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公开(公告)号：US20230041518A1
公开(公告)日：2023-02-09
申请号：US17379175
申请日：2021-07-19
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： A61K31/47 , A61K31/4375 , A61K31/4709 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D215/14 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号：US11116760B2
公开(公告)日：2021-09-14
申请号：US16667306
申请日：2019-10-29
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： C07D413/14 , A61K31/5377 , A61K31/47 , A61K31/4375 , A61K31/4709 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D215/14 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号：US10214519B2
公开(公告)日：2019-02-26
申请号：US15711957
申请日：2017-09-21
发明人： Jayaraman Chandrasekhar , Julian Andrew Codelli , Devan Naduthambi , Leena Patel , Stephane Perreault , Gary Phillips , Kassandra F. Sedillo , Jennifer Anne Treiberg , Joshua Van Veldhuizen , William J. Watkins
IPC分类号： C07D413/14 , A61K31/5377 , C07D417/14 , C07D405/14 , C07D409/14 , A61K45/06
摘要： The present application provides the compounds of formula I or IA or pharmaceutically acceptable salts, isomers, tautomer, or a mixture thereof, wherein s, t, m, n, R1, R2, R3, R4, R5, R6 and R7 are as described herein.
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公开(公告)号：US20180086747A1
公开(公告)日：2018-03-29
申请号：US15711957
申请日：2017-09-21
发明人： Jayaraman Chandrasekhar , Julian Andrew Codelli , Devan Naduthambi , Leena Patel , Stephane Perreault , Gary Phillips , Kassandra F. Sedillo , Jennifer Anne Treiberg , Joshua Van Veldhuizen , William J. Watkins
IPC分类号： C07D413/14 , C07D417/14 , C07D409/14 , C07D405/14 , A61K31/5377
CPC分类号： C07D413/14 , A61K31/5377 , A61K45/06 , A61K2300/00 , C07D405/14 , C07D409/14 , C07D417/14
摘要： The present application provides the compounds of formula I or IA or pharmaceutically acceptable salts, isomers, tautomer, or a mixture thereof, wherein s, t, m, n, R1, R2, R3, R4, R5, R6 and R7 are as described herein.
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公开(公告)号：US20220135561A1
公开(公告)日：2022-05-05
申请号：US17500380
申请日：2021-10-13
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： C07D471/04
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号：US20220119383A1
公开(公告)日：2022-04-21
申请号：US17289614
申请日：2019-10-29
发明人： Peter A. Blomgren , Taryn L. Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole A. Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer A. Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： C07D471/04
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号：US11224600B2
公开(公告)日：2022-01-18
申请号：US16667373
申请日：2019-10-29
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： C07D413/14 , A61K31/5377 , A61K31/343 , A61K31/353 , A61K31/357 , A61K31/416 , A61K31/4375 , A61K31/4709 , A61K31/513 , A61K31/519 , A61K31/538 , A61K31/541 , A61K45/06 , C07D295/00 , C07D307/87 , C07D319/18 , C07D405/10 , C07D407/10 , C07D471/04
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号：US11179383B2
公开(公告)日：2021-11-23
申请号：US16667572
申请日：2019-10-29
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： C07D215/02 , A61K31/47 , A61K31/352 , A61K31/4709 , A61K31/497 , A61K31/501 , A61K31/513 , A61K31/5377 , A61K31/541 , C07D215/14 , C07D311/58 , C07D401/10 , C07D403/10 , C07D405/10 , C07D413/12 , C07D413/14 , C07D417/10 , C07D471/04 , C07D519/00
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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