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901 条记录 (耗时 0.051 秒)

    Dispensing Apparatus
    91.
    发明申请
    Dispensing Apparatus 有权
    点胶装置

    公开(公告)号：US20070246041A1

    公开(公告)日：2007-10-25

    申请号：US11587665

    申请日：2005-04-27

    申请人： Richard Warby

    发明人： Richard Warby

    IPC分类号： A61M15/00

    CPC分类号： A61M15/009 ,  A61M15/008 ,  A61M15/0081 ,  A61M15/0091 ,  A61M2205/0288 ,  A61M2205/3317 ,  A61M2205/8243 ,  A61M2206/14

    摘要： A pressurised metered dose inhaler (1) comprising: a reservoir (2) for containing pressurised product, a valve (9) having an inlet (11) communicating with the reservoir and an outlet (14) through which product is dispensed in use, a piece of magnetisable material (5), an armature (8) extending into proximity with the valve, and an electromagnet (7) surrounding at least a portion of the armature. Wherein the armature is coupled to, or forms part of, the valve such that controlled energisation of the electromagnet causes the armature to be either attracted to or repelled from the piece of magnetisable material one or more times to operate the valve for a controlled time period to effect dispensation of a metered dose of pressurised product from the reservoir through the valve outlet.

    摘要翻译： 一种加压计量剂量吸入器（1），包括：用于容纳加压产品的储存器（2），具有与储存器连通的入口（11）的阀（9）和在使用中通过其分配产品的出口（14） 可磁化材料片（5），延伸到阀附近的电枢（8）以及围绕电枢的至少一部分的电磁体（7）。 其中电枢联接到阀门或形成阀的一部分，使得电磁体的受控通电使衔铁被吸引或者从可磁化材料排出一次或多次，以在可控制的时间段内操作阀门 以通过阀出口从储存器分配计量剂量的加压产品。

    Method for treating diabetes mellitus in a patient
    92.
    发明授权
    Method for treating diabetes mellitus in a patient 失效
    治疗患者糖尿病的方法

    公开(公告)号：US07278419B2

    公开(公告)日：2007-10-09

    申请号：US10768371

    申请日：2004-01-30

    申请人： Igor Gonda ,  Reid M. Rubsamen ,  Stephen J. Farr

    发明人： Igor Gonda ,  Reid M. Rubsamen ,  Stephen J. Farr

    IPC分类号： A61M11/00

    CPC分类号： A61K9/007 ,  A61J7/0418 ,  A61J7/0427 ,  A61J7/0445 ,  A61K9/0073 ,  A61K9/0075 ,  A61K38/28 ,  A61M11/001 ,  A61M15/00 ,  A61M15/0031 ,  A61M15/0045 ,  A61M15/0051 ,  A61M15/0065 ,  A61M15/0066 ,  A61M15/008 ,  A61M15/0085 ,  A61M15/009 ,  A61M16/142 ,  A61M2016/0021 ,  A61M2016/0036 ,  A61M2202/062 ,  A61M2202/064 ,  A61M2205/50 ,  A61M2205/8206

    摘要： The need for the delivery of insulin by injection can be reduced or eliminated by delivering aerosolized insulin. Repeatability of dosing is obtainable by using either regular insulin or monomeric insulin. When delivering insulin (not monomeric) by inhalation, the total inhaled volume should be about the same at each delivery to obtain repeatable results. The patient can be coached (by teaching) to inhale a given amount of air and can also be coached (by teaching) to inhale at a given flow rate. Further, the rate at which blood glucose is lowered is increased by the use of monomeric insulin. Particles of insulin and monomeric insulin delivered to the surface of lung tissue will be absorbed into the circulatory system. A dry powder or a liquid insulin formulation is delivered to the patient from a mechanical or electronic hand-held, self-contained device.

    摘要翻译： 通过注射雾化胰岛素可以减少或消除通过注射输送胰岛素的需要。 给药的重复性可通过使用正常胰岛素或单体胰岛素获得。 当通过吸入输送胰岛素（非单体）时，每次输送时，总吸入体积应大致相同，以获得可重复的结果。 患者可以通过教学来吸引一定量的空气，也可以通过教导进行指导，以给定的流量进行吸气。 此外，通过使用单体胰岛素来增加血糖降低的速度。 输送到肺组织表面的胰岛素和单体胰岛素的颗粒将被吸收到循环系统中。 将干粉或液体胰岛素制剂从机械或电子手持式独立装置输送给患者。

    Aerosol processing and inhalation method and system for high dose rate aerosol drug delivery
    93.
    发明申请
    Aerosol processing and inhalation method and system for high dose rate aerosol drug delivery 有权
    用于高剂量率气雾剂药物输送的气溶胶加工和吸入方法和系统

    公开(公告)号：US20070144514A1

    公开(公告)日：2007-06-28

    申请号：US11315951

    申请日：2005-12-22

    申请人： Donovan Yeates ,  Jinghai Yi ,  Guanglin Li

    发明人： Donovan Yeates ,  Jinghai Yi ,  Guanglin Li

    IPC分类号： A61M15/00 ,  B65D83/06

    CPC分类号： A61M15/0086 ,  A61M11/042 ,  A61M11/06 ,  A61M15/008 ,  A61M2016/0036 ,  A61M2205/362 ,  A61M2205/368 ,  B01D45/08

    摘要： A method and system is disclosed which is capable of delivering at a high dose rate, respirable solid aerosols derived from aqueous- or nonaqueous-based solutions containing the desired therapeutic agent(s). The method and system comprises the integration of an aerosol generator, an aerosol evaporator, an aerosol concentrator, and an aerosol flow regulator. The aerosol generator generates 10-30 μm droplets, with a narrow size distribution. The aerosol jet is arrested by a coaxial counter-flow heated air jet, and evaporated rapidly by annular swirling heated air. Most of the air, together with the unwanted solvent vapor, is removed from the aerosol stream during the process of aerosol concentration. The output aerosol carries the dry particles to be inhaled by the patient. The respiratory-governed control of aerosol fluid generation system delivers fluid containing the test agent of interest (drug or toxin) to the aerosol generator throughout inhalation.

    摘要翻译： 公开了能够以高剂量率递送来自含有所需治疗剂的含水或非水性溶液的可呼吸固体气溶胶的方法和系统。 该方法和系统包括气溶胶发生器，气溶胶蒸发器，气溶胶浓缩器和气溶胶流量调节器的集成。 气溶胶发生器产生10-30个液滴，尺寸分布窄。 气溶胶射流被同轴逆流加热的空气射流阻止，并通过环形旋转的加热空气迅速蒸发。 在气溶胶浓缩过程中，大部分空气与不需要的溶剂蒸气一起从气溶胶流中除去。 输出的气溶胶携带干燥的颗粒被患者吸入。 呼吸控制的气溶胶液体发生系统在吸入过程中将含有感兴趣的测试剂（药物或毒素）的流体输送到气溶胶发生器。

    Applicator for dispensing bioactive compositions and methods for using the same
    94.
    发明授权
    Applicator for dispensing bioactive compositions and methods for using the same 有权
    用于分配生物活性组合物的施用器及其使用方法

    公开(公告)号：US07198044B2

    公开(公告)日：2007-04-03

    申请号：US10697615

    申请日：2003-10-29

    申请人： Kenneth E. Trueba

    发明人： Kenneth E. Trueba

    IPC分类号： A61M11/00 ,  A61M17/06

    CPC分类号： A61M15/0086 ,  A61M15/0003 ,  A61M15/008 ,  A61M15/0085 ,  A61M15/025 ,  A61M2205/3553 ,  A61M2205/52

    摘要： Bioactive agents are topically administered or delivered to a mucous membrane by a jet dispenser using inkjet technology, such as that used in printing. The dispenser propels precise volumes of droplets or powder for administration to a subject, such as being inhaled through the mouth or nose. A controller in the dispenser may control delivery of multiple different drugs, timing of drug administration, or change drug regimens in response to a changing medical condition of a patient, such as those monitored by a sensor in communication with the controller, for example to prevent an overdose. Administration methods are also provided, along with replacement kits.

    摘要翻译： 生物活性剂通过使用喷墨技术的喷射分配器局部施用或输送到粘膜，例如用于印刷的技术。 分配器推动精确体积的液滴或粉末，用于给予受试者，例如通过口或鼻吸入。 分配器中的控制器可以响应于诸如由与控制器通信的传感器监测的患者的改变的医疗状况来控制多种不同药物的递送，药物施用的时间或改变药物方案，例如以防止 过量 还提供管理方法以及更换工具包。

    Medicament dispenser
    96.
    发明申请
    Medicament dispenser 审中-公开
    药剂分配器

    公开(公告)号：US20070056585A1

    公开(公告)日：2007-03-15

    申请号：US10572916

    申请日：2004-09-21

    申请人： Michael Davies ,  Mark Hedley

    发明人： Michael Davies ,  Mark Hedley

    IPC分类号： B65D83/06 ,  A61M15/00

    CPC分类号： B05B11/3056 ,  A61M15/0065 ,  A61M15/0073 ,  A61M15/008 ,  A61M15/08 ,  B05B11/0038 ,  B65D83/201 ,  B65D83/386

    摘要： There is provided a medicament dispenser device comprising a housing including a dispensing outlet for insertion into a body cavity; a medicament discharge device moveably housed within the housing, the medicament discharge device comprising a medicament container for storing the medicament to be dispensed and a medicament dispensing mechanism for dispensing medicament from the container to the outlet; a user operable actuator moveable with respect to the medicament discharge device to apply an actuating force to the dispensing mechanism; and an actuation indicator responsive to application of the actuating force. A pre-load means is provided to the user operable actuator to prevent application of the actuating force to the dispensing mechanism and actuation indicator until a pre-determined threshold force is applied to the user operable actuator.

    摘要翻译： 提供了一种药物分配器装置，其包括壳体，该壳体包括用于插入体腔的分配出口; 药物排出装置，其可移动地容纳在所述壳体内，所述药物排出装置包括用于储存待分配的药物的药物容器和用于将药物从所述容器分配到所述出口的药物分配机构; 用户可操作的致动器，其可相对于所述药物排出装置移动，以向所述分配机构施加致动力; 以及响应于施加所述致动力的致动指示器。 向用户可操作的致动器提供预加载装置，以防止致动力施加到分配机构和致动指示器，直到预定阈值力施加到用户可操作的致动器。

    Medical dispenser, a blister card for use in the dispenser and a method of dispensing medical doses
    97.
    发明授权
    Medical dispenser, a blister card for use in the dispenser and a method of dispensing medical doses 有权
    医用分配器，用于分配器的泡罩卡和分配医疗剂量的方法

    公开(公告)号：US07170823B2

    公开(公告)日：2007-01-30

    申请号：US10934560

    申请日：2004-09-07

    申请人： Paul Erik Fabricius ,  Niels Toft Jørgensen

    发明人： Paul Erik Fabricius ,  Niels Toft Jørgensen

    IPC分类号： G04B47/00 ,  B65D83/04 ,  G06F17/00 ,  G07F11/00

    CPC分类号： A61J7/0481 ,  A61J1/035 ,  A61J7/0418 ,  A61J7/0436 ,  A61J2200/30 ,  A61M15/0045 ,  A61M15/008 ,  A61M15/0083 ,  G06F19/00 ,  G06F19/3462

    摘要： A medical dispenser being adapted to hold a number of medical doses and being adapted to determine when a user or patient gains access to one or more of the medical doses, the dispenser comprising: means for determining each of a first plurality of points in time or time intervals at which the user or patient should take a medical dose, means for detecting each of a second plurality of points in time where the user or patient gained access to the medical doses, means for providing to the user or patient information relating to a relation between the first and second pluralities, and wherein the providing means are adapted to, if the user gains access to the medication multiple times per point in time or time interval in the first plurality of points in time or time intervals, provide information relating to a relation between the pairs of one of the firs plurality of points in time or time intervals and a first of the second plurality of points in time occurring after the pertaining point in time of the first plurality or within time interval of the first plurality.

    摘要翻译： 一种医用分配器，其适于保持多个医疗剂量，并适于确定用户或患者什么时候可以访问一个或多个医学剂量，所述分配器包括：用于确定时间上的第一多个时间点或 用户或患者应接受医疗剂量的时间间隔，用于检测用户或患者获得对医疗剂量的访问的时间中的第二多个点的每个的装置，用于向用户或患者提供与一个 第一和第二多个之间的关系，并且其中，如果用户在时间或时间间隔的第一多个点中的每个时间点或时间间隔多次获得对药物的访问，则提供装置提供与 在时间或时间间隔中的第一个多个点中的一个点之间的关系和第二个多个时间点中的第一个时间点之后的关系 int在第一个多个的时间或在第一个多个的时间间隔内。

    Dose counting in metered dose inhaler
    99.
    发明申请
    Dose counting in metered dose inhaler 审中-公开
    计量剂量吸入器的剂量计数

    公开(公告)号：US20060254581A1

    公开(公告)日：2006-11-16

    申请号：US11431687

    申请日：2006-05-09

    申请人： Perry Genova ,  Dan Deaton ,  Matt Khare

    发明人： Perry Genova ,  Dan Deaton ,  Matt Khare

    IPC分类号： A61M11/00 ,  G08B3/00 ,  A62B27/00

    CPC分类号： A61M15/009 ,  A61M15/0065 ,  A61M15/008 ,  A61M2205/52

    摘要： A counter for indicating the number of doses left in a canister that is suitable for use in a metered dose inhaler. The counter is affixed to the canister and includes a module for providing an indication of the number of doses left in the canister and a triggering mechanism for updating the indication in response to activation of the inhaler.

    摘要翻译： 用于指示适合用于计量剂量吸入器的罐中留下的剂量的计数器。 该计数器固定在该罐上，并且包括一个模块，用于提供罐内留下的剂量数量的指示;以及触发机构，用于响应于吸入器的启动来更新该指示。