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公开(公告)号：US20190241663A1
公开(公告)日：2019-08-08
申请号：US16167000
申请日：2018-10-22
Applicant: Genentech, Inc.
Inventor： Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K47/68 , C07K16/30 , A61K51/10 , G01N33/569 , A61K39/395 , A61K38/08 , A61K47/65
CPC classification number: C07K16/2827 , A61K38/08 , A61K39/39558 , A61K47/65 , A61K47/6801 , A61K47/6809 , A61K47/6849 , A61K47/6855 , A61K51/1027 , A61K51/1051 , A61K2039/505 , C07K16/3015 , C07K2317/24 , C07K2317/33 , C07K2317/56 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/56972
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号：US20190177432A1
公开(公告)日：2019-06-13
申请号：US16284774
申请日：2019-02-25
Applicant: GENENTECH, INC.
Inventor： Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号：US20190010228A1
公开(公告)日：2019-01-10
申请号：US16018458
申请日：2018-06-26
Applicant: Genentech, Inc.
Inventor： Yan Wu , Weilan Ye , Jeremy Bryant Burton , Cecilia Chiu
Abstract: The invention provides anti-LRP5 antibodies and methods of making and using the same.
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公开(公告)号：US10005848B2
公开(公告)日：2018-06-26
申请号：US14725412
申请日：2015-05-29
Applicant: Genentech, Inc.
Inventor： Jackson G Egen , Jo-Anne Hongo , Steven Kauder , Robert A Lazarus , Lydia Santell , Yan Wu , Meredith Hazen , Wei-Ching Liang
IPC: C07K16/40 , C07K14/705 , C07K16/28 , C07K14/52 , C12Q1/68 , G01N33/74 , C12Q1/6883 , A61K39/00
CPC classification number: C07K16/40 , A61K2039/505 , C07K14/52 , C07K14/70596 , C07K16/2863 , C07K2317/55 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/30 , C12Q1/6883 , C12Q2600/106 , C12Q2600/156 , G01N33/74 , G01N2333/71 , G01N2333/912 , G01N2800/065 , G01N2800/20 , G01N2800/52
Abstract: This invention relates to RON compositions, in particular RON composition comprising a RON agonist, and methods of using the compositions for the treatment of diseases. The invention also relates to diagnosis of RON-associated or MSP-associated diseases.
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公开(公告)号：US10000571B2
公开(公告)日：2018-06-19
申请号：US15266105
申请日：2016-09-15
Applicant: Genentech, Inc.
Inventor： Avi Ashkenazi , Jing Qing , Christian Wiesmann , Yan Wu
IPC: C07K16/28 , A61K39/395 , C07K16/30 , A61K39/00
CPC classification number: C07K16/2863 , A61K39/395 , A61K39/3955 , A61K39/39558 , A61K2039/505 , C07K16/3038 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30
Abstract: The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies.
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Patent Agency Ranking
公开(公告)号：US20180112005A1
公开(公告)日：2018-04-26
申请号：US15722635
申请日：2017-10-02
Applicant: Genentech, Inc.
Inventor： Christian W. Siebel , Yan Wu
CPC classification number: C07K16/30 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K14/705 , C07K14/71 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K16/3015 , C07K2317/14 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C12N5/10 , C12N5/12 , C12N15/09 , C12N15/63 , C12N2330/50
Abstract: The invention provides anti-Notch1 NRR antibodies, and compositions comprising and methods of using these antibodies.
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公开(公告)号：US20180044420A1
公开(公告)日：2018-02-15
申请号：US15657471
申请日：2017-07-24
Applicant: Genentech, Inc.
Inventor： Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: C07K16/28 , A61K47/68 , A61K51/10 , A61K31/706 , G01N33/574 , C07K16/30 , A61K31/5517
CPC classification number: C07K16/2851 , A61K31/5517 , A61K31/706 , A61K47/68 , A61K47/6817 , A61K47/6867 , A61K47/6889 , A61K51/1069 , A61K51/1093 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/57426 , G01N2333/7056
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号：US09518121B2
公开(公告)日：2016-12-13
申请号：US14619930
申请日：2015-02-11
Applicant: Genentech, Inc.
Inventor： Yvonne Chinn , Julie Q. Hang , Christian W. Siebel , Yan Wu
IPC: A61K39/395 , C07K16/28 , A61K47/48 , A61K39/00
CPC classification number: C07K16/2896 , A61K39/3955 , A61K47/6849 , A61K2039/505 , A61K2039/507 , C07K16/28 , C07K2317/21 , C07K2317/33 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The invention provides anti-Jagged1 antibodies and methods of using the same.
Abstract translation: 本发明提供了抗Jagged1抗体及其使用方法。
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公开(公告)号：US20160185855A1
公开(公告)日：2016-06-30
申请号：US14879702
申请日：2015-10-09
Applicant: GENENTECH INC.
Inventor： Yan Wu , Weilan Ye , Jeremy Bryant Burton , Cecilia Chiu
IPC: C07K16/28
CPC classification number: C07K16/28 , A61K39/395 , A61K47/6849 , A61K2039/505 , A61P9/10 , A61P27/02 , C07H21/04 , C07K2317/21 , C07K2317/24 , C07K2317/56 , C07K2317/567 , C07K2317/75 , C07K2317/92
Abstract: The invention provides anti-LRP5 antibodies and methods of making and using the same.
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公开(公告)号：US20160102146A1
公开(公告)日：2016-04-14
申请号：US14856731
申请日：2015-09-17
Applicant: GENENTECH, INC.
Inventor： Jo-Anne Hongo , Weiguang Mao , Paul Polakis , Andrew Polson , Rajesh Vij , Yan Wu , Wei-Ching Liang
IPC: C07K16/28
CPC classification number: C07K16/28 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6849 , A61K47/6859 , A61K47/6863 , A61K2039/505 , C07K16/30 , C07K16/3046 , C07K2317/24 , C07K2317/33 , C07K2317/73 , C07K2317/92 , G01N33/6893
Abstract: The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same.
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