公开(公告)号：US20140308709A1

公开(公告)日：2014-10-16

申请号：US14051259

申请日：2013-10-10

Applicant: Samsung Electronics Co., Ltd.

Inventor： Sea-hee KIM ,  Joo-won Rhee ,  Ko-bong Choi

IPC: C07H21/04 ,  C12P19/34

CPC classification number: C12P19/34 ,  C12N15/00 ,  C12N15/10 ,  C12Q1/6844 ,  C12Q2525/301 ,  C12Q2531/125

Abstract: Provided is a polynucleotide including, from the 3′ terminus of the polynucleotide to the 5′ terminus of the polynucleotide, a first region including a nucleotide sequence complementary to a nucleotide sequence of a portion of a target nucleic acid; a second region including a nucleotide sequence identical to a nucleotide sequence of a portion of the target nucleic acid; and a third region including a nucleotide sequence that self-hybridizes to form a stem-loop structure, and compositions, kits, and methods related thereto.

Abstract translation: 本发明提供的多核苷酸包括从多核苷酸的3'末端到多核苷酸的5'末端的第一区域，其包含与靶核酸的一部分核苷酸序列互补的核苷酸序列; 第二区域，其包含与靶核酸的一部分的核苷酸序列相同的核苷酸序列; 以及包含自体杂交以形成茎 - 环结构的核苷酸序列的第三区域，以及与其相关的组合物，试剂盒和方法。