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公开(公告)号：US5634936A
公开(公告)日：1997-06-03
申请号：US383824
申请日：1995-02-06
CPC分类号： A61L31/16 , A61B17/0057 , A61L31/04 , A61L31/044 , A61L31/048 , A61L31/06 , A61L31/14 , A61L31/148 , A61B2017/00557 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00601 , A61B2017/00606 , A61B2017/00615 , A61L2300/412 , A61L2300/414
摘要： A device for closing off a septal defect including a polymeric self-hardening material in a specific conformation which is delivered by a catheter device to the area of defect either directly on the cardiac tissue or into a balloon which spans both surfaces of the defect, and hardened in-situ by change in pH or ionic concentration, organic solvents, by permeation of a secondary material capable of precipitation, or by exposure to heat, light or laser energy. In blood, the device may be hardened through photopolymerization or a cooperative effect of coagulation, precipitation or ionization. The device can be made of biodegradable material impregnated with growth factors, mitogenic factors or other determinants which can improve tissue growth such that tissue ingrowth can occur over a period of time. The catheter itself may be an ultrasonic imaging catheter.
摘要翻译： 一种用于闭合中隔缺损的装置，其包括特定构象的聚合物自硬化材料，其通过导管装置直接在心脏组织或横跨缺损的两个表面的气球中传送到缺陷区域;以及 通过pH或离子浓度的变化，有机溶剂，能够沉淀的二次材料的渗透，或通过暴露于热，光或激光能量而原位硬化。 在血液中，可以通过光聚合或凝结，沉淀或离子化的协同作用使装置硬化。 该装置可以由浸有生长因子，促有丝分裂因子或其他决定因素的可生物降解材料制成，其可以改善组织生长，使得组织向内生长可以在一段时间内发生。 导管本身可以是超声成像导管。
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公开(公告)号：US5551954A
公开(公告)日：1996-09-03
申请号：US322107
申请日：1994-10-12
CPC分类号： A61F2/82 , A61F2/88 , A61L31/148 , A61L31/16 , A61F2/958 , A61F2210/0004 , A61F2210/0023 , A61F2210/0076 , A61F2250/0067 , A61L2300/604 , A61L2300/622
摘要： A stent includes a main body of a generally tubular shape having an exterior surface, a cambered interior surface, a leading end and a trailing end. The main body has substantially the same thickness at the leading end as at the trailing end. The stent may be made of a biodegradable material having a rate of degradation and including a drug releasable at a rate controlling the rate of degradation of the biodegradable material.
摘要翻译： 支架包括具有外表面，弧形内表面，前端和后端的大体管状形状的主体。 主体在尾端的前端具有基本上相同的厚度。 支架可以由具有降解速率的生物可降解材料制成，并且包括以控制可生物降解材料的降解速率的速率释放的药物。
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公开(公告)号：US4234972A
公开(公告)日：1980-11-25
申请号：US917646
申请日：1978-06-21
申请人： Larry L. Hench , Paul J. Buscemi
发明人： Larry L. Hench , Paul J. Buscemi
CPC分类号： A61L27/306 , A61C8/0012 , A61F2/30767 , C03C4/0007 , C23D5/04 , A61C8/0013 , A61F2310/00592 , A61F2310/00928
摘要： A prosthesis for cement-free bonding to bone comprising a metal substrate coated with a biologically active glass or glass-ceramic of uniform composition and thermal coefficient of expansion and free of flaws resulting from thermo-mechanical stresses, the glass coating being bonded to the metal substrate by ion diffusion of the interface wherein the thermal coefficients of expansion of the metal substrate and the glass or glass-ceramic coating are substantially different.
摘要翻译： 一种用于与骨头无粘结的假体，包括用生物活性玻璃或玻璃陶瓷涂覆的具有均匀组成和热膨胀系数的金属基底，并且没有由热机械应力引起的缺陷，玻璃涂层结合到金属 衬底通过界面的离子扩散，其中金属衬底和玻璃或玻璃 - 陶瓷涂层的热膨胀系数基本上不同。
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公开(公告)号：US09510922B2
公开(公告)日：2016-12-06
申请号：US13113946
申请日：2011-05-23
CPC分类号： A61F2/00 , A61F5/566 , A61F2210/0004
摘要： An implant for treating an obstructive airway disorder includes an elongate implant body configured for implanting in airway-interface tissue. At least a portion of the elongate body carries a light transmission material for permitting light transmission therein. Systems and methods of treating an airway disorder including implanting an implant in an airway-interface tissue are also provided.
摘要翻译： 用于治疗阻塞性气道障碍的植入物包括构造成用于植入气道界面组织中的细长植入体。 细长体的至少一部分携带用于允许光透射的透光材料。 还提供了治疗气道障碍的系统和方法，包括将植入物植入气道界面组织中。
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公开(公告)号：US20140007885A1
公开(公告)日：2014-01-09
申请号：US13935052
申请日：2013-07-03
IPC分类号： A61F5/56
CPC分类号： A61F5/566
摘要： Methods for treating sleep apnea. A method includes implanting at least first and second elongated implants in a tongue or soft palate of a patient, wherein each of the first and second implants is configured to have a first, expanded configuration and a second, contracted configuration, wherein implanting comprises implanting the first and second implants having their first, expanded configurations. The invention also provides systems for treating sleep apnea that can be used with the methods.
摘要翻译： 睡眠呼吸暂停治疗方法 一种方法包括将至少第一和第二细长植入物植入患者的舌或软腭中，其中第一和第二植入物中的每一个被配置为具有第一扩张构型和第二收缩构造，其中植入包括植入 第一和第二植入物具有其第一，扩展的构型。 本发明还提供了用于治疗可与该方法一起使用的睡眠呼吸暂停的系统。
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公开(公告)号：US20140000631A1
公开(公告)日：2014-01-02
申请号：US13539081
申请日：2012-06-29
申请人： Edward M. GILLIS , Csaba TRUCKAI , Paul J. Buscemi
发明人： Edward M. GILLIS , Csaba TRUCKAI , Paul J. Buscemi
CPC分类号： A61F5/566 , A61F2/00 , A61F2210/0004 , A61F2250/0018 , Y10T29/49826
摘要： Methods of maintaining airway patency in an airway of a patient. A method includes the steps of wrapping a bioerodable material at least partway around an axis to create a wound bioerodable implant, and coupling two points on the bioerodable material to each other. The invention also provides systems for maintaining airway patency in an airway of a patient that may be used with the methods.
摘要翻译： 维持患者气道通气通畅的方法。 一种方法包括以下步骤：将至少一部分可生物侵蚀的材料缠绕在轴线周围以产生缠绕的可生物侵蚀的植入物，并将可生物侵蚀的材料上的两个点彼此连接。 本发明还提供了可以与该方法一起使用的用于维持患者气道中的气道通畅的系统。
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公开(公告)号：US20120017919A1
公开(公告)日：2012-01-26
申请号：US13188385
申请日：2011-07-21
IPC分类号： A61F5/56
CPC分类号： A61F5/566
摘要： A method of treating an airway disorder includes placing an implant in a patient's tongue, wherein the implant has first and second end portions that attach to tissue, and a tensioned medial portion between the first and second ends. The medial portion is configured to apply a pressure of less than a predetermined amount. Device systems associated with such methods are also provided.
摘要翻译： 治疗气道障碍的方法包括将植入物放置在患者舌头中，其中植入物具有连接到组织的第一和第二端部以及在第一和第二端之间的张紧的中间部分。 内侧部分构造成施加小于预定量的压力。 还提供了与这种方法相关联的设备系统。
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公开(公告)号：US07806925B2
公开(公告)日：2010-10-05
申请号：US11041027
申请日：2005-01-21
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61F2/88 , A61F2/958 , A61F2210/0004 , A61F2210/0023 , A61F2250/0067 , A61F2250/0068 , A61L31/041 , A61L31/044 , A61L31/047 , A61L31/148 , A61L31/16 , A61L2300/42 , A61L2300/604 , A61L2300/606 , A61L2300/622 , Y10S623/901 , C08L67/04
摘要： A stent includes a main body of a generally tubular shape for insertion into a lumen of a vessel of a living being. The tubular main body includes a substantially biodegradable matrix having collagen IV and laminin that enclose voids within the matrix. The tubular main body also includes a biodegradable strengthening material in contact with the matrix to strengthen the matrix. The tubular main body is essentially saturated with drugs.
摘要翻译： 支架包括用于插入活体血管内腔的大体管状形状的主体。 管状主体包括基本上可生物降解的基质，其具有包围基质内的空隙的胶原IV和层粘连蛋白。 管状主体还包括与基质接触以增强基质的可生物降解的强化材料。 管状主体基本上被药物饱和。
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公开(公告)号：US20080078412A1
公开(公告)日：2008-04-03
申请号：US11706729
申请日：2007-02-15
IPC分类号： A61F5/56
CPC分类号： A61F5/566 , A61B2017/248
摘要： A patient's obstructive sleep apnea is treated by identifying a patient with sleep apnea attributable at least in part to movement of a base of a tongue of the patient toward a pharyngeal wall of the patient. The tongue is stiffened by an implant sized to be placed within the tongue. A distal portion of the implant is sized to extend within the tongue from a first end near a mandibular-geniohyoid interface to a second end near a base of the tongue. A proximal portion is attached to the first end and adapted to be secured to a jaw bone of the patient following a period of healing after placement of the implant in the tongue.
摘要翻译： 患者的阻塞性睡眠呼吸暂停通过识别至少部分地归因于患者的舌头的基部朝向患者的咽壁的移动而患有睡眠呼吸暂停的患者来治疗。 舌头由被放置在舌头内的植入物硬化。 植入物的远端部分的尺寸被设计成在舌下从第一端附近的下颌骨 - 基底膜界面延伸到靠近舌头基部的第二端。 近端部分附接到第一端并且适于在将植入物放置在舌头中之后经过愈合期后固定到患者的颚骨上。
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公开(公告)号：US06299597B1
公开(公告)日：2001-10-09
申请号：US08978190
申请日：1997-11-25
申请人： Paul J. Buscemi , Fertac Bilge , Thomas J. Holman
发明人： Paul J. Buscemi , Fertac Bilge , Thomas J. Holman
IPC分类号： A61M2900
CPC分类号： A61F2/82 , A61F2250/0067 , A61M25/1002 , A61M25/104 , A61M29/02 , A61M2025/105 , A61M2025/1052
摘要： Percutaneous repair of cardiovascular anomalies via the introduction of a photoactivated biopolymer introduced to the affected site via a catheter system.
摘要翻译： 通过引入通过导管系统引入受影响部位的光活化生物聚合物来经皮修复心血管异常。
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