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公开(公告)号:US20180095039A1
公开(公告)日:2018-04-05
申请号:US15122489
申请日:2015-04-22
Applicant: SHENZHEN GENORIVISION TECHNOLOGY CO., LTD.
Inventor: Peiyan CAO , Yurun LIU
IPC: G01N21/64 , H01J31/50 , G01N33/543 , G01N33/68 , H01J29/96
CPC classification number: G01N21/6486 , G01J3/0208 , G01J3/0262 , G01J3/0291 , G01J3/2803 , G01J3/4406 , G01J2003/1213 , G01N21/6428 , G01N21/6454 , G01N21/76 , G01N33/54373 , G01N33/6875 , G01N2021/6478 , G01N2201/0644 , H01J29/96 , H01J31/501
Abstract: Disclosed herein is an apparatus comprising: a plurality of locations configured to have probes attached thereto, wherein interaction between the probes and an analyte generates a signal; an optical system comprising a plurality of collimators; a sensor comprising a plurality of pixels configured to detect the signal; wherein the collimators are configured to essentially prevent light from passing if a deviation of a propagation direction of the light from an optical axis of the collimators is greater than a threshold.
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公开(公告)号:US20230345143A1
公开(公告)日:2023-10-26
申请号:US18217634
申请日:2023-07-03
Applicant: Shenzhen Genorivision Technology Co. Ltd.
Inventor: Peiyan CAO , Yurun LIU
IPC: H04N25/53 , H01L27/146 , H04N25/772
CPC classification number: H04N25/53 , H01L27/14634 , H01L27/14636 , H01L27/14641 , H04N25/772 , H01L27/14658
Abstract: Disclosed herein is a method of operating a radiation detector, comprising for i=1, . . . ,N, during a transfer period (i), electrically connecting pixel (1,i) of pixels (1,j), j=1, . . . ,N of the radiation detector to a first signal processing circuit while electrically disconnecting the other N-1 pixels of the pixels (1,j), j=1, . . . ,N from the first signal processing circuit; and for i=1, . . . ,N, during the transfer period (i), transferring electrical signals from the pixel (1,i) to the first signal processing circuit.
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公开(公告)号:US20220128697A1
公开(公告)日:2022-04-28
申请号:US17571942
申请日:2022-01-10
Applicant: Shenzhen Genorivision Technology Co. Ltd.
Inventor: Peiyan CAO , Yurun LIU
IPC: G01S17/894 , G01S7/481 , G01S7/4865 , G01B11/24
Abstract: Disclosed herein is a method of operating an apparatus which comprises (a) an image sensor comprising an array of avalanche photodiodes (APDs)(i), i=1, . . . ,N, N being a positive integer, (b) a radiation source, and (c) an optical system, the method comprising: using the radiation source to emit a pulse of illumination photons at a time point Ta; for i=1, . . . ,N, measuring a time of flight (i) from Ta to a time point Tb(i) at which a photon of the illumination photons returns to the APD (i) through the optical system after bouncing off a surface spot (i) of a targeted object corresponding to the APD (i); and determining a three-dimensional contour of the targeted objects based on the times of flights (i), i=1, . . . ,N. The optical system comprises a first cylindrical lens and a second cylindrical lens. The first cylindrical lens is positioned between the targeted objects and the second cylindrical lens.
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公开(公告)号:US20200256992A1
公开(公告)日:2020-08-13
申请号:US16857653
申请日:2020-04-24
Applicant: Shenzhen Genorivision Technology Co., Ltd.
Inventor: Peiyan CAO , Yurun LIU
IPC: G01S17/08 , G01S7/484 , G01S7/4865 , G01S7/481
Abstract: Disclosed herein is a method and apparatus for determining time of arrival of incident photons. The time of arrival may be determined with high time accuracy based on the times a voltage across a capacitor being charged by charge carriers generated from the incident photons at which the voltage reaches a plurality of thresholds, respectively, and the stable value of the voltage.
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公开(公告)号:US20190029645A1
公开(公告)日:2019-01-31
申请号:US16069919
申请日:2016-01-22
Applicant: Shenzhen Genorivision Technology Co., Ltd.
Inventor: Peiyan CAO , Lin ZHANG , Jia ZHANG
Abstract: An ultrasound imaging device, the device comprising a first chip (202) and a second chip (206), the first chip (202) receiving an ultrasound signal and generating a digital signal representative of the ultrasound signal, the ultrasound signal being an analog signal, the second chip (206) processing the digital signal from the first chip (202) for ultrasound imaging. The ultrasound imaging device has reduced power consumption. Further disclosed is a corresponding ultrasound imaging method.
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公开(公告)号:US20190011366A1
公开(公告)日:2019-01-10
申请号:US16117998
申请日:2018-08-30
Applicant: Shenzhen Genorivision Technology Co., Ltd.
Inventor: Peiyan CAO , Rui DING , Yurun LIU
Abstract: Disclosed herein is an apparatus comprising: a probe carrier comprising a plurality of optical waveguides supported on a substrate; wherein each of the plurality of optical waveguides is optically decoupled from another of the plurality of optical waveguides; wherein each of the plurality of optical waveguides comprises a surface comprising sites configured to attach a probe.
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公开(公告)号:US20190003971A1
公开(公告)日:2019-01-03
申请号:US15737812
申请日:2015-12-07
Applicant: Shenzhen Genorivision Technology Co., Ltd.
Inventor: Peiyan CAO , Yurun LIU
IPC: G01N21/64
Abstract: Disclosed herein is an apparatus comprising: a probe carrier, an optical system and a sensor; wherein the probe carrier comprises a substrate, a first layer and a second layer; wherein the substrate comprises a first surface, a second surface, one or more locations on the first surface configured to be deposit sites for one or more probes; wherein the second surface is at an opposite side of the substrate from the first surface; wherein the first layer is on the first surface of the substrate or is embedded in the substrate under the first surface; wherein the second layer is on the second surface of the substrate or is embedded in the substrate under the second surface; the first and second layers are configured to reduce crosstalk between probes at different locations.
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公开(公告)号:US20180180547A1
公开(公告)日:2018-06-28
申请号:US15309303
申请日:2015-09-14
Applicant: Shenzhen Genorivision Technology Co., Ltd.
Inventor: Peiyan CAO , Yurun LIU
IPC: G01N21/64 , C12Q1/6825
Abstract: Disclosed herein is an apparatus comprising: a probe carrier comprising: a substrate comprising with holes through a thickness of the substrate and a transparent window across an opening of each of the holes, wherein the transparent window closes the opening, wherein one or more locations on the transparent window are configured to have probes attached thereto, wherein interaction between the probes and an analyte generates a signal; an optical system comprising a plurality of collimators; a sensor configured to detect the signal; wherein the collimators can essentially prevent light from passing if a deviation of a propagation direction of the light from an optical axis of the collimators is greater than a threshold. Because the probe carrier is separate and independent from the microarray, the probe carrier may be assembled with a pre-existing microarray prior to its use, and be detached from the microarray and disposed after its use.
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公开(公告)号:US20220353443A1
公开(公告)日:2022-11-03
申请号:US17863776
申请日:2022-07-13
Applicant: Shenzhen Genorivision Technology Co. Ltd.
Inventor: Peiyan CAO , Yurun LIU
IPC: H04N5/353 , H01L27/146 , H04N5/3745
Abstract: Disclosed herein is a method of operating a radiation detector, comprising for i=1, . . . , N, during a transfer period (i), electrically connecting pixel (1,i) of pixels (1,j), j=1, . . . , N of the radiation detector to a first signal processing circuit while electrically disconnecting the other N−1 pixels of the pixels (1,j), j=1, . . . , N from the first signal processing circuit; and for i=1, . . . , N, during the transfer period (i), transferring electrical signals from the pixel (1,i) to the first signal processing circuit.
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公开(公告)号:US20220128698A1
公开(公告)日:2022-04-28
申请号:US17571959
申请日:2022-01-10
Applicant: Shenzhen Genorivision Technology Co. Ltd.
Inventor: Peiyan CAO , Yurun LIU
IPC: G01S17/894 , G01S7/481 , G01S7/4865
Abstract: Disclosed herein is a method of operating an apparatus which comprises (a) an image sensor comprising an array of avalanche photodiodes (APDs)(i), i=1, . . . , N, N being a positive integer, (b) a radiation source, and (c) an optical system, the method comprising: using the radiation source to emit a first pulse of first illumination photons at a time point T1a; for i=1, . . . , N, measuring a time of flight (1,i); for i=1, . . . , N, based on the time of flight (1,i), determining a spot distance (1,i); using the radiation source to emit a second pulse of second illumination photons at a time point T2a; for j=1, . . . , N, measuring a time of flight (2,j); for j=1, . . . , N, based on the time of flight (2,j), determining a spot distance (2,j); and for k=1, . . . , N, comparing the spot distance (1,k) and the spot distance (2,k). The optical system comprises a first cylindrical lens and a second cylindrical lens.
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