公开(公告)号：US20200249171A1

公开(公告)日：2020-08-06

申请号：US16857634

申请日：2020-04-24

Applicant: Shenzhen Genorivision Technology Co., Ltd.

Inventor： Peiyan CAO ,  Rui DING ,  Yurun LIU

IPC: G01N21/77 ,  G01N21/76 ,  G01N21/64

Abstract: Disclosed herein is an apparatus, which comprises an optical waveguide, a first and second waveguide couplers. The optical waveguide may be configured to receive light from an end surface of the optical waveguide. The first waveguide coupler may be coupled, at a first coupling strength, to a first portion of the optical waveguide. The second waveguide coupler may be coupled, at a second coupling strength, to a second portion of the optical waveguide. Attenuation of the light at the first portion is smaller than attenuation of the light at the second portion. The first coupling strength is smaller than the second coupling strength. The first waveguide coupler and the second waveguide coupler each comprises a surface comprising sites configured to attach a probe.

公开(公告)号：US20190011366A1

公开(公告)日：2019-01-10

申请号：US16117998

申请日：2018-08-30

Applicant: Shenzhen Genorivision Technology Co., Ltd.

Inventor： Peiyan CAO ,  Rui DING ,  Yurun LIU

IPC: G01N21/64 ,  G01N21/77

Abstract: Disclosed herein is an apparatus comprising: a probe carrier comprising a plurality of optical waveguides supported on a substrate; wherein each of the plurality of optical waveguides is optically decoupled from another of the plurality of optical waveguides; wherein each of the plurality of optical waveguides comprises a surface comprising sites configured to attach a probe.

公开(公告)号：US20190049407A1

公开(公告)日：2019-02-14

申请号：US16160281

申请日：2018-10-15

Applicant: Shenzhen Genorivision Technology Co., Ltd.

Inventor： Rui DING ,  Peiyan CAO

IPC: G01N27/447

Abstract: Disclosed herein is a method of electrophoresis, comprising: introducing an analyte into a channel; electrophoresing the analyte by establishing a first electric field between a first electrode upstream to the analyte and a second electrode downstream to the analyte; electrophoresing the analyte by establishing a second electric field between a third electrode upstream to the analyte and a fourth electrode downstream to the analyte; wherein the fourth electrode is downstream to the second electrode.

公开(公告)号：US20180369819A1

公开(公告)日：2018-12-27

申请号：US16117824

申请日：2018-08-30

Applicant: Shenzhen Genorivision Technology Co., Ltd.

Inventor： Rui DING ,  Peiyan CAO

IPC: B01L7/00 ,  B01L3/00

CPC classification number: B01L7/52 ,  B01L3/5027 ,  B01L3/502753 ,  B01L3/50851 ,  B01L3/50853 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/0858 ,  B01L2300/0867 ,  B01L2300/0883 ,  B01L2400/0478 ,  C12Q1/6813 ,  C12Q1/6844 ,  C12Q2565/629

Abstract: Disclosed herein is a multi-functional microfluidics device capable of isolation of nucleic acids, purification of nucleic acids, performance of Polymerase Chain Reactions (PCRs), in situ hybridization of nucleic acids, fluorescent signal detections and the like. The apparatus comprises an integration of a plurality of reagent chambers, a sample input, a reaction chamber, a detection chamber, and a waste chamber; wherein the plurality of reagent chambers is fluidly connected to the reaction chamber, and is configured to store a plurality of reagents; wherein the sample input is fluidly connected to the reaction chamber, and is configured to receive a sample; wherein the waste chamber is fluidly connect to the reaction chamber and is configured to receive a reaction waste from the reaction chamber.