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131.
公开(公告)号:US4731394A
公开(公告)日:1988-03-15
申请号:US873566
申请日:1986-06-12
申请人: Werner Vogel , Guenther Heublein , Wolfram Hoeland , Manfred Boese , Karin Naumann , Gunter Carl , Juergen Vogel , Peter Wange , Jens Gummel , Peter Zinner , Eggert Beleites , Thomas Schubert
发明人: Werner Vogel , Guenther Heublein , Wolfram Hoeland , Manfred Boese , Karin Naumann , Gunter Carl , Juergen Vogel , Peter Wange , Jens Gummel , Peter Zinner , Eggert Beleites , Thomas Schubert
IPC分类号: A61L27/00 , A61K6/02 , A61L27/46 , C03C3/062 , C03C3/112 , C03C3/17 , C03C10/00 , C08K3/40 , C08K9/04 , C08K9/06
CPC分类号: A61L27/46 , A61K6/0061 , A61K6/0067 , A61K6/0094 , A61K6/0215 , A61K6/023 , A61K6/0235 , A61K6/0273
摘要: The invention relates to inorganic-organic compound substances useful for biomedical purposes. The object of the invention is to develop inorganic-organic compound materials which overcome the disadvantages of the state of art, wherein inorganic-organic compound substances for biomedical purposes possess to a large extent specifically adjustable characteristics. Inorganic initial substances form a new solid chemical compound with organic initial substances. The inorganic initial component consists of a biocompatible silicate glass and/or a silicate glass ceramic of the system SiO.sub.2 -Al.sub.2 O.sub.3 -MgO-Na.sub.2 O/K.sub.2 O-F.sup.-, and/or a bioactive phosphate silicate glass and/or a phosphate silicate glass ceramic of the system SiO.sub.2 -Al.sub.2 O.sub.3 -MgO-Na.sub.2 O/K.sub.2 O-CaO-P.sub.2 O.sub.5 F.sup.- and/or of the system SiO.sub.2 -MgO-K.sub.2 O-F.sup.- -CaO-P.sub.2 O.sub.5, and/or a bioactive phosphate glass and/or a phosphate glass ceramic of the system P.sub.2 O.sub.5 -Al.sub.2 O.sub.3 -CaO-Na.sub.2 O/K.sub.2 O, and/or a sintred ceramic based upon tricalcium phosphate and/or apatite. The organic initial component consists of a biocompatible, monomer-free, epoxidized polymeric hydrocarbon consisting only of the elements C, H, O having an average molecular weight Mn of 2,000 to 6,000 and an epoxy equivalence EEW of 50 to 500 g. The inorganic initial component is modified by phosphoric acid.
摘要翻译: 本发明涉及用于生物医学目的的无机 - 有机复合物质。 本发明的目的是开发克服现有技术缺点的无机 - 有机复合材料,其中用于生物医学目的的无机 - 有机复合物质在很大程度上具有特别可调的特性。 无机初始物质与有机初始物质形成新的固体化合物。 无机初始组分由系统SiO 2 -Al 2 O 3 -MgO-Na 2 O / K 2 O-F-的生物相容性硅酸盐玻璃和/或硅酸盐玻璃陶瓷和/或生物活性磷酸硅酸盐玻璃和/或磷酸硅酸盐玻璃陶瓷组成 系统SiO2-Al2O3-MgO-Na2O / K2O-CaO-P2O5F-和/或系统SiO2-MgO-K2O-F-CaO-P2O5和/或生物活性磷酸盐玻璃和/或磷酸盐玻璃陶瓷 系统P2O5-Al2O3-CaO-Na2O / K2O,和/或基于磷酸三钙和/或磷灰石的微量陶瓷。 有机起始组分由仅由元素C,H,O组成的生物相容性,无单体的环氧化聚合烃组成,其平均分子量& G为2,000至6,000,环氧当量EEW为50至500g。 无机初始成分被磷酸改性。
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公开(公告)号:US4594240A
公开(公告)日:1986-06-10
申请号:US530070
申请日:1983-09-07
CPC分类号: A61K9/0063 , A61K31/557 , A61K6/0061 , A61K6/0067
摘要: A sheet-shape adhesive preparation for promoting tooth-movement in orthodontics comprising a layer of a pharmaceutical composition containing as the active ingredient a prostaglandin (e.g. prostaglandin E.sub.1, prostaglandin E.sub.2, and prostaglandin F.sub.2.alpha.) in admixture with one or more high molecular weight compounds and a flexible base sheet, a process for the preparation thereof, and a method for promoting tooth-movement in orthodontics by applying the sheet-shape adhesive preparation to the mucous membrane of gingiva. Said preparation can be kept for a long period of time without being dissolved in saliva and without irritation or unpleasant feeling when applied to the mucous membrane of gingiva and hence can show the tooth-movement activity of the active prostaglandin for a long period of time.
摘要翻译: 一种用于促进口腔正畸的牙齿移动的片状粘合剂制剂,其包含与一种或多种高分子量化合物混合的含有作为活性成分的前列腺素(例如前列腺素E1,前列腺素E2和前列腺素F2α)的药物组合物层 和柔性基片,其制备方法以及通过将片状粘合剂施用于牙龈粘膜来促进正畸矫正中的牙齿移动的方法。 所述制剂可以长时间保存而不会溶解在唾液中,并且当施用到牙龈粘膜时没有刺激或不愉快的感觉,因此可以长时间显示活性前列腺素的牙齿运动活性。
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公开(公告)号:US4363794A
公开(公告)日:1982-12-14
申请号:US949031
申请日:1978-10-06
IPC分类号: A61K6/00 , A61K6/02 , A61K8/19 , A61K8/20 , A61K8/21 , A61K8/36 , A61K8/362 , A61K8/365 , A61K8/67 , A61K31/19 , A61K33/16 , A61K33/24 , A61Q11/00 , C02F5/08 , A61K7/18 , A61K7/16 , A61K33/42
摘要: An oral composition is disclosed which comprises a stannous salt such as stannous fluoride, a water-soluble fluoride salt such as sodium fluoride and an orally acceptable acid such as L-ascorbic acid, lactic acid, malonic acid, tartaric acid, citric acid, hydrochloric acid and pyrophosphoric acid, the molar ratio of fluoride ion to stannous ion being in the range of 3.2 to 7:1, preferably 3.5-6:1, in an aqueous condition and the pH of the composition being in the range of from 2 to 4. The composition exhibits excellent effects on the inhibition of dental caries.
摘要翻译: 公开了一种口服组合物,其包含亚锡盐如氟化亚锡,水溶性氟化物盐如氟化钠和口服可接受的酸如L-抗坏血酸,乳酸,丙二酸,酒石酸,柠檬酸,盐酸 酸和焦磷酸,氟化物离子与亚锡离子的摩尔比在水溶液条件下在3.2至7:1的范围内,优选3.5-6:1,组合物的pH在2至 该组合物对抑制龋齿表现出极好的效果。
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公开(公告)号:US3913229A
公开(公告)日:1975-10-21
申请号:US44567874
申请日:1974-02-25
申请人: MITER INC
CPC分类号: A61K6/033 , A61K6/0035 , A61K6/0038 , A61K6/0041 , A61K6/0067 , A61K6/05 , A61K6/0675 , C08L23/20 , C08L7/00
摘要: Dental methods and materials are disclosed for treating diseased or traumatized teeth and peridontal tissues. Physiologically compatible and soluble calcium phosphate compounds are prepared into a porous aggregate paste or powder and positioned adjacent to calcified tissue in contact with a blood supply. Such a technique permits improved methods for pulp capping procedures, root canal procedures, tooth replanting procedures and for corrective peridontal procedures.
摘要翻译: 公开了用于治疗患病或创伤的牙齿和牙周组织的牙科方法和材料。 将生理相容和可溶性磷酸钙化合物制备成多孔骨料糊或粉末,并定位在与血液供应接触的钙化组织附近。 这种技术允许用于纸浆封盖程序,根管程序,牙齿重新植入程序和矫正性牙周手术的改进方法。
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公开(公告)号:US3772432A
公开(公告)日:1973-11-13
申请号:US3772432D
申请日:1971-01-11
申请人: LESCARDEN LTD
发明人: BALASSA L
CPC分类号: A61K9/14 , A61K6/0067 , A61K6/0017 , C08L89/04 , C08L89/06 , C08L89/005 , C08L89/00 , C08L1/10 , C08L1/26 , C08L3/02
摘要: CARTILAGE POWDER IS DESCRIBED HEREIN FOR USE IN DENTAL APPLICATIONS INCLUDING THE TREATMENT AND PREVENTION OF DRY SOCKETS, GINGIVAL TISSUES AND MANDIBULAR CYSTECTOMIES, THE CARTILAGE POWDER BEING USED IN THE FORM OF A PASTE OF LOW MOBILITY.
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公开(公告)号:US3029188A
公开(公告)日:1962-04-10
申请号:US71628458
申请日:1958-02-20
申请人: OLIN MATHIESON
发明人: CYR GILMAN N , BERNSTEIN HARRIS B
CPC分类号: A61K9/006 , A61K6/0067 , A61K6/0026 , C08L89/06 , C08L39/06 , C08L5/06 , C08L1/286 , C08L5/04
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公开(公告)号:US2846322A
公开(公告)日:1958-08-05
申请号:US28509252
申请日:1952-04-29
申请人: EDGAR SCHAEFER
IPC分类号: A61K6/02
CPC分类号: A61K6/0067 , A61K6/0612 , A61K6/0643
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公开(公告)号:US2665218A
公开(公告)日:1954-01-05
申请号:US1462948
申请日:1948-03-12
申请人: SAFFIR JACOB A
发明人: SAFFIR JACOB A
CPC分类号: A61K6/0067 , A61K6/0612 , A61K6/0643
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公开(公告)号:US1900237A
公开(公告)日:1933-03-07
申请号:US38026329
申请日:1929-07-22
申请人: HARSHMAN VERN S
发明人: HARSHMAN VERN S
IPC分类号: A61K6/097
CPC分类号: A61K6/0067 , A61K6/0005 , A61K6/0058 , A61K6/0675 , A61K6/097 , C08L1/18
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公开(公告)号:US1642653A
公开(公告)日:1927-09-13
申请号:US8949526
申请日:1926-02-19
申请人: GOLDSTEIN ALFRED D
发明人: GOLDSTEIN ALFRED D
IPC分类号: A61K6/02
CPC分类号: A61K6/0067 , A61K6/0017 , C08L89/06 , C08L5/12
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