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公开(公告)号：US10454691B2
公开(公告)日：2019-10-22
申请号：US15604376
申请日：2017-05-24
Inventor： Bertrand Francis Cambou
Abstract: Systems and methods for providing variable access authentication respond to the need of a hierarchical level of security, which may include the use of multiple physically unclonable functions (PUFs) and/or the distribution of a set of authentication keys with “don't care” states. Each of the multiple PUFs can drive a separate level of access control, while “don't care” states can be included in the authentication keys when the security risk levels are lower. These two methods can be implemented independently, or in a combination for higher levels of security. At one end of the embodiment the IT manager can have backdoor capabilities if a user forgot a password, on the other end access control to an Internet device needs to be extremely stringent when the user operates in unsafe territory.
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公开(公告)号：US20190163897A1
公开(公告)日：2019-05-30
申请号：US16201861
申请日：2018-11-27
Inventor： Bertrand Francis Cambou
CPC classification number: H04L9/3278 , G06F21/44 , G06F21/46 , G06F2221/2103 , H04L9/0643 , H04L9/0866 , H04L9/0869 , H04L9/3226
Abstract: The present invention provides a method for authenticating distributed peripherals on a computer network using an array of physically unclonable functions (PUF). As each PUF is unique, each PUF is able to generate a plurality of challenge response pairs that are unique to that PUF. The integrated circuits of the PUF comprise a plurality of cells, where a parameter (such as a voltage) of each cell may be measured (possibly averaged over many readings). The plurality of cells in the PUF may be arranged in a one, two or more dimensional matrix. A protocol based on an addressable PUF generator (APG) allows the protection of a network having distributed peripherals such as Internet of things (IoT), smart phones, lap top and desk top computers, or ID cards. This protection does not require the storage of a database of passwords, or secret keys. and thereby is immune to traditional database hacking attacks.
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公开(公告)号：US20190151405A1
公开(公告)日：2019-05-23
申请号：US16250612
申请日：2019-01-17
Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE , ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
Inventor： David Engelthaler , Elizabeth Driebe , Hongwei "Holly" Yin , Michael Valentine , Donald Chow , Jolene Bowers , Paul Keim , Bridget Barker
IPC: A61K38/13 , A61K31/495 , A61K45/06 , A61K31/4196 , A61K31/7135 , A61K31/5415 , A61K31/5377 , A61K31/58 , A61K31/609 , A61K31/4741 , A61K31/428 , A61K31/4174 , A61K31/404 , A61K31/353 , A61K31/277 , A61K31/138 , A61K31/496
Abstract: The present invention comprises methods of treating an infection using a pharmaceutical composition comprising an active ingredient selected from Table 1. In some aspects, the infection can be caused by one or more pathogens, including fungal pathogens. For example, the infection may b
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公开(公告)号：US20190078141A1
公开(公告)日：2019-03-14
申请号：US16083860
申请日：2017-03-14
Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE , ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
Inventor： Jolene Bowers , Elizabeth Driebe , David Engelthaler , Paul Keim , Darrin Lemmer
IPC: C12Q1/689 , C12Q1/6853 , C12Q1/686 , C12Q1/6827
Abstract: The present invention provides a method of detecting one or more Klebsiella species within a sample from a subject, the method comprising: subjecting DNA and/or RNA from the sample to a PCR amplification reaction using primer pairs targeting species-specific canonical single nucleotide polymorphisms (canSNPs); and analyzing amplification products resulting from the PCR amplification reaction to detect the one or more Klebsiella species. The present invention also provides a kit for detection of one or more Klebsiella species, Klebsiella clonal groups, AMR genes, and/or virulence genes, the kit comprising primer pairs targeting species-specific canSNPs, K. pneumoniae genes M1 and M2, clonal group-specific canSNPs, AMR genes, and/or virulence genes.
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公开(公告)号：US10147558B2
公开(公告)日：2018-12-04
申请号：US15472119
申请日：2017-03-28
Inventor： Constantin Ciocanel , Cindy Browder , Bertrand Francis Cambou
Abstract: A composition of a capacitor and a method to form same are disclosed. The capacitor comprises a first electrode, a second electrode, and at least one cellular material disposed between said first electrode and said second electrode. Further, the capacitor is at least partially impregnated with one or more liquid prepolymers comprising an electrolyte material, which is cured to form a polymeric matrix.
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Patent Agency Ranking
公开(公告)号：US20180343130A1
公开(公告)日：2018-11-29
申请号：US16036498
申请日：2018-07-16
Inventor： Bertrand Cambou
CPC classification number: H04L9/3278 , H04L9/006 , H04L9/0643 , H04L9/0662 , H04L9/3226 , H04L63/083
Abstract: The present invention provides a method for authenticating distributed peripherals on a computer network using an array of physically unclonable functions (PUF). As each PUF is unique, each PUF is able to generate a plurality of challenge response pairs that are unique to that PUF. The integrated circuits of the PUF comprise a plurality of cells, where a parameter (such as a voltage) of each cell may be measured (possibly averaged over many readings). The plurality of cells in the PUF may be arranged in a one, two or more dimensional matrix. A protocol based on an addressable PUF generator (APG) allows the protection of a network having distributed peripherals such as Internet of things (IoT), smart phones, lap top and desk top computers, or ID cards. This protection does not require the storage of a database of passwords, or secret keys, and thereby is immune to traditional database hacking attacks.
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公开(公告)号：US09994917B2
公开(公告)日：2018-06-12
申请号：US14819529
申请日：2015-08-06
Applicant: THE TRANSLATION GENOMICS RESEARCH INSTITUTE , ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
Inventor： David Engelthaler , Elizabeth Driebe , Erin Kelley , Paul Keim
CPC classification number: C12Q1/689 , C12Q2600/156 , C12Q2600/158 , C12Q2600/16
Abstract: Embodiments of the invention provide a method of genotyping a C. gattii sample, which can include forming a plurality of mixtures for nucleic amplification. The method can include amplification of specific sequences within the C. gattii genome that can provide definitive genotype information to distinguish between one or more types or subtypes of C. gattii.
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公开(公告)号：US20170235938A1
公开(公告)日：2017-08-17
申请号：US15434976
申请日：2017-02-16
Inventor： Bertrand Cambou , Abolfazl Razi
CPC classification number: G06F21/36 , G06Q20/40 , G06Q20/42 , H04L9/3278 , H04L63/08 , H04L63/1466
Abstract: An authentication system for a computing environment uses physically unclonable functions (PUFs) to authenticate requests to perform an action in the environment. The system receives, from an imaging device, an image of a physically unclonable object associated with the electronic request. The system then obtains from a computer server operating within the system via an encrypted communication channel, a challenge associated with the object. The system uses extraction parameters encoded within the challenge to transform a portion of the image and produce authentication data representing a response to the challenge. The system extracts, using the extraction parameters, the authentication data from the image and determines whether the challenge and response match and the request is authenticated.
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109.发明申请SYSTEMS AND METHODS FOR UNIVERSAL TAIL-BASED INDEXING STRATEGIES FOR AMPLICON SEQUENCING 审中-公开用于AMPLICON序列的通用基于尾段的指数策略的系统和方法公开(公告)号：US20160326572A1
公开(公告)日：2016-11-10
申请号：US15034544
申请日：2014-11-10
Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE , ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
Inventor： James M. Schupp , Rebecca E. Colman , David Engelthaler , John Gillece , Nathan Hicks , Paul S. Keim
IPC: C12Q1/68
CPC classification number: C12Q1/686 , C12Q1/6869 , C12Q1/6874 , C12Q2525/155 , C12Q2525/191 , C12Q2537/143
Abstract: Some embodiments of the invention include a method of preparing a sample for sequencing that includes receiving a sample and amplifying at least one marker within the sample. In some embodiments, amplification of the first marker may include mixing the sample with a first oligonucleotide that comprises a first universal tail sequence and a second oligonucleotide that comprises a second universal tail sequence. In some aspects of the invention, the first universal tail sequence and the second universal tail sequence are different sequences.
Abstract translation: 本发明的一些实施方案包括制备用于测序的样品的方法，其包括接收样品并扩增样品中的至少一个标记物。 在一些实施方案中，第一标记的扩增可以包括将样品与包含第一通用尾部序列的第一寡核苷酸和包含第二通用尾部序列的第二寡核苷酸混合。 在本发明的一些方面，第一通用尾部序列和第二通用尾部序列是不同的序列。
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公开(公告)号：US20250023736A1
公开(公告)日：2025-01-16
申请号：US18638593
申请日：2024-04-17
Inventor： Bertrand F CAMBOU
Abstract: Methods for the storage and retrieval of a digital file are disclosed. The file is encrypted with a random binary key. A mathematical CRP mechanism is used to generate an ordered list of responses from a list of challenges. A subset of responses within the ordered list of responses is selected, which each selected response occupying a position in the ordered list that is the same position as a first binary symbol in the random key. In this way, the key can be encoded in the selection of responses. To recover the key, the selected responses are compared to a full list of responses to determine which of the responses in the full list match selected responses. Matches indicate the first binary symbol in the corresponding position in the key and non-matches indicate the second binary symbol. In this way, the key is reconstructed, and file may be decrypted.
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