公开(公告)号：US20190233788A1

公开(公告)日：2019-08-01

申请号：US16315761

申请日：2017-07-05

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sung Gap IM ,  Eun Jung LEE ,  Ji Eung BAEK ,  Young Hak CHO ,  Seung Jung YU ,  Go Ro CHOI

IPC: C12M1/22 ,  B05D7/02 ,  C08J5/18 ,  C08L57/06 ,  B05D1/00

CPC classification number: C12M23/10 ,  B05D1/60 ,  B05D7/02 ,  C08F212/36 ,  C08F226/06 ,  C08J5/18 ,  C08L25/16 ,  C08L39/08 ,  C08L57/06 ,  C08L2203/02 ,  C08L2203/16 ,  C12N5/00 ,  C12N5/0018 ,  C23C16/452

Abstract: The present invention provides a culture plate comprising a copolymer formed from a first monomer for forming a thin film having high surface free energy and a second monomer for forming a thin film having low surface free energy, a method for producing the culture plate, and a method for producing and transferring a cell aggregate in the form of a cell sheet by using the culture plate. The present invention has the effect of producing a cell aggregate in the form of a cell sheet through an easy and simple process in comparison with prior art.

公开(公告)号：US20170130195A1

公开(公告)日：2017-05-11

申请号：US15318134

申请日：2014-08-01

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sung Gap IM ,  Hak Rae LEE ,  Sang Yong JON ,  Min Suk CHOI

IPC: C12N5/00 ,  C08F30/08 ,  C09D143/04 ,  C12N5/095

CPC classification number: C12N5/0068 ,  C08F30/08 ,  C09D143/04 ,  C12M25/02 ,  C12N5/0062 ,  C12N5/0695 ,  C12N2533/30

Abstract: The present invention provides a cell culture substrate comprising a polymer formed of a cyclosiloxane compound and a manufacturing method therefor, and a method for preparing a cell spheroid type of cell aggregate or induced pluripotent stem cells using the cell culture substrate. The cell spheroid type of cell aggregate can be easily formed by culturing cells on the cell culture substrate of the present invention, and further, the cell culture substrate can be utilized as a cell culture platform for preparing the induced pluripotent stem cells.