公开(公告)号：US20210291171A1

公开(公告)日：2021-09-23

申请号：US17162467

申请日：2021-01-29

Applicant: Berkeley Lights, Inc.

Inventor： Randall D. Lowe, JR. ,  Alexander J. Mastroianni ,  Mark P. White ,  Gregory G. Lavieu ,  Kristin G. Beaumont

IPC: B01L3/00 ,  C12M3/06 ,  B81C1/00 ,  G01N33/543

Abstract: In biosciences and related fields, it can be useful to modify surfaces of apparatuses, devices, and materials that contact biomaterials such as biomolecules and biological micro-objects. Described herein are surface modifying and surface functionalizing reagents, preparation thereof, and methods for modifying surfaces to provide improved or altered performance with biomaterials.

公开(公告)号：US10705082B2

公开(公告)日：2020-07-07

申请号：US15372094

申请日：2016-12-07

Applicant: Berkeley Lights, Inc.

Inventor： Kristin G. Beaumont ,  Peter J. Beemiller ,  Volker L. S. Kurz ,  Gregory G. Lavieu ,  Xiaohua Wang ,  Aathavan Karunakaran

IPC: B01L3/00 ,  G01N33/543 ,  G01N33/545 ,  G01N33/58

Abstract: In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. Microfluidic capture structures may be advantageously used for assays performed within the microfluidic environment, providing flexibility in assaying micro-objects such as biological cells. Assay reagents and analytes may be incorporated within the microfluidic capture structures.

公开(公告)号：US20170165667A1

公开(公告)日：2017-06-15

申请号：US15359115

申请日：2016-11-22

Applicant: Berkeley Lights, Inc.

Inventor： Kristin G. Beaumont ,  Nan-Linda Ding ,  Volker L.S. Kurz ,  Troy A. Lionberger ,  Randall D. Lowe ,  Daniele Malleo ,  Andrew W. McFarland ,  J. Tanner Nevill ,  Xiaohua Wang

IPC: B01L3/00 ,  B01J19/00 ,  G01N27/447

CPC classification number: B01L3/502753 ,  B01J19/0093 ,  B01L3/5023 ,  B01L3/502707 ,  B01L3/502738 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/16 ,  B01L2400/0424 ,  B01L2400/0677 ,  B01L2400/08 ,  G01N27/44791

Abstract: In situ-generated microfluidic isolation structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. The ability to introduce in real time, a variety of isolating structures including pens and barriers offers improved methods of micro-object manipulation in microfluidic devices. The in situ-generated isolation structures may be permanently or temporarily installed.