MULTI-LAYER WORKFLOW ARCHITECTURE
    13.
    发明申请
    MULTI-LAYER WORKFLOW ARCHITECTURE 有权
    多层工作流架构

    公开(公告)号:US20090282412A1

    公开(公告)日:2009-11-12

    申请号:US12118106

    申请日:2008-05-09

    IPC分类号: G06F9/46

    摘要: A multi-layer workflow architecture for a print shop is disclosed. The workflow architecture includes a workflow front end, service bus, and service providers. The workflow front end provides an interface to print shop operators. The service providers are each associated with a device in the print shop. The service bus represents the layer between the workflow front end and the service providers. In operation, the service providers report device capabilities for devices to the service bus. The workflow front end receives the device capabilities from the service bus, and provides the device capabilities to a user to allow the user to define a job ticket based on the device capabilities. The service bus identifies the processes defined in the job ticket, and identifies the service providers operable to provide the processes. The service bus then routes process messages to the identified service providers to execute the processes on the devices.

    摘要翻译: 公开了一种用于印刷车间的多层工作流架构。 工作流架构包括工作流前端,服务总线和服务提供商。 工作流程前端提供打印店铺运营商的界面。 服务提供商各自与打印店中的设备相关联。 服务总线表示工作流前端和服务提供商之间的层。 在运行中,服务提供商将设备的设备功能报告给服务总线。 工作流前端从服务总线接收设备功能,并向用户提供设备功能,以允许用户基于设备能力定义作业单。 服务总线识别作业传票中定义的进程,并识别可操作以提供进程的服务提供者。 然后,服务总线将处理消息路由到所标识的服务提供商,以便在设备上执行进程。

    JDF PROCESSING IN A PRINTING SYSTEM
    14.
    发明申请
    JDF PROCESSING IN A PRINTING SYSTEM 有权
    JDF在打印系统中的处理

    公开(公告)号:US20090279126A1

    公开(公告)日:2009-11-12

    申请号:US12118191

    申请日:2008-05-09

    申请人: David A. Williams

    发明人: David A. Williams

    IPC分类号: G06K15/00

    摘要: Print controllers and associated methods of processing JDF job tickets in a printing system are disclosed. A print controller in one embodiment includes a storage system that receives a printable file from a host system, and stores the printable file. The print controller further comprises a JDF interpreter that receives a Job Definition Format (JDF) job ticket that is associated with the printable file from the host system. The JDF interpreter parses the JDF job ticket to identify printing parameters defined for the printable file. The JDF interpreter then issues device control commands for the printing parameters in the JDF job ticket. Thus, JDF job ticket processing is performed in the printing system instead of in the host system.

    摘要翻译: 公开了打印控制器和在打印系统中处理JDF作业单的相关方法。 一个实施例中的打印控制器包括从主机系统接收可打印文件并存储可打印文件的存储系统。 打印控制器还包括JDF解释器,其从主机系统接收与可打印文件相关联的作业定义格式(JDF)作业传票。 JDF解释器解析JDF作业单以识别为可打印文件定义的打印参数。 JDF解释器然后在JDF作业单中发出打印参数的设备控制命令。 因此,在打印系统中而不是在主机系统中执行JDF作业传票处理。

    CHIMERIC PEPTIDES FOR THE REGULATION OF GTPASES
    15.
    发明申请
    CHIMERIC PEPTIDES FOR THE REGULATION OF GTPASES 有权
    用于调整GTPASES的CHIMERIC PEPTIDES

    公开(公告)号:US20090203617A1

    公开(公告)日:2009-08-13

    申请号:US12348762

    申请日:2009-01-05

    摘要: Chimeric peptides or fusion proteins are disclosed that include a RhoGAP activity domain and at least one specificity domain that targets a specific Rho protein. The fusion proteins can be used to inhibit any GTPase activity within a cell. The fusion proteins are particularly advantageous for the treatment of cancer. The present invention generally relates to chimeric peptides capable of regulating GTPases, and more particularly, to methods of targeting individual GTPases by using GTPase-activating proteins. Such proteins may be used for the treatment of cancers and other GTPase-related diseases. This invention relates to nucleic acid molecules and the encoded GTPase activating proteins, and variants thereof, and to the use of these molecules in the characterization, diagnosis, prevention, and treatment of cell signaling, immune, and cell proliferative disorders, particularly cancer. Disclosed herein are compounds and methods for regulating transcription of a selected gene.

    摘要翻译: 公开了嵌合肽或融合蛋白,其包括RhoGAP活性结构域和至少一个靶向特异性Rho蛋白的特异性结构域。 融合蛋白可用于抑制细胞内的任何GTP酶活性。 融合蛋白对癌症的治疗特别有利。 本发明一般涉及能够调节GTP酶的嵌合肽,更具体地,涉及通过使用GTP酶活化蛋白靶向各种GTP酶的方法。 这些蛋白质可用于治疗癌症和其它与GTP酶有关的疾病。 本发明涉及核酸分子和编码的GTP酶活化蛋白及其变体,以及这些分子在表征,诊断,预防和治疗细胞信号传导,免疫和细胞增殖性疾病,特别是癌症中的用途。 本文公开了用于调节所选基因转录的化合物和方法。

    Methods for enhanced virus-mediated DNA transfer using molecules with virus-and cell-binding domains
    17.
    发明授权
    Methods for enhanced virus-mediated DNA transfer using molecules with virus-and cell-binding domains 失效
    使用具有病毒和细胞结合结构域的分子增强病毒介导的DNA转移的方法

    公开(公告)号:US06670177B2

    公开(公告)日:2003-12-30

    申请号:US09043981

    申请日:1998-06-19

    申请人: David A. Williams

    发明人: David A. Williams

    IPC分类号: C12N1500

    摘要: A method to increase the efficiency of transduction of hematopoietic and other cells by retroviruses includes infecting the cells in the presence of fibronectin or fibronectin fragments. The fibronectin and fibronectin fragments significantly enhance retroviral-mediated gene transfer into the cells, particularly hematopoietic cells including committed progenitors and primitive hematopoietic stem cells. The invention also provides improved methods for somatic gene therapy capitalizing on enhanced gene transfer, hematopoietic cellular populations, and novel constructs for enhancing retroviral-mediated DNA transfer into cells and their use.

    摘要翻译: 通过逆转录病毒增加造血细胞和其他细胞转导效率的方法包括在纤连蛋白或纤连蛋白片段存在下感染细胞。 纤连蛋白和纤连蛋白片段显着增强逆转录病毒介导的基因转移到细胞中,特别是造血细胞,包括确定的祖细胞和原始造血干细胞。 本发明还提供改进的体细胞基因治疗方法,利用增强的基因转移,造血细胞群体和用于增强逆转录病毒介导的DNA转移到细胞中的新构建体及其用途。

    Vehicle suspension system
    18.
    发明授权
    Vehicle suspension system 失效
    车辆悬挂系统

    公开(公告)号:US5590898A

    公开(公告)日:1997-01-07

    申请号:US531394

    申请日:1995-09-21

    摘要: A vehicle suspension device includes a plurality of hydraulic actuators which in use support the sprung mass of the vehicle relative to the wheel and hub assemblies of the vehicle. Each hydraulic actuator is part of a single vehicle suspension device which includes a signal processor device for processing signals corresponding to a plurality of variable perimeters of the vehicle's behavior and for producing a signal to control the extension and the contraction of the hydraulic actuator. A central processor communicates with all of the vehicle suspension devices and processes signals corresponding to a plurality of variable perimeters of the vehicle's behavior and produces control signals to control the extension and contraction of each actuator.

    摘要翻译: 车辆悬挂装置包括多个液压致动器,其在使用中相对于车辆的车轮和轮毂组件支撑车辆的悬挂质量。 每个液压致动器是单个车辆悬挂装置的一部分,其包括用于处理对应于车辆行为的多个可变周界的信号的信号处理器装置,并且用于产生用于控制液压致动器的延伸和收缩的信号。 中央处理器与所有车辆悬挂装置进行通信,并且处理对应于车辆行为的多个可变周界的信号,并且产生控制信号以控制每个致动器的伸缩。

    Logic cell using only two N type transistors for generating each logic
function
    19.
    发明授权
    Logic cell using only two N type transistors for generating each logic function 失效
    逻辑单元仅使用两个N型晶体管来产生每个逻辑功能

    公开(公告)号:US5418480A

    公开(公告)日:1995-05-23

    申请号:US68200

    申请日:1993-05-28

    IPC分类号: H03K19/173 H03K19/094

    CPC分类号: H03K19/1737

    摘要: A programmable logic cell has two inputs and six outputs, each output being a different logical function of the inputs. Each output is generated by a pair of NMOS transistors, one transistor of each pair having its gate connected to one of the inputs and the other transistor of each pair having its gate connected to the inverse of the same input.

    摘要翻译: 可编程逻辑单元具有两个输入和六个输出,每个输出是输入的不同逻辑功能。 每个输出由一对NMOS晶体管产生,每对的一个晶体管的栅极连接到一个输入,另一个晶体管的栅极连接到相同的输入的反相。

    Phonon controlled conductivity device
    20.
    发明授权
    Phonon controlled conductivity device 失效
    声子控制电导率仪

    公开(公告)号:US5324976A

    公开(公告)日:1994-06-28

    申请号:US964694

    申请日:1992-10-22

    申请人: David A. Williams

    发明人: David A. Williams

    CPC分类号: H01L49/00

    摘要: A controlled conductivity device utilizes incident phonons (1) to control conductivity. A body of material (2) is capable of changing its conductivity in response to the incident phonons by undergoing a metal-insulator transition.

    摘要翻译: 控制电导率器件利用入射声子(1)来控制电导率。 材料体(2)能够通过经历金属 - 绝缘体转变而响应于入射的声子而改变其导电性。