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    CONTROLLER FOR ULTRAFILTRATION BLOOD CIRCUIT WHICH PREVENTS HYPOTENSION BY MONITORING OSMOTIC PRESSURE IN BLOOD
    11.
    发明申请
    CONTROLLER FOR ULTRAFILTRATION BLOOD CIRCUIT WHICH PREVENTS HYPOTENSION BY MONITORING OSMOTIC PRESSURE IN BLOOD 有权
    用于通过监测血液中的压力来预防血压的超声波血液循环的控制器

    公开(公告)号：US20090024070A1

    公开(公告)日：2009-01-22

    申请号：US12172303

    申请日：2008-07-14

    申请人： Mark Gelfand ,  John J. O'Mahony ,  Howard R. Levin

    发明人： Mark Gelfand ,  John J. O'Mahony ,  Howard R. Levin

    IPC分类号： B01D61/32 ,  B01D61/22 ,  B01D61/12 ,  A61M1/34

    CPC分类号： A61M1/34 ,  A61M1/1611 ,  A61M1/3403 ,  A61M1/341 ,  A61M1/3609 ,  A61M1/3639 ,  A61M1/367 ,  A61M2205/3306 ,  A61M2205/3331 ,  A61M2205/3344 ,  A61M2205/3375 ,  A61M2205/50 ,  A61M2230/20

    摘要： A device for continuously measuring osmotic pressure of blood flowing through an extracorporeal blood circuit including: a blood passage further comprising a withdrawal blood passage connectable to a blood vessel in a patient and an infusion blood passage connectable to a blood vessel in a patient; a filter further comprising a filtrate chamber, a blood chamber and a permeable membrane separating the filtrate chamber and blood chamber, wherein the blood chamber is in fluid communication with the blood passage; a pressure sensor measuring a pressure difference between the filtrate chambers and the blood chamber, and a controller receiving a pressure signal from the pressure sensor, determining an osmotic pressure across the permeable membrane of the filter, and adjusting a rate of removal of fluid from blood in the filter if the determined osmotic pressure level varies from a predetermined osmotic pressure setting.

    摘要翻译： 一种用于连续测量流过体外血液循环的血液的渗透压的装置，包括：血液通道，其还包括可连接到患者血管的抽血血道和可连接到患者血管的输注血液通道; 过滤器还包括滤液室，血液室和分离滤液室和血液室的可渗透膜，其中血液室与血液通道流体连通; 测量滤液室和血液室之间的压力差的压力传感器，以及接收来自压力传感器的压力信号的控制器，确定过滤器的渗透膜上的渗透压，以及调节从血液中去除流体的速率 如果确定的渗透压水平从预定的渗透压设定变化，则在过滤器中。

    Controller for ultrafiltration blood circuit which prevents hypotension by monitoring osmotic pressure in blood
    13.
    发明授权
    Controller for ultrafiltration blood circuit which prevents hypotension by monitoring osmotic pressure in blood 有权
    用于超滤血液回路的控制器，通过监测血液中的渗透压来预防低血压

    公开(公告)号：US07399289B2

    公开(公告)日：2008-07-15

    申请号：US10648233

    申请日：2003-08-27

    申请人： Mark Gelfand ,  John J. O'Mahony ,  Howard R. Levin

    发明人： Mark Gelfand ,  John J. O'Mahony ,  Howard R. Levin

    IPC分类号： A61M37/00 ,  C02F1/44

    CPC分类号： A61M1/34 ,  A61M1/1611 ,  A61M1/3403 ,  A61M1/341 ,  A61M1/3609 ,  A61M1/3639 ,  A61M1/367 ,  A61M2205/3306 ,  A61M2205/3331 ,  A61M2205/3344 ,  A61M2205/3375 ,  A61M2205/50 ,  A61M2230/20

    摘要： A method and system for the extracorporeal treatment of blood to remove fluid from the fluid overloaded patient is disclosed that non-invasively measures osmotic pressure across a filter membrane of a blood filter. The filter is permeable to water and electrolytes, but not to blood protein. The osmotic pressure indicates the protein concentration in the blood. Osmotic pressure is used to detect when hypotension is about to occur in a patient, as a result of excessive blood volume reduction during treatment of the blood. Using the osmotic pressure measurement as a feedback signal, the rate of fluid extraction is automatically controlled to achieve the desired clinical outcome and avoid precipitating a hypotensive crisis in the patient.

    摘要翻译： 公开了一种用于体外处理血液以从流体过载的患者中去除流体的方法和系统，其非侵入性地测量穿过血液过滤器的过滤膜的渗透压。 过滤器对水和电解质是可渗透的，而不是血液蛋白质。 渗透压表示血液中的蛋白质浓度。 渗透压用于检测在治疗血液期间血容量减少过多时患者何时会出现低血压。 使用渗透压测量作为反馈信号，自动控制流体提取的速率以达到期望的临床结果，并避免引起患者的低血压危象。

    Method and apparatus for purified pulse peritoneal dialysis using a single pump
    20.
    发明授权
    Method and apparatus for purified pulse peritoneal dialysis using a single pump 失效
    使用单个泵进行纯化脉冲腹膜透析的方法和装置

    公开(公告)号：US5641405A

    公开(公告)日：1997-06-24

    申请号：US613777

    申请日：1996-02-28

    申请人： Prakash R. Keshaviah ,  Paul Frederick Emerson ,  Jian Ruan

    发明人： Prakash R. Keshaviah ,  Paul Frederick Emerson ,  Jian Ruan

    IPC分类号： A61M1/16 ,  A61M1/28

    CPC分类号： A61M1/28 ,  A61M1/1611 ,  A61M1/1643 ,  A61M1/281 ,  A61M1/1696 ,  A61M2205/3393 ,  Y10S210/929

    摘要： The present invention provides an improved peritoneal dialysis method and system. The system comprises a single catheter that is placed in the patient, a source of dialysate, and a diatyzer in fluid communication with the source of dialysate and the catheter. The system includes a single fluid pump in fluid communication with the source of dialysate and the catheter. The single pump is capable of pumping the dialysate into and out of the patient and back to the source of dialysate. The method includes the steps of placing a single catheter in a peritoneum of the patient, providing a source of dialysate, coupling the source of dialysate in fluid communication with the catheter on a single fluid circuit, pumping the dialysate from the source of dialysate into and out of the peritoneum using a single pump in the single fluid circuit.

    摘要翻译： 本发明提供了一种改进的腹膜透析方法和系统。 该系统包括放置在患者体内的单个导管，透析液源和与透析液源和导管流体连通的透析器。 该系统包括与透析液源和导管流体连通的单个流体泵。 单个泵能够将透析液泵入和流出患者并返回到透析液的来源。 该方法包括以下步骤：将单个导管放置在患者的腹膜中，提供透析液源，将透析液源与导管流体连通在单个流体回路上，将透析液从透析液源泵入和 在单个流体回路中使用单个泵在腹膜外。