter A. Burke , Mark James Leggett , Michael A. Centanni
CPC classification number: A61L2/186 , A01N37/16 , A01N59/00 , A61L2/183 , A61L2202/24 , A01N2300/00
Abstract: This invention relates to a a process for decontaminating or sterilizing an article contaminated with spores. The process comprises contacting the spores with a liquid sterilant for a sufficient period of time to effect a desired reduction (e.g., at least a 4 log reduction) in the number of spores capable of returning to vegetative growth. The liquid sterilant may comprise water, an antimicrobial agent (e.g., peracetic acid) and a peroxide (e.g., hydrogen peroxide).
Abstract translation: 本发明涉及对被孢子污染的物品进行净化或灭菌的方法。 该方法包括使孢子与液体杀菌剂接触足够的时间以实现能够恢复营养生长的孢子数量所需的还原（例如至少4log的减少）。 液体杀菌剂可以包含水，抗微生物剂（例如过乙酸）和过氧化物（例如过氧化氢）。
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Patent Agency Ranking
公开(公告)号：US10463754B2
公开(公告)日：2019-11-05
申请号：US14537958
申请日：2014-11-11
Applicant: American Sterilizer Company
Inventor： Peter A. Burke , Mark James Leggett , Michael A. Centanni
Abstract: This invention relates to a a process for decontaminating or sterilizing an article contaminated with spores. The process comprises contacting the spores with a liquid sterilant for a sufficient period of time to effect a desired reduction (e.g., at least a 4 log reduction) in the number of spores capable of returning to vegetative growth. The liquid sterilant may comprise water, an antimicrobial agent (e.g., peracetic acid) and a peroxide (e.g., hydrogen peroxide).
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公开(公告)号：US10301631B2
公开(公告)日：2019-05-28
申请号：US16001203
申请日：2018-06-06
Applicant: American Sterilizer Company
Inventor： Phillip P. Franciskovich , Tricia A. Cregger , William A. Yirava , Peter A. Burke
IPC: C12Q1/22 , C12Q1/34 , C12Q1/68 , C12N15/75 , A61L2/28 , C12M1/34 , C12Q1/689 , C12M1/12 , C12Q1/6897 , C12N9/38
Abstract: This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for producing an indicator enzyme; a regulatory gene; and a vehicle for inserting the reporter gene and the regulatory gene in the host organism; the host organism bearing a transposable genetic element in its genome for inserting an insertion sequence in the regulatory gene; the insertion sequence comprising a transposase, a pair of terminal inverted repeat sequences, and at least one open reading frame for expressing the transposase. The vehicle may be taken up by the host organism. The insertion sequence may be inserted in the regulatory gene. The host organism may undergo sporulation to form the biological indicator. A process and an apparatus for using the biological indicator are disclosed.
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公开(公告)号：US10017772B2
公开(公告)日：2018-07-10
申请号：US15618158
申请日：2017-06-09
Applicant: American Sterilizer Company
Inventor： Phillip P. Franciskovich , Tricia A. Cregger , William A. Yirava , Peter A. Burke
IPC: C12Q1/22 , C12Q1/34 , C12Q1/68 , C12N15/75 , C12M1/12 , C12N9/38 , A61L2/28 , C12M1/34 , C12Q1/6897 , C12Q1/689
Abstract: This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for producing an indicator enzyme; a regulatory gene; and a vehicle for inserting the reporter gene and the regulatory gene in the host organism; the host organism bearing a transposable genetic element in its genome for inserting an insertion sequence in the regulatory gene; the insertion sequence comprising a transposase, a pair of terminal inverted repeat sequences, and at least one open reading frame for expressing the transposase. The vehicle may be taken up by the host organism. The insertion sequence may be inserted in the regulatory gene. The host organism may undergo sporulation to form the biological indicator. A process and an apparatus for using the biological indicator are disclosed.
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公开(公告)号：US09695428B2
公开(公告)日：2017-07-04
申请号：US15204079
申请日：2016-07-07
Applicant: American Sterilizer Company
Inventor： Phillip P. Franciskovich , Tricia A. Cregger , William A. Yirava , Peter A. Burke
CPC classification number: C12N15/75 , A61L2/28 , C12M1/34 , C12M37/06 , C12N9/2471 , C12Q1/22 , C12Q1/34 , C12Q1/689 , C12Q1/6897 , C12Y302/01023
Abstract: This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for producing an indicator enzyme; a regulatory gene; and a vehicle for inserting the reporter gene and the regulatory gene in the host organism; the host organism bearing a transposable genetic element in its genome for inserting an insertion sequence in the regulatory gene; the insertion sequence comprising a transposase, a pair of terminal inverted repeat sequences, and at least one open reading frame for expressing the transposase. The vehicle may be taken up by the host organism. The insertion sequence may be inserted in the regulatory gene. The host organism may undergo sporulation to form the biological indicator. A process and an apparatus for using the biological indicator are disclosed.
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公开(公告)号：US20150373986A1
公开(公告)日：2015-12-31
申请号：US14847022
申请日：2015-09-08
Applicant: American Sterilizer Company
Inventor： Peter A. Burke , Mark James Leggett , Michael A. Centanni
CPC classification number: A01N59/00 , A01N37/16 , A61K8/22 , A61K31/327 , A61K33/40 , A61K45/06 , A61Q11/00 , A61Q17/005 , A01N2300/00 , A61K2300/00
Abstract: This invention relates to an aqueous composition and a process for killing spores. The process may comprise contacting the spores with the aqueous composition for a sufficient period of time to effect a desired reduction (e.g., at least a 4 log reduction) in the number of spores capable of returning to vegetative growth. The aqueous composition may comprise water, an antimicrobial agent (e.g., peracetic acid) and a peroxide (e.g., hydrogen peroxide). The process may be a two-step process involving the use of a first aqueous composition, which may comprise water and the peroxide, and a second aqueous composition which may comprise water and the antimicrobial agent.
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