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公开(公告)号:US20090186780A1
公开(公告)日:2009-07-23
申请号:US12349299
申请日:2009-01-06
Applicant: June-Young Lee , Dong-Ho Lee , Nam Huh
Inventor: June-Young Lee , Dong-Ho Lee , Nam Huh
IPC: C40B60/12
CPC classification number: G01N21/6454 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00617 , B01J2219/00653 , B01J2219/00704 , B01J2219/00722
Abstract: A biochip for qualitatively analyzing a biological sample using probes includes a probe cell array comprising a plurality of probe cells capable of coupling with biomolecules of a biological sample, an optical sensor for detecting optical signals from probe cells selectively coupling with the biomolecules of the biological sample and converting the optical signals to digital electrical signals, and a memory cell array for storing the digital electrical signals.
Abstract translation: 用于使用探针定性分析生物样品的生物芯片包括探针单元阵列,其包括能够与生物样品的生物分子偶联的多个探针细胞,用于检测来自与生物样品的生物分子选择性偶联的探针细胞的光学信号的光学传感器 并将光信号转换为数字电信号,以及用于存储数字电信号的存储单元阵列。
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公开(公告)号:US20090186777A1
公开(公告)日:2009-07-23
申请号:US12357270
申请日:2009-01-21
Applicant: June-Young LEE , Dong-Ho LEE , Jae-Young KIM
Inventor: June-Young LEE , Dong-Ho LEE , Jae-Young KIM
IPC: C40B40/04
CPC classification number: C40B99/00 , B01J19/0046 , B01J2219/00317 , B01J2219/00527 , B01J2219/00596 , B01J2219/00605 , B01J2219/00617 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00659 , B01J2219/00662 , B01J2219/0072 , B01L3/5085 , B01L2200/10 , B01L2200/12 , B01L2300/0636 , B01L2300/0829 , B01L2300/0893
Abstract: A biochip can include a substrate having surface features of protrusions or recesses and probes coupled to each of the surface features. A biochip can include a substrate having recess regions and probes coupled to each of the recess regions, wherein a surface of each of the recess regions has convexes and concaves. A biochip can include a substrate having recess regions, immobilization layers conformally formed in the recess regions, and probes coupled onto each of the immobilization layers. The biochip can be divided into probe cell regions to which the probes are coupled, wherein the recess regions are formed in the probe cell regions, and non-probe cell regions, wherein a surface of each of the non-probe cell regions can include an exposed surface of the substrate.
Abstract translation: 生物芯片可以包括具有突起或凹陷的表面特征的基底和耦合到每个表面特征的探针。 生物芯片可以包括具有凹陷区域的衬底和耦合到每个凹陷区域的探针,其中每个凹陷区域的表面具有凸起和凹陷。 生物芯片可以包括具有凹陷区域的基底,在凹陷区域中保形地形成的固定层,以及耦合到每个固定层上的探针。 生物芯片可以分为与探针连接的探针细胞区域,其中在探针细胞区域中形成凹陷区域,以及非探针细胞区域,其中每个非探针细胞区域的表面可以包括 曝光的表面。
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公开(公告)号:US20090075414A1
公开(公告)日:2009-03-19
申请号:US12194459
申请日:2008-08-19
Applicant: June-Young Lee , Dong-Ho Lee , Hyeong-Jun Kim
Inventor: June-Young Lee , Dong-Ho Lee , Hyeong-Jun Kim
IPC: H01L21/50
CPC classification number: C40B80/00 , B01J19/0046 , B01J2219/00432 , B01J2219/00441 , B01J2219/00443 , B01J2219/00531 , B01J2219/0056 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00617 , B01J2219/00621 , B01J2219/00637 , B01J2219/00659 , B01J2219/00662 , B01J2219/00693
Abstract: A method of fabricating a biochip and a biochip fabricated by the method are provided. The method can include providing a substrate including a plurality of first areas separated from each other by a second area, forming a plurality of activation patterns on each of the first areas, coupling a plurality of probes to each of the activation patterns, and cutting the substrate along the second area to form a plurality of chips.
Abstract translation: 提供了一种通过该方法制造生物芯片和生物芯片的方法。 该方法可以包括提供包括通过第二区域彼此分离的多个第一区域的衬底,在每个第一区域上形成多个激活图案,将多个探针耦合到每个激活模式,并切割 基板沿着第二区域形成多个芯片。
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公开(公告)号:US20090018035A1
公开(公告)日:2009-01-15
申请号:US12217169
申请日:2008-07-02
Applicant: June-Young Lee , Dong-Ho Lee
Inventor: June-Young Lee , Dong-Ho Lee
CPC classification number: C40B60/12 , B01L3/508 , B01L2200/16 , B01L2200/18 , B01L2300/047 , B01L2300/0636
Abstract: A package having an improved yield is provided. The package includes a support on which a plurality of biochips are disposed, and a cover bonded to the support and defining a reaction space for each of the plurality of biochips together with the support, the cover including at least one inlet/outlet.
Abstract translation: 提供了具有提高的产量的包装。 该包装包括一个支撑件,多个生物芯片设置在该支架上,盖子与该支撑件结合并且与该支撑件一起为多个生物芯片中的每一个形成反应空间,该盖子包括至少一个入口/出口。
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