COMPOSITION INCLUDING RAPAMYCIN AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING HEARING LOSS
    131.
    发明申请
    COMPOSITION INCLUDING RAPAMYCIN AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING HEARING LOSS 有权
    包括RAPAMYCIN作为主动成分的组合物,用于预防或治疗听力损失

    公开(公告)号:US20160101088A1

    公开(公告)日:2016-04-14

    申请号:US14876826

    申请日:2015-10-07

    CPC classification number: A61K31/436 A23L33/10 A61K31/7036

    Abstract: A pharmaceutical or health food includes rapamycin as an active ingredient, the pharmaceutical or health food being applied for prevention, improvement, and treatment of ototoxic hearing loss caused by an aminoglycoside-based antibiotic, sudden sensorineural hearing loss, and noise induced hearing loss. The pharmaceutical or health food is also applied to a pharmaceutical composite preparation of an aminoglycoside-based antibiotic and rapamycin, the pharmaceutical composite preparation reducing a side effect of the aminoglycoside-based antibiotic.

    Abstract translation: 药物或保健食品包括雷帕霉素作为活性成分,用于预防,改善和治疗由氨基糖苷类抗生素引起的耳毒性听力损失,突发性感觉神经性听力损失和噪声引起的听力损失的药物或保健食品。 药物或保健食品也适用于基于氨基糖苷类的抗生素和雷帕霉素的药物复合制剂,该药物复合制剂减少了基于氨基糖苷类的抗生素的副作用。

    Composition for Treating or Preventing Diseases Caused by Vascular Permeability, Containing Imatinib or Pharmaceutically Acceptable Salt Thereof as Active Ingredient
    132.
    发明申请
    Composition for Treating or Preventing Diseases Caused by Vascular Permeability, Containing Imatinib or Pharmaceutically Acceptable Salt Thereof as Active Ingredient 有权
    用于治疗或预防血管通透性引起的疾病的组合物,含有伊马替尼或其药学上可接受的盐作为活性成分

    公开(公告)号:US20150320750A1

    公开(公告)日:2015-11-12

    申请号:US14409441

    申请日:2013-06-10

    CPC classification number: A61K31/506 C07D401/04

    Abstract: The present invention relates to a pharmaceutical composition for treating or preventing diseases caused by vascular permeability, containing imatinib, which has been conventionally used as an agent for treating chronic myeloid leukemia, or a pharmaceutically acceptable salt thereof as an active ingredient, and a method for treating disease caused by vascular permeability using the composition. The pharmaceutical composition for treating or preventing diseases caused by vascular permeability of the present invention contains imatinib, which has been conventionally used as an agent for treating chronic myeloid leukemia, as an active ingredient, so as to provide a novel use of imatinib and to be able to effectively treat or prevent diseases caused by vascular permeability, and thus may be widely applied to develop a novel agent for treating diseases caused by vascular permeability.

    Abstract translation: 本发明涉及用于治疗或预防由血管通透性引起的疾病的药物组合物,其含有伊马替尼,其通常用作治疗慢性骨髓性白血病的药物或其药学上可接受的盐作为活性成分, 使用该组合物治疗由血管通透性引起的疾病。 用于治疗或预防由本发明的血管渗透性引起的疾病的药物组合物含有作为常规用作治疗慢性骨髓性白血病的药物的伊马替尼作为活性成分,以提供伊马替尼的新用途,并且为 能够有效地治疗或预防由血管通透性引起的疾病,因此可广泛应用于开发用于治疗由血管渗透性引起的疾病的新型药剂。

    METHOD AND APPARATUS FOR DECODING LOW-DENSITY PARITY-CHECK CODE
    133.
    发明申请
    METHOD AND APPARATUS FOR DECODING LOW-DENSITY PARITY-CHECK CODE 有权
    用于解密低密度奇偶校验码的方法和装置

    公开(公告)号:US20150303944A1

    公开(公告)日:2015-10-22

    申请号:US14537571

    申请日:2014-11-10

    CPC classification number: H03M13/1131 H03M13/1117 H03M13/6502

    Abstract: Provided is a method of decoding a low-density parity-check code (LDPC). The decoding method including an initialization process, a check node update process, a variable node update process, a tentative decoding process, and a parity check process, for a plurality of check nodes and a plurality of variable nodes, further includes detecting at least one inactive variable nodes that do not require variable node update among the variable nodes, the variable node update process is performed only on active variable nodes except for the inactive variable node, and the check node update process is performed without using the inactive variable node.

    Abstract translation: 提供了一种对低密度奇偶校验码(LDPC)进行解码的方法。 对于多个校验节点和多个可变节点,包括初始化处理,校验节点更新处理,变量节点更新处理,暂定解码处理和奇偶校验处理的解码方法还包括检测至少一个 在变量节点之间不需要变量节点更新的非活动变量节点,仅在非活动变量节点之外的活动变量节点上执行变量节点更新过程,并且不使用非活动变量节点执行校验节点更新过程。

    METHOD AND APPARATUS FOR PREDICTING MOBILITY BASED ON RELATIVE MOBILE CHARACTERISTICS
    136.
    发明申请
    METHOD AND APPARATUS FOR PREDICTING MOBILITY BASED ON RELATIVE MOBILE CHARACTERISTICS 有权
    基于相对移动特征预测移动性的方法和装置

    公开(公告)号:US20150195806A1

    公开(公告)日:2015-07-09

    申请号:US14588682

    申请日:2015-01-02

    CPC classification number: H04W4/023 G01S5/0289 G01S5/0294 G06N7/005 H04W4/029

    Abstract: An apparatus and method for predicting mobility based on relative mobile characteristics are disclosed herein. The method of predicting mobility based on relative mobile characteristics includes detecting, by each of a plurality of sensor nodes of a sensor network including the plurality of sensor nodes, a change in relative location with respect to an observed node; recording, by the each of the plurality of sensor nodes, information about the detected change in relative location; generating, by the each of the plurality of sensor nodes, a mathematical model for a possibility of approach of the observed node with respect to the each of the plurality of sensor nodes using the recorded relative location change information; and predicting probabilistically, by the each of the plurality of sensor nodes, whether the observed node will approach the each of the plurality of sensor nodes using the mathematical model.

    Abstract translation: 本文公开了一种用于基于相对移动特性来预测移动性的装置和方法。 基于相对移动特性预测移动性的方法包括通过包括多个传感器节点的传感器网络的多个传感器节点中的每一个相对于观察到的节点来检测相对位置的变化; 通过所述多个传感器节点中的每一个记录关于检测到的相对位置的变化的信息; 通过所述多个传感器节点中的每一个,使用所记录的相对位置变化信息,生成所述观测节点相对于所述多个传感器节点中的每一者接近的可能性的数学模型; 并且通过所述多个传感器节点中的每个传感器节点概率地预测所观察的节点是否将使用所述数学模型接近所述多个传感器节点中的每一个。

    COMPOSITION COMPRISING MATERIAL FOR INHIBITING SCF OR RECEPTOR THEREOF FOR TREATING OR PREVENTING DISEASES ASSOCIATED WITH VASCULAR PERMEABILITY
    137.
    发明申请
    COMPOSITION COMPRISING MATERIAL FOR INHIBITING SCF OR RECEPTOR THEREOF FOR TREATING OR PREVENTING DISEASES ASSOCIATED WITH VASCULAR PERMEABILITY 有权
    包含用于抑制SCF或受体的材料的组合物用于治疗或预防与血管渗透性相关的疾病

    公开(公告)号:US20150191729A1

    公开(公告)日:2015-07-09

    申请号:US14398531

    申请日:2012-10-25

    Abstract: The present invention relates to a composition comprising a material for inhibiting stem cell factor (SCF) or the receptor thereof for treating or preventing vascular permeability related diseases. Also, the present invention relates to a method for screening for an agent for treating vascular permeability related diseases, comprising the steps of: (a) treating a sample from a patient suspected of having a disease associated with vascular permeability with a candidate material; and (b) comparing the level of expression of the SCF or the receptor thereof with that of a control group. The present invention verifies SCF as a novel target for regulating vascular permeability. When the present invention is used, vascular permeability is decreased in diseases of the eye involving increased vascular permeability, thereby effectively treating or preventing vascular permeability related diseases. Also, vascular permeability can be effectively regulated using the composition. Further, the present invention can be provided as an effective means for screening an agent for treating vascular permeability related diseases by measuring the regulation of the expressions of SCF and c-Kit.

    Abstract translation: 本发明涉及包含用于抑制干细胞因子(SCF)的材料或其受体用于治疗或预防血管通透性相关疾病的组合物的组合物。 此外,本发明涉及一种筛选用于治疗血管通透性相关疾病的药剂的方法,包括以下步骤:(a)用怀疑患有与血管通透性相关的疾病的患者用候选物质处理样品; 和(b)比较SCF或其受体的表达水平与对照组的表达水平。 本发明将SCF验证为调节血管通透性的新靶标。 当使用本发明时,涉及血管通透性增加的眼睛疾病中的血管通透性降低,从而有效地治疗或预防血管通透性相关疾病。 此外,可以使用组合物有效调节血管通透性。 此外,通过测量SCF和c-Kit的表达的调节,本发明可以作为筛选用于治疗血管通透性相关疾病的药剂的有效手段。

    COATING METHOD USING PARTICLE ALIGNMENT AND PARTICLE COATED SUBSTRATE MANUFACTURED THEREBY
    138.
    发明申请
    COATING METHOD USING PARTICLE ALIGNMENT AND PARTICLE COATED SUBSTRATE MANUFACTURED THEREBY 有权
    使用颗粒对准的涂布方法和制造的颗粒涂层基材

    公开(公告)号:US20150165476A1

    公开(公告)日:2015-06-18

    申请号:US14372118

    申请日:2013-11-27

    Abstract: Disclosed is a coating method using particle alignment, including preparing a cohesive polymer substrate having a smooth surface; and coating the smooth surface of the cohesive polymer substrate with a plurality of particles while forming recesses respectively corresponding to the particles on the smooth surface of the cohesive polymer substrate by pressing the particles to the cohesive polymer substrate, so that binding properties between the particles and the cohesive polymer substrate are enhanced.

    Abstract translation: 公开了一种使用粒子排列的涂布方法,包括制备具有光滑表面的内聚聚合物基材; 并且用多个颗粒涂覆粘合聚合物基材的光滑表面,同时通过将颗粒压到粘合性聚合物基材上,形成分别对应于粘合聚合物基材的光滑表面上的颗粒的凹槽,从而使颗粒和 增强了内聚合物基材。

    COMPOSITION FOR DIAGNOSIS OF BEHCET'S DISEASE
    139.
    发明申请
    COMPOSITION FOR DIAGNOSIS OF BEHCET'S DISEASE 审中-公开
    BEHCET疾病诊断组合物

    公开(公告)号:US20150153340A1

    公开(公告)日:2015-06-04

    申请号:US14310851

    申请日:2014-06-20

    Inventor: Seong Hyang SOHN

    CPC classification number: G01N33/56966 G01N2333/70596

    Abstract: The present invention relates to a composition for the diagnosis of Behcet's disease, comprising an agent for measuring the expression level of macrophage mannose receptor 1 (CD206), a kit for the diagnosis of Behcet's disease, and an information providing method using the same. According to the present invention, it is possible to diagnose the pathogenesis of Behcet's disease without being affected by symptoms of Behcet's disease or prescription drugs and differentially diagnose between active Behcet's disease and inactive Behcet's disease.

    Abstract translation: 本发明涉及一种用于诊断白塞病的组合物,其包含用于测量巨噬细胞甘露糖受体1(CD206)的表达水平的试剂,用于诊断白塞病的试剂盒和使用该试剂盒的信息提供方法。 根据本发明,可以诊断白塞氏病的发病机制,而不受白塞病或处方药的症状影响,并且在活动的白塞病和不活动的贝切特病之间进行差异诊断。

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