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公开(公告)号：US12107973B1
公开(公告)日：2024-10-01
申请号：US17523551
申请日：2021-11-10
发明人： Bertrand F Cambou , Michael Gowanlock , Bahattin Yildiz , Dina Ghanaimiandoab , Kaitlyn Lee , Stefan W Nelson , Christopher Philabaum , Alyssa J Stenberg , Jordan A Wright
CPC分类号： H04L9/3278 , H04L9/0825 , H04L9/0861 , H04L9/3093 , H04L9/3263
摘要： Systems and methods of improving public key infrastructure using PUF arrays are disclosed. The systems and methods are usable to improve PKI based on Lattice and Code cryptography. In the disclosed system, a client device includes an enrolled PUF array, and a server device acting as a Certification Authority includes an image of the PUF array including previously measured responses data for the devices in the PUF array. The CA sends a set of addresses to the client device, which generates a public key from measuring the response of PUF devices with the addresses. The CA receives the generated public key, and determines that the enrolled PUF was used to generate the key.
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2.发明公开公开(公告)号：US20230390094A1
公开(公告)日：2023-12-07
申请号：US18233236
申请日：2023-08-11
IPC分类号： A61F5/01
CPC分类号： A61F5/0127 , A61F2005/0155 , A61F2005/0167 , A61F2005/0179
摘要： An assistive ankle foot orthosis is described. The AFO has a vertical shank member arranged laterally to a user's limb. The member carries a rotational bearing and a rotational element such as a pulley. The rotational bearing is lateral to a user's ankle. The pulley is connected to a footplate. The footplate can be actuated to provide joint movement assistance or resistance to the user upon rotation of the pulley. The AFO includes an ankle angle and angular velocity sensor and a pressure sensor located under the user's forefoot. The AFO includes a controller that computes an estimate of the user's peak joint power on the basis of a series of products of measurements of foot pressure and angular velocity.
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公开(公告)号：US20230295743A1
公开(公告)日：2023-09-21
申请号：US18165310
申请日：2023-02-06
申请人： THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE , ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY , CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC)
发明人： Elizabeth Driebe , Jolene Bowers , David Engelthaler , Paul Keim , Brandi Limbago , James K. Rasheed , Linda McDougal , Valerie S. Albrecht
CPC分类号： C12Q1/689 , C12Q1/686 , C12Q2531/113 , C12Q2561/113 , A61K31/505
摘要： The present invention provides a method of detecting Staphylococcus aureus in a subject, by contacting a sample obtained from the subject with at least one detectably labeled probe of the invention or detecting in the sample identity to a sequence of the invention. The invention is also directed to kits, microarrays and detectable Staphylococcus aureus polynucleotide probes useful in detecting the presence of Staphylococcus aureus.
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4.发明公开公开(公告)号：US20230163980A1
公开(公告)日：2023-05-25
申请号：US17991706
申请日：2022-11-21
CPC分类号： H04L9/3278 , H04L63/0428 , H04L9/0869
摘要： Methods and systems for managing access to encrypted digital files are proposed. A remote or client device including an array of physical unclonable function (PUF) devices is provided. A server device has an image of the PUF, with previously measured responses. The server device randomly selects a set of responses from a first list PUF devices in its image. The server device then generates masking data to select among the first list to generate response bitstream. The response bitstream is used to encrypt a file, which sent to the client for storage. The random number is also sent. Later, the server generates an encrypted message digest from which the client can retrieve the masking data, which is used with the random number to generate a response bitstream from the client PUF to decrypt the file.
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公开(公告)号：US20230055519A1
公开(公告)日：2023-02-23
申请号：US17793383
申请日：2021-01-16
申请人： THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE , ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
发明人： Paul Keim , Erik Settles , Jason Ladner , John Altin , Charles Hall Davis Williamson, IV , Sunil Sharma
IPC分类号： C40B30/04 , C12N15/10 , C12Q1/6809 , C12N15/62
摘要： The present invention provides methods of maturing a peptide library and of identifying peptides having increased specific binding to a target molecule and/or differential specific binding to target molecules. The present invention also provide methods of developing diagnostic assays, detection kits and therapeutic agents with the peptides.
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公开(公告)号：US20230038135A1
公开(公告)日：2023-02-09
申请号：US17871850
申请日：2022-07-22
摘要： Systems and methods for cryptographic key generation at a client and server are disclosed. The client has an array of PUF devices, and the server has an image that PUF. The server sends the client addresses of PUF devices to be measured, and retrieves previously stored responses corresponding to those addresses from its database. The client measures responses at the addresses. Each device hashes the resulting responses, and the server compares the hash received from the client to its own. If the hashes to not match, the server searches for a matching hash be perturbing the measured response bit stream until a match is achieved. The perturbed response bitstream, and the measured response at the client are then salted, and used for key generation.
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公开(公告)号：US11572591B2
公开(公告)日：2023-02-07
申请号：US16607716
申请日：2018-04-26
申请人： THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE , ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY , CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC)
发明人： Elizabeth Driebe , Jolene Bowers , David Engelthaler , Paul Keim , Brandi Limbago , James K. Rasheed , Linda McDougal , Valerie S. Albrecht
IPC分类号： C12Q1/689 , C12Q1/686 , A61K31/505 , A61K31/635 , A61K38/14 , A61K31/65 , A61K31/5377 , A61K31/496
摘要： The present invention provides a method of detecting Staphylococcus aureus in a subject, by contacting a sample obtained from the subject with at least one detectably labeled probe of the invention or detecting in the sample identity to a sequence of the invention. The invention is also directed to kits, microarrays and detectable Staphylococcus aureus polynucleotide probes useful in detecting the presence of Staphylococcus aureus.
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公开(公告)号：US20220417043A1
公开(公告)日：2022-12-29
申请号：US17849623
申请日：2022-06-25
申请人： Arizona Board of Regents on Behalf of Northern Arizona University , Government of the United States of America, as represented by the Secretary of the Air Force
IPC分类号： H04L9/32
摘要： Systems and methods for providing authentication and secure cryptographic communication between a client and server are described. The client includes an addressable array of PUF devices. The client receives or generates a set of instructions usable to determine a range of PUF addresses. The client measures the PUF addresses and generates a first set of responses. The responses are used to encrypt a session key, which is stored, along with the instructions and a hash of the responses, at the client. Later, the client may recover the session key by using the instructions to measure the PUF again, resulting in a second set of responses. Using a response-based cryptography search engine, the client may then iteratively modify and hash the second set of responses until a response set is uncovered that matches the first response set. This modified response set may then be used to uncover the session key.
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公开(公告)号：US11533300B2
公开(公告)日：2022-12-20
申请号：US16492572
申请日：2018-03-30
摘要： The present disclosure relates to implementations of physically unclonable functions (PUFs) for cryptographic and authentication purposes. Specifically, the disclosure describes implementations of systems using PUFs that may replace existing public key infrastructures (PKIs).
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公开(公告)号：US11446353B2
公开(公告)日：2022-09-20
申请号：US16921610
申请日：2020-07-06
申请人： THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE , ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
发明人： David Engelthaler , Elizabeth Driebe , Hongwei “Holly” Yin , Michael Valentine , Donald Chow , Jolene Bowers , Paul Keim , Bridget Barker
IPC分类号： A61K31/41 , A61K31/135 , A61K38/13 , A61K31/7135 , A61K31/58 , A61K31/5377 , A61K31/5415 , A61K31/4196 , A61K31/496 , A61K31/495 , A61K45/06 , A61K31/138 , A61K31/277 , A61K31/353 , A61K31/404 , A61K31/4174 , A61K31/428 , A61K31/4741 , A61K31/609
摘要： The present invention comprises methods of treating an infection using a pharmaceutical composition comprising an active ingredient selected from Table 1. In some aspects, the infection can be caused by one or more pathogens, including fungal pathogens. For example, the infection may be Valley Fever.
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