公开(公告)号：US20100076414A1

公开(公告)日：2010-03-25

申请号：US12589847

申请日：2009-10-28

Applicant: Leroy E. Hood ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Robert Langer ,  Clarence T. Tegreene ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

Inventor： Leroy E. Hood ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Robert Langer ,  Clarence T. Tegreene ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

IPC: A61M31/00 ,  G05D11/00 ,  G05D7/06 ,  G06F21/20

CPC classification number: A61K9/0009 ,  A61M5/14276 ,  A61M5/145 ,  A61M5/172 ,  A61M5/1723 ,  A61M31/002 ,  A61M2005/14513 ,  A61M2205/0266 ,  A61M2205/0288 ,  A61M2205/3523 ,  A61M2205/3569 ,  A61M2205/36

Abstract: Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.

公开(公告)号：US20100069606A1

公开(公告)日：2010-03-18

申请号：US12283908

申请日：2008-09-15

Applicant: Mahalaxmi Gita Bangera ,  Ed Harlow ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

Inventor： Mahalaxmi Gita Bangera ,  Ed Harlow ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

IPC: C07K2/00 ,  C07K16/00 ,  C07H1/00 ,  C07H21/04 ,  C07D323/00 ,  C07C69/00 ,  C07C229/00 ,  C07C49/00 ,  C07C47/00 ,  C07C43/00 ,  C07K14/42

CPC classification number: C07K16/32 ,  A61K38/1703 ,  A61K38/1732 ,  A61K47/60 ,  A61K47/6871 ,  A61K47/6901 ,  B82Y5/00 ,  B82Y15/00 ,  B82Y30/00 ,  B82Y40/00 ,  C01B21/0648 ,  C01B32/168 ,  C01B32/174 ,  C01B2202/02 ,  C01B2202/34 ,  C01B2202/36 ,  C01P2004/13 ,  Y02A50/473 ,  Y10S977/743 ,  Y10S977/75 ,  Y10S977/762 ,  Y10S977/788 ,  Y10S977/795 ,  Y10S977/848 ,  Y10S977/896 ,  Y10S977/915

Abstract: Devices, compositions, and methods are described which provide a tubular nanostructure targeted to a lipid bilayer membrane. The targeted tubular nanostructure can have a surface region configured to pass through a lipid bilayer membrane of a cell, a hydrophobic surface region flanked by two hydrophilic surface regions configured to form a pore in a lipid bilayer membrane of a cellular organelle, and at least one ligand configured to bind one or more cognates on the lipid bilayer membrane of the cellular organelle. The target cell can be, for example, a tumor cell, an infected cell, or a diseased cell in a subject. The tubular nanostructure can form a pore in the lipid bilayer membrane of the cellular organelle, e.g., mitochondria, which can permit transit or translocation of at least one compound across the membrane and cause cell death of the target cell.

Abstract translation: 描述了提供靶向脂质双层膜的管状纳米结构的装置，组合物和方法。 目标管状纳米结构可以具有被配置为穿过细胞的脂质双层膜的表面区域，侧壁有两个亲水性表面区域的疏水性表面区域，所述疏水性表面区域配置成在细胞器官细胞器的脂质双层膜中形成孔，以及至少一个 配体被配置为结合细胞器的脂质双层膜上的一个或多个同源物。 靶细胞可以是例如受试者中的肿瘤细胞，感染细胞或患病细胞。 管状纳米结构可以在细胞器（例如线粒体）的脂质双层膜中形成孔，其可以允许至少一种化合物跨过膜的转运或易位并导致靶细胞的细胞死亡。

公开(公告)号：US07679066B2

公开(公告)日：2010-03-16

申请号：US12215064

申请日：2008-06-24

Applicant: Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr.

Inventor： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr.

IPC: G01J1/42

CPC classification number: G01J1/4228 ,  G01J1/0448 ,  G01J3/02 ,  G01J3/0237 ,  G01J3/0256 ,  G01J3/2803 ,  G01J3/36 ,  G01J9/00

Abstract: A waveform detector may include multiple stages.

公开(公告)号：US20100042669A1

公开(公告)日：2010-02-18

申请号：US12454113

申请日：2009-05-12

Applicant: Alexander J. Cohen ,  Edward K.Y. Jung ,  Royce A. Levien ,  Robert W. Lord ,  Mark A. Malamud ,  William H. Mangione-Smith ,  John D. Rinaldo, JR. ,  Clarence T. Tegreene

Inventor： Alexander J. Cohen ,  Edward K.Y. Jung ,  Royce A. Levien ,  Robert W. Lord ,  Mark A. Malamud ,  William H. Mangione-Smith ,  John D. Rinaldo, JR. ,  Clarence T. Tegreene

IPC: G06F15/16

CPC classification number: G06Q10/00

Abstract: Methods and systems for modifying illusory user identification characteristics are provided.

Abstract translation: 提供了用于修改虚幻用户识别特征的方法和系统。

公开(公告)号：US07660385B2

公开(公告)日：2010-02-09

申请号：US11906150

申请日：2007-09-28

Applicant: Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

Inventor： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC: G01N23/223

CPC classification number: G01N23/223 ,  A61B6/00 ,  A61B6/4021 ,  A61B6/4291 ,  A61B6/485 ,  G01N2223/076 ,  G01N2223/506

Abstract: One aspect can relate to determining a total time of flight that indicates an at least one applied duration and an at least one induced duration, wherein the at least one applied duration describes the time for an at least some pulse-type input energy to be applied from a transmission location to an at least one X-ray fluorescing event in the at least some matter of the at least the portion of the at least one individual, and wherein the at least one induced duration describes the time for an at least one induced X-ray fluorescing photon, to travel from the at least one X-ray fluorescing event in the at least some matter of the at least the portion of the at least one individual to a location where the at least one induced X-ray fluorescing photon is received at least partially by a detecting the at least one induced X-ray fluorescing photon. The aspect can relate to determining a location information of the at least one X-ray fluorescing event in the at least some matter of the at least the portion of the at least one individual based at least partially on the total time of flight.

Abstract translation: 一个方面可以涉及确定指示至少一个施加持续时间和至少一个诱导持续时间的总飞行时间，其中所述至少一个施加的持续时间描述了应用至少一些脉冲型输入能量的时间 在所述至少一个个体的至少一部分的至少一些物质中从透射位置到至少一个X射线荧光事件，并且其中所述至少一个诱导持续时间描述了至少一个诱导的时间 X射线荧光光子从所述至少一个个体的至少一部分中的至少一些物质中的至少一个X射线荧光事件行进到至少一个诱导的X射线荧光光子的位置 至少部分地通过检测至少一个诱导的X射线荧光光子被接收。 该方面可以涉及至少部分地基于总飞行时间来确定至少一个个体的至少一部分的至少一些事件中的至少一个X射线荧光事件的位置信息。

公开(公告)号：US20100007765A1

公开(公告)日：2010-01-14

申请号：US12218230

申请日：2008-07-11

Applicant: Nathan P. Myhrvold ,  Clarence T. Tegreene

Inventor： Nathan P. Myhrvold ,  Clarence T. Tegreene

IPC: H04N9/73 ,  G06K9/00

CPC classification number: H04N9/045 ,  H04N5/2256 ,  H04N9/735

Abstract: Systems and methods for modifying a color image of a scene are provided. The systems and methods involve illuminating at least a portion of the scene with a light having a known spectral power distribution, and detecting a finite number of spectral components of light received from the scene under such illumination. The detected values of spectral components of light received from the scene are used to modify the color image or rendition of the scene.

公开(公告)号：US20090327150A1

公开(公告)日：2009-12-31

申请号：US12221465

申请日：2008-07-31

Applicant: Gary W. Flake ,  Royce A. Levien ,  Robert W. Lord ,  William Henry Mangione-Smith ,  Richard F. Rashid ,  Clarence T. Tegreene ,  Lowell L. Wood, JR.

Inventor： Gary W. Flake ,  Royce A. Levien ,  Robert W. Lord ,  William Henry Mangione-Smith ,  Richard F. Rashid ,  Clarence T. Tegreene ,  Lowell L. Wood, JR.

IPC: G06Q40/00 ,  H04L9/00 ,  G06F17/30

CPC classification number: G06Q10/0637 ,  G06Q30/02 ,  G06Q40/00 ,  G06Q50/188

Abstract: Systems and methods for data brokering, and more specifically, data brokering regarding a data provider's search-related activities are described. In particular implementations, various aspects of arranging for compensation to be received from the data consumer in exchange for at least one of installation of or access of a data tracking component related to at least one user interface associated with the data provider, are described.

Abstract translation: 描述了数据中介的系统和方法，更具体地说，涉及数据提供者的搜索相关活动的数据中介。 在具体实现中，描述了安排从数据消费者接收补偿的各个方面，以换取与与数据提供者相关联的至少一个用户界面相关的数据跟踪组件的安装或访问中的至少一个。

公开(公告)号：US20090321620A1

公开(公告)日：2009-12-31

申请号：US11263539

申请日：2005-10-31

Applicant: W. Daniel Hillis ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Lowell L. Wood, JR.

Inventor： W. Daniel Hillis ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Lowell L. Wood, JR.

IPC: H01L31/042 ,  G02F1/35 ,  G01J3/50 ,  G02F1/355

CPC classification number: H01Q3/2676 ,  B82Y20/00 ,  G02F2202/36 ,  G02F2203/10 ,  G02F2203/13 ,  H01L31/101 ,  H04B10/1121

Abstract: An optical antenna assembly including multiple optical antenna elements, each of the optical antenna elements are arranged in a regular pattern and carried by a supporting body. The regular pattern of the plurality of optical antenna elements is nonuniform. Certain ones of the optical antenna elements are configured to respond to the one or more waves of light.

Abstract translation: 一种包括多个光天线元件的光天线组件，每个光天线元件以规则图案布置并由支撑体承载。 多个光学天线元件的规则图案是不均匀的。 光学天线元件中的某些被配置为响应一个或多个光波。

公开(公告)号：US20090321427A1

公开(公告)日：2009-12-31

申请号：US12184248

申请日：2008-07-31

Applicant: Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Lowell L. Wood, JR.

Inventor： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Lowell L. Wood, JR.

IPC: H05B6/68

CPC classification number: H05B6/6455 ,  H05B6/6447 ,  H05B6/705 ,  H05B6/72 ,  Y02B40/146

Abstract: Generally and not exclusively, a microwave cooking oven to cook food in a microwave chamber includes at least one array of radiation detectors. An exemplary method includes sensing an optical depth of the item along each of multiple beam paths from at least two sides of the item, and mapping isothermal regions in the interior of the item 3-dimensionally based on the sensing. Another exemplary method includes sensing a microwave power representing a value of a heatability property for each of multiple regions of the same item, and applying a different measure of the microwave power to each of the different regions according to the value of the heatability property in each individual region. Yet another exemplary method includes sensing different frequencies of the microwave power in the microwave chamber, and changing the frequency of the microwave power for heating the item, as the item undergoes heating.

Abstract translation: 通常而不是排他地，微波烹饪炉在微波室中烹饪食物包括至少一个辐射检测器阵列。 一种示例性的方法包括：从项目的至少两侧沿着多条光束路径中的每一条路径检测物品的光学深度，以及基于感测三维地映射物品内部的等温区域。 另一个示例性方法包括感测表示相同项目的多个区域中的每个区域的可热性属性的值的微波功率，并且根据每个不同区域中的可热性属性的值，对每个不同区域应用微波功率的不同测量 个别地区。 另一示例性方法包括：在物品经受加热时，检测微波功率在微波室中的不同频率，以及改变用于加热物品的微波功率的频率。

公开(公告)号：US07638090B2

公开(公告)日：2009-12-29

申请号：US11411207

申请日：2006-04-25

Applicant: Roderick A. Hyde ,  Edward K. Y. Jung ,  Royce A. Levien ,  Robert W. Lord ,  Mark A. Malamud ,  John D. Rinaldo, Jr. ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr.

Inventor： Roderick A. Hyde ,  Edward K. Y. Jung ,  Royce A. Levien ,  Robert W. Lord ,  Mark A. Malamud ,  John D. Rinaldo, Jr. ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr.

IPC: A61L2/00

CPC classification number: A61L2/10 ,  A61L2/07 ,  A61L2/08 ,  A61L2/20 ,  A61L2/24

Abstract: Methods and systems for surveying and sterilizing one or more areas or one or more portions of one or more areas are described.

Abstract translation: 描述了用于对一个或多个区域的一个或多个区域或一个或多个部分进行测量和灭菌的方法和系统。